flecainide has been researched along with A-V Dissociation in 25 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of flecainide were studied in the maintenance of sinus rhythm after electrical cardioversion for chronic atrial fibrillation or atrial flutter." | 9.06 | Efficacy and safety of flecainide acetate in the maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation or atrial flutter. ( Crijns, HJ; Hamer, HP; Lie, KI; Van Gelder, IC; Van Gilst, WH; Van Wijk, LM, 1989) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 8.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Flecainide can "organise" atrial fibrillation into atrial flutter with 1:1 conduction, leading to cardiovascular compromise." | 7.76 | Tachycardia due to atrial flutter with rapid 1:1 conduction following treatment of atrial fibrillation with flecainide. ( Gandhi, MM; Lloyd, G; Taylor, R, 2010) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 7.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| " We describe the case of a 62-year-old male with latent Brugada syndrome in whom the intravenous infusion of flecainide for paroxysmal atrial fibrillation caused ECG abnormalities similar to those of an acute septal myocardial infarction." | 7.72 | [Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct]. ( Carotenuto, F; Cirillo, R; D'Errico, L; di Palma, F; Fontana, D; Granato, L; Pagano, V; Sestri, C; Vitiello, N, 2003) |
| "A 65-year-old man with paroxysmal atrial flutter was treated with digoxin and flecainide." | 7.68 | 1:1 atrioventricular conduction in atrial flutter with digoxin and flecainide. ( Ahsan, A; Aldridge, R; Bowes, R, 1993) |
| "The efficacy and safety of flecainide were studied in the maintenance of sinus rhythm after electrical cardioversion for chronic atrial fibrillation or atrial flutter." | 5.06 | Efficacy and safety of flecainide acetate in the maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation or atrial flutter. ( Crijns, HJ; Hamer, HP; Lie, KI; Van Gelder, IC; Van Gilst, WH; Van Wijk, LM, 1989) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 4.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Flecainide can "organise" atrial fibrillation into atrial flutter with 1:1 conduction, leading to cardiovascular compromise." | 3.76 | Tachycardia due to atrial flutter with rapid 1:1 conduction following treatment of atrial fibrillation with flecainide. ( Gandhi, MM; Lloyd, G; Taylor, R, 2010) |
| "The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients." | 3.72 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. ( Aliot, E; Capucci, A; Coumel, P; De Roy, L; Denjoy, I; Hernández, J; Lupoglazoff, JM, 2003) |
| " We describe the case of a 62-year-old male with latent Brugada syndrome in whom the intravenous infusion of flecainide for paroxysmal atrial fibrillation caused ECG abnormalities similar to those of an acute septal myocardial infarction." | 3.72 | [Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct]. ( Carotenuto, F; Cirillo, R; D'Errico, L; di Palma, F; Fontana, D; Granato, L; Pagano, V; Sestri, C; Vitiello, N, 2003) |
| "A 65-year-old man with paroxysmal atrial flutter was treated with digoxin and flecainide." | 3.68 | 1:1 atrioventricular conduction in atrial flutter with digoxin and flecainide. ( Ahsan, A; Aldridge, R; Bowes, R, 1993) |
| "Flecainide acetate is a Vaughan-Williams class IC antiarrhythmic drug prescribed for the treatment of supraventricular arrhythmias." | 1.56 | Complete Heart Block Secondary to Flecainide Toxicity: Is It Time for CYP2D6 Genotype Testing? ( Abdul Haium, AA; Choo, TLJ; Lee, JH; Poh, BH, 2020) |
