flecainide has been researched along with Bradycardia in 16 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia." | 7.79 | Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia. ( Kim, HS; Kim, SS; Pak, HN; Park, JS, 2013) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 7.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| "We present a case report describing an interaction between topical timolol maleate, verapamil, and flecainide resulting in symptomatic bradycardia." | 7.71 | Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report. ( Herd, A; Minish, T, 2002) |
| "Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia." | 3.79 | Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia. ( Kim, HS; Kim, SS; Pak, HN; Park, JS, 2013) |
| "A 2-year-old male with a history of a persistent junctional reciprocating tachycardia had been receiving flecainide 4." | 3.75 | Life-threatening flecainide intoxication in a young child secondary to medication error. ( Buffo-Sequiera, I; D'Alessandro, LC; Freeman, D; Gloor, J; Rieder, MJ, 2009) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 3.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| "We present a case report describing an interaction between topical timolol maleate, verapamil, and flecainide resulting in symptomatic bradycardia." | 3.71 | Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report. ( Herd, A; Minish, T, 2002) |
| "Guidelines recommend that initial trial of a "pill-in-the-pocket" (PIP) Class 1C antiarrhythmic drug (AAD) for cardioversion of atrial fibrillation (AF) be performed in a monitored setting because of the potential for adverse reactions." | 1.72 | Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation. ( Arkles, JS; Callans, DJ; Deo, R; Dixit, S; Epstein, AE; Frankel, DS; Guandalini, GS; Hyman, MC; Jarrah, AA; Lin, D; Marchlinski, FE; Markman, TM; Mustin, E; Nazarian, S; Riley, M; Santangeli, P; Schaller, RD; Supple, GE; Tian, Y, 2022) |
| " It is associated with a potent adverse effect profile; however, the effects of flecainide toxicity in the setting of a pacemaker have not been well described." | 1.51 | Flecainide Toxicity Resulting in Pacemaker Latency and Intermittent Failure to Capture. ( Akpunonu, P; Baum, R; Catanzaro, J; Elayi, CS; Rutland, J; Suffredini, JM, 2019) |
| "Flecainide intoxication is a severe intoxication that can lead to cardiogenic shock." | 1.51 | Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication. ( Heldens, M; Melman, PG; van der Nat, GAM, 2019) |
| "Tachycardia was observed in 15% of cases (three cases of supraventricular tachycardia [SVT] and two cases of auricular flutter [AF])." | 1.31 | [Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases]. ( Dubos, JP; Dufour, P; Puech, F; Subtil, D; Vaast, P; Vaksmann, G; Valat, AS; Vautier-Rit, S, 2000) |
| "Flecainide acetate is a potent class Ic anti-arrhythmic drug with major sodium channel blocking actions." | 1.30 | Survival in a case of life-threatening flecainide overdose. ( Bourke, JP; Gascoigne, AD; Hanley, NA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Markman, TM | 1 |
| Jarrah, AA | 1 |
| Tian, Y | 1 |
| Mustin, E | 1 |
| Guandalini, GS | 1 |
| Lin, D | 1 |
| Epstein, AE | 1 |
| Hyman, MC | 1 |
| Deo, R | 1 |
| Supple, GE | 1 |
| Arkles, JS | 1 |
| Dixit, S | 1 |
| Schaller, RD | 1 |
| Santangeli, P | 1 |
| Nazarian, S | 1 |
| Riley, M | 1 |
| Callans, DJ | 1 |
| Marchlinski, FE | 1 |
| Frankel, DS | 1 |
| Suffredini, JM | 1 |
| Rutland, J | 1 |
| Akpunonu, P | 1 |
| Baum, R | 1 |
| Catanzaro, J | 1 |
| Elayi, CS | 1 |
| Plant, A | 1 |
| Gold, D | 1 |
| Walker, J | 1 |
| Heldens, M | 1 |
| van der Nat, GAM | 1 |
| Melman, PG | 1 |
| D'Alessandro, LC | 1 |
| Rieder, MJ | 1 |
| Gloor, J | 1 |
| Freeman, D | 1 |
| Buffo-Sequiera, I | 1 |
| Kim, HS | 1 |
| Pak, HN | 1 |
| Park, JS | 1 |
| Kim, SS | 1 |
| Aliot, E | 1 |
| De Roy, L | 1 |
| Capucci, A | 1 |
| Hernández, J | 1 |
| Denjoy, I | 1 |
| Lupoglazoff, JM | 1 |
| Coumel, P | 1 |
| Trombert, V | 1 |
| Barro, J | 1 |
| Yasui, RK | 1 |
| Culclasure, TF | 1 |
| Kaufman, D | 1 |
| Freed, CR | 1 |
| Hanley, NA | 1 |
| Bourke, JP | 1 |
| Gascoigne, AD | 1 |
| Vautier-Rit, S | 1 |
| Dufour, P | 1 |
| Vaksmann, G | 1 |
| Subtil, D | 1 |
| Vaast, P | 1 |
| Valat, AS | 1 |
| Dubos, JP | 1 |
| Puech, F | 1 |
| Abraham, P | 1 |
| Minish, T | 1 |
| Herd, A | 1 |
| Guarnieri, T | 1 |
| Tomaselli, G | 1 |
| Griffith, LS | 1 |
| Brinker, J | 1 |
| Weissenburger, J | 1 |
| Davy, JM | 1 |
| Chézalviel, F | 1 |
| Ertzbischoff, O | 1 |
| Poirier, JM | 1 |
| Engel, F | 1 |
| Lainée, P | 1 |
| Penin, E | 1 |
| Motté, G | 1 |
| Cheymol, G | 1 |
| Köppel, C | 1 |
| Oberdisse, U | 1 |
| Heinemeyer, G | 1 |
16 other studies available for flecainide and Bradycardia
| Article | Year |
|---|---|
Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Female; Flecainide; Humans; H | 2022 |
Flecainide Toxicity Resulting in Pacemaker Latency and Intermittent Failure to Capture.
Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; El | 2019 |
More than merely potassium: an uncommon cause for sine waves in renal failure.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Kidney Failure, | 2020 |
Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Buffers; Cardiotonic Agents; Drug Overdose; Electrocardio | 2019 |
Life-threatening flecainide intoxication in a young child secondary to medication error.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Bradycardia; Cardiopulmonary Resuscitation; Child, Pre | 2009 |
Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Female; Flecainide; Humans; Torsade | 2013 |
Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Delayed-Ac | 2003 |
[Bradycardia due to blocked atrial bigeminy: ECG].
Topics: Aged; Anti-Arrhythmia Agents; Atrial Premature Complexes; Bradycardia; Electrocardiography; Flecaini | 2008 |
Flecainide overdose: is cardiopulmonary support the treatment?
Topics: Adult; Anti-Arrhythmia Agents; Bradycardia; Cardiopulmonary Bypass; Drug Overdose; Fatal Outcome; Fe | 1997 |
Survival in a case of life-threatening flecainide overdose.
Topics: Adolescent; Anti-Arrhythmia Agents; Bradycardia; Creatine Kinase; Drug Overdose; Electrocardiography | 1998 |
[Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Echocardiog | 2000 |
Supraventricular tachycardia with hydrops in a 27-week premature baby.
Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Hydrops Fetalis; Infan | 2001 |
Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agent | 2002 |
The interaction of antiarrhythmic drugs and the energy for cardioversion of chronic atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cerebrovascular Disorders; Chr | 1991 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, A | 1991 |
Clinical course and outcome in class IC antiarrhythmic overdose.
Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio | 1990 |