Page last updated: 2024-10-27

fipronil and Ectoparasitic Infestations

fipronil has been researched along with Ectoparasitic Infestations in 35 studies

fipronil: has low mammalian toxicity; structure given in first source
fipronil : A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile : A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively.

Ectoparasitic Infestations: Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.

Research Excerpts

ExcerptRelevanceReference
"Two insecticides, fipronil and imidacloprid, were evaluated for efficacy and longevity against Oropsylla montana (Baker), the most important vector of plague in California."7.71Laboratory evaluation of fipronil and imidacloprid topical insecticides for control of the plague vector Oropsylla montana (Siphonaptera: Ceratophyllidae) on california ground squirrels (Rodentia: Sciuridae). ( Metzger, ME; Rust, MK, 2002)
"Two insecticides, fipronil and imidacloprid, were evaluated for efficacy and longevity against Oropsylla montana (Baker), the most important vector of plague in California."3.71Laboratory evaluation of fipronil and imidacloprid topical insecticides for control of the plague vector Oropsylla montana (Siphonaptera: Ceratophyllidae) on california ground squirrels (Rodentia: Sciuridae). ( Metzger, ME; Rust, MK, 2002)
" A total of 173 cats with flea infestation qualified as primary patients and were randomly allocated to one of the two treatments in a ratio of approximately 2:1 for metaflumizone (minimum dosage of 40mg/kg) or fipronil (at the recommended label rate)."2.73Evaluation of the efficacy and safety of a novel formulation of metaflumizone in cats naturally infested with fleas in Europe. ( Adler, K; DeLay, RL; Hellmann, K; Parker, L; Pfister, K; Rugg, D, 2007)
" One hundred eighty one dogs with tick infestation and 170 dogs with flea infestation (plus three dogs harboring both ticks and fleas) qualified as primary patients and were randomly allocated to one of two treatments in a ratio of approximately 2:1 for metaflumizone plus amitraz (minimum dosage of 20 plus 20mg/kg) or fipronil (at the recommended label rate)."2.73Evaluation of the efficacy and safety of a novel formulation of metaflumizone plus amitraz in dogs naturally infested with fleas and ticks in Europe. ( Adler, K; Delay, RL; Hellmann, K; Parker, L; Pfister, K; Rugg, D, 2007)
"Cats treated with fipronil-(S)-methoprene had significantly (P<."1.35A comparative evaluation of the speed of kill and duration of efficacy against weekly infestations with fleas on cats treated with fipronil-(S)-methoprene or metaflumizone. ( Beugnet, F; Franc, M, 2008)
"Treatment with metaflumizone provided > or = 99."1.35Efficacy of a topically applied spot-on formulation of a novel insecticide, metaflumizone, applied to cats against a flea strain (KS1) with documented reduced susceptibility to various insecticides. ( Dryden, M; Lowe, A; Mailen, S; Payne, P; Rugg, D; Smith, V, 2008)
"Fipronil spray was > or = 99."1.31Effect of 0.29% w/w fipronil spray on adult flea mortality and egg production of three different cat flea, Ctenocephalides felis (Bouché), strains infesting cats. ( Dryden, MW; Payne, PA; Ridley, RK; Smith, V, 2001)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.57)18.2507
2000's26 (74.29)29.6817
2010's6 (17.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ucan-Mézquita, A1
Jimenez-Coello, M1
Guzmán-Marín, E1
Gutierrez-Blanco, E1
Chan-Pérez, JI1
Travi, BL1
Hernandez-Cortazar, I1
Ortega-Pacheco, A1
Lopes, WDZ1
Chiummo, RM1
Vettorato, LF1
de Castro Rodrigues, D1
Sonada, RB1
Jongejan, F1
de Vos, C1
Fourie, JJ1
Beugnet, F3
Sierras, A1
Schal, C1
Franc, M5
McCoy, C1
Broce, AB1
Dryden, MW4
Schnieder, T1
Wolken, S1
Mencke, N2
Cruthers, L1
Slone, RL1
Guerrero, AJ1
Robertson-Plouch, C1
Pfister, K3
Amelotti, I1
Catalá, SS1
Gorla, DE1
Schenker, R1
Tinembart, O1
Humbert-Droz, E1
Cavaliero, T1
Yerly, B1
Medleau, L1
Clekis, T1
McArthur, TR1
Alva, R1
Barrick, RA1
Jeannin, P1
Irwin, J1
McTier, TL2
Evans, NA1
Martin-Short, M1
Gration, K1
Young, DR1
Jeannin, PC1
Boeckh, A1
Peerboom, D1
Lumeij, JT1
Smith, V4
Payne, PA2
Yao, KP1
Hellmann, K2
Adler, K2
Parker, L2
DeLay, RL2
Rugg, D3
Dryden, M2
Payne, P2
Lowe, A1
Mailen, S1
Vermot, S1
Malley, D1
Cadiergues, MC2
Araújo, FR1
Silva, MP1
Lopes, AA1
Ribeiro, OC1
Pires, PP1
Carvalho, CM1
Balbuena, CB1
Villas, AA1
Ramos, JK1
Denenberg, TM1
Bunch, S1
Ritzhaupt, LK2
Rowan, TG2
Jones, RL2
Mehlhorn, H1
Hansen, O1
Jacobs, DE1
Hutchinson, MJ1
Ryan, WG1
Szabó, MP1
Matushima, ER1
Pereira, MD1
Werther, K1
Duarte, JM1
Ridley, RK1
Caubet, C1
Metzger, ME1
Rust, MK1
Patel, A1
Lloyd, DH1
Howell, SA1
Noble, WC1

Trials

13 trials available for fipronil and Ectoparasitic Infestations

ArticleYear
Efficacy of a topical combination of fipronil-permethrin against Rhodnius prolixus on dogs.
    Veterinary parasitology, 2019, Volume: 276

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Ectoparasitic Infestations; Female; Insect Vectors;

2019
Flea blood feeding patterns in cats treated with oral nitenpyram and the topical insecticides imidacloprid, fipronil and selamectin.
    Veterinary parasitology, 2008, Oct-01, Volume: 156, Issue:3-4

    Topics: Animals; Cats; Drug Therapy, Combination; Ectoparasitic Infestations; Feeding Behavior; Female; Imid

2008
Comparative speed of kill between nitenpyram, fipronil, imidacloprid, selamectin and cythioate against adult Ctenocephalides felis (Bouché) on cats and dogs.
    Veterinary parasitology, 2003, Mar-10, Volume: 112, Issue:3

    Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Ectoparasitic Infestations; Female; Imidazoles; Ins

2003
Comparative speed of kill of selamectin, imidacloprid, and fipronil-(S)-methoprene spot-on formulations against fleas on cats.
    Veterinary therapeutics : research in applied veterinary medicine, 2005,Fall, Volume: 6, Issue:3

    Topics: Administration, Cutaneous; Animals; Cat Diseases; Cats; Chemistry, Pharmaceutical; Ectoparasitic Inf

2005
Comparison of the activity of selamectin, imidacloprid and fipronil for the treatment of cats infested experimentally with Ctenocephalides felis felis and Ctenocephalides felis strongylus.
    Veterinary parasitology, 2007, Jan-31, Volume: 143, Issue:2

    Topics: Animals; Cat Diseases; Cats; Cross-Over Studies; Ectoparasitic Infestations; Female; Imidazoles; Ins

2007
Evaluation of the efficacy and safety of a novel formulation of metaflumizone in cats naturally infested with fleas in Europe.
    Veterinary parasitology, 2007, Dec-15, Volume: 150, Issue:3

    Topics: Animals; Cat Diseases; Cats; Drug-Related Side Effects and Adverse Reactions; Ectoparasitic Infestat

2007
Evaluation of the efficacy and safety of a novel formulation of metaflumizone plus amitraz in dogs naturally infested with fleas and ticks in Europe.
    Veterinary parasitology, 2007, Dec-15, Volume: 150, Issue:3

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Ect

2007
Efficacy of selamectin and fipronil-(S)-methoprene spot-on formulations applied to cats against adult cat fleas (Ctenocephalides felis), flea eggs, and adult flea emergence.
    Veterinary therapeutics : research in applied veterinary medicine, 2007,Winter, Volume: 8, Issue:4

    Topics: Administration, Cutaneous; Animals; Cat Diseases; Cats; Ectoparasitic Infestations; Insecticides; Iv

2007
Efficacy of fipronil-(S)-methoprene on fleas, flea egg collection, and flea egg development following transplantation of gravid fleas onto treated cats.
    Veterinary therapeutics : research in applied veterinary medicine, 2007,Winter, Volume: 8, Issue:4

    Topics: Administration, Cutaneous; Animals; Cat Diseases; Cats; Ectoparasitic Infestations; Female; Insectic

2007
Control of fleas on naturally infested dogs and cats and in private residences with topical spot applications of fipronil or imidacloprid.
    Veterinary parasitology, 2000, Nov-01, Volume: 93, Issue:1

    Topics: Administration, Topical; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Ectoparasitic Infestations

2000
Evaluation of efficacy of selamectin and fipronil against Ctenocephalides felis in cats.
    Journal of the American Veterinary Medical Association, 2000, Dec-01, Volume: 217, Issue:11

    Topics: Administration, Topical; Animals; Antiparasitic Agents; Cat Diseases; Cats; Ectoparasitic Infestatio

2000
Evaluation of efficacy of selamectin, fipronil, and imidacloprid against Ctenocephalides felis in dogs.
    Journal of the American Veterinary Medical Association, 2000, Dec-01, Volume: 217, Issue:11

    Topics: Administration, Topical; Animals; Antiparasitic Agents; Dog Diseases; Dogs; Ectoparasitic Infestatio

2000
Comparison of the activity of selamectin, imidacloprid and fipronil for the treatment of dogs infested experimentally with Ctenocephalides canis and Ctenocephalides felis felis.
    The Veterinary record, 2001, Dec-08, Volume: 149, Issue:23

    Topics: Administration, Cutaneous; Animals; Dog Diseases; Dogs; Ectoparasitic Infestations; Female; Imidazol

2001

Other Studies

22 other studies available for fipronil and Ectoparasitic Infestations

ArticleYear
The effectiveness of a fixed-dose combination pour-on formulation of 1.25% fipronil and 2.5% fluazuron against economically important ectoparasites and associated pharmacokinetics in cattle.
    Parasitology international, 2017, Volume: 66, Issue:5

    Topics: Animals; Cattle; Cattle Diseases; Drug Compounding; Drug Therapy, Combination; Ectoparasitic Infesta

2017
A novel combination of fipronil and permethrin (Frontline Tri-Act®/Frontect®) reduces risk of transmission of Babesia canis by Dermacentor reticulatus and of Ehrlichia canis by Rhipicephalus sanguineus ticks to dogs.
    Parasites & vectors, 2015, Nov-19, Volume: 8

    Topics: Animals; Babesia; Babesiosis; Dermacentor; Disease Transmission, Infectious; Dog Diseases; Dogs; Dru

2015
Comparison of ingestion and topical application of insecticides against the common bed bug, Cimex lectularius (Hemiptera: Cimicidae).
    Pest management science, 2017, Volume: 73, Issue:3

    Topics: Animals; Bedbugs; Ectoparasitic Infestations; Guanidines; Insect Control; Insecticides; Ivermectin;

2017
A comparative evaluation of the speed of kill and duration of efficacy against weekly infestations with fleas on cats treated with fipronil-(S)-methoprene or metaflumizone.
    Veterinary therapeutics : research in applied veterinary medicine, 2008,Summer, Volume: 9, Issue:2

    Topics: Administration, Topical; Animals; Cat Diseases; Cats; Ectoparasitic Infestations; Female; Insecticid

2008
Comparative efficacy of imidacloprid, selamectin, fipronil-(S)-methoprene, and metaflumizone against cats experimentally infested with Ctenocephalides felis.
    Veterinary therapeutics : research in applied veterinary medicine, 2008,Fall, Volume: 9, Issue:3

    Topics: Administration, Topical; Animals; Cat Diseases; Cats; Ectoparasitic Infestations; Female; Imidazoles

2008
Evaluation of the speed of kill of fleas and ticks with Frontline Top Spot in dogs.
    Veterinary therapeutics : research in applied veterinary medicine, 2001,Spring, Volume: 2, Issue:2

    Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Ectoparasitic Infestations; Female; Insecticid

2001
Fipronil, amitraz and (S)-methoprene-a novel ectoparasiticide combination for dogs.
    Veterinary parasitology, 2011, Jul-15, Volume: 179, Issue:4

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Ectoparasitic Infestations; Insecticides; Methoprene

2011
Effects of fipronil on dogs over Triatoma infestans, the main vector of Trypanosoma cruzi, causative agent of Chagas disease.
    Parasitology research, 2012, Volume: 111, Issue:4

    Topics: Animals; Antiparasitic Agents; Dog Diseases; Dogs; Ectoparasitic Infestations; Feeding Behavior; Nym

2012
Evaluation of fipronil spot-on in the treatment of flea allergic dermatitis in dogs.
    The Journal of small animal practice, 2003, Volume: 44, Issue:2

    Topics: Administration, Cutaneous; Animals; Dermatitis, Allergic Contact; Dog Diseases; Dogs; Ectoparasitic

2003
Comparison of the activity of selamectin, fipronil, and imidacloprid against flea larvae (Ctenocephalides felis felis) in vitro.
    Veterinary parasitology, 2003, Aug-29, Volume: 116, Issue:1

    Topics: Animals; Antiparasitic Agents; Cat Diseases; Cats; Ectoparasitic Infestations; Imidazoles; Ivermecti

2003
Efficacy of fipronil/(S)-methoprene combination spot-on for dogs against shed eggs, emerging and existing adult cat fleas (Ctenocephalides felis, Bouché).
    Veterinary parasitology, 2004, Nov-10, Volume: 125, Issue:3-4

    Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Ectoparasitic Infes

2004
[Frontline contra-indicated in the rabbit].
    Tijdschrift voor diergeneeskunde, 2004, Oct-15, Volume: 129, Issue:20

    Topics: Aerosols; Animals; Antiparasitic Agents; Contraindications; Ectoparasitic Infestations; Pyrazoles; R

2004
Efficacy of a topically applied spot-on formulation of a novel insecticide, metaflumizone, applied to cats against a flea strain (KS1) with documented reduced susceptibility to various insecticides.
    Veterinary parasitology, 2008, Jan-25, Volume: 151, Issue:1

    Topics: Administration, Topical; Animals; Cat Diseases; Cats; Dose-Response Relationship, Drug; Drug Resista

2008
Use of frontline spray in rabbits.
    The Veterinary record, 1997, Jun-21, Volume: 140, Issue:25

    Topics: Aerosols; Animals; Drug Labeling; Ectoparasitic Infestations; Guidelines as Topic; Insecticides; Pyr

1997
Antifeeding effect of several insecticidal formulations against Ctenocephalides felis on cats.
    Parasite (Paris, France), 1998, Volume: 5, Issue:1

    Topics: Administration, Topical; Aerosols; Animals; Cat Diseases; Cats; Dichlorvos; Ectoparasitic Infestatio

1998
Severe cat flea infestation of dairy calves in Brazil.
    Veterinary parasitology, 1998, Dec-15, Volume: 80, Issue:1

    Topics: Animal Husbandry; Animals; Blood Transfusion; Brazil; Cattle; Cattle Diseases; Ectoparasitic Infesta

1998
Comparative study on the effects of three insecticides (fipronil, imidacloprid, selamectin) on developmental stages of the cat flea (Ctenocephalides felis Bouché 1835): a light and electron microscopic analysis of in vivo and in vitro experiments.
    Parasitology research, 2001, Volume: 87, Issue:3

    Topics: Animals; Cats; Dog Diseases; Dogs; Ectoparasitic Infestations; Female; Imidazoles; In Vitro Techniqu

2001
Control of flea populations in a simulated home environment model using lufenuron, imidacloprid or fipronil.
    Medical and veterinary entomology, 2001, Volume: 15, Issue:1

    Topics: Animals; Benzamides; Cat Diseases; Cats; Ectoparasitic Infestations; Housing; Imidazoles; Insect Con

2001
Cat flea (Ctenocephalides felis) infestation in quarantined marsh deer (Blastocerus dichotomus) populations.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2000, Volume: 31, Issue:4

    Topics: Animals; Animals, Zoo; Brazil; Deer; Disease Outbreaks; Ectoparasitic Infestations; Insecticides; Py

2000
Effect of 0.29% w/w fipronil spray on adult flea mortality and egg production of three different cat flea, Ctenocephalides felis (Bouché), strains infesting cats.
    Veterinary parasitology, 2001, Dec-28, Volume: 102, Issue:4

    Topics: Animals; Cat Diseases; Cats; Ectoparasitic Infestations; Female; Insect Control; Insecticides; Male;

2001
Laboratory evaluation of fipronil and imidacloprid topical insecticides for control of the plague vector Oropsylla montana (Siphonaptera: Ceratophyllidae) on california ground squirrels (Rodentia: Sciuridae).
    Journal of medical entomology, 2002, Volume: 39, Issue:1

    Topics: Animals; California; Ectoparasitic Infestations; Female; Imidazoles; Insect Control; Insect Vectors;

2002
Investigation into the potential pathogenicity of Staphylococcus felis in a cat.
    The Veterinary record, 2002, May-25, Volume: 150, Issue:21

    Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Cat Diseases; Cats; D

2002