flecainide has been researched along with Brugada Syndrome in 54 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the predictive value of T-peak to T-end interval and corrected T-peak to T-end interval for predicting the positive response of the ajmaline challenge test in suspected Brugada syndrome patients." | 8.12 | T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients. ( Chokesuwattanaskul, R; Leelapatana, P; Prechawat, S; Rungpradubvong, V; Thapanasuta, M, 2022) |
| "In patients with false-negative responses to the provocative testing with flecainide, cardiac syncope predicts SCA, allowing a more extensive and individualized evaluation." | 7.88 | Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing. ( Avanzas, P; Calvo, D; Coto, E; García, D; Gómez, J; González-Vasserot, M; María de la Hera, J; Morís, C; Pablo Flórez, J; Pérez, D; Reguero, J; Rubín, J; Valverde, I, 2018) |
| " Previous reports on the long-term use of sodium channel blockers in LQT3 are sparse." | 5.48 | Long-term flecainide therapy in type 3 long QT syndrome. ( Benhorin, J; Chorin, E; Flint, N; Medina, A; Taub, R; Viskin, S, 2018) |
| "Flecainide treatment revealed coved ST elevation in all mutation carriers." | 5.40 | Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. ( Bloch Thomsen, PE; Christiansen, M; Grunnet, M; Hedley, PL; Jespersen, T; Jons, C; Kanters, JK; Stoevring, B; Yuan, L, 2014) |
| "Flecainide testing is a valid and safe tool to identify SCN5A-related BrS patients." | 5.33 | Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome. ( Bezzina, CR; Hofman, N; Meregalli, PG; Ruijter, JM; Tan, HL; Wilde, AA, 2006) |
| "This study aimed to investigate the predictive value of T-peak to T-end interval and corrected T-peak to T-end interval for predicting the positive response of the ajmaline challenge test in suspected Brugada syndrome patients." | 4.12 | T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients. ( Chokesuwattanaskul, R; Leelapatana, P; Prechawat, S; Rungpradubvong, V; Thapanasuta, M, 2022) |
| "In patients with false-negative responses to the provocative testing with flecainide, cardiac syncope predicts SCA, allowing a more extensive and individualized evaluation." | 3.88 | Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing. ( Avanzas, P; Calvo, D; Coto, E; García, D; Gómez, J; González-Vasserot, M; María de la Hera, J; Morís, C; Pablo Flórez, J; Pérez, D; Reguero, J; Rubín, J; Valverde, I, 2018) |
| "We describe a case of Brugada syndrome disclosed by fever and with non-significant alterations after a flecainide test." | 3.81 | Brugada syndrome ECG pattern and fever: too warm is bad. ( Patruno, N; Pontillo, D, 2015) |
