flecainide has been researched along with Cardiovascular Diseases in 4 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flecainide and propafenone are antiarrhythmic drugs of the class 1C (Vaughan and Williams) commonly used for ventricular arrhythmias." | 10.17 | [Propafenone and flecainide in the therapy of ventricular arrhythmias]. ( Davini, A; Lattanzi, F; Paci, A; Paperini, L; Reisenhofer, B; Squarcini, G; Topi, A; Topi, PL, 1995) |
| "Flecainide and propafenone are antiarrhythmic drugs of the class 1C (Vaughan and Williams) commonly used for ventricular arrhythmias." | 6.17 | [Propafenone and flecainide in the therapy of ventricular arrhythmias]. ( Davini, A; Lattanzi, F; Paci, A; Paperini, L; Reisenhofer, B; Squarcini, G; Topi, A; Topi, PL, 1995) |
| "Flecainide plasma levels were higher when associated with cardiovascular side effects (mean 1063 ng/ml; range 296 to 2050 ng/ml) than when no side effects occurred (mean 609 ng/ml; range 89 to 1508 ng/ml; P less than 0." | 1.27 | Pharmacodynamics and side effects of flecainide acetate. ( Berry, D; Erlien, D; Granrud, G; Hodges, M; Krejci, J; Larson, T; Salerno, DM; Sharkey, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pappone, C | 1 |
| Augello, G | 1 |
| Sala, S | 1 |
| Gugliotta, F | 1 |
| Vicedomini, G | 1 |
| Gulletta, S | 1 |
| Paglino, G | 1 |
| Mazzone, P | 1 |
| Sora, N | 1 |
| Greiss, I | 1 |
| Santagostino, A | 1 |
| LiVolsi, L | 1 |
| Pappone, N | 1 |
| Radinovic, A | 1 |
| Manguso, F | 1 |
| Santinelli, V | 1 |
| Devin, R | 1 |
| Garrett, P | 1 |
| Anstey, C | 1 |
| Paperini, L | 1 |
| Davini, A | 1 |
| Lattanzi, F | 1 |
| Topi, A | 1 |
| Reisenhofer, B | 1 |
| Squarcini, G | 1 |
| Paci, A | 1 |
| Topi, PL | 1 |
| Salerno, DM | 1 |
| Granrud, G | 1 |
| Sharkey, P | 1 |
| Krejci, J | 1 |
| Larson, T | 1 |
| Erlien, D | 1 |
| Berry, D | 1 |
| Hodges, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Treating Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF2) Trial[NCT00340314] | Phase 4 | 198 participants | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for flecainide and Cardiovascular Diseases
| Article | Year |
|---|---|
[Propafenone and flecainide in the therapy of ventricular arrhythmias].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Diseases; Drug Evaluation; | 1995 |
2 trials available for flecainide and Cardiovascular Diseases
| Article | Year |
|---|---|
A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.
Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Diseases; | 2006 |
[Propafenone and flecainide in the therapy of ventricular arrhythmias].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Diseases; Drug Evaluation; | 1995 |
2 other studies available for flecainide and Cardiovascular Diseases
| Article | Year |
|---|---|
Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.
Topics: Adult; Anti-Arrhythmia Agents; Cardiovascular Diseases; Charcoal; Drug Overdose; Electrocardiography | 2007 |
Pharmacodynamics and side effects of flecainide acetate.
Topics: Aged; Arrhythmias, Cardiac; Cardiovascular Diseases; Dose-Response Relationship, Drug; Electrocardio | 1986 |