| "Flecainide acetate is a potent class Ic anti-arrhythmic drug with major sodium channel blocking actions." | 1.30 | Survival in a case of life-threatening flecainide overdose. ( Bourke, JP; Gascoigne, AD; Hanley, NA, 1998) |
| "Complete heart block was produced in dogs using an 8 French hexapolar ablation catheter, anterior skin electrode, and radiofrequency current (30 W, 13." | 1.28 | A simple in vivo model to evaluate the effects of antiarrhythmic agents. ( Barbey, JT; Solomon, AJ; Syn, D, 1992) |
| "Flecainide acetate is a new potent class I antiarrhythmic agent." | 1.28 | The electrocardiographic changes in a case of flecainide overdose. ( Chung, PK; Tuso, P, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bardien-Kruger, S | 1 |
| Wulff, H | 1 |
| Arieff, Z | 1 |
| Brink, P | 1 |
| Chandy, KG | 1 |
| Corfield, V | 1 |
| Poh, BH | 1 |
| Lee, JH | 1 |
| Abdul Haium, AA | 1 |
| Choo, TLJ | 1 |
| Ferrante, JA | 1 |
| Rizvi, M | 1 |
| Sakaan, S | 1 |
| Eick, J | 1 |
| Cutshall, BT | 1 |
| Lloyd, T | 1 |
| Zimmerman, J | 1 |
| Griffin, GD | 1 |
| Taylor, R | 1 |
| Gandhi, MM | 1 |
| Lloyd, G | 1 |
| Aliot, E | 1 |
| De Roy, L | 1 |
| Capucci, A | 1 |
| Hernández, J | 1 |
| Denjoy, I | 1 |
| Lupoglazoff, JM | 1 |
| Coumel, P | 1 |
| Vitiello, N | 1 |
| Cirillo, R | 1 |
| Fontana, D | 1 |
| Granato, L | 1 |
| Sestri, C | 1 |
| Pagano, V | 1 |
| D'Errico, L | 1 |
| Carotenuto, F | 1 |
| di Palma, F | 1 |
| Lafuente Gormaz, C | 1 |
| Gallego Page, JC | 1 |
| Llamas Fuentes, F | 1 |
| Füessl, HS | 1 |
| Hellestrand, KJ | 1 |
| Burnett, PJ | 1 |
| Milne, JR | 1 |
| Bexton, RS | 1 |
| Nathan, AW | 1 |
| Camm, AJ | 3 |
| Ranger, S | 1 |
| Nattel, S | 1 |
| Windle, JR | 1 |
| Witt, RC | 1 |
| Rozanski, GJ | 1 |
| Ahsan, A | 1 |
| Aldridge, R | 1 |
| Bowes, R | 1 |
| Hanley, NA | 1 |
| Bourke, JP | 1 |
| Gascoigne, AD | 1 |
| Meurin, P | 1 |
| Larrazet, F | 1 |
| Weber, H | 1 |
| Bourmayan, C | 1 |
| Debbas, NM | 1 |
| Jackson, SH | 1 |
| de Jonghe, D | 1 |
| Robert, A | 1 |
| Maury, P | 1 |
| Vuille, C | 1 |
| Metzger, J | 1 |
| Veragut, B | 1 |
| Schoenenberger, I | 1 |
| Elamly, A | 1 |
| Chevrolet, JC | 1 |
| Solomon, AJ | 1 |
| Syn, D | 1 |
| Barbey, JT | 1 |
| Weissenburger, J | 1 |
| Davy, JM | 1 |
| Chézalviel, F | 1 |
| Ertzbischoff, O | 1 |
| Poirier, JM | 1 |
| Engel, F | 1 |
| Lainée, P | 1 |
| Penin, E | 1 |
| Motté, G | 1 |
| Cheymol, G | 1 |
| Zeigler, VL | 1 |
| Peterson, J | 1 |
| Chung, PK | 1 |
| Tuso, P | 1 |
| Finzi, A | 1 |
| Potenza, S | 1 |
| Guenzati, G | 1 |
| Van Gelder, IC | 1 |
| Crijns, HJ | 1 |
| Van Gilst, WH | 1 |
| Van Wijk, LM | 1 |
| Hamer, HP | 1 |
| Lie, KI | 1 |
| Lau, CP | 1 |
| Griffith, MJ | 1 |
| Brembilla-Perrot, B | 1 |
| Admant, P | 1 |
| Le Helloco, A | 1 |
| Pernot, C | 1 |
1 review available for flecainide and A-V Dissociation
| Article | Year |
|---|---|
[Severe flecainide acetate poisoning. Apropos of a case].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate | 1999 |
1 trial available for flecainide and A-V Dissociation
| Article | Year |
|---|---|
Efficacy and safety of flecainide acetate in the maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation or atrial flutter.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutte | 1989 |
23 other studies available for flecainide and A-V Dissociation
| Article | Year |
|---|---|
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart | 2002 |
Complete Heart Block Secondary to Flecainide Toxicity: Is It Time for CYP2D6 Genotype Testing?