| "The index case was clinically diagnosed with Brugada syndrome after flecainide test." | 3.80 | Brugada syndrome and p.E61X_RANGRF. ( Allegue, C; Berne, P; Brugada, J; Brugada, R; Campuzano, O; Iglesias, A; Selga, E, 2014) |
| "Between January 2000 and June 2008, all consecutive patients with new-onset AF, who after flecainide exhibited typical Brugada ECG pattern, underwent electrophysiologic, pharmacologic, and genetic testing." | 3.75 | New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance. ( Ciaccio, C; Ciconte, G; Ferrari, M; Kallergis, EM; Manguso, F; Pappone, C; Radinovic, A; Sacchi, S; Sacco, FM; Sala, S; Santinelli, V; Saviano, M; Sommariva, E; Vicedomini, G, 2009) |
| " Previous reports on the long-term use of sodium channel blockers in LQT3 are sparse." | 1.48 | Long-term flecainide therapy in type 3 long QT syndrome. ( Benhorin, J; Chorin, E; Flint, N; Medina, A; Taub, R; Viskin, S, 2018) |
| "However, the mechanisms of cardiac arrhythmias in DM1 are unknown." | 1.42 | Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1. ( Algalarrondo, V; Azibi, K; Balse, E; Beldjord, C; Coulombe, A; Duboc, D; Eymard, B; Fischmeister, R; Gourdon, G; Hatem, SN; Sebag, F; Wahbi, K, 2015) |
| "Unexplained cardiac arrest (UCA) can be caused by low-penetrance genetic disorders." | 1.42 | Diagnostic Approach to Unexplained Cardiac Arrest (from the FIVI-Gen Study). ( Álvarez, M; Cózar, R; Domingo, D; Fernández Pastor, J; Gimeno, JR; Grima, EZ; Heras, RP; Jiménez-Jáimez, J; Mazuelos, F; Monserrat, L; Moriña, P; Ortiz-Genga, M; Peinado, R; Sánchez Muñoz, JJ; Segura, F; Tercedor, L, 2015) |
| "Flecainide testing was performed at each follow-up visits ≤6 months." | 1.42 | Brugada Syndrome Phenotype Elimination by Epicardial Substrate Ablation. ( Berruezo, A; Brugada, J; Ciconte, G; Giannelli, L; Manguso, F; Pappone, C; Santinelli, V; Vicedomini, G, 2015) |
| "Flecainide treatment revealed coved ST elevation in all mutation carriers." | 1.40 | Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. ( Bloch Thomsen, PE; Christiansen, M; Grunnet, M; Hedley, PL; Jespersen, T; Jons, C; Kanters, JK; Stoevring, B; Yuan, L, 2014) |
| "The Brugada syndrome is a heterogeneous genetic disease that predisposes to life-threatening ventricular tachyarrhythmias and sudden cardiac death (SCD)." | 1.39 | Positive Brugada challenge test in V1 R-V3 R as a predictor of malignant prognosis in Brugada patients. ( Aslani, A; Emkanjoo, Z; Hashemi, A; Saber, S; Shahrzad, S; Taban, S, 2013) |
