Page last updated: 2024-09-02

fingolimod hydrochloride and Neoplasms

fingolimod hydrochloride has been researched along with Neoplasms in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's14 (60.87)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Askari, M; Ghaffary, EM; Ghajarzadeh, M; Ghoshouni, H; Mirmosayyeb, O; Shaygannejad, V1
Alping, P; Askling, J; Burman, J; Fink, K; Fogdell-Hahn, A; Frisell, T; Gunnarsson, M; Hillert, J; Langer-Gould, A; Lycke, J; Nilsson, P; Olsson, T; Piehl, F; Salzer, J; Svenningsson, A; Vrethem, M1
Ackermann, CJ; Berner, F; Diem, S; Flatz, L; Hasan Ali, O; Hundsberger, T; Markert, E; Moulin, A; Müller, J; Müller, S; Pop, OT; Ring, SS1
Espinosa-Rosso, R; Gil-Bernal, R; Gómez-Gómez, C; González-Caballero, JL1
Anders, RA; Carrera-Haro, MA; Drake, CG; Ghasemzadeh, A; Kochel, CM; Lopez-Bujanda, Z; Mao, W; Marciscano, AE; Meeker, AK; Muroyama, Y; Nirschl, TR; Pardoll, DM; Tam, AJ; Theodros, D; Thoburn, CJ; Uddin, M; Velarde, E1
Rommer, PS; Zettl, UK1
Cong, ZX; Ji, XJ; Wang, HD; Zhang, L; Zhou, Y; Zhu, JH1
Hla, T; Proia, RL1
Chen, B; Edinger, AL; Fallegger, D; Fransson, R; Hanessian, S; Huwiler, A; Keebaugh, A; Kleinman, MT; McCracken, AN; McMonigle, RJ; Roy, SG; Selwan, E1
Cristóbal, I; García-Foncillas, J; González-Alonso, P; Madoz-Gúrpide, J; Manso, R; Rojo, F1
Alshaker, H; Cooper, C; Pchejetski, D; White, C; Winkler, M1
Carratù, MR; De Rasmo, D; Reale, A; Signorile, A; Vacca, A1
Milstien, S; Paugh, SW; Spiegel, S; Takabe, K1
Abdollahi, A; Domhan, S; Zeier, M1
Peyruchaud, O1
McFadden, G; Werden, SJ1
Engelhard, VH; Enriquez, HL; Fu, YX; Thompson, ED1
Eshhar, Z; Marcus, A; Waks, T1
Hla, T; Obinata, H1
Bittman, R; Pyne, NJ; Pyne, S1
Lopez, AF; Pitman, MR; Pitson, SM; Woodcock, JM1
Huwiler, A; Pfeilschifter, J1
Morel, D1

Reviews

12 review(s) available for fingolimod hydrochloride and Neoplasms

ArticleYear
Incidence of cancer in patients with multiple sclerosis (MS) who were treated with fingolimod: A systematic review and meta-analysis.
    Multiple sclerosis and related disorders, 2022, Volume: 59

    Topics: Fingolimod Hydrochloride; Humans; Immunologic Factors; Immunosuppressive Agents; Incidence; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Neoplasms

2022
Managing the side effects of multiple sclerosis therapy: pharmacotherapy options for patients.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:5

    Topics: Alemtuzumab; Cladribine; Crotonates; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Immunologic Factors; Immunosuppressive Agents; Interferon-beta; Multiple Sclerosis; Natalizumab; Neoplasms; Nitriles; Toluidines

2018
FTY720 for cancer therapy (Review).
    Oncology reports, 2013, Volume: 30, Issue:6

    Topics: Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Neoplasms; Phosphorylation; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine; United States; United States Food and Drug Administration

2013
Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.
    The Journal of clinical investigation, 2015, Volume: 125, Issue:4

    Topics: Acute Lung Injury; Anemia, Sickle Cell; Animals; Autoimmune Diseases; Cardiovascular Diseases; Cell Physiological Phenomena; Disease Models, Animal; Fingolimod Hydrochloride; Hematopoietic Stem Cell Mobilization; Humans; Influenza, Human; Lysophospholipids; Membrane Lipids; Mice; Multiple Sclerosis; Neoplasms; Neovascularization, Physiologic; Neurogenesis; Propylene Glycols; Receptors, Lysosphingolipid; Sphingolipids; Sphingosine

2015
Potential anti-tumor effects of FTY720 associated with PP2A activation: a brief review.
    Current medical research and opinion, 2016, Volume: 32, Issue:6

    Topics: Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Neoplasms; Protein Phosphatase 2

2016
The emerging role of FTY720 (Fingolimod) in cancer treatment.
    Oncotarget, 2016, Apr-26, Volume: 7, Issue:17

    Topics: Animals; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Neoplasms; Prognosis; Proto-Oncogene Mas; Signal Transduction

2016
Pharmacological Activation of Protein Phosphatase 2 A (PP2A): A Novel Strategy to Fight Against Human Malignancies?
    Current medicinal chemistry, 2016, Volume: 23, Issue:38

    Topics: Antineoplastic Agents; Biological Products; Bortezomib; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt

2016
"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets.
    Pharmacological reviews, 2008, Volume: 60, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Enzyme Activation; Fingolimod Hydrochloride; Humans; Hypersensitivity; Immunosuppressive Agents; Lysophospholipids; Multiple Sclerosis; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sulfhydryl Compounds

2008
Novel implications for lysophospholipids, lysophosphatidic acid and sphingosine 1-phosphate, as drug targets in cancer.
    Anti-cancer agents in medicinal chemistry, 2009, Volume: 9, Issue:4

