flecainide has been researched along with Disorders of Excessive Somnolence in 1 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Excessive daytime sleepiness (EDS) is a frequent and disabling symptom of Parkinson's disease (PD) without approved treatment." | 3.11 | THN 102 for Excessive Daytime Sleepiness Associated with Parkinson's Disease: A Phase 2a Trial. ( Azulay, JP; Bosse, B; Corvol, JC; Dauvilliers, Y; Defebvre, L; Klostermann, F; Kovacs, N; Maltête, D; Ondo, WG; Pahwa, R; Rascol, O; Rein, W; Thobois, S; Valis, M; Videnovic, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corvol, JC | 1 |
| Azulay, JP | 1 |
| Bosse, B | 1 |
| Dauvilliers, Y | 1 |
| Defebvre, L | 1 |
| Klostermann, F | 1 |
| Kovacs, N | 1 |
| Maltête, D | 1 |
| Ondo, WG | 1 |
| Pahwa, R | 1 |
| Rein, W | 1 |
| Thobois, S | 1 |
| Valis, M | 1 |
| Videnovic, A | 1 |
| Rascol, O | 1 |
1 trial available for flecainide and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
THN 102 for Excessive Daytime Sleepiness Associated with Parkinson's Disease: A Phase 2a Trial.
Topics: Disorders of Excessive Somnolence; Double-Blind Method; Drug Combinations; Flecainide; Humans; Modaf | 2022 |