| "Flecainide testing is a valid and safe tool to identify SCN5A-related BrS patients." | 1.33 | Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome. ( Bezzina, CR; Hofman, N; Meregalli, PG; Ruijter, JM; Tan, HL; Wilde, AA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (20.37) | 29.6817 |
| 2010's | 38 (70.37) | 24.3611 |
| 2020's | 5 (9.26) | 2.80 |
| Authors | Studies |
|---|---|
| Thapanasuta, M | 1 |
| Chokesuwattanaskul, R | 1 |
| Leelapatana, P | 1 |
| Rungpradubvong, V | 1 |
| Prechawat, S | 1 |
| Vetta, G | 1 |
| Parlavecchio, A | 1 |
| Pistelli, L | 1 |
| Desalvo, P | 1 |
| Lo Savio, A | 1 |
| Magnocavallo, M | 1 |
| Caminiti, R | 1 |
| Tribuzio, A | 1 |
| Vairo, A | 1 |
| La Maestra, D | 1 |
| Vetta, F | 1 |
| Dattilo, G | 1 |
| Luzza, F | 1 |
| Di Bella, G | 1 |
| Rossini, R | 1 |
| Della Rocca, DG | 1 |
| Crea, P | 1 |
| Luna-López, R | 1 |
| Datino, T | 1 |
| Espinosa, MÁ | 1 |
| Fernández-Avilés, F | 1 |
| Arenal, Á | 1 |
| Shen, X | 1 |
| Tan, BYQ | 1 |
| Sia, CH | 1 |
| Lee, JSW | 1 |
| Dalakoti, M | 1 |
| Wang, K | 1 |
| Lim, DYZ | 1 |
| Sng, GGR | 1 |
| Lee, ECY | 1 |
| Chow, W | 1 |
| Kwan, CKW | 1 |
| Wang, LK | 1 |
| Tan, BY | 1 |
| Lim, PCY | 1 |
| Chua, KCM | 1 |
| Ho, KL | 1 |
| Lim, ETS | 1 |
| Ching, CK | 1 |
| Teo, WS | 1 |
| Chua, TSJ | 1 |
| Tan, RS | 1 |
| Yeo, TJ | 1 |
| Chong, DTT | 1 |
| Chen, CC | 1 |
| Chung, FP | 1 |
| Lin, YJ | 1 |
| Chang, SL | 1 |
| Lo, LW | 1 |
| Hu, YF | 1 |
| Tuan, TC | 1 |
| Chao, TF | 1 |
| Liao, JN | 1 |
| Lin, CY | 1 |
| Chang, TY | 1 |
| Wu, CI | 1 |
| Liu, CM | 1 |
| Chin, CG | 1 |
| Liu, SH | 1 |
| Cheng, WH | 1 |
| Chou, CY | 1 |
| Lugtu, IC | 1 |
| Chen, SA | 1 |
| Chorin, E | 1 |
| Taub, R | 1 |
| Medina, A | 1 |
| Flint, N | 1 |
| Viskin, S | 1 |
| Benhorin, J | 1 |
| Poli, S | 1 |
| Toniolo, M | 1 |
| Maiani, M | 1 |
| Zanuttini, D | 1 |
| Rebellato, L | 1 |
| Vendramin, I | 1 |
| Dametto, E | 1 |
| Bernardi, G | 1 |
| Bassi, F | 1 |
| Napolitano, C | 1 |
| Livi, U | 1 |
| Proclemer, A | 1 |
| Therasse, D | 1 |
| Sacher, F | 1 |
| Petit, B | 1 |
| Babuty, D | 1 |
| Mabo, P | 1 |
| Martins, R | 1 |
| Jesel, L | 1 |
| Maury, P | 2 |
| Pasquie, JL | 2 |
| Mansourati, J | 1 |
| Dupuis, JM | 1 |
| Kyndt, F | 1 |
| Thollet, A | 1 |
| Guyomarch, B | 1 |
| Barc, J | 1 |
| Schott, JJ | 1 |
| Le Marec, H | 1 |
| Redon, R | 1 |
| Probst, V | 1 |
| Gourraud, JB | 1 |
| Heidecker, B | 1 |
| Pablo Flórez, J | 1 |
| García, D | 1 |
| Valverde, I | 1 |
| Rubín, J | 1 |
| Pérez, D | 2 |
| González-Vasserot, M | 1 |
| Reguero, J | 2 |
| María de la Hera, J | 1 |
| Avanzas, P | 2 |
| Gómez, J | 2 |
| Coto, E | 2 |
| Morís, C | 2 |
| Calvo, D | 2 |
| El-Battrawy, I | 1 |
| Borggrefe, M | 1 |
| Lang, S | 1 |
| Zhou, X | 1 |
| Akin, I | 1 |
