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flavone acetic acid and Experimental Neoplasms

flavone acetic acid has been researched along with Experimental Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199011 (40.74)18.7374
1990's16 (59.26)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaplin, DJ; Griffiths, JR; McCoy, CL; Parkins, CS; Rodrigues, LM; Stubbs, M1
Chaplin, DJ; Hill, SA; Sampson, LE1
Crom, WR; Evans, RR; Groom, S; Pratt, CB; Relling, MV1
Chaplin, DJ; Hill, SA; Parkins, CS; Pettit, GR1
Begent, RH; Boden, JA; Boden, R; Boxer, GM; Flynn, AA; Keep, PA; Pedley, RB1
Aitken, RA; Bibby, MC; Bielefeldt, F; Double, JA; Laws, AL; Mathieu, AL; Ritchie, RB; Wilson, DW1
Nalcioglu, O; Su, MY; Wang, Z1
Baguley, BC; Gavin, JB; Holdaway, KM; Wilson, WR; Zwi, LJ1
Baguley, BC; Ching, LM; Gavin, JB; Joseph, WR; Thomsen, LL1
Moore, JV; West, DC1
Denekamp, J; Hill, SA; Williams, KB1
Murray, JC; Smith, KA; Stern, DM1
Denekamp, J; Hill, S1
Parmiani, G; Pratesi, G; Rodolfo, M; Rovetta, G1
Braida, A; Caruso, G; D'Incalci, M; Damia, G; Freschi, A; Monfardini, S; Quaia, M; Sorio, R1
Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ2
Denekamp, J; Hill, S; Williams, KB1
Bibby, MC; Cummings, J; Double, JA; Evans, S; Farmer, P; Kaye, SB; Kerr, DJ; Smyth, JF1
Brown, JM; Sun, JR1
Murray, JC; Smith, KA; Thurston, G1
Bibby, MC; Double, JA; Duke, CV; Loadman, PM1
Baguley, BC; Ching, LM1
Baguley, BC; Finlay, GJ; Fray, LM; Smith, GP1
Corbett, T; Cradock, J; Grieshaber, C; Hoth, DF; King, SA; O'Dwyer, PJ; Plowman, J; Shoemaker, D; Valeriote, F; Zaharko, DS1
Bissery, MC; Corbett, TH; Dieckman, J; Plowman, J; Polin, L; Tapazoglou, E; Valeriote, F; Wozniak, A1
Cradock, JC; Grieshaber, CK; Plowman, J; Zaharko, DS1

Reviews

2 review(s) available for flavone acetic acid and Experimental Neoplasms

ArticleYear
Angiogenic attack as a therapeutic strategy for cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1

    Topics: Animals; Cell Survival; Flavonoids; Hyperthermia, Induced; Immunologic Factors; Mice; Neoplasms, Experimental; Radiation-Sensitizing Agents; Regional Blood Flow

1991
Flavone acetic acid (LM 975, NSC 347512). A novel antitumor agent.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Flavonoids; Humans; Kinetics; Mice; Neoplasms, Experimental; Rats; Structure-Activity Relationship

1987

Trials

1 trial(s) available for flavone acetic acid and Experimental Neoplasms

ArticleYear
Saturable elimination and saturable protein binding account for flavone acetic acid pharmacokinetics.
    Journal of pharmacokinetics and biopharmaceutics, 1993, Volume: 21, Issue:6

    Topics: Antineoplastic Agents; Child; Flavonoids; Humans; Kinetics; Neoplasms; Neoplasms, Experimental; Protein Binding

1993

Other Studies

24 other study(ies) available for flavone acetic acid and Experimental Neoplasms

ArticleYear
The effect of blood flow modification on intra- and extracellular pH measured by 31P magnetic resonance spectroscopy in murine tumours.
    British journal of cancer, 1995, Volume: 72, Issue:4

    Topics: Adenosine Triphosphate; Animals; Flavonoids; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Regional Blood Flow

1995
Anti-vascular approaches to solid tumour therapy: evaluation of vinblastine and flavone acetic acid.
    International journal of cancer, 1995, Sep-27, Volume: 63, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Flavonoids; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Regional Blood Flow; Vinblastine

1995
Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Animals; Antineoplastic Agents; Bibenzyls; Depsipeptides; Flavonoids; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Oligopeptides; Regional Blood Flow; Stilbenes; Tirapazamine; Triazines; Tubulin; Tumor Necrosis Factor-alpha; Vinblastine

1996
Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents.
    Cancer research, 1996, Jul-15, Volume: 56, Issue:14

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Carcinoembryonic Antigen; Colorectal Neoplasms; Combined Modality Therapy; Flavonoids; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radioimmunotherapy; Regional Blood Flow; Serotonin; Tissue Distribution; Transplantation, Heterologous; Xanthenes; Xanthones

1996
Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 3: 2-Heteroaryl derivatives.
    Archiv der Pharmazie, 1998, Volume: 331, Issue:12

    Topics: Animals; Antineoplastic Agents; Flavonoids; Heterocyclic Compounds; Humans; Mice; Molecular Structure; Neoplasms, Experimental; Tumor Cells, Cultured

1998
Investigation of longitudinal vascular changes in control and chemotherapy-treated tumors to serve as therapeutic efficacy predictors.
    Journal of magnetic resonance imaging : JMRI, 1999, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Capillary Permeability; Contrast Media; Female; Flavonoids; Gadolinium DTPA; Magnetic Resonance Imaging; Mitomycin; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sensitivity and Specificity; Time Factors

1999
The role of immune effector cells in flavone acetic acid-induced injury to tumor cells in EMT6 spheroids.
    Oncology research, 1992, Volume: 4, Issue:8-9

    Topics: Animals; Antineoplastic Agents; Cytotoxicity, Immunologic; Dexamethasone; Flavonoids; Mice; Mice, Inbred BALB C; Necrosis; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneal Cavity; Tumor Cells, Cultured

1992
Nitric oxide production in endotoxin-resistant C3H/HeJ mice stimulated with flavone-8-acetic acid and xanthenone-4-acetic acid analogues.
    Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11

    Topics: Animals; Cells, Cultured; Drug Resistance; Endotoxins; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitrates; Nitric Oxide; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes

1992
Vasculature as a target for anti-cancer therapy.
    Cancer cells (Cold Spring Harbor, N.Y. : 1989), 1991, Volume: 3, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Blood Coagulation; Endothelium, Vascular; Flavonoids; Humans; Hyperthermia, Induced; Immunologic Factors; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Photochemotherapy; Regional Blood Flow

1991
A comparison of vascular-mediated tumor cell death by the necrotizing agents GR63178 and flavone acetic acid.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Death; Flavonoids; Injections, Intraperitoneal; Isoquinolines; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds

1992
Flavone acetic acid potentiates the induction of endothelial procoagulant activity by tumour necrosis factor.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, Northern; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Flavonoids; Humans; Male; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Thromboplastin; Tumor Necrosis Factor-alpha

1991
Role of T cells and tumour necrosis factor in antitumour activity and toxicity of flavone acetic acid.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:10

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Flavonoids; Killer Cells, Natural; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; T-Lymphocytes; Tumor Necrosis Factor-alpha

1990
Flavone acetic acid distribution in human malignant tumors.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Drug Evaluation; Female; Flavonoids; Humans; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Species Specificity; Tissue Distribution

1990
The use of vascularised spheroids to investigate the action of flavone acetic acid on tumour blood vessels.
    British journal of cancer, 1990, Volume: 62, Issue:2

    Topics: Acridine Orange; Animals; Antineoplastic Agents; Blood Vessels; Flavonoids; Fluorescence; Injections, Intraperitoneal; Injections, Intravenous; Mice; Neoplasm Transplantation; Neoplasms, Experimental

1990
Vascular collapse after flavone acetic acid: a possible mechanism of its anti-tumour action.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:10

    Topics: Animals; Antineoplastic Agents; Female; Flavonoids; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Regional Blood Flow

1989
Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice.
    Cancer research, 1989, Jul-01, Volume: 49, Issue:13

    Topics: Animals; Antineoplastic Agents; Biotransformation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flavonoids; Humans; Mice; Neoplasms, Experimental; Species Specificity; Tissue Distribution

1989
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.
    Journal of the National Cancer Institute, 1989, Jul-05, Volume: 81, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Survival; Flavonoids; Ischemia; Mice; Neoplasms, Experimental; Organoids; Regional Blood Flow; Time Factors; Tumor Cells, Cultured

1989
Enhancement of the antitumor effect of flavone acetic acid by the bioreductive cytotoxic drug SR 4233 in a murine carcinoma.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Lethal Dose 50; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Oxidation-Reduction; Regional Blood Flow; Tirapazamine; Triazines

1989
Flavone acetic acid induces a coagulopathy in mice.
    British journal of cancer, 1989, Volume: 60, Issue:5

    Topics: Animals; Antineoplastic Agents; Blood Coagulation; Fibrin Fibrinogen Degradation Products; Flavonoids; Male; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Platelet Count; Prothrombin Time; Thrombin Time

1989
Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.
    Journal of the National Cancer Institute, 1989, Feb-01, Volume: 81, Issue:3

    Topics: Adenocarcinoma; Animals; Flavonoids; Mice; Neoplasms, Experimental; Regional Blood Flow

1989
Enhancement of in vitro cytotoxicity of mouse peritoneal exudate cells by flavone acetic acid (NSC 347512).
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:9

    Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Cell Line; Cytotoxicity, Immunologic; Dexamethasone; Flavonoids; Macrophages; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Stimulation, Chemical; Time Factors; Tumor Cells, Cultured

1988
Effect of flavone acetic acid on Lewis lung carcinoma: evidence for an indirect effect.
    Journal of the National Cancer Institute, 1988, Apr-20, Volume: 80, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Survival; Flavonoids; Humans; Leukemia P388; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Tumor Cells, Cultured

1988
Activity of flavone acetic acid (NSC-347512) against solid tumors of mice.
    Investigational new drugs, 1986, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Flavonoids; Lymphoma, Large B-Cell, Diffuse; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Pancreatic Neoplasms

1986
Therapeutic and pharmacokinetic relationships of flavone acetic acid: an agent with activity against solid tumors.
    Cancer treatment reports, 1986, Volume: 70, Issue:12

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Flavonoids; Kinetics; Mice; Neoplasms, Experimental

1986