Page last updated: 2024-09-02

fingolimod hydrochloride and Pregnancy

fingolimod hydrochloride has been researched along with Pregnancy in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (2.27)	29.6817
2010's	22 (50.00)	24.3611
2020's	21 (47.73)	2.80

Authors

Authors	Studies
Bianco, A; Centonze, D; De Arcangelis, V; De Fino, C; De Luca, G; Di Lemme, S; Di Tommaso, V; Evangelista, L; Fantozzi, R; Lucchini, M; Mirabella, M; Pastorino, R; Presicce, G; Totaro, R	1
Adamkova, J; Ampapa, R; Hanulikova, P; Horakova, D; Hradilek, P; Mares, J; Meluzinova, E; Pavliska, L; Stetkarova, I; Stourac, P; Vachova, M; Valis, M; Woznicova, I; Zapletalova, O	1
Callens, A; Coustans, M; Edan, G; Jourdain, A; Lallement, F; Laplaud, D; Le Page, E; Leblanc, S; Leray, E; Michel, L; Videt, D; Wiertlewski, S	1
De Sèze, J; Edan, G; Kerbrat, A; Laplaud, DA; Le Page, E; Lebrun-Frenay, C; Lefort, M; Leguy, S; Leray, E; Lescot, L; Michel, L; Vukusic, S; Wiertlewski, S	1
Haug, U; Kollhorst, B; Platzbecker, K; Wentzell, N	1
Affinito, G; Brescia Morra, V; Carotenuto, A; Di Gennaro, M; Fumo, MG; Giordana, R; Lanzillo, R; Mercogliano, M; Moccia, M; Palladino, R; Petracca, M; Triassi, M	1
Ciplea, AI; Gold, R; Hellwig, K; Hemat, S; Langer-Gould, AM; Thiel, S; Timmesfeld, N; Tokic, M	1
Marulanda, E; Tornes, L	1
Aguera-Morales, E; Al-Asmi, A; Al-Harbi, TM; Alroughani, R; Altintas, A; Ampapa, R; Bergamaschi, R; Boz, C; Butzkueven, H; Cartechini, E; Castillo-Trivino, T; Csepany, T; de Gans, K; Diouf, I; Duquette, P; Eichau, S; Ferraro, D; Gerlach, O; Gouider, R; Grammond, P; Grand'Maison, F; Granella, F; Gray, O; Hodgkinson, S; Horakova, D; Hughes, S; Iuliano, G; Kalincik, T; Kappos, L; Karabudak, R; Kubala Havrdova, E; Laureys, G; Lechner-Scott, J; Lugaresi, A; Malpas, CB; McCombe, PA; McGuigan, C; Onofrj, M; Ozakbas, S; Patti, F; Prat, A; Roos, I; Sa, MJ; Sánchez-Menoyo, JL; Sempere, AP; Sharmin, S; Shaw, C; Shaygannejad, V; Sidhom, Y; Slee, M; Sola, P; Solaro, C; Stuart, EA; Terzi, M; Treviño Frenk, I; van der Walt, A; Vucic, S; Yamout, B	1
Ariño, H; Baños, N; Blanco, Y; Llufriu, S; Martinez-Hernandez, E; Martinez-Lapiscina, EH; Montejo, C; Pulido-Valdeolivas, I; Reyes, D; Saiz, A; Sepúlveda, M; Sola-Valls, N; Zubizarreta, I	1
Arlauskienė, A; Laužikienė, D; Ramašauskaitė, D; Varytė, G; Zakarevičienė, J	1
Geissbühler, Y; Moore, A; Rezaallah, B	1
Fujimoto, M; Ikebuchi, R; Kobayashi, K; Kusumoto, Y; Moriya, T; Tomura, M	1
Addor, MC; Agusti, A; Baud, D; Buclin, T; Cottin, J; Diav-Citrin, O; Kadioglu, M; Kaplan, YC; Kennedy, D; Livio, F; Onken, M; Panchaud, A; Pauliat, E; Rollason, V; Rothuizen, LE; Rousson, V; Théaudin, M; Weber-Schoendorfer, C; Winterfeld, U	1
Asci, H; Eris Yalcin, S; Ozmen, O; Sezik, M; Yavuz, A	1
Azami, S; Konoeda, F; Sato, H	1
Ekobena, P; Ivanyuk, A; Livio, F	1
Callegari, I; Derfuss, T; Galli, E	1
Asci, H; Ozmen, O; Savran, M; Sezik, M; Yalcin, SE; Yavuz, A	1
Arlauskienė, A; Ramašauskaitė, D; Varytė, G	1
Bonifácio, G; Correia, F; Costa, A; Ferro, D; Gonçalves, AI; Guerreiro, RP; Loureiro, JL; Pinheiro, J; Rocha, R; Rodrigues, R; Sá, MJ; Sabença, F; Vale, J	1
Asci, H; Ozmen, O; Sezik, M; Yavuz, A	1
Havla, J; Hohlfeld, R; Kümpfel, T; Meinl, I	1
Navardi, S; Sahraian, MA	1
Chen, W; Ghobrial, RM; Kloc, M; Li, XC	1
Li, L; Liu, Y; Wang, J; Xiong, M; Xu, L; Zhou, F; Zhu, J	1
Baghbanian, SM; Cheraghmakani, H; Nasehi, MM	1
Berenguer-Ruiz, L; Gimenez-Martinez, J; Palazón-Bru, A; Sempere, AP	1
Berenguer-Ruiz, L; Feliu-Rey, E; Sempere, AP	1
Airas, L; Malm, H; Ruuskanen, J	1
Alwan, S; Dahlgren, L; Lu, E; Sadovnick, AD; Synnes, A; Tremlett, H; Wang, BW	1
Langer-Gould, AM	1
Cohen, JA; Collins, W; Francis, G; Heining, P; Kappos, L; Karlsson, G; Koren, G; Zhang, X	1
Baumann, JM; Bhaumik, SK; Chougnet, CA; Dunn, RS; Kallapur, SG; Kuan, CY; Lee, YH; Lewkowich, IP; Li, Y; Lin, SH; Lin, X; Lindquist, DM; Liu, CY; Murali-Krishna, K; Shie, FS; Sun, YY; Wills-Karp, M; Yang, D; Zhang, Y	1
Berlit, P; Herold, M; Kraemer, M; Weber, R	1
Bendix, I; Felderhoff-Müser, U; Hadamitzky, M; Hansen, W; Herrmann, R; Herz, J; Heumann, R; Hou, X; Kempe, K; Lumpe, K; Reinboth, BS; Serdar, M; Sifringer, M; Sizonenko, SV; van de Looij, Y	1
Klebe, D; Krafft, PR; LeGrand, J; Lekic, T; Rolland, WB; Weldon, AJ; Xu, L; Zhang, JH	1
Casper, RF; Dertinger, SD; Fanton, JK; Jacob, DS; Jurisicova, A; Lawson, MS; Murphy, MK; Pau, KY; Tilly, JL; Toscano, NP; Zelinski, MB	1
Chen, L; Di, J; Li, DJ; Li, W; Lin, Y; Ren, L; Shan, B; Sun, Y; Wang, W	1
Baker, D; Giovannoni, G; Jackson, SJ	1
Aguilera, C; Tintoré, M; Tur, C	1
Barde, YA; Dekkers, MP; Deogracias, R; Guy, J; Ionescu, MC; Vogt, KE; Yazdani, M	1
Gardner, NM; Gelineau-van Waes, J; Maddox, JR; Rainey, MA; Riley, RT; Sachs, AJ; Voss, KA; Wilberding, JD	1
Dev, KK; Mullershausen, F; Osinde, M	1

Reviews

6 review(s) available for fingolimod hydrochloride and Pregnancy

Article	Year
Pregnancy and Multiple Sclerosis: An Update on the Disease Modifying Treatment Strategy and a Review of Pregnancy's Impact on Disease Activity. Medicina (Kaunas, Lithuania), 2020, Jan-21, Volume: 56, Issue:2 Topics: Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Interferon-beta; Multiple Sclerosis; Natalizumab; Nitriles; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Rituximab; Toluidines	2020
[Pharmacovigilance update]. Revue medicale suisse, 2021, Jan-13, Volume: 17, Issue:720-1 Topics: Adenosine Monophosphate; Alanine; Cleft Lip; Contraindications, Drug; COVID-19 Drug Treatment; Cytokine Release Syndrome; Female; Fingolimod Hydrochloride; Humans; Hydroxychloroquine; Leiomyoma; Norpregnadienes; Pharmacokinetics; Pharmacovigilance; Pregnancy; Ranitidine; Safety-Based Drug Withdrawals; Skin Neoplasms	2021
Update on treatment in multiple sclerosis. Presse medicale (Paris, France : 1983), 2021, Volume: 50, Issue:2 Topics: Abnormalities, Drug-Induced; Algorithms; Antibodies, Monoclonal, Humanized; Cladribine; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Hematopoietic Stem Cell Transplantation; Humans; Hydroxybutyrates; Immunologic Factors; Immunosuppressive Agents; Indans; Interferon-beta; Male; Mitoxantrone; Multiple Sclerosis; Natalizumab; Nitriles; Oxadiazoles; Pregnancy; Sphingosine 1 Phosphate Receptor Modulators; Sphingosine-1-Phosphate Receptors; Toluidines	2021
Pregnancy and multiple sclerosis: an update. Current opinion in obstetrics & gynecology, 2021, 10-01, Volume: 33, Issue:5 Topics: Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Infant; Multiple Sclerosis; Natalizumab; Pregnancy	2021
[Multiple sclerosis and pregnancy]. Duodecim; laaketieteellinen aikakauskirja, 2013, Volume: 129, Issue:14 Topics: Female; Fetus; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunosuppressive Agents; Interferon-beta; Maternal-Fetal Exchange; Multiple Sclerosis; Peptides; Pregnancy; Propylene Glycols; Recurrence; Sphingosine	2013
A review of safety-related pregnancy data surrounding the oral disease-modifying drugs for multiple sclerosis. CNS drugs, 2014, Volume: 28, Issue:2 Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Fumarates; Humans; Hydroxybutyrates; Immunologic Factors; Multiple Sclerosis; Nitriles; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Propylene Glycols; Sphingosine; Toluidines	2014

Trials

1 trial(s) available for fingolimod hydrochloride and Pregnancy

Article	Year
Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial. Journal of neurology, neurosurgery, and psychiatry, 2023, Volume: 94, Issue:12 Topics: Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunosuppressive Agents; Interferon-beta; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Pregnancy; Recurrence	2023

Article

Year

Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial.

Journal of neurology, neurosurgery, and psychiatry, 2023, Volume: 94, Issue:12

Topics: Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunosuppressive Agents; Interferon-beta; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Pregnancy; Recurrence

2023

Other Studies

37 other study(ies) available for fingolimod hydrochloride and Pregnancy

Article	Year
Disease Reactivation after Fingolimod Discontinuation in Pregnant Multiple Sclerosis Patients. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:4 Topics: Adult; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Pregnancy; Recurrence; Retrospective Studies	2021
Is pregnancy in MS patients safe and what is its impact on MS course? Real World evidence of 1533 pregnancies in Czech Republic. Multiple sclerosis and related disorders, 2022, Volume: 59 Topics: Czech Republic; Female; Fingolimod Hydrochloride; Humans; Multiple Sclerosis; Natalizumab; Pregnancy; Retrospective Studies	2022
Disease reactivation after fingolimod cessation in Multiple Sclerosis patients with pregnancy desire: A retrospective study. Multiple sclerosis and related disorders, 2022, Volume: 66 Topics: Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Pregnancy; Recurrence; Retrospective Studies	2022
Disease modifying therapies and disease activity during pregnancy and postpartum in a contemporary cohort of relapsing Multiple Sclerosis patients. Multiple sclerosis and related disorders, 2022, Volume: 68 Topics: Female; Fingolimod Hydrochloride; Humans; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Postpartum Period; Pregnancy; Recurrence	2022
Fingolimod, teriflunomide and cladribine for the treatment of multiple sclerosis in women of childbearing age: description of drug utilization and exposed pregnancies in Germany. Multiple sclerosis and related disorders, 2022, Volume: 67 Topics: Child; Cladribine; Cross-Sectional Studies; Drug Utilization; Female; Fingolimod Hydrochloride; Germany; Humans; Immunosuppressive Agents; Infant, Newborn; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Pregnancy	2022
Fertility, pregnancy and childbirth in women with multiple sclerosis: a population-based study from 2018 to 2020. Journal of neurology, neurosurgery, and psychiatry, 2023, Volume: 94, Issue:9 Topics: Dimethyl Fumarate; Female; Fertility; Fingolimod Hydrochloride; Humans; Multiple Sclerosis; Natalizumab; Pregnancy	2023
Multiple Sclerosis Disease Activity and Disability Following Cessation of Fingolimod for Pregnancy. Neurology(R) neuroimmunology & neuroinflammation, 2023, Volume: 10, Issue:4 Topics: Adult; Female; Fingolimod Hydrochloride; Humans; Multiple Sclerosis; Postpartum Period; Pregnancy; Recurrence; Registries	2023
Obstetric and Gynecologic Disorders and the Nervous System. Continuum (Minneapolis, Minn.), 2023, 06-01, Volume: 29, Issue:3 Topics: Breast Feeding; Female; Fingolimod Hydrochloride; Humans; Hypertension; Multiple Sclerosis; Pregnancy	2023
Rebound of multiple sclerosis activity after fingolimod withdrawal due to planning pregnancy: Analysis of predisposing factors. Multiple sclerosis and related disorders, 2020, Volume: 38 Topics: Adult; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Live Birth; Lymphocytes; Magnetic Resonance Imaging; Multiple Sclerosis; Pregnancy; Pregnancy Complications; Reproductive Behavior; Retrospective Studies; Severity of Illness Index; Symptom Flare Up; Time Factors	2020
An alternative to product-specific pregnancy registries? PRIM; PRegnancy outcomes Intensive Monitoring. Reproductive toxicology (Elmsford, N.Y.), 2020, Volume: 94 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Drug Industry; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Maternal-Fetal Exchange; Middle Aged; Multiple Sclerosis; Pharmacovigilance; Pregnancy; Pregnancy Outcome; Registries; Young Adult	2020
T cells are the main population in mouse breast milk and express similar profiles of tight junction proteins as those in mammary alveolar epithelial cells. Journal of reproductive immunology, 2020, Volume: 140 Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Epithelial Cells; Female; Fingolimod Hydrochloride; Forkhead Transcription Factors; Humans; Lactation; Mammary Glands, Animal; Mammary Glands, Human; Mice; Mice, Knockout; Milk; Pregnancy; T-Lymphocytes; Tight Junction Proteins	2020
Pregnancy outcome following first-trimester exposure to fingolimod: A collaborative ENTIS study. Multiple sclerosis (Houndmills, Basingstoke, England), 2021, Volume: 27, Issue:3 Topics: Cohort Studies; Female; Fingolimod Hydrochloride; Humans; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies	2021
Immunohistochemical analysis of protective effects of maternal fingolimod on the placenta and fetal lung and brain in chorioamnionitis-induced preterm birth rat model. Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Brain; Chorioamnionitis; Disease Models, Animal; Female; Fingolimod Hydrochloride; Immunohistochemistry; Inflammation Mediators; Lipopolysaccharides; Lung; Placenta; Pregnancy; Premature Birth; Rats, Wistar	2020
[A patient with relapsing-remitting multiple sclerosis who relapsed frequently and developed primary biliary cholangitis after pregnancy and discontinuation of fingolimod]. Rinsho shinkeigaku = Clinical neurology, 2021, Jan-29, Volume: 61, Issue:1 Topics: Adult; Autoantibodies; Biomarkers; Diagnosis, Differential; Female; Fingolimod Hydrochloride; Humans; Liver Cirrhosis, Biliary; Magnetic Resonance Imaging; Mitochondria; Multiple Sclerosis; Pregnancy; Pregnancy Complications; Recurrence; Withholding Treatment	2021
Combined Use of Magnesium Sulfate and Fingolimod for Antenatal Neuroprotection against Inflammation-Mediated Experimental Preterm Brain Injury in a Rat Model. Fetal and pediatric pathology, 2022, Volume: 41, Issue:4 Topics: Animals; Brain Injuries; Endotoxins; Female; Fingolimod Hydrochloride; Humans; Inflammation; Interleukin-10; Interleukin-6; Magnesium Sulfate; Neuroprotection; Neuroprotective Agents; Pregnancy; Rats	2022
Therapeutic inertia in relapsing-remitting multiple sclerosis. Multiple sclerosis and related disorders, 2021, Volume: 55 Topics: Adult; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Male; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Pregnancy	2021
Fingolimod against endotoxin-induced fetal brain injury in a rat model. The journal of obstetrics and gynaecology research, 2017, Volume: 43, Issue:11 Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Disease Models, Animal; Endotoxins; Female; Fetal Diseases; Fingolimod Hydrochloride; Inflammation; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar	2017
Recurrence of disease activity during pregnancy after cessation of fingolimod in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2018, Volume: 24, Issue:7 Topics: Adult; Disease Progression; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Pregnancy; Pregnancy Complications; Recurrence	2018
A case of dextrocardia following maternal exposure to generic Fingolimod during the first trimester of pregnancy. Multiple sclerosis and related disorders, 2018, Volume: 21 Topics: Dextrocardia; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy, Unplanned	2018
Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages. Immunobiology, 2018, Volume: 223, Issue:11 Topics: Actin Cytoskeleton; Animals; Cells, Cultured; Extracellular Matrix; Female; Fingolimod Hydrochloride; Macrophages, Peritoneal; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Multiple Sclerosis; p21-Activated Kinases; Podosomes; Pregnancy; rac1 GTP-Binding Protein; Rapamycin-Insensitive Companion of mTOR Protein; rhoA GTP-Binding Protein	2018
The experimental research of pregnancy immune tolerance induced by FTY720 via blocking S1P signal transduction pathway. Journal of cellular biochemistry, 2019, Volume: 120, Issue:4 Topics: Abortion, Spontaneous; Animals; Decidua; Dendritic Cells; Female; Fingolimod Hydrochloride; Humans; Immune Tolerance; Lentivirus; Mice; Mice, Inbred BALB C; Pregnancy; RNA, Small Interfering; Signal Transduction; Sphingosine-1-Phosphate Receptors	2019
Neurodevelopmental retardation in a baby born to a multiple sclerosis patient being treated with fingolimod. Multiple sclerosis and related disorders, 2019, Volume: 33 Topics: Child, Preschool; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Infant, Newborn; Intellectual Disability; Multiple Sclerosis; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects	2019
Relapses and obstetric outcomes in women with multiple sclerosis planning pregnancy. Journal of neurology, 2019, Volume: 266, Issue:10 Topics: Adult; Disease Progression; Female; Fingolimod Hydrochloride; Follow-Up Studies; Glatiramer Acetate; Humans; Immunologic Factors; Interferon-beta; Multiple Sclerosis; Natalizumab; Pregnancy; Pregnancy Complications; Puerperal Disorders; Recurrence; Reproductive Behavior	2019
Rebound of disease activity during pregnancy after withdrawal of fingolimod. European journal of neurology, 2013, Volume: 20, Issue:8 Topics: Adult; Anti-Inflammatory Agents; Disability Evaluation; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting; Pregnancy; Pregnancy Complications; Propylene Glycols; Sphingosine	2013
The pill times 2: what every woman with multiple sclerosis should know. Neurology, 2014, Feb-25, Volume: 82, Issue:8 Topics: Abnormalities, Drug-Induced; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Pregnancy; Pregnancy Complications; Propylene Glycols; Sphingosine	2014
Pregnancy outcomes in the clinical development program of fingolimod in multiple sclerosis. Neurology, 2014, Feb-25, Volume: 82, Issue:8 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Middle Aged; Multiple Sclerosis; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Propylene Glycols; Sphingosine	2014
Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Dec-03, Volume: 34, Issue:49 Topics: Animals; Animals, Newborn; Atrophy; Blood-Brain Barrier; Brain; Cell Movement; Chorioamnionitis; Cytokines; Dose-Response Relationship, Drug; Female; Fingolimod Hydrochloride; Humans; Hypoxia-Ischemia, Brain; Immunosuppressive Agents; Infant, Newborn; Inflammation; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; NF-kappa B; Pregnancy; Propylene Glycols; Rats; Receptors, Interleukin; Sphingosine; T-Lymphocytes; White Matter	2014
Reversible cerebral vasoconstriction syndrome associated with fingolimod treatment in relapsing-remitting multiple sclerosis three months after childbirth. Multiple sclerosis (Houndmills, Basingstoke, England), 2015, Volume: 21, Issue:11 Topics: Adult; Cerebrovascular Disorders; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Parturition; Pregnancy; Syndrome; Vasoconstriction	2015
Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. Brain, behavior, and immunity, 2016, Volume: 52 Topics: Animals; Animals, Newborn; Brain; Cognition Disorders; Diffusion Magnetic Resonance Imaging; Female; Fingolimod Hydrochloride; Hyperoxia; Lysophospholipids; Male; Microglia; Nerve Fibers, Myelinated; Oligodendroglia; Oxygen; Pregnancy; Random Allocation; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; White Matter	2016
Fingolimod confers neuroprotection through activation of Rac1 after experimental germinal matrix hemorrhage in rat pups. Journal of neurochemistry, 2017, Volume: 140, Issue:5 Topics: Animals; Body Water; Brain; Brain Chemistry; Brain Edema; Cognition; Female; Fingolimod Hydrochloride; Intracranial Hemorrhages; Leukocyte Count; Male; Neuroprotective Agents; Oxadiazoles; Phosphoserine; Pregnancy; Pyrones; Quinolines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Thiophenes; Tight Junction Proteins	2017
In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates. Fertility and sterility, 2011, Mar-15, Volume: 95, Issue:4 Topics: Adult; Age Factors; Animals; Drug Delivery Systems; Female; Fingolimod Hydrochloride; Humans; Infertility, Female; Macaca mulatta; Male; Mice; Ovarian Diseases; Ovary; Pregnancy; Pregnancy Outcome; Propylene Glycols; Radiation Injuries, Experimental; Radiation-Protective Agents; Sphingosine; Young Adult	2011
FTY720-induced conversion of conventional Foxp3- CD4+ T cells to Foxp3+ regulatory T cells in NOD mice. American journal of reproductive immunology (New York, N.Y. : 1989), 2011, Volume: 66, Issue:5 Topics: Animals; CD4-Positive T-Lymphocytes; Disease Models, Animal; Embryo Loss; Female; Fingolimod Hydrochloride; Forkhead Transcription Factors; Humans; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Pregnancy; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine; T-Lymphocytes, Regulatory	2011
Fingolimod modulates microglial activation to augment markers of remyelination. Journal of neuroinflammation, 2011, Jul-05, Volume: 8 Topics: Animals; Biomarkers; Cell Culture Techniques; Cells, Cultured; Demyelinating Diseases; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Lysophosphatidylcholines; Microglia; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Myelin Sheath; Nerve Degeneration; Pregnancy; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Spheroids, Cellular; Sphingosine	2011
[Disease modifying drugs in multiple sclerosis and pregnancy]. Medicina clinica, 2012, Sep-22, Volume: 139, Issue:7 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Antibodies, Monoclonal, Humanized; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunologic Factors; Immunosuppressive Agents; Infant, Newborn; Interferon-beta; Multiple Sclerosis; Natalizumab; Peptides; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Propylene Glycols; Sphingosine; Stillbirth	2012
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America, 2012, Aug-28, Volume: 109, Issue:35 Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; MAP Kinase Signaling System; Methyl-CpG-Binding Protein 2; Mice; Motor Activity; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Propylene Glycols; Receptors, Lysosphingolipid; Rett Syndrome; Sphingosine	2012
Increased sphingoid base-1-phosphates and failure of neural tube closure after exposure to fumonisin or FTY720. Birth defects research. Part A, Clinical and molecular teratology, 2012, Volume: 94, Issue:10 Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Fingolimod Hydrochloride; Fumonisins; Mice; Mice, Inbred Strains; Models, Biological; Neural Tube Defects; Pregnancy; Prenatal Exposure Delayed Effects; Propylene Glycols; Sphingosine; Up-Regulation	2012
Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors. Neuropharmacology, 2007, Volume: 52, Issue:5 Topics: Animals; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Extracellular Signal-Regulated MAP Kinases; Female; Fingolimod Hydrochloride; GTP-Binding Protein alpha Subunits, Gi-Go; Immunohistochemistry; Pertussis Toxin; Phosphorylation; Pregnancy; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine	2007