Page last updated: 2024-10-27

fipronil and Pregnancy

fipronil has been researched along with Pregnancy in 7 studies

fipronil: has low mammalian toxicity; structure given in first source
fipronil : A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile : A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Fipronil can cause thyroid dysfunction, which may affect brain growth and nerve development."1.56Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats. ( Chang, YN; Tsai, TH, 2020)
"Fipronil is a highly effective insecticide with extensive usages; however, its distribution and toxic/health effects in the human population after chronic exposure have not yet been clearly identified."1.51Distribution of fipronil in humans, and adverse health outcomes of in utero fipronil sulfone exposure in newborns. ( Cho, YH; Cole, E; Jeon, SJ; Kho, Y; Kim, HS; Kim, YA; Lee, J; Yoon, YS, 2019)
"Fipronil is an insecticide widely used in agriculture, veterinary medicine and public health that has recently been listed as a potential endocrine disrupter."1.46Perinatal exposure to insecticide fipronil: effects on the reproductive system in male rats. ( Anselmo-Franci, JA; Arena, AC; Bae, JH; Borges, CS; Cavariani, MM; de Barros, AL; Pinheiro, PFF; Rosa, JL; Silva, PV, 2017)
"Treatment with fipronil altered cyclicity of female rats lengthening the estrous cycle (days) after a single topic administration of 70 mg/kg (9."1.32Reproductive adverse effects of fipronil in Wistar rats. ( Andrade, AJ; Dalsenter, PR; Nascimento, AJ; Ohi, M, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Park, W1
Lim, W1
Song, G1
Chang, YN1
Tsai, TH1
Šefčíková, Z1
Babeľová, J1
Čikoš, Š1
Kovaříková, V1
Burkuš, J1
Špirková, A1
Koppel, J1
Fabian, D1
Kim, YA1
Yoon, YS1
Kim, HS1
Jeon, SJ1
Cole, E1
Lee, J1
Kho, Y1
Cho, YH1
de Barros, AL2
Rosa, JL2
Cavariani, MM2
Borges, CS2
Villela e Silva, P1
Bae, JH2
Anselmo-Franci, JA2
Cristina Arena, A1
Silva, PV1
Pinheiro, PFF1
Arena, AC1
Ohi, M1
Dalsenter, PR1
Andrade, AJ1
Nascimento, AJ1

Other Studies

7 other studies available for fipronil and Pregnancy

ArticleYear
Exposure to fipronil induces cell cycle arrest, DNA damage, and apoptosis in porcine trophectoderm and endometrial epithelium, leading to implantation defects during early pregnancy.
    Environmental pollution (Barking, Essex : 1987), 2021, Dec-15, Volume: 291

    Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; DNA Damage; Embryo Implantation; End

2021
Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10

    Topics: Administration, Oral; Amniotic Fluid; Animals; Biological Availability; Biotransformation; Dose-Resp

2020
Fipronil causes toxicity in mouse preimplantation embryos.
    Toxicology, 2018, 12-01, Volume: 410

    Topics: Animals; Apoptosis; Blastocyst; Cell Death; Dose-Response Relationship, Drug; Embryonic Development;

2018
Distribution of fipronil in humans, and adverse health outcomes of in utero fipronil sulfone exposure in newborns.
    International journal of hygiene and environmental health, 2019, Volume: 222, Issue:3

    Topics: Adult; Apgar Score; Biological Monitoring; Female; Fetal Blood; Humans; Infant, Newborn; Insecticide

2019
In utero and lactational exposure to fipronil in female rats: Pregnancy outcomes and sexual development.
    Journal of toxicology and environmental health. Part A, 2016, Volume: 79, Issue:6

    Topics: Animals; Estrus; Female; Fertility; Gonadal Steroid Hormones; Insecticides; Lactation; Male; Ovary;

2016
Perinatal exposure to insecticide fipronil: effects on the reproductive system in male rats.
    Reproduction, fertility, and development, 2017, Volume: 29, Issue:6

    Topics: Administration, Oral; Animals; Asthenozoospermia; Cell Shape; Dose-Response Relationship, Drug; Endo

2017
Reproductive adverse effects of fipronil in Wistar rats.
    Toxicology letters, 2004, Jan-15, Volume: 146, Issue:2

    Topics: Animals; Estradiol; Estrus; Female; Insecticides; Pregnancy; Pregnancy Outcome; Progesterone; Pyrazo

2004