    Topics: Fingolimod Hydrochloride; Humans; Lysophospholipids; Neoplasms; Propylene Glycols; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Sphingosine

2009
Sphingosine 1-phosphate in coagulation and inflammation.
    Seminars in immunopathology, 2012, Volume: 34, Issue:1

    Topics: Animals; Atherosclerosis; Blood Coagulation; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Lymph Nodes; Lymphocytes; Lysophospholipids; Multiple Sclerosis; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Propylene Glycols; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Tumor Necrosis Factor-alpha

2012
Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules.
    Cancer research, 2011, Nov-01, Volume: 71, Issue:21

    Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Cell Division; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fingolimod Hydrochloride; Humans; Lysophospholipids; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Sphingosine; Vinyl Compounds

2011
Molecular targets of FTY720 (fingolimod).
    Current molecular medicine, 2012, Volume: 12, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Lymphopenia; Lysophospholipids; Multiple Sclerosis; Neoplasms; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine

2012

Other Studies

11 other study(ies) available for fingolimod hydrochloride and Neoplasms

ArticleYear
Cancer Risk for Fingolimod, Natalizumab, and Rituximab in Multiple Sclerosis Patients.
    Annals of neurology, 2020, Volume: 87, Issue:5

    Topics: Adult; Cohort Studies; Female; Fingolimod Hydrochloride; Humans; Immunologic Factors; Incidence; Male; Middle Aged; Multiple Sclerosis; Natalizumab; Neoplasms; Rituximab; Sweden

2020
Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients.
    Cancer immunology, immunotherapy : CII, 2021, Volume: 70, Issue:2

    Topics: Female; Fingolimod Hydrochloride; Humans; Immune Checkpoint Inhibitors; Immunosuppressive Agents; Lymphocytes; Lymphocytes, Tumor-Infiltrating; Middle Aged; Neoplasms

2021
Potential risk of disease modifying therapies on neoplasm development and coadjutant factors in multiple sclerosis outpatients.
    Scientific reports, 2021, 06-15, Volume: 11, Issue:1

    Topics: Adult; Aged; Alemtuzumab; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Immunosuppressive Agents; Interferon-beta; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Neoplasms; Nitriles; Outpatients; Proportional Hazards Models; Risk Factors; Smoking; Spain; Toluidines

2021
Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.
    Cancer immunology research, 2017, Volume: 5, Issue:11

    Topics: Animals; Cell Line, Tumor; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Interleukin-33; Lymphocytes, Tumor-Infiltrating; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Radiosurgery; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Tumor Burden; Tumor Microenvironment

2017
Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo.
    ACS chemical biology, 2016, Feb-19, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Line, Tumor; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mice, Nude; Neoplasms; Pyrrolidines; Receptors, Lysosphingolipid

2016
Immunosuppressive therapy and post-transplant malignancy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Azathioprine; Calcineurin Inhibitors; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mycophenolic Acid; Neoplasms; Organ Transplantation; Propylene Glycols; Protein Kinases; Sphingosine; TOR Serine-Threonine Kinases

2009
Pharmacological manipulation of the akt signaling pathway regulates myxoma virus replication and tropism in human cancer cells.
    Journal of virology, 2010, Volume: 84, Issue:7

    Topics: Cell Line, Tumor; Fingolimod Hydrochloride; Humans; Intracellular Signaling Peptides and Proteins; Myxoma virus; Neoplasms; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Propylene Glycols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Sphingosine; TOR Serine-Threonine Kinases; Viral Proteins; Viral Tropism; Virus Replication

2010
Tumor masses support naive T cell infiltration, activation, and differentiation into effectors.
    The Journal of experimental medicine, 2010, Aug-02, Volume: 207, Issue:8

    Topics: Adoptive Transfer; Animals; Antigen Presentation; Antigen-Presenting Cells; beta 2-Microglobulin; Carcinoma, Lewis Lung; CD11a Antigen; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell Movement; Cell Proliferation; DNA-Binding Proteins; Fingolimod Hydrochloride; Granzymes; Hyaluronan Receptors; Immunosuppressive Agents; Integrin alpha4; Interferon-gamma; Lymph Nodes; Lymphocyte Activation; Lysosomal Membrane Proteins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monophenol Monooxygenase; Neoplasms; Ovalbumin; Peptide Fragments; Propylene Glycols; Receptors, Antigen, T-Cell; Sphingosine; T-Lymphocyte Subsets

2010
Redirected tumor-specific allogeneic T cells for universal treatment of cancer.
    Blood, 2011, Jul-28, Volume: 118, Issue:4

    Topics: Animals; Antigens, Neoplasm; Cell Separation; Fingolimod Hydrochloride; Flow Cytometry; Graft vs Host Disease; Immunosuppressive Agents; Immunotherapy, Adoptive; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Propylene Glycols; Sphingosine; T-Lymphocytes; Transplantation, Homologous

2011
Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy.
    Current pharmaceutical design, 2006, Volume: 12, Issue:35

    Topics: Amidohydrolases; Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Ceramidases; Ceramides; Enzyme Inhibitors; Fingolimod Hydrochloride; Humans; Lipid Metabolism; Lysophospholipids; Neoplasms; Neovascularization, Pathologic; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine

2006
[mTOR and FTY 720 inhibitors].
    Presse medicale (Paris, France : 1983), 2001, Sep-01, Volume: 30, Issue:24 Pt 2

    Topics: Cyclosporine; Drug Interactions; Drug Therapy, Combination; Everolimus; Fingolimod Hydrochloride; Hyperlipidemias; Immunosuppressive Agents; Kidney; Neoplasms; Propylene Glycols; Sirolimus; Sphingosine

2001