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flavoxate and Urinary Incontinence

flavoxate has been researched along with Urinary Incontinence in 17 studies

Flavoxate: A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist.
flavoxate : A carboxylic ester resulting from the formal condensation of 3-methylflavone-8-carboxylic acid with 2-(1-piperidinyl)ethanol.

Urinary Incontinence: Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.

Research Excerpts

ExcerptRelevanceReference
"The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence."7.66The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly. ( Asher, MJ; Briggs, RS; Castleden, CM, 1980)
" A comparison of flavoxate, emepronium, propantheline and a placebo for the treatment of urinary incontinence due to bladder instability is made, the results are discussed and recommendations are made."5.05Motor urge incontinence: diagnosis and treatment. ( Gaudenz, R; Weil, A, 1980)
" She had been undergoing treatment with flavoxate for urinary incontinence (for 2 months before admission) and with tibolone for climacteric syndrome (for 6 months before admission)."3.74Drug-induced acute cholestatic liver damage in a patient with mutation of UGT1A1. ( Avellini, C; Cravatari, M; Crocè, SL; Ponte, E; Rigato, I; Tiribelli, C, 2007)
" Furthermore, NS-21 increased the bladder capacity without suppressing micturition pressure, suggesting that NS-21 may be a more effective therapeutic drug than propiverine, oxybutynin or flavoxate for the treatment of urinary frequency and urinary incontinence."3.69Effect of NS-21, an anticholinergic drug with calcium antagonistic activity, on lower urinary tract function in a rat model of urinary frequency. ( Hamada, K; Kimura, K; Kimura, Y; Sasaki, Y; Seto, T; Ukai, Y; Yamazaki, C; Yoshikuni, Y, 1997)
"The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence."3.66The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly. ( Asher, MJ; Briggs, RS; Castleden, CM, 1980)
" The application period was 4 weeks and the dosage was 45 mg/d Mictonorm and 300 mg/d Spasuret, respectively."2.66[Comparative studies of the effect of mictonorm (propiverin hydrochloride) and Spasuret (flavoxate hydrochloride) on the bladder detrusor muscle]. ( Sage, S; Wehnert, J, 1989)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's3 (17.65)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohammed, ZS1
Simi, ZU1
Tariq, SM1
Ali, KR1
Rigato, I1
Cravatari, M1
Avellini, C1
Ponte, E1
Crocè, SL1
Tiribelli, C1
Meyhoff, HH1
Gerstenberg, TC1
Nordling, J1
Robinson, JM1
Brocklehurst, JC1
Grüneberger, A1
Briel, RC1
Gassner, K1
Jarvis, GJ1
Madersbacher, H1
Gaudenz, R2
Weil, A1
Briggs, RS1
Castleden, CM1
Asher, MJ1
Sasaki, Y1
Hamada, K1
Yamazaki, C1
Seto, T1
Kimura, Y1
Ukai, Y1
Yoshikuni, Y1
Kimura, K1
Fehrmann-Zumpe, P1
Karbe, K1
Blessman, G1
Milroy, E1
Adam, PJ1
von Fischer, B1
Dreher, E1
Wehnert, J1
Sage, S1

Reviews

1 review available for flavoxate and Urinary Incontinence

ArticleYear
[Drug therapy of urinary incontinence in women].
    Medizinische Monatsschrift fur Pharmazeuten, 1993, Volume: 16, Issue:10

    Topics: Adult; Aged; Emepronium; Estrogen Replacement Therapy; Female; Flavoxate; Humans; Middle Aged; Paras

1993

Trials

8 trials available for flavoxate and Urinary Incontinence

ArticleYear
Placebo--the drug of choice in female motor urge incontinence?
    British journal of urology, 1983, Volume: 55, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Emepronium; Female; Flavoxate; Humans; M

1983
Emepronium bromide and flavoxate hydrochloride in the treatment of urinary incontinence associated with detrusor instability in elderly women.
    British journal of urology, 1983, Volume: 55, Issue:4

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Emepronium; Female;

1983
Treatment of motor urge incontinence with clenbuterol and flavoxate hydrochloride.
    British journal of obstetrics and gynaecology, 1984, Volume: 91, Issue:3

    Topics: Clenbuterol; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Flavonoids; Flavo

1984
[First experience with flavoxat in bladder - conditioned types of incontinence in gynaecology (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1980, Volume: 40, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Flavonoids; Flavoxate; Humans; Manometry; Middle Aged

1980
A controlled trial of bladder drill and drug therapy in the management of detrusor instability.
    British journal of urology, 1981, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Flavoxate; Humans; Imipramine; Middle Age

1981
Motor urge incontinence: diagnosis and treatment.
    Urologia internationalis, 1980, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Emepronium; Female; Flavoxate; Humans; Middle Aged; Parasympatholytics; Pro

1980
Using flavoxate as primary medication for patients suffering from urge symptomatology.
    International urogynecology journal and pelvic floor dysfunction, 1999, Volume: 10, Issue:2

    Topics: Adult; Aged; Drug Utilization; Female; Flavoxate; Humans; Male; Middle Aged; Parasympatholytics; Sur

1999
[Comparative studies of the effect of mictonorm (propiverin hydrochloride) and Spasuret (flavoxate hydrochloride) on the bladder detrusor muscle].
    Zeitschrift fur Urologie und Nephrologie, 1989, Volume: 82, Issue:5

    Topics: Benzilates; Clinical Trials as Topic; Flavonoids; Flavoxate; Humans; Middle Aged; Parasympatholytics

1989

Other Studies

8 other studies available for flavoxate and Urinary Incontinence

ArticleYear
Bilateral acute angle closure glaucoma in a 50 year old female after oral administration of flavoxate.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:5

    Topics: Acute Disease; Female; Flavoxate; Glaucoma, Angle-Closure; Humans; Middle Aged; Parasympatholytics;

2008
Drug-induced acute cholestatic liver damage in a patient with mutation of UGT1A1.
    Nature clinical practice. Gastroenterology & hepatology, 2007, Volume: 4, Issue:7

    Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Climacteric; Female; Flavoxate; Follow-Up Stu

2007
[Diagnosis of functional neurogenic urination disorders from the urologist's viewpoint].
    Gynakologische Rundschau, 1980, Volume: 20 Suppl 2

    Topics: Female; Flavoxate; Humans; Middle Aged; Muscle Contraction; Muscle Relaxation; Urethritis; Urinary B

1980
The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly.
    The Journal of urology, 1980, Volume: 123, Issue:5

    Topics: Aged; Dose-Response Relationship, Drug; Flavonoids; Flavoxate; Humans; Muscle Contraction; Urinary I

1980
Effect of NS-21, an anticholinergic drug with calcium antagonistic activity, on lower urinary tract function in a rat model of urinary frequency.
    International journal of urology : official journal of the Japanese Urological Association, 1997, Volume: 4, Issue:4

    Topics: Animals; Atropine; Benzilates; Calcium Channel Blockers; Denervation; Disease Models, Animal; Flavox

1997
Pharmacological management of common urodynamic problems.
    The Urologic clinics of North America, 1979, Volume: 6, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Antidepressive Agents, Tricyclic; Bromocriptine

1979
[Drug effect on motoric and sensory urge incontinence].
    Archives of gynecology, 1979, Jul-20, Volume: 228, Issue:1-4

    Topics: Adult; Aged; Emepronium; Female; Flavoxate; Humans; Middle Aged; Urinary Bladder, Neurogenic; Urinar

1979
Incontinence.
    British medical journal, 1978, Jan-14, Volume: 1, Issue:6105

    Topics: Disposable Equipment; Emepronium; Flavoxate; Habits; Humans; Urinary Catheterization; Urinary Incont

1978