Page last updated: 2024-10-27

flecainide and Cardiac Diseases

flecainide has been researched along with Cardiac Diseases in 11 studies

Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).

Research Excerpts

ExcerptRelevanceReference
"Unexplained cardiac arrest (UCA) can be caused by low-penetrance genetic disorders."1.42Diagnostic Approach to Unexplained Cardiac Arrest (from the FIVI-Gen Study). ( Álvarez, M; Cózar, R; Domingo, D; Fernández Pastor, J; Gimeno, JR; Grima, EZ; Heras, RP; Jiménez-Jáimez, J; Mazuelos, F; Monserrat, L; Moriña, P; Ortiz-Genga, M; Peinado, R; Sánchez Muñoz, JJ; Segura, F; Tercedor, L, 2015)
"Oral flecainide therapy was effective in 33 of 63 patients who had tachycardia and an extranodal accessory connection."1.28Safety and efficacy of oral flecainide therapy in patients with atrioventricular re-entrant tachycardia. ( Cockrell, JL; Griffin, JC; Helmy, I; Langberg, JJ; Lee, MA; Scheinman, MM; Titus, C, 1991)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bardien-Kruger, S1
Wulff, H1
Arieff, Z1
Brink, P1
Chandy, KG1
Corfield, V1
Jiménez-Jáimez, J1
Peinado, R1
Grima, EZ1
Segura, F1
Moriña, P1
Sánchez Muñoz, JJ1
Mazuelos, F1
Cózar, R1
Gimeno, JR1
Heras, RP1
Monserrat, L1
Domingo, D1
Ortiz-Genga, M1
Fernández Pastor, J1
Álvarez, M1
Tercedor, L1
Currie, S1
Elliott, EB1
Smith, GL1
Loughrey, CM1
Janko, S1
Hoffmann, E1
Conti, CR1
Lombardi, F1
Finocchiaro, ML1
Dalla Vecchia, L1
Rech, R1
Castelli, A1
Pastine, J1
Cappiello, E1
Vincenti, A1
Landolina, M1
Latini, R1
Cavalli, A1
Gaita, F1
Giani, P1
Cockrell, JL1
Scheinman, MM1
Titus, C1
Helmy, I1
Langberg, JJ1
Lee, MA1
Griffin, JC1
Holtzman, JL1
Weeks, CE1
Kvam, DC1
Berry, DA1
Mottonen, L1
Ekholm, BP1
Chang, SF1
Conard, GJ1
Szatmáry, LJ1
Bernadet, P1
Puel, P1
Nakamura, T1
Nezuo, S1
Hasegawa, K1
Tadaoka, S1
Nakao, M1
Kakumae, S1
Inoue, S1
Kawahara, Y1
Sawayama, T1

Reviews

2 reviews available for flecainide and Cardiac Diseases

ArticleYear
Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective.
    Pharmacology & therapeutics, 2011, Volume: 131, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Pro

2011
[Drug treatment of atrial fibrillation].
    MMW Fortschritte der Medizin, 2006, Apr-13, Volume: 148, Issue:15

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti

2006

Trials

2 trials available for flecainide and Cardiac Diseases

ArticleYear
Washout of long-term treatment with flecainide and propafenone in patients with complex ventricular arrhythmias and cardiac disease. Antiarrhythmic Drug Evaluation Group.
    American heart journal, 1992, Volume: 124, Issue:2

    Topics: Arrhythmias, Cardiac; Electrocardiography; Flecainide; Heart Diseases; Humans; Male; Middle Aged; Pr

1992
Identification of drug interactions by meta-analysis of premarketing trials: the effect of smoking on the pharmacokinetics and dosage requirements for flecainide acetate.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Flecainide; Heart Diseases; Humans; Male;

1989

Other Studies

7 other studies available for flecainide and Cardiac Diseases

ArticleYear
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).
    European journal of human genetics : EJHG, 2002, Volume: 10, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart

2002
Diagnostic Approach to Unexplained Cardiac Arrest (from the FIVI-Gen Study).
    The American journal of cardiology, 2015, Sep-15, Volume: 116, Issue:6

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Catheteri

2015
What is structural heart disease?
    Clinical cardiology, 2000, Volume: 23, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Flecainide; Heart Diseases; Humans; Practice Patterns, Physician

2000
Effects of mexiletine, propafenone and flecainide on signal-averaged electrocardiogram.
    European heart journal, 1992, Volume: 13, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Electrocardiography, Ambulatory; Female; Flecainide; Heart Diseases;

1992
Safety and efficacy of oral flecainide therapy in patients with atrioventricular re-entrant tachycardia.
    Annals of internal medicine, 1991, Feb-01, Volume: 114, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Pacing, Artificial; Child; Electric Stimulation;

1991
Mechanical circulatory assistance in the management of patients in coronary care unit.
    Acta medica Hungarica, 1988, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon; Cardiac Surgical Procedures;

1988
[Hemodynamic effects of flecainide in relation to its serum concentration].
    Kokyu to junkan. Respiration & circulation, 1988, Volume: 36, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Aged; Female; Flecainide; Heart Diseases; Hemodynamics; Hum

1988