| Saguner, AM | 1 |
| Vatandaslar, S | 1 |
| Brunckhorst, C | 1 |
| Dubner, S | 1 |
| Azocar, D | 1 |
| Gallino, S | 1 |
| Cerantonio, AR | 1 |
| Muryan, S | 1 |
| Medrano, J | 1 |
| Bruno, C | 1 |
| Pontillo, D | 1 |
| Patruno, N | 1 |
| Hashemi, A | 1 |
| Shahrzad, S | 2 |
| Saber, S | 1 |
| Taban, S | 1 |
| Aslani, A | 1 |
| Emkanjoo, Z | 1 |
| Campuzano, O | 1 |
| Berne, P | 1 |
| Selga, E | 1 |
| Allegue, C | 1 |
| Iglesias, A | 1 |
| Brugada, J | 3 |
| Brugada, R | 2 |
| Chubb, H | 2 |
| Cooklin, M | 2 |
| Rosenthal, E | 2 |
| Anselm, DD | 1 |
| Baranchuk, A | 1 |
| Gray, B | 1 |
| McGuire, M | 1 |
| Semsarian, C | 1 |
| Medi, C | 1 |
| Kanters, JK | 1 |
| Yuan, L | 1 |
| Hedley, PL | 1 |
| Stoevring, B | 1 |
| Jons, C | 1 |
| Bloch Thomsen, PE | 1 |
| Grunnet, M | 1 |
| Christiansen, M | 1 |
| Jespersen, T | 1 |
| Nakaya, H | 1 |
| Audoubert, M | 1 |
| Cintas, P | 1 |
| Rollin, A | 1 |
| Duparc, A | 1 |
| Mondoly, P | 1 |
| Chiriac, AM | 1 |
| Acket, B | 1 |
| Zhao, X | 1 |
| Cardin, C | 1 |
| Delay, M | 1 |
| Sadron, M | 1 |
| Carrié, D | 1 |
| Galinier, M | 1 |
| Davy, JM | 1 |
| Arne-Bès, MC | 1 |
| Raczka, F | 1 |
| de-Riva-Silva, M | 1 |
| Montero-Cabezas, JM | 1 |
| Fontenla-Cerezuela, A | 1 |
| Salguero-Bodes, R | 1 |
| López-Gil, M | 1 |
| Arribas-Ynsaurriaga, F | 1 |
| Rubín, JM | 1 |
| Flórez, JP | 1 |
| García-Ruíz, JM | 1 |
| de la Hera, JM | 1 |
| Mizusawa, Y | 1 |
| Tan, HL | 2 |
| Algalarrondo, V | 1 |
| Wahbi, K | 1 |
| Sebag, F | 1 |
| Gourdon, G | 1 |
| Beldjord, C | 1 |
| Azibi, K | 1 |
| Balse, E | 1 |
| Coulombe, A | 1 |
| Fischmeister, R | 1 |
| Eymard, B | 1 |
| Duboc, D | 1 |
| Hatem, SN | 1 |
| Jiménez-Jáimez, J | 1 |
| Peinado, R | 2 |
| Grima, EZ | 1 |
| Segura, F | 1 |
| Moriña, P | 1 |
| Sánchez Muñoz, JJ | 1 |
| Mazuelos, F | 1 |
| Cózar, R | 1 |
| Gimeno, JR | 1 |
| Heras, RP | 1 |
| Monserrat, L | 1 |
| Domingo, D | 1 |
| Ortiz-Genga, M | 1 |
| Fernández Pastor, J | 1 |
| Álvarez, M | 1 |
| Tercedor, L | 1 |
| Kamakura, T | 1 |
| Wada, M | 1 |
| Nakajima, I | 1 |
| Ishibashi, K | 1 |
| Miyamoto, K | 1 |
| Okamura, H | 1 |
| Noda, T | 1 |
| Aiba, T | 1 |
| Takaki, H | 1 |
| Yasuda, S | 1 |
| Ogawa, H | 1 |
| Shimizu, W | 1 |
| Makiyama, T | 1 |
| Kimura, T | 1 |
| Kamakura, S | 1 |
| Kusano, K | 1 |
| Pappone, C | 2 |
| Berruezo, A | 1 |
| Vicedomini, G | 2 |
| Manguso, F | 2 |
| Ciconte, G | 2 |
| Giannelli, L | 1 |
| Santinelli, V | 2 |
| Robyns, T | 1 |
| Lu, HR | 1 |
| Gallacher, DJ | 1 |
| Garweg, C | 1 |
| Ector, J | 1 |
| Willems, R | 1 |
| Janssens, S | 1 |
| Nuyens, D | 1 |
| Tessitore, E | 1 |
| Ramlawi, M | 1 |
| Tobler, O | 1 |
| Sunthorn, H | 1 |