Topics: Cytochrome P-450 CYP2D6; Electrocardiography; Flecainide; Genotype; Heart Block; Humans; Infant, New | 2020 |
Consequences of AV blockade omission in flecainide therapy.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Flecainide; Heart Block; Humans | 2021 |
Irreversible third-degree heart block and pacemaker implant in a case of flecainide toxicity.
Topics: Aged, 80 and over; Drug Overdose; Electrocardiography; Emergency Service, Hospital; Female; Flecaini | 2013 |
Tachycardia due to atrial flutter with rapid 1:1 conduction following treatment of atrial fibrillation with flecainide.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Female; Flecainide; Heart Block; Humans | 2010 |
Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Delayed-Ac | 2003 |
[Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Death, Sudden, Cardiac; Echocardiography; Electrocardio | 2003 |
[Pharmacological interaction between flecainide and benziodarone].
Topics: Aged; Anti-Arrhythmia Agents; Benzofurans; Drug Interactions; Female; Flecainide; Heart Block; Human | 2003 |
[Reason for worry: syncope in the morning].
Topics: Anti-Arrhythmia Agents; Circadian Rhythm; Death, Sudden, Cardiac; Diagnosis, Differential; Electroca | 2005 |
Effect of the antiarrhythmic agent flecainide acetate on acute and chronic pacing thresholds.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Dose-Res | 1983 |
Determinants and mechanisms of flecainide-induced promotion of ventricular tachycardia in anesthetized dogs.
Topics: Animals; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Fl | 1995 |
Effects of flecainide on ectopic atrial automaticity and conduction.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Electrophysiology; Flecainide; Heart Atria; Heart | 1993 |
1:1 atrioventricular conduction in atrial flutter with digoxin and flecainide.
Topics: Aged; Amiodarone; Atrial Flutter; Atrioventricular Node; Digoxin; Drug Therapy, Combination; Electro | 1993 |
Survival in a case of life-threatening flecainide overdose.
Topics: Adolescent; Anti-Arrhythmia Agents; Bradycardia; Creatine Kinase; Drug Overdose; Electrocardiography | 1998 |
[Iatrogenic acute renal failure caused by overdosage of flecainide acetate].
Topics: Acute Kidney Injury; Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-In | 1998 |
Human atrial repolarization: effects of sinus rate, pacing and drugs on the surface electrocardiogram.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atropine; Cardiac Pacing, Artificial; Disopy | 1999 |
A simple in vivo model to evaluate the effects of antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Cardiac Pacing, Artificial; Catheter Ablatio | 1992 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, A | 1991 |
Flecainide toxicity in a neonate with supraventricular tachycardia.
Topics: Electrocardiography; Flecainide; Heart Block; Humans; Infant, Newborn; Male; Tachycardia, Supraventr | 1991 |
The electrocardiographic changes in a case of flecainide overdose.
Topics: Adult; Drug Overdose; Electrocardiography; Female; Flecainide; Heart Block; Humans | 1990 |
[His bundle block 2:1 during paroxysmal supraventricular tachycardia involving an occult accessory atrio-His pathway].
Topics: Bundle of His; Electrocardiography; Female; Flecainide; Heart Block; Heart Conduction System; Humans | 1990 |
Ventricular Wenckebach after intravenous therapy with class I antiarrhythmic agents.
Topics: Adult; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Female; Flecainide; Heart Block; | 1988 |
Loss of efficacy of flecainide in the Wolff-Parkinson-White syndrome after isoproterenol administration.
Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Heart Block; Heart Conductio | 1985 |