fipronil has been researched along with Chemical and Drug Induced Liver Injury in 6 studies
fipronil: has low mammalian toxicity; structure given in first source
fipronil : A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile : A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fipronil is a broad-spectrum phenylpyrazole insecticide and has been used effectively in the agriculture." | 5.72 | P-coumaric acid ameliorates fipronil induced liver injury in mice through attenuation of structural changes, oxidative stress and inflammation. ( Bal, SS; Leishangthem, GD; Sethi, RS; Singh, A, 2022) |
| "Fipronil is a broad-spectrum phenylpyrazole insecticide and has been used effectively in the agriculture." | 1.72 | P-coumaric acid ameliorates fipronil induced liver injury in mice through attenuation of structural changes, oxidative stress and inflammation. ( Bal, SS; Leishangthem, GD; Sethi, RS; Singh, A, 2022) |
| "Fipronil is an insecticide used to control pests in animals and plants that can causes hepatotoxicity in animals and humans, and it is hepatically metabolized to fipronil sulfone by cytochrome P-450." | 1.42 | Effect of fipronil on energy metabolism in the perfused rat liver. ( Constantin, J; de Medeiros, HC; Ishii-Iwamoto, EL; Mingatto, FE, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bal, SS | 1 |
| Leishangthem, GD | 1 |
| Sethi, RS | 1 |
| Singh, A | 1 |
| Mendonça, JDS | 1 |
| de Almeida, JCN | 1 |
| Vieira, LG | 1 |
| Hirano, LQL | 1 |
| Santos, ALQ | 1 |
| Andrade, DV | 1 |
| Malafaia, G | 1 |
| de Oliveira Júnior, RJ | 1 |
| Beletti, ME | 1 |
| Elgawish, RA | 1 |
| Abdelrazek, HMA | 1 |
| Ismail, SAA | 1 |
| Loutfy, NM | 1 |
| Soliman, MTA | 1 |
| Sayed, AA | 1 |
| El-Desouky, MA | 1 |
| Ibrahim, KA | 1 |
| de Medeiros, HC | 1 |
| Constantin, J | 1 |
| Ishii-Iwamoto, EL | 1 |
| Mingatto, FE | 1 |
| Ferreira, M | 1 |
| De Oliveira, PR | 1 |
| Denardi, SE | 1 |
| Bechara, GH | 1 |
| Mathias, MI | 1 |
6 other studies available for fipronil and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
P-coumaric acid ameliorates fipronil induced liver injury in mice through attenuation of structural changes, oxidative stress and inflammation.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injur | 2022 |
Mutagenicity, hepatotoxicity, and neurotoxicity of glyphosate and fipronil commercial formulations in Amazon turtles neonates (Podocnemis expansa).
Topics: Animals; Chemical and Drug Induced Liver Injury; Glyphosate; Mutagens; Pesticides; Turtles; Water Po | 2023 |
Hepatoprotective activity of Uncaria tomentosa extract against sub-chronic exposure to fipronil in male rats.
Topics: Animals; Antioxidants; Cat's Claw; Cell Line; Chemical and Drug Induced Liver Injury; Environmental | 2019 |
Garlic and allopurinol attenuate hepatic apoptosis induced by fipronil in male albino rats.
Topics: Allopurinol; Animals; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Garlic; Glutathi | 2019 |
Effect of fipronil on energy metabolism in the perfused rat liver.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chloride Channels; Cytochrome P- | 2015 |
Action of the chemical agent fipronil (active ingredient of acaricide Frontline®) on the liver of mice: an ultrastructural analysis.
Topics: Acaricides; Animals; Cell Death; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cytoplasm; En | 2012 |