| Behr, ER | 1 |
| Camm, AJ | 1 |
| Beinart, R | 1 |
| Michailidis, A | 1 |
| Gurevitz, OT | 1 |
| Glikson, M | 1 |
| Soni, S | 1 |
| Gandhi, S | 1 |
| Radinovic, A | 1 |
| Sala, S | 1 |
| Sacco, FM | 1 |
| Saviano, M | 1 |
| Ferrari, M | 1 |
| Sommariva, E | 1 |
| Sacchi, S | 1 |
| Ciaccio, C | 1 |
| Kallergis, EM | 1 |
| Kit, YC | 1 |
| Yin, LH | 1 |
| Leung, MK | 1 |
| Gay, KP | 1 |
| Tak, WY | 1 |
| Letsas, KP | 1 |
| Weber, R | 1 |
| Astheimer, K | 1 |
| Kalusche, D | 1 |
| Arentz, T | 1 |
| Lebreiro, A | 1 |
| Sousa, A | 1 |
| Silva, A | 1 |
| Campos, J | 1 |
| Maciel, MJ | 1 |
| Martínez-Mateo, V | 1 |
| Arias, MA | 1 |
| Rodríguez-Padial, L | 1 |
| Dautova, Y | 1 |
| Zhang, Y | 1 |
| Grace, AA | 5 |
| Huang, CL | 5 |
| Martin, CA | 2 |
| Guzadhur, L | 1 |
| Lei, M | 1 |
| Bonilla-Palomas, JL | 1 |
| López-López, JM | 1 |
| Moreno-Conde, M | 1 |
| Gallego de la Sacristana, A | 1 |
| Gámez-López, AL | 1 |
| Villar-Ráez, A | 1 |
| Reiffel, JA | 1 |
| Zorzi, A | 1 |
| Migliore, F | 1 |
| Marras, E | 1 |
| Marinelli, A | 1 |
| Baritussio, A | 1 |
| Allocca, G | 1 |
| Leoni, L | 1 |
| Perazzolo Marra, M | 1 |
| Basso, C | 1 |
| Buja, G | 1 |
| Thiene, G | 1 |
| Iliceto, S | 1 |
| Delise, P | 1 |
| Corrado, D | 1 |
| Romero-Puche, AJ | 1 |
| Trigueros-Ruiz, N | 1 |
| Cerdán-Sánchez, MC | 1 |
| Pérez-Lorente, F | 1 |
| Roldán, D | 1 |
| Vicente-Vera, T | 1 |
| Barra, S | 1 |
| Providência, R | 1 |
| Nascimento, J | 1 |
| Meregalli, PG | 1 |
| Ruijter, JM | 1 |
| Hofman, N | 1 |
| Bezzina, CR | 1 |
| Wilde, AA | 1 |
| Abello, M | 1 |
| Merino, JL | 1 |
| Gnoatto, M | 1 |
| Kobza, R | 1 |
| Zuber, M | 1 |
| Erne, P | 1 |
| Stokoe, KS | 1 |
| Balasubramaniam, R | 1 |
| Goddard, CA | 2 |
| Colledge, WH | 1 |
| Sabir, IN | 1 |
| Li, LM | 1 |
| Jones, VJ | 1 |
| Junttila, MJ | 1 |
| Gonzalez, M | 1 |
| Lizotte, E | 1 |
| Benito, B | 1 |
| Vernooy, K | 1 |
| Sarkozy, A | 1 |
| Huikuri, HV | 1 |
| Brugada, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Electrical Substrate Elimination in Brugada Syndrome. Results in 135 Consecutive Patients[NCT02641431] | 135 participants (Actual) | Interventional | 2015-11-16 | Completed | |||
| Determining the Effects of Two Different Anesthesia Induction Techniques on QT Distance in Cardiac Surgery Patients With Two Different QT Measurement Techniques[NCT04706104] | 60 participants (Actual) | Observational | 2020-10-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for flecainide and Brugada Syndrome
| Article | Year |
|---|---|
Management of untreatable ventricular arrhythmias during pharmacologic challenges with sodium channel blockers for suspected Brugada syndrome.
