flecainide has been researched along with Bradyarrhythmia in 16 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia." | 7.79 | Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia. ( Kim, HS; Kim, SS; Pak, HN; Park, JS, 2013) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 7.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| "We present a case report describing an interaction between topical timolol maleate, verapamil, and flecainide resulting in symptomatic bradycardia." | 7.71 | Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report. ( Herd, A; Minish, T, 2002) |
| "Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia." | 3.79 | Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia. ( Kim, HS; Kim, SS; Pak, HN; Park, JS, 2013) |
| "A 2-year-old male with a history of a persistent junctional reciprocating tachycardia had been receiving flecainide 4." | 3.75 | Life-threatening flecainide intoxication in a young child secondary to medication error. ( Buffo-Sequiera, I; D'Alessandro, LC; Freeman, D; Gloor, J; Rieder, MJ, 2009) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 3.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| "We present a case report describing an interaction between topical timolol maleate, verapamil, and flecainide resulting in symptomatic bradycardia." | 3.71 | Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report. ( Herd, A; Minish, T, 2002) |
| "Guidelines recommend that initial trial of a "pill-in-the-pocket" (PIP) Class 1C antiarrhythmic drug (AAD) for cardioversion of atrial fibrillation (AF) be performed in a monitored setting because of the potential for adverse reactions." | 1.72 | Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation. ( Arkles, JS; Callans, DJ; Deo, R; Dixit, S; Epstein, AE; Frankel, DS; Guandalini, GS; Hyman, MC; Jarrah, AA; Lin, D; Marchlinski, FE; Markman, TM; Mustin, E; Nazarian, S; Riley, M; Santangeli, P; Schaller, RD; Supple, GE; Tian, Y, 2022) |
| " It is associated with a potent adverse effect profile; however, the effects of flecainide toxicity in the setting of a pacemaker have not been well described." | 1.51 | Flecainide Toxicity Resulting in Pacemaker Latency and Intermittent Failure to Capture. ( Akpunonu, P; Baum, R; Catanzaro, J; Elayi, CS; Rutland, J; Suffredini, JM, 2019) |
| "Flecainide intoxication is a severe intoxication that can lead to cardiogenic shock." | 1.51 | Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication. ( Heldens, M; Melman, PG; van der Nat, GAM, 2019) |
| "Tachycardia was observed in 15% of cases (three cases of supraventricular tachycardia [SVT] and two cases of auricular flutter [AF])." | 1.31 | [Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases]. ( Dubos, JP; Dufour, P; Puech, F; Subtil, D; Vaast, P; Vaksmann, G; Valat, AS; Vautier-Rit, S, 2000) |
| "Flecainide acetate is a potent class Ic anti-arrhythmic drug with major sodium channel blocking actions." | 1.30 | Survival in a case of life-threatening flecainide overdose. ( Bourke, JP; Gascoigne, AD; Hanley, NA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Markman, TM | 1 |
| Jarrah, AA | 1 |
| Tian, Y | 1 |
| Mustin, E | 1 |
| Guandalini, GS | 1 |
| Lin, D | 1 |
| Epstein, AE | 1 |
| Hyman, MC | 1 |
| Deo, R | 1 |
| Supple, GE | 1 |
| Arkles, JS | 1 |
| Dixit, S | 1 |
| Schaller, RD | 1 |
| Santangeli, P | 1 |
| Nazarian, S | 1 |
| Riley, M | 1 |
| Callans, DJ | 1 |
| Marchlinski, FE | 1 |
| Frankel, DS | 1 |
| Suffredini, JM | 1 |
| Rutland, J | 1 |
| Akpunonu, P | 1 |
| Baum, R | 1 |
| Catanzaro, J | 1 |
| Elayi, CS | 1 |
| Plant, A | 1 |
| Gold, D | 1 |
| Walker, J | 1 |
| Heldens, M | 1 |
| van der Nat, GAM | 1 |
| Melman, PG | 1 |
| D'Alessandro, LC | 1 |
| Rieder, MJ | 1 |
| Gloor, J | 1 |
| Freeman, D | 1 |
| Buffo-Sequiera, I | 1 |
| Kim, HS | 1 |
| Pak, HN | 1 |
| Park, JS | 1 |
| Kim, SS | 1 |
| Aliot, E | 1 |
| De Roy, L | 1 |
| Capucci, A | 1 |
| Hernández, J | 1 |
| Denjoy, I | 1 |
| Lupoglazoff, JM | 1 |
| Coumel, P | 1 |
| Trombert, V | 1 |
| Barro, J | 1 |
| Yasui, RK | 1 |
| Culclasure, TF | 1 |
| Kaufman, D | 1 |
| Freed, CR | 1 |
| Hanley, NA | 1 |
| Bourke, JP | 1 |
| Gascoigne, AD | 1 |
| Vautier-Rit, S | 1 |
| Dufour, P | 1 |
| Vaksmann, G | 1 |
| Subtil, D | 1 |
| Vaast, P | 1 |
| Valat, AS | 1 |
| Dubos, JP | 1 |
| Puech, F | 1 |
| Abraham, P | 1 |
| Minish, T | 1 |
| Herd, A | 1 |
| Guarnieri, T | 1 |
| Tomaselli, G | 1 |
| Griffith, LS | 1 |
| Brinker, J | 1 |
| Weissenburger, J | 1 |
| Davy, JM | 1 |
| Chézalviel, F | 1 |
| Ertzbischoff, O | 1 |
| Poirier, JM | 1 |
| Engel, F | 1 |
| Lainée, P | 1 |
| Penin, E | 1 |
| Motté, G | 1 |
| Cheymol, G | 1 |
| Köppel, C | 1 |
| Oberdisse, U | 1 |
| Heinemeyer, G | 1 |
16 other studies available for flecainide and Bradyarrhythmia
| Article | Year |
|---|---|
Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Female; Flecainide; Humans; H | 2022 |
Flecainide Toxicity Resulting in Pacemaker Latency and Intermittent Failure to Capture.
Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; El | 2019 |
More than merely potassium: an uncommon cause for sine waves in renal failure.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Kidney Failure, | 2020 |
Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Buffers; Cardiotonic Agents; Drug Overdose; Electrocardio | 2019 |
Life-threatening flecainide intoxication in a young child secondary to medication error.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Bradycardia; Cardiopulmonary Resuscitation; Child, Pre | 2009 |
Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Female; Flecainide; Humans; Torsade | 2013 |
Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Delayed-Ac | 2003 |
[Bradycardia due to blocked atrial bigeminy: ECG].
Topics: Aged; Anti-Arrhythmia Agents; Atrial Premature Complexes; Bradycardia; Electrocardiography; Flecaini | 2008 |
Flecainide overdose: is cardiopulmonary support the treatment?
Topics: Adult; Anti-Arrhythmia Agents; Bradycardia; Cardiopulmonary Bypass; Drug Overdose; Fatal Outcome; Fe | 1997 |
Survival in a case of life-threatening flecainide overdose.
Topics: Adolescent; Anti-Arrhythmia Agents; Bradycardia; Creatine Kinase; Drug Overdose; Electrocardiography | 1998 |
[Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Echocardiog | 2000 |
Supraventricular tachycardia with hydrops in a 27-week premature baby.
Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Hydrops Fetalis; Infan | 2001 |
Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agent | 2002 |
The interaction of antiarrhythmic drugs and the energy for cardioversion of chronic atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cerebrovascular Disorders; Chr | 1991 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, A | 1991 |
Clinical course and outcome in class IC antiarrhythmic overdose.
Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio | 1990 |