flecainide has been researched along with Blood Pressure, High in 10 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flecainide acetate instant release (LI) has been prescribed for years in the prevention of atrial fibrillation (AF) relapse after sinus rate conversion." | 9.12 | [Flecainide controlled-release for prevention of atrial fibrillation relapse]. ( Chatelin, A; Jaillon, P; Mary-Krause, M; Simon, T; Thuault, M, 2006) |
| "Sixty-two patients with recent-onset (less than or equal to 1 week) atrial fibrillation (New York Heart Association functional class 1 and 2) were randomized in a single-blind study to 1 of the following treatment groups: (1) flecainide (300 mg) as a single oral loading dose; or (2) amiodarone (5 mg/kg) as an intravenous bolus, followed by 1." | 9.07 | Effectiveness of loading oral flecainide for converting recent-onset atrial fibrillation to sinus rhythm in patients without organic heart disease or with only systemic hypertension. ( Binetti, N; Boriani, G; Capucci, A; Cavazza, M; Fontana, G; Lenzi, T; Magnani, B; Trisolino, G, 1992) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 8.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Flecainide acetate instant release (LI) has been prescribed for years in the prevention of atrial fibrillation (AF) relapse after sinus rate conversion." | 5.12 | [Flecainide controlled-release for prevention of atrial fibrillation relapse]. ( Chatelin, A; Jaillon, P; Mary-Krause, M; Simon, T; Thuault, M, 2006) |
| "Sixty-two patients with recent-onset (less than or equal to 1 week) atrial fibrillation (New York Heart Association functional class 1 and 2) were randomized in a single-blind study to 1 of the following treatment groups: (1) flecainide (300 mg) as a single oral loading dose; or (2) amiodarone (5 mg/kg) as an intravenous bolus, followed by 1." | 5.07 | Effectiveness of loading oral flecainide for converting recent-onset atrial fibrillation to sinus rhythm in patients without organic heart disease or with only systemic hypertension. ( Binetti, N; Boriani, G; Capucci, A; Cavazza, M; Fontana, G; Lenzi, T; Magnani, B; Trisolino, G, 1992) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 4.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Amiodarone was the most widely used active compound (82%) and apparently the most effective." | 1.39 | [Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs]. ( Alegret, JM; Freire, F; Romero-Menor, C; Viñolas, X, 2013) |
| "Flecainide has been shown to reduce salt absorption in animal bowel." | 1.34 | Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics. ( Khavandi, A; Walker, PR, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lip, GY | 1 |
| Fauchier, L | 1 |
| Freedman, SB | 1 |
| Van Gelder, I | 1 |
| Natale, A | 1 |
| Gianni, C | 1 |
| Nattel, S | 1 |
| Potpara, T | 1 |
| Rienstra, M | 1 |
| Tse, HF | 1 |
| Lane, DA | 1 |
| Viñolas, X | 1 |
| Freire, F | 1 |
| Romero-Menor, C | 1 |
| Alegret, JM | 1 |
| Simon, T | 1 |
| Mary-Krause, M | 1 |
| Chatelin, A | 1 |
| Thuault, M | 1 |
| Jaillon, P | 1 |
| Pappone, C | 1 |
| Augello, G | 1 |
| Sala, S | 1 |
| Gugliotta, F | 1 |
| Vicedomini, G | 1 |
| Gulletta, S | 1 |
| Paglino, G | 1 |
| Mazzone, P | 1 |
| Sora, N | 1 |
| Greiss, I | 1 |
| Santagostino, A | 1 |
| LiVolsi, L | 1 |
| Pappone, N | 1 |
| Radinovic, A | 1 |
| Manguso, F | 1 |
| Santinelli, V | 1 |
| Khavandi, A | 1 |
| Walker, PR | 1 |
| Meurin, P | 1 |
| Larrazet, F | 1 |
| Weber, H | 1 |
| Bourmayan, C | 1 |
| Maury, P | 1 |
| Vuille, C | 1 |
| Metzger, J | 1 |
| Veragut, B | 1 |
| Schoenenberger, I | 1 |
| Elamly, A | 1 |
| Chevrolet, JC | 1 |
| Capucci, A | 1 |
| Lenzi, T | 1 |
| Boriani, G | 1 |
| Trisolino, G | 1 |
| Binetti, N | 1 |
| Cavazza, M | 1 |
| Fontana, G | 1 |
| Magnani, B | 1 |
| Mikloweit, P | 1 |
| Bienmüller, H | 1 |
| Crijns, HJ | 1 |
| Kingma, JH | 1 |
| Viersma, JW | 1 |
| Lie, KI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dual Shock Versus Single Shock Synchronized External Direct Current Cardioversion for Atrial Fibrillation - A Double-blinded Randomized Trial[NCT03943693] | Phase 4 | 100 participants (Actual) | Interventional | 2019-04-01 | Terminated (stopped due to Poor enrollment) | ||
| A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Treating Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF2) Trial[NCT00340314] | Phase 4 | 198 participants | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for flecainide and Blood Pressure, High
| Article | Year |
|---|---|
Atrial fibrillation.
Topics: Ablation Techniques; Anticoagulants; Aspirin; Atrial Fibrillation; Dizziness; Dyspnea; Electric Coun | 2016 |
[Severe flecainide acetate poisoning. Apropos of a case].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate | 1999 |
3 trials available for flecainide and Blood Pressure, High
| Article | Year |
|---|---|
[Flecainide controlled-release for prevention of atrial fibrillation relapse].
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Delayed-Action Preparations; Elec | 2006 |
A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.
Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Diseases; | 2006 |
Effectiveness of loading oral flecainide for converting recent-onset atrial fibrillation to sinus rhythm in patients without organic heart disease or with only systemic hypertension.
Topics: Administration, Oral; Adult; Aged; Amiodarone; Atrial Fibrillation; Electrocardiography, Ambulatory; | 1992 |
5 other studies available for flecainide and Blood Pressure, High
| Article | Year |
|---|---|
[Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Mass Index; Comorbidity; Diabete | 2013 |
Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bendroflumethiazide; Diuretics; Drug Interactions; Ele | 2007 |
[Iatrogenic acute renal failure caused by overdosage of flecainide acetate].
Topics: Acute Kidney Injury; Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-In | 1998 |
[Drug-induced intrahepatic cholestasis caused by flecainide acetate and enalapril].
Topics: Aged; Cholestasis, Intrahepatic; Drug Therapy, Combination; Enalapril; Female; Flecainide; Heart Fai | 1987 |
Transient giant inverted T waves during flecainide intoxication.
Topics: Electrocardiography; Female; Flecainide; Humans; Hypertension; Middle Aged | 1987 |