Topics: Action Potentials; Adolescent; Adult; Aged; Aged, 80 and over; Ajmaline; Brugada Syndrome; Cardiopul | 2018 |
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
1 trial available for flecainide and Brugada Syndrome
| Article | Year |
|---|---|
Time-dependent responses to provocative testing with flecainide in the diagnosis of Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide; Follow-Up | 2015 |
51 other studies available for flecainide and Brugada Syndrome
| Article | Year |
|---|---|
T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients.
Topics: Ajmaline; Brugada Syndrome; Flecainide; Humans; Procainamide; Sodium Channel Blockers | 2022 |
The r'-Wave Algorithm: A New Diagnostic Tool to Predict the Diagnosis of Brugada Syndrome after a Sodium Channel Blocker Provocation Test.
Topics: Adult; Algorithms; Brugada Syndrome; Cohort Studies; Electrocardiography; Female; Flecainide; Humans | 2023 |
Permanent atrioventricular block after flecainide testing.
Topics: Aged; Atrioventricular Block; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Pac | 2020 |
Prevalence of Brugada Syndrome in a Large Population of Young Singaporean Men.
Topics: Adolescent; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Male; Prevalence; Singapore; | 2020 |
Spatiotemporal differences in precordial electrocardiographic amplitude before and after flecainide provocation are associated with a history of unstable ventricular arrhythmia in Brugada syndrome.
Topics: Adult; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Male | 2021 |
Long-term flecainide therapy in type 3 long QT syndrome.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Conduction System Disease; Chil | 2018 |
Sodium-channel blocker challenge in the familial screening of Brugada syndrome: Safety and predictors of positivity.
Topics: Adult; Ajmaline; Brugada Syndrome; Dose-Response Relationship, Drug; Electrocardiography; False Posi | 2017 |
When High Throughput Meets Mechanistic Studies: A State-of-the-Art Approach in Brugada Syndrome.
Topics: Anti-Arrhythmia Agents; Basic Helix-Loop-Helix Transcription Factors; Brugada Syndrome; Flecainide; | 2017 |
Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; False Negative Reactions; Fema | 2018 |
Sodium channel blockers in Brugada syndrome.
Topics: Ajmaline; Brugada Syndrome; Flecainide; Humans; Sodium Channel Blockers; Syncope | 2018 |
[CME ECG 40. Vertigo with ST elevation in V2. Brugada syndrome].
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Diagnosis, Differential; Electrocardiography; Emergency Se | 2013 |
Single oral flecainide dose to unmask type 1 Brugada syndrome electrocardiographic pattern.
Topics: Administration, Oral; Adult; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Male | 2013 |
Brugada syndrome ECG pattern and fever: too warm is bad.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Fever; Flecainide; Humans; Mi | 2015 |
Positive Brugada challenge test in V1 R-V3 R as a predictor of malignant prognosis in Brugada patients.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide | 2013 |
Brugada syndrome and p.E61X_RANGRF.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Child; Codon, Nonsense; DNA Mutational Analys | 2014 |
Brugada phenocopy with a flecainide overdose: a pharmacological dose effect?
Topics: Adolescent; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Pacing, Artificial; Drug Overdose; Ele | 2014 |
"About Brugada phenocopy": Brugada phenocopy with a flecainide overdose: a pharmacological dose effect?
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Female; Flecainide; Heart Conduction System; Humans; Volta | 2014 |
About Brugada phenocopy: Brugada phenocopy with a flecainide overdose: a pharmacological dose effect?
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Female; Flecainide; Heart Conduction System; Humans; Volta | 2014 |
Late positive flecainide challenge test for Brugada syndrome.
Topics: Brugada Syndrome; Diagnosis, Differential; Electrocardiography; Female; Flecainide; Humans; Injectio | 2014 |
Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A.
Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Family; Female; Flecaini | 2014 |
SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.
Topics: Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Family; Female; Flecainide; Humans; Long QT Syndr | 2014 |
Prevalence of type 1 Brugada ECG pattern after administration of Class 1C drugs in patients with type 1 myotonic dystrophy: Myotonic dystrophy as a part of the Brugada syndrome.
Topics: Adult; Ajmaline; Brugada Syndrome; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardi | 2014 |
Delayed positive response to a flecainide test in a patient with suspected Brugada syndrome: a worrisome finding.
Topics: Brugada Syndrome; Diagnosis, Differential; Electrocardiography; Flecainide; Humans; Male; Voltage-Ga | 2014 |
A refined protocol of flecainide testing in Brugada syndrome: from ambiguous assessment toward definite diagnosis.
Topics: Brugada Syndrome; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Male | 2015 |
Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1.
Topics: Action Potentials; Aging; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; C | 2015 |
Diagnostic Approach to Unexplained Cardiac Arrest (from the FIVI-Gen Study).
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Catheteri | 2015 |
Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, | 2016 |
Brugada Syndrome Phenotype Elimination by Epicardial Substrate Ablation.
Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Catheter Ablation; Death, Sudden | 2015 |
Evaluation of Index of Cardio-Electrophysiological Balance (iCEB) as a New Biomarker for the Identification of Patients at Increased Arrhythmic Risk.
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biomarkers, Pharmacological; Brugada Syndrome; | 2016 |
Brugada Pattern Caused by a Flecainide Overdose.
Topics: Atrial Fibrillation; Bipolar Disorder; Brugada Syndrome; Consciousness Disorders; Drug Overdose; Ele | 2017 |
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias".
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
Is flecainide dangerous in long QT-3 patients?
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Long QT S | 2009 |
Flecainide overdose causing a Brugada-type pattern on electrocardiogram in a previously well patient.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Male | 2009 |
New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Electrocardiography; Female; F | 2009 |
CASH as a mnemonic for indications of sodium bicarbonate for sodium channel blocker intoxication.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Magnesium; | 2009 |
Tpeak-Tend interval and Tpeak-Tend/QT ratio as markers of ventricular tachycardia inducibility in subjects with Brugada ECG phenotype.
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Biomarkers; Brugada Syndrome; Electrocardiography; Female; | 2010 |
Atypical ST segment elevation and ventricular fibrillation without structural heart disease: a new electrocardiographic presentation of a channelopathy?
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Channelopathies; Death, Sudden, Cardiac; Defibrillators, I | 2010 |
[Brugada electrocardiographic pattern elicited by flecainide overdose].
Topics: Adolescent; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Sodium Channel Blocke | 2011 |
Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Function; Brugada Syndrome; Cardiac Pacin | 2010 |
Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse model.
Topics: Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Electrocardiography; Elec | 2011 |
Type I Brugada electrocardiogram pattern induced by metoclopramide.
Topics: Brugada Syndrome; Dizziness; Dopamine Antagonists; Flecainide; Humans; Male; Metoclopramide; Middle | 2011 |
Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Electric | 2011 |
Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Catheter Ablation; Contraindications; | 2011 |
Should all individuals with a nondiagnostic Brugada-electrocardiogram undergo sodium-channel blocker test?
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Brugada Syndrome; Diagnosis, Differential; Diagnostic Error | 2012 |
Brugada electrocardiogram pattern induced by cannabis.
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cannabis; Electrocardiography | 2012 |
Fever outperforms flecainide test in the unmasking of type 1 Brugada syndrome electrocardiogram.
Topics: Adult; Brugada Syndrome; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiologic Techniq | 2013 |
Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome.
Topics: Adult; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Muscle | 2006 |
Negative flecainide test in Brugada syndrome patients with previous positive response.
Topics: Adolescent; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide; Human | 2006 |
[What is your diagnosis? Brugada syndrome].
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Death, Sudden, Cardiac; Defibrillators, Implantable | 2006 |
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Electr | 2007 |
Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Pacing, Artificial; Di | 2008 |