flecainide has been researched along with Chronic Kidney Failure in 10 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 8.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 4.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Cardiac arrhythmias are frequent by hemodialyzed patients and may lead to the prescription of antiarrhythmic drugs among which flecainide." | 3.73 | [Be careful in using flecainide by hemodialyzed patients]. ( Aliouche, CP; Montagnac, R; Schillinger, F; Schoen, E, 2006) |
| " For patients with ventricular premature complexes, the half-life is longer (mean 20 hours), and twice-daily oral dosage is effective." | 2.37 | Metabolism of flecainide. ( Conard, GJ; Ober, RE, 1984) |
| "Flecainide intoxication is a severe intoxication that can lead to cardiogenic shock." | 1.51 | Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication. ( Heldens, M; Melman, PG; van der Nat, GAM, 2019) |
| "Flecainide is a sodium channel blocker used mainly in the treatment of supraventricular arrhythmias." | 1.35 | Paranoid psychosis and myoclonus: flecainide toxicity in renal failure. ( Lee, D; Maclean, D; Sheerin, NS; Ting, SM, 2008) |
| " The average plasma half-life was prolonged by about twofold that of healthy subjects but most patients were within the range of values for healthy subjects." | 1.27 | Pharmacokinetics of flecainide acetate in patients with severe renal impairment. ( McQuinn, RL; Walls, J; Williams, AJ, 1988) |
| " Therefore, CLCR alone is not a good predictor of plasma elimination half-life following a single oral dose of flecainide." | 1.27 | Oral flecainide pharmacokinetics in patients with impaired renal function. ( Blair, AD; Burgess, E; Conard, GJ; Cutler, RE; Forland, SC; Fox, JM; Kvam, DC; Weeks, CE, 1988) |
| " It is suggested that the dosage reduction required for patients taking flecainide during CAPD should be similar to that for patients with end-stage renal disease but not on dialysis." | 1.27 | Pharmacokinetics of flecainide in a patient undergoing continuous ambulatory peritoneal dialysis. ( Bailie, GR; Waldek, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plant, A | 1 |
| Gold, D | 1 |
| Walker, J | 1 |
| Heldens, M | 1 |
| van der Nat, GAM | 1 |
| Melman, PG | 1 |
| Kiblboeck, D | 1 |
| Braeuer-Mocker, M | 1 |
| Siostrzonek, P | 1 |
| Reisinger, J | 1 |
| Montagnac, R | 1 |
| Schoen, E | 1 |
| Aliouche, CP | 1 |
| Schillinger, F | 1 |
| Ting, SM | 1 |
| Lee, D | 1 |
| Maclean, D | 1 |
| Sheerin, NS | 1 |
| Conard, GJ | 2 |
| Ober, RE | 1 |
| Maury, P | 1 |
| Vuille, C | 1 |
| Metzger, J | 1 |
| Veragut, B | 1 |
| Schoenenberger, I | 1 |
| Elamly, A | 1 |
| Chevrolet, JC | 1 |
| Williams, AJ | 1 |
| McQuinn, RL | 1 |
| Walls, J | 1 |
| Forland, SC | 1 |
| Burgess, E | 1 |
| Blair, AD | 1 |
| Cutler, RE | 1 |
| Kvam, DC | 1 |
| Weeks, CE | 1 |
| Fox, JM | 1 |
| Bailie, GR | 1 |
| Waldek, S | 1 |
2 reviews available for flecainide and Chronic Kidney Failure
| Article | Year |
|---|---|
Metabolism of flecainide.
Topics: Animals; Anti-Arrhythmia Agents; Biotransformation; Blood Proteins; Chromatography, High Pressure Li | 1984 |
[Severe flecainide acetate poisoning. Apropos of a case].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate | 1999 |
8 other studies available for flecainide and Chronic Kidney Failure
| Article | Year |
|---|---|
More than merely potassium: an uncommon cause for sine waves in renal failure.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Kidney Failure, | 2020 |
Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Buffers; Cardiotonic Agents; Drug Overdose; Electrocardio | 2019 |
A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Block; Cardiopulmonary Resuscita | 2012 |
[Be careful in using flecainide by hemodialyzed patients].
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Flecainide; Humans; Kidney Failure, Chronic; Mal | 2006 |
Paranoid psychosis and myoclonus: flecainide toxicity in renal failure.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Diabetes Mellitus, Type 2; Dose-Response Relationship, | 2008 |
Pharmacokinetics of flecainide acetate in patients with severe renal impairment.
Topics: Administration, Oral; Adult; Female; Flecainide; Humans; Infusions, Intravenous; Kidney Failure, Chr | 1988 |
Oral flecainide pharmacokinetics in patients with impaired renal function.
Topics: Administration, Oral; Adult; Aged; Creatinine; Dose-Response Relationship, Drug; Female; Flecainide; | 1988 |
Pharmacokinetics of flecainide in a patient undergoing continuous ambulatory peritoneal dialysis.
Topics: Biological Availability; Flecainide; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal | 1988 |