Page last updated: 2024-10-27

flecainide and Anterior Fascicular Block

flecainide has been researched along with Anterior Fascicular Block in 31 studies

Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).

Research Excerpts

ExcerptRelevanceReference
"This study sought to compare the differences between procainamide and flecainide to stress the His-Purkinje system during electrophysiological study (EPS) in patients with syncope and bundle branch block (BBB)."7.91Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration. ( Ferreira-Gonzalez, I; Francisco-Pasqual, J; García-Dorado, D; Martin-Sanchez, G; Moya-Mitjans, A; Oristrell, G; Perez-Rodon, J; Rivas-Gandara, N; Roca-Luque, I; Rodríguez-García, J; Santos-Ortega, A, 2019)
"The flecainide test is widely used in Brugada syndrome."7.72Flecainide test in Brugada syndrome: a reproducible but risky tool. ( Ceriotti, C; Galimberti, P; Gasparini, M; Mantica, M; Napolitano, C; Priori, SG; Simonini, S, 2003)
"This study sought to compare the differences between procainamide and flecainide to stress the His-Purkinje system during electrophysiological study (EPS) in patients with syncope and bundle branch block (BBB)."3.91Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration. ( Ferreira-Gonzalez, I; Francisco-Pasqual, J; García-Dorado, D; Martin-Sanchez, G; Moya-Mitjans, A; Oristrell, G; Perez-Rodon, J; Rivas-Gandara, N; Roca-Luque, I; Rodríguez-García, J; Santos-Ortega, A, 2019)
"The flecainide test is widely used in Brugada syndrome."3.72Flecainide test in Brugada syndrome: a reproducible but risky tool. ( Ceriotti, C; Galimberti, P; Gasparini, M; Mantica, M; Napolitano, C; Priori, SG; Simonini, S, 2003)
"These findings demonstrate that, in Brugada syndrome, spontaneous or ajmaline-induced changes in the surface ECG may be paralleled by significant variations in the right ventricular endocardial electrogram that may result in ICD malfunction."3.70Spatial and temporal heterogeneity of depolarization and repolarization may complicate implantable cardioverter defibrillator therapy in Brugada syndrome. ( Bella, PD; Carbucicchio, C; Schmidinger, H; Stix, G, 2000)
"Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)."2.69Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000)
"Patients with heart failure and left bundle branch block (LBBB) are frequently treated with biventricular pacing (BiVP)."1.40Electrophysiological and hemodynamic effects of vernakalant and flecainide during cardiac resynchronization in dyssynchronous canine hearts. ( Auricchio, A; Houthuizen, P; Kuiper, M; Maessen, JG; Prinzen, FW; Strik, M; van Middendorp, LB, 2014)
"Left bundle branch block was induced in 12 canines."1.40Electrophysiological and haemodynamic effects of vernakalant and flecainide in dyssynchronous canine hearts. ( Auricchio, A; Houthuizen, P; Kuiper, M; Maessen, JG; Prinzen, FW; Strik, M; van Middendorp, LB, 2014)
"Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia."1.39Arrhythmogenic effect of flecainide toxicity. ( Bonnefoy, E; Courand, PY; Kirkorian, G; Mullier, A; Ranc, S; Sibellas, F, 2013)
"The flecainide test was negative in 14 and positive in 18 subjects."1.32QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome. ( Anaclerio, M; Forleo, C; Guida, P; Iacoviello, M; Manghisi, A; Massari, F; Mastropasqua, F; Pitzalis, MV; Rizzon, P; Sorrentino, S; Troccoli, R, 2003)
"He had incomplete left bundle branch block with left-axis deviation."1.31His-Purkinje system reentry as a proarrhythmic effect of flecainide. ( Barra, N; Cellarier, G; Chalvidan, T; Colin, R; Deharo, JC; Djiane, P; Peyre, JP; Savon, N, 2000)
"Flecainide acetate was given intravenously; administration was stopped because of development of a significant increase in the QRS duration, existence of prominent deep Q waves and marked ST elevation in leads V1 to V4."1.28Pseudo infarction ECG pattern occurring during intravenous treatment with flecainide acetate. ( Arnold, AE; Burgersdijk, C; Ruiter, JH; van Aubel, KJ, 1992)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's5 (16.13)18.2507
2000's16 (51.61)29.6817
2010's6 (19.35)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Rosenthal, DG1
Lee, BK1
Scheinman, MM1
Candanedo Ocaña, F1
Martín Toro, MA1
Camacho Jurado, FJ1
Martín Hidalgo, M1
González Pérez, PJ1
Herruzo Rojas, MS1
Morales Ponce, FJ1
Evans, WN1
Acherman, RJ1
Law, IH1
Von Bergen, NH1
Samson, RA1
Restrepo, H1
Roca-Luque, I1
Francisco-Pasqual, J1
Oristrell, G1
Rodríguez-García, J1
Santos-Ortega, A1
Martin-Sanchez, G1
Rivas-Gandara, N1
Perez-Rodon, J1
Ferreira-Gonzalez, I1
García-Dorado, D1
Moya-Mitjans, A1
Lokhandwala, Y1
Kumar, B1
Courand, PY1
Sibellas, F1
Ranc, S1
Mullier, A1
Kirkorian, G1
Bonnefoy, E1
van Middendorp, LB2
Strik, M2
Houthuizen, P2
Kuiper, M2
Maessen, JG2
Auricchio, A2
Prinzen, FW2
Tanel, RE1
Cabezón Ruiz, S1
Errazquin Sáenz de Tejada, F1
Pedrote Martínez, A1
Morán Risco, JE1
Marín Morgado, J1
Fernández Pérez, JM1
Gasparini, M1
Priori, SG2
Mantica, M1
Napolitano, C2
Galimberti, P1
Ceriotti, C1
Simonini, S1
Mok, NS1
Chan, NY1
Chahine, M1
Baroudi, G1
Pitzalis, MV1
Anaclerio, M1
Iacoviello, M1
Forleo, C1
Guida, P1
Troccoli, R1
Massari, F1
Mastropasqua, F1
Sorrentino, S1
Manghisi, A1
Rizzon, P1
Hudson, CJ1
Whitner, TE1
Rinaldi, MJ1
Littmann, L1
Beldner, S1
Lin, D1
Marchlinski, FE1
Sinha, MK1
Dasgupta, D1
Lyons, JP1
Nishizaki, M1
Fujii, H1
Sakurada, H1
Kimura, A1
Hiraoka, M1
Fish, JM1
Antzelevitch, C3
Wolpert, C1
Echternach, C1
Veltmann, C1
Thomas, GP1
Spehl, S1
Streitner, F1
Kuschyk, J1
Schimpf, R1
Haase, KK1
Borggrefe, M1
Nattel, S1
Haghjoo, M1
Arya, A1
Emkanjoo, Z1
Sadr-Ameli, MA1
Schöneberger, A1
Schmidt, K1
Panagides, D1
Bory, M1
Bonnet, JL1
Yvorra, S1
Desfossez, L1
Savin, B1
Ebagosti, A1
Van de Walle, JP1
Randazzo, DN1
Schweitzer, P1
Stein, E1
Banas, JS1
Winters, SL1
Chalvidan, T1
Cellarier, G1
Deharo, JC1
Colin, R1
Savon, N1
Barra, N1
Peyre, JP1
Djiane, P1
Stix, G1
Bella, PD1
Carbucicchio, C1
Schmidinger, H1
Shimizu, W1
Suyama, K1
Kurita, T1
Taguchi, A1
Aihara, N1
Takaki, H1
Sunagawa, K1
Kamakura, S1
van Aubel, KJ1
Ruiter, JH1
Arnold, AE1
Burgersdijk, C1
Blakeman, BP1
Wilber, D1
Yang, XS1
Sun, JP1
Zhi, GN1
Crijns, HJ1
van Gelder, IC1
Lie, KI1

Reviews

1 review available for flecainide and Anterior Fascicular Block

ArticleYear
Flecainide induced atrial tachycardia with 1:1 ventricular conduction during exercise testing.
    Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:9

    Topics: Aged; Atrial Function; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Exercise T

1994

Trials

1 trial available for flecainide and Anterior Fascicular Block

ArticleYear
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2000, Volume: 11, Issue:12

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain

2000

Other Studies

29 other studies available for flecainide and Anterior Fascicular Block

ArticleYear
Incessant multiform ectopy in a young woman: What is the mechanism and treatment?
    Heart rhythm, 2021, Volume: 18, Issue:9

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Premature Complexes; Bundle-Branch Block; Echocardiography; El

2021
Left bundle branch block and severe ventricular dysfunction due to flecainide toxicity: a case report.
    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 2023, Volume: 35, Issue:2

    Topics: Arrhythmias, Cardiac; Bundle-Branch Block; Flecainide; Humans; Ventricular Dysfunction

2023
Neonatal complex arrhythmias possibly related to a TTN mutation.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Connectin; Electrocardiography; Fetal Monit

2017
Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration.
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Bundle-Branch Block; Electrocardiography; Electrophysiologic Techniques, Ca

2019
Flecainide to Unmask Infranodal Disease: A Better Sieve?
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2

    Topics: Bundle-Branch Block; Flecainide; Humans; Procainamide; Syncope

2019
Arrhythmogenic effect of flecainide toxicity.
    Cardiology journal, 2013, Volume: 20, Issue:2

    Topics: Adenosine Triphosphate; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Fema

2013
Electrophysiological and hemodynamic effects of vernakalant and flecainide during cardiac resynchronization in dyssynchronous canine hearts.
    Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:1

    Topics: Animals; Anisoles; Anti-Arrhythmia Agents; Blood Pressure; Bundle-Branch Block; Cardiac Pacing, Arti

2014
Electrophysiological and haemodynamic effects of vernakalant and flecainide in dyssynchronous canine hearts.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2014, Volume: 16, Issue:8

    Topics: Action Potentials; Animals; Anisoles; Anti-Arrhythmia Agents; Blood Pressure; Bundle-Branch Block; C

2014
ECGs in the ED.
    Pediatric emergency care, 2008, Volume: 24, Issue:11

    Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Emergency Service, Hospital; Fleca

2008
[Normal conventional electrocardiogram with negative pharmacological stress test does not rule out Brugada syndrome].
    Revista espanola de cardiologia, 2003, Volume: 56, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardiography; Exe

2003
Flecainide test in Brugada syndrome: a reproducible but risky tool.
    Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:1P2

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardi

2003
A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia.
    Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bundle-Branch Block; Cholangitis; Death, Sudden, Cardi

2003
QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome.
    Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9

    Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Heart C

2003
Brugada electrocardiographic pattern elicited by inadvertent flecainide overdose.
    Pacing and clinical electrophysiology : PACE, 2004, Volume: 27, Issue:9

    Topics: Aged; Bundle-Branch Block; Drug Overdose; Electrocardiography; Flecainide; Humans; Male

2004
Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.
    The American journal of cardiology, 2004, Nov-01, Volume: 94, Issue:9

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bundle-Branch Block; Dose-Response Relationship, Drug;

2004
Flecainide challenge test for the diagnosis of Brugada syndrome.
    Postgraduate medical journal, 2004, Volume: 80, Issue:950

    Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Flecainide; Humans; Male; Middle A

2004
Spontaneous T wave alternans in a patient with Brugada syndrome--responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing.
    Journal of cardiovascular electrophysiology, 2005, Volume: 16, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Death, Sudden, Cardi

2005
Role of sodium and calcium channel block in unmasking the Brugada syndrome.
    Heart rhythm, 2004, Volume: 1, Issue:2

    Topics: Ajmaline; Animals; Bundle-Branch Block; Calcium Channel Blockers; Dogs; Electrocardiography; Flecain

2004
Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome.
    Heart rhythm, 2005, Volume: 2, Issue:3

    Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Bundle-Branch Block; Dogs; Electrocardiography; Flecainid

2005
Are all sodium channel blockers created equal? Clinical-basic correlations based on observations in Brugada syndrome.
    Heart rhythm, 2005, Volume: 2, Issue:3

    Topics: Ajmaline; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Flecainide; Heart Conduc

2005
Clinical and electrophysiologic profile of Brugada syndrome in Iranian patients.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Defibrillators, Implantable; Electric Stimulatio

2005
[Formation of a bundle branch block with flecainide].
    Deutsche medizinische Wochenschrift (1946), 1983, Jul-01, Volume: 108, Issue:26

    Topics: Bundle-Branch Block; Electrocardiography; Flecainide; Humans; Piperidines

1983
[Flecainide exercise induced left bundle branch with chest pain].
    Archives des maladies du coeur et des vaisseaux, 1994, Volume: 87, Issue:1

    Topics: Aged; Angina Pectoris; Atrial Fibrillation; Bundle-Branch Block; Coronary Angiography; Exercise; Fem

1994
His-Purkinje system reentry as a proarrhythmic effect of flecainide.
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:4 Pt 1

    Topics: Administration, Oral; Aged; Ajmaline; Anti-Arrhythmia Agents; Bundle of His; Bundle-Branch Block; El

2000
Spatial and temporal heterogeneity of depolarization and repolarization may complicate implantable cardioverter defibrillator therapy in Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2000, Volume: 11, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Ajmaline; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Paci

2000
Pseudo infarction ECG pattern occurring during intravenous treatment with flecainide acetate.
    European heart journal, 1992, Volume: 13, Issue:1

    Topics: Aged; Atrial Flutter; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Humans; Infusion

1992
Surgical ablation for idiopathic ventricular tachycardia.
    The Annals of thoracic surgery, 1990, Volume: 49, Issue:2

    Topics: Adult; Bundle-Branch Block; Cryosurgery; Fibrosis; Flecainide; Humans; Hypertrophy; Male; Papillary

1990
Acute flecainide toxicity.
    Chinese medical journal, 1990, Volume: 103, Issue:7

    Topics: Aged; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Humans

1990
Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment.
    The American journal of cardiology, 1988, Dec-01, Volume: 62, Issue:17

    Topics: Aged; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Tachy

1988