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flavone acetic acid and Colonic Neoplasms

flavone acetic acid has been researched along with Colonic Neoplasms in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199016 (45.71)18.7374
1990's19 (54.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwell, GJ; Baguley, BC; Denny, WA; Li, ZA; Rewcastle, GW1
Atwell, GJ; Baguley, BC; Calveley, SB; Denny, WA; Rewcastle, GW1
Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ2
Begent, RH; Boden, JA; Boden, R; Boxer, GM; Keep, PA; Pedley, RB1
Baguley, BC; Cole, G; Li, Z; Thomsen, LL1
Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E1
Baguley, BC; Kestell, P; Zhuang, L1
Aitken, RA; Bibby, MC; Double, JA; Laws, AL; Ritchie, RB; Wilson, DW1
Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL1
Back, TT; Baguley, BC; Eader, L; Futami, H; Gruys, E; Wiltrout, RH; Young, HA1
Baguley, BC; Ching, LM; Joseph, WR1
Hart, IR; Mahadevan, V1
Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL; Zhuang, L1
Bibby, MC; Double, JA; Phillips, RM; Pratesi, G1
Bibby, MC; Double, JA; Phillips, RM2
Baguley, BC; Ching, LM; Thomsen, LL1
Bernabei, A; Corbett, TH; Freedland, C; Luk, GD; Neelam, SS; Thompson, R1
Atwell, GJ; Baguley, BC; Denny, WA; Rewcastle, GW2
Fiers, W; Hart, IR; Lewis, GP; Mahadevan, V; Malik, ST; Meager, A1
Baker, LH; Bissery, MC; Chabot, GG; Corbett, TH; Rutkowski, K1
Baguley, BC; Ching, LM1
Baguley, BC; Calveley, SB; Crowe, KK; Fray, LM; O'Rourke, SA; Smith, GP1
Bissery, MC; Chabot, GG; Gouyette, A1
D'Incalci, M; Damia, G; Manzotti, C; Pratesi, G1
Bibby, MC; Double, JA; Gummer, JA; Loadman, PM; Phillips, RM1
Bibby, MC; Double, JA; Loadman, PM1
Bissery, MC; Corbett, TH; Dieckman, J; Plowman, J; Polin, L; Tapazoglou, E; Valeriote, F; Wozniak, A1
Drewinko, B; Yang, LY1
Delforge, AR; Dethier, NE; Dodion, PF; Kenis, Y; Loos, M; Sanders, C; Schroyens, WA; Stryckmans, PA1
Baguley, BC; Calveley, SB; Smith, GP; Smith, MJ1
Briet, P; Dykes, D; Narayanan, VL; Paull, KD; Plowman, J; Szarvasi, E; Yoder, OC1
Bibby, MC; Double, JA; Loadman, PM; Phillips, RM1

Other Studies

35 other study(ies) available for flavone acetic acid and Colonic Neoplasms

ArticleYear
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Indicators and Reagents; Mice; Mice, Inbred Strains; Molecular Structure; Structure-Activity Relationship; Xanthenes; Xanthones

1991
Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Acetates; Adenocarcinoma; Animals; Chemical Phenomena; Chemistry; Chlorine; Colonic Neoplasms; Hydroxylation; Methylation; Mice; Nitro Compounds; Structure-Activity Relationship; Xanthenes

1989
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
    Oncology research, 1994, Volume: 6, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Flavonoids; Immunity, Cellular; Male; Mice; Mice, Inbred Strains; Necrosis; Structure-Activity Relationship; Tumor Cells, Cultured; Xanthenes

1994
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
    Pathology, 1994, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones

1994
Enhancement of radioimmunotherapy by drugs modifying tumour blood flow in a colonic xenograft model.
    International journal of cancer, 1994, Jun-15, Volume: 57, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Colonic Neoplasms; Female; Flavonoids; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Regional Blood Flow; Tissue Distribution; Tumor Cells, Cultured

1994
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Nitrates; Nitric Oxide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

1993
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones

1993
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
    Oncology research, 1997, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones

1997
Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 2: Ring-substituted derivatives.
    Archiv der Pharmazie, 1997, Volume: 330, Issue:7

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Humans; Mice; Tumor Cells, Cultured

1997
Modulation of superoxide production from murine macrophages by the antitumour agent flavone acetic acid and xanthenone acetic acid analogues.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Necrosis; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthenes

1992
Cytokine induction and therapeutic synergy with interleukin-2 against murine renal and colon cancers by xanthenone-4-acetic acid derivatives.
    Journal of immunotherapy : official journal of the Society for Biological Therapy, 1992, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Cytokines; DNA; DNA Probes; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Gene Expression Regulation, Neoplastic; Interferon-alpha; Interferon-gamma; Interleukin-2; Kidney Neoplasms; Leukocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Recombinant Proteins; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Xanthenes

1992
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice.
    British journal of cancer, 1992, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; T-Lymphocytes; Thymectomy; Xanthenes; Xanthones

1992
Divergent effects of flavone acetic acid on established versus developing tumour blood flow.
    British journal of cancer, 1991, Volume: 63, Issue:6

    Topics: Animals; Biocompatible Materials; Colonic Neoplasms; Flavonoids; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Polyurethanes; Protamines; Regional Blood Flow

1991
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Methylation; Mice; Mice, Inbred Strains; Nitrates; Nitrites; Xanthenes; Xanthones

1991
Anti-tumour activity of flavone acetic acid (NSC 347512) in mice--influence of immune status.
    British journal of cancer, 1991, Volume: 63, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Humans; Immune System; Immunity; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Thymectomy; Transplantation, Heterologous

1991
The relationship between tissue levels of flavone acetic acid (NSC 347512) and site dependent anti-tumour activity in murine colon tumours.
    British journal of cancer, 1991, Volume: 63, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biological Availability; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; In Vitro Techniques; Mice; Microsomes, Liver; Neoplasm Transplantation; Phenobarbital; Tissue Distribution

1991
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Animals; Antineoplastic Agents; Arginine; Cell Survival; Colonic Neoplasms; Dexamethasone; Flavonoids; Macrophages; Mice; Neoplasm Transplantation; Nitrates; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Xanthenes

1990
Combination of flavone acetic acid (FAA) with adriamycin, cis-platinum and difluoromethylornithine (DFMO) in vitro against human colon cancer cells.
    Investigational new drugs, 1990, Volume: 8, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Eflornithine; Flavonoids; Humans; Tumor Cells, Cultured

1990
Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:5

    Topics: Acetates; Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Flavonoids; Mice; Structure-Activity Relationship; Xanthenes

1990
Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Flavonoids; Immune Sera; Male; Mice; Mice, Inbred BALB C; Recombinant Proteins; Regional Blood Flow; Tumor Necrosis Factor-alpha; Xenon Radioisotopes

1990
Pharmacodynamics and causes of dose-dependent pharmacokinetics of flavone-8-acetic acid (LM-975; NSC-347512) in mice.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bile; Blood Proteins; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dose-Response Relationship, Drug; Feces; Flavonoids; Gastric Mucosa; Glucuronates; Intestinal Mucosa; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL

1989
Reduction of cytotoxic effector cell activity in colon 38 tumours following treatment with flavone acetic acid.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cytotoxicity Tests, Immunologic; Flavonoids; Killer Cells, Natural; Mice

1989
Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:2

    Topics: Alkaloids; Alkenes; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Harringtonines; Homoharringtonine; Mice; Mice, Inbred Strains; Polyenes; Pyrones; Tumor Necrosis Factor-alpha

1989
Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512).
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Humans; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Remission Induction; Skin Neoplasms; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Flavone acetic acid (LM-975; NSC-347512) activation to cytotoxic species in vivo and in vitro.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cells, Cultured; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Liver; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Phenobarbital; Prodrugs; Time Factors; Tumor Cells, Cultured

1989
Synthesis and anti-tumour activity of topologically-related analogues of flavoneacetic acid.
    Anti-cancer drug design, 1989, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation, Preclinical; Flavonoids; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Structure-Activity Relationship

1989
Response of chemically induced primary colon tumours of the mouse to flavone acetic acid (NSC 347 512).
    British journal of cancer, 1988, Volume: 58, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Female; Flavonoids; Fluorouracil; Kidney; Liver; Methylazoxymethanol Acetate; Mice; Spleen

1988
Experimental anti-tumor effects of flavone acetic acid (LM975).
    Progress in clinical and biological research, 1988, Volume: 280

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Flavonoids; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Tumor Stem Cell Assay

1988
Unique chemosensitivity of MAC 16 tumours to flavone acetic acid (LM975, NSC 347512).
    British journal of cancer, 1988, Volume: 58, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Weight Loss

1988
Activity of flavone acetic acid (NSC-347512) against solid tumors of mice.
    Investigational new drugs, 1986, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Flavonoids; Lymphoma, Large B-Cell, Diffuse; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Pancreatic Neoplasms

1986
The activity of flavone acetic acid (NSC 347512) on human colon cancer cells in vitro.
    Investigational new drugs, 1986, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Colonic Neoplasms; Flavonoids; Humans

1986
In vitro chemosensitivity testing of flavone acetic acid (LM975; NSC 347512) and its diethylaminoethyl ester derivative (LM985; NSC 293015).
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:8

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Colonic Neoplasms; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Head and Neck Neoplasms; Humans; Leukemia; Tumor Cells, Cultured

1987
Flavone acetic acid (NSC 347512) induces haemorrhagic necrosis of mouse colon 26 and 38 tumours.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:8

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Flavonoids; Hemorrhage; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Necrosis

1987
Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation, Preclinical; Flavonoids; Leukemia L1210; Leukemia P388; Mice

1986
Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid).
    British journal of cancer, 1987, Volume: 55, Issue:2

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Administration Schedule; Flavonoids; Mice; Mice, Inbred Strains; Neoplastic Stem Cells; Peritoneum

1987