Page last updated: 2024-09-02

fingolimod hydrochloride and Multiple Sclerosis, Chronic Progressive

fingolimod hydrochloride has been researched along with Multiple Sclerosis, Chronic Progressive in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (48.28)24.3611
2020's15 (51.72)2.80

Authors

AuthorsStudies
Kolontareva, YM; Krasnov, VS1
Del Giovane, C; Filippini, G; Kruja, J1
Amato, MP; Battaglia, MA; Brambilla, L; Brescia Morra, V; Capobianco, M; Cavalla, P; Comi, G; De Luca, G; Ferraro, D; Filippi, M; Granella, F; Iaffaldano, P; Lepore, V; Lucisano, G; Lugaresi, A; Lus, G; Malucchi, S; Maniscalco, GT; Manni, A; Moiola, L; Montepietra, S; Mosconi, P; Paolicelli, D; Patti, F; Pesci, I; Petracca, M; Ponzio, M; Ragonese, P; Sola, P; Tedeschi, G; Toscano, S; Totaro, R; Trojano, M; Vianello, M1
Dahlke, F; Häring, DA; Kappos, L; Kropshofer, H; Kuhle, J; Leppert, D; Meinert, R; Patil, A; Tomic, D1
Apóstolos-Pereira, SL; Callegaro, D; Castrillo, BB; Silva, GD1
Aguglia, U; Amato, MP; Angelucci, E; Boffa, G; Brescia Morra, V; Caniatti, LM; Cocco, E; Conte, A; Cottone, S; De Luca, G; Filippi, M; Galgani, S; Gasperini, C; Granella, F; Iaffaldano, P; Inglese, M; Lugaresi, A; Lus, G; Mancardi, GL; Mariottini, A; Massacesi, L; Meletti, S; Moiola, L; Nistri, R; Patti, F; Repice, AM; Romano, S; Saccardi, R; Salemi, G; Sbragia, E; Signori, A; Sola, P; Sormani, MP; Trojano, M; Zaffaroni, M1
Everest, E; Gorkey, OD; Gulec, B; Koc, M; Saip, S; Siva, A; Tutuncu, M; Uygunoglu, U1
Achiron, A; Angelucci, F; Halusková, S; Hartung, HP; Mareš, J; Pavelek, Z; Štourač, P; Tichá, V; Vališ, M1
Cohen, JA; Cree, BAC; Fox, EJ; Kolodny, S; Lublin, FD; Meng, X; Williams, IM; Wolinsky, JS; Ziehn, M1
Asseyer, S; Bäcker-Koduah, P; Berge, T; Boffa, G; Campi, C; Cellerino, M; Harbo, HF; Høgestøl, E; Inglese, M; Ivaldi, F; Kerlero de Rosbo, N; Lapucci, C; Laroni, A; Novi, G; Palmeri, S; Pardini, M; Paul, F; Piana, M; Rotta, G; Sbragia, E; Uccelli, A; Vila, G; Villoslada, P1
Bussone, G; Louapre, C; Lubetzki, C; Maillart, E; Papeix, C; Pourcher, V; Roux, T1
Bowen, JD; Brink, J; Brown, TR; Lucassen, EB; Repovic, P; Smoot, K; Wundes, A1
Azimi, AR; Nourbakhsh, B; Safavi, F1
Diaz, V; Guevara, C; Naves, R; Rosas, CS; Villa, E1
Alvarez, E; Corboy, JR; Nair, K; Sillau, S; Vollmer, BL; Vollmer, T1
Espinosa-Rosso, R; Gil-Bernal, R; Gómez-Gómez, C; González-Caballero, JL1
Chataway, J; Doshi, A1
Hentati, A; Issa, NP1
Akiyuki, U; Kuwabara, S; Masuda, H; Masuda, S; Mori, M; Mutho, M; Tomohiko, U1
Cree, BAC; Freedman, MS; Häring, DA; Hartung, HP; Kappos, L; Li, B; Liu, FC; Lubetzki, C; Lublin, F; Merschhemke, M; Miller, DH; Montalban, X; Putzki, N; Uitdehaag, BMJ; Weiner, H; Wolinsky, JS1
Segal, BM; Stüve, O1
Cohen, JA; Smith, AL1
Ayrignac, X; Cambron, M; Carra, C; Chouraki, A; Davion, JB; Duhin, E; Labauge, P; Lacour, A; Vermersch, P1
Dolgin, E1
Antel, J; Blain, M; Borucki, DM; Chao, CC; de Lima, KA; Healy, L; Kenison, JE; Quintana, FJ; Rothhammer, V; Takenaka, MC; Tjon, E; Wilz, A1
Havla, J; Hohlfeld, R; Kümpfel, T2
Aktas, O; Boyko, A; Hartung, HP; Ingwersen, J; Kieseier, B; Kuery, P1
Comi, G; de Vera, A; Eckert, B; Gold, S; Kappos, L; Montalban, X; O'Connor, P1

Reviews

7 review(s) available for fingolimod hydrochloride and Multiple Sclerosis, Chronic Progressive

ArticleYear
[Siponimod: a new view at the therapy of secondary progressive multiple sclerosis].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:7

    Topics: Azetidines; Benzyl Compounds; Fingolimod Hydrochloride; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive

2021
Rituximab for people with multiple sclerosis.
    The Cochrane database of systematic reviews, 2021, 11-08, Volume: 11

    Topics: Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Rituximab; Young Adult

2021
Is there a role for off-label high-efficacy disease-modifying drugs in progressive multiple sclerosis? A network meta-analysis.
    Acta neurologica Scandinavica, 2022, Volume: 146, Issue:5

    Topics: Azetidines; Benzyl Compounds; Fingolimod Hydrochloride; Humans; Immunologic Factors; Immunosuppressive Agents; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Network Meta-Analysis; Off-Label Use; Rituximab

2022
The Benefits and Risks of Switching from Fingolimod to Siponimod for the Treatment of Relapsing-Remitting and Secondary Progressive Multiple Sclerosis.
    Drugs in R&D, 2023, Volume: 23, Issue:4

    Topics: Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Neurodegenerative Diseases; Recurrence; Risk Assessment

2023
Multiple sclerosis, a treatable disease .
    Clinical medicine (London, England), 2017, Volume: 17, Issue:6

    Topics: Adjuvants, Immunologic; Alemtuzumab; Crotonates; Demyelinating Diseases; Dimethyl Fumarate; Fingolimod Hydrochloride; Glatiramer Acetate; Glucocorticoids; Humans; Hydroxybutyrates; Immunologic Factors; Immunosuppressive Agents; Interferon beta-1a; Interferon beta-1b; Mitoxantrone; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Nitriles; Toluidines

2017
Fingolimod in multiple sclerosis: mechanisms of action and clinical efficacy.
    Clinical immunology (Orlando, Fla.), 2012, Volume: 142, Issue:1

    Topics: Animals; Clinical Trials as Topic; Encephalomyelitis, Autoimmune, Experimental