flecainide and Ache
flecainide has been researched along with Ache in 4 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a general population of patients with a working diagnosis of neuropathic pain, whether if flecainide produces enough of an improvement in pain to warrant further clinical study is determined." | 9.12 | Flecainide for the treatment of chronic neuropathic pain: a Phase II trial. ( Cella, D; Cleary, JF; Cleeland, C; Eappen, S; Moots, P; Regevik, N; Taylor, SG; von Gunten, CF, 2007) |
| "Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in paranoid psychosis." | 7.69 | Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain. ( Bennett, MI, 1997) |
| "In a general population of patients with a working diagnosis of neuropathic pain, whether if flecainide produces enough of an improvement in pain to warrant further clinical study is determined." | 5.12 | Flecainide for the treatment of chronic neuropathic pain: a Phase II trial. ( Cella, D; Cleary, JF; Cleeland, C; Eappen, S; Moots, P; Regevik, N; Taylor, SG; von Gunten, CF, 2007) |
| "Lidocaine and oral analogs were safe drugs in controlled clinical trials for neuropathic pain, were better than placebo, and were as effective as other analgesics." | 4.82 | Systemic administration of local anesthetic agents to relieve neuropathic pain. ( Carr, DB; Challapalli, V; Lau, J; McNicol, ED; Tremont-Lukats, IW, 2005) |
| "Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in paranoid psychosis." | 3.69 | Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain. ( Bennett, MI, 1997) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Challapalli, V | 1 |
| Tremont-Lukats, IW | 1 |
| McNicol, ED | 1 |
| Lau, J | 1 |
| Carr, DB | 1 |
| von Gunten, CF | 1 |
| Eappen, S | 1 |
| Cleary, JF | 1 |
| Taylor, SG | 1 |
| Moots, P | 1 |
| Regevik, N | 1 |
| Cleeland, C | 1 |
| Cella, D | 1 |
| Bennett, MI | 1 |
| Dunlop, R | 1 |
| Davies, RJ | 1 |
| Hockley, J | 1 |
| Turner, P | 1 |
Clinical Trials (3)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study[NCT02217267] | Phase 3 | 29 participants (Actual) | Interventional | 2014-08-01 | Completed | ||
| The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| Flecainide for the Treatment of Chronic Neuropathic Pain: A Phase II Trial[NCT00002996] | Phase 2 | 20 participants (Anticipated) | Interventional | 1998-05-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for flecainide and Ache
| Article | Year |
|---|---|
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Trials
1 trial available for flecainide and Ache
| Article | Year |
|---|---|
Flecainide for the treatment of chronic neuropathic pain: a Phase II trial.
Topics: Adult; Aged; Analgesics; Female; Flecainide; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Pain; | 2007 |
Other Studies
2 other studies available for flecainide and Ache
| Article | Year |
|---|---|
Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain.
Topics: Anti-Arrhythmia Agents; Brachial Plexus; Flecainide; Humans; Male; Middle Aged; Pain; Palliative Car | 1997 |
Analgesic effects of oral flecainide.
Topics: Administration, Oral; Flecainide; Humans; Nervous System Diseases; Pain | 1988 |