fk 224 has been researched along with Asthma in 7 studies
*Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braun, A; Hoyle, GW; Lommatzsch, M; Quarcoo, D; Renz, H; Schierhorn, K; Schulte-Herbrüggen, O | 1 |
| Fujimura, M; Nakao, S; Nishitsuji, M; Oribe, Y | 1 |
| Joos, GF; Kips, JC; Pauwels, RA; Van Schoor, J | 1 |
| Jörres, RA; Magnussen, H; Rabe, KF; Schmidt, D | 1 |
| Fujimura, M; Ishiura, Y; Matsuda, T; Myou, S; Tsujiura, M | 1 |
| Ichinose, M; Inoue, H; Nakajima, N; Takahashi, T; Takishima, T; Yamauchi, H | 1 |
| Ezaki, M; Hashimoto, M; Hayashi, K; Imanaka, H; Kiyoto, S; Kohsaka, M; Nishikawa, M; Okuhara, M; Shigematsu, N; Yamashita, M | 1 |
3 trial(s) available for fk 224 and Asthma
| Article | Year |
|---|---|
The effect of inhaled FK224, a tachykinin NK-1 and NK-2 receptor antagonist, on neurokinin A-induced bronchoconstriction in asthmatics.
Topics: Administration, Inhalation; Asthma; Bronchoconstriction; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-2; Respiratory Function Tests | 1996 |
Reproducibility of airway response to inhaled bradykinin and effect of the neurokinin receptor antagonist FK-224 in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Analysis of Variance; Asthma; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Male; Peptides, Cyclic | 1996 |
Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist.
Topics: Administration, Inhalation; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Humans; Male; Middle Aged; Peptides, Cyclic; Placebos; Tachykinins | 1992 |
4 other study(ies) available for fk 224 and Asthma
| Article | Year |
|---|---|
Nerve growth factor induces increased airway inflammation via a neuropeptide-dependent mechanism in a transgenic animal model of allergic airway inflammation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Eosinophils; Humans; Interleukin-5; Leukocyte Count; Lung; Mice; Mice, Transgenic; Models, Animal; Nerve Growth Factors; Ovalbumin; Peptides, Cyclic; Receptors, Tachykinin; Tachykinins | 2004 |
A guinea pig model for cough variant asthma and role of tachykinins.
Topics: Airway Resistance; Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cough; Disease Models, Animal; Guinea Pigs; Male; Methacholine Chloride; Ovalbumin; Peptides, Cyclic; Procaterol; Tachykinins | 2004 |
Role of sensory neuropeptides in post-allergic propranolol-induced bronchoconstriction in guinea pigs in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dipeptides; Guinea Pigs; Indoles; Male; Neurokinin A; Peptides, Cyclic; Propranolol; Substance P | 1996 |
WS9326A, a novel tachykinin antagonist isolated from Streptomyces violaceusniger no. 9326. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
Topics: Animals; Asthma; Fermentation; Guinea Pigs; In Vitro Techniques; Lactones; Microscopy, Electron, Scanning; Peptides, Cyclic; Streptomyces; Substance P; Tachykinins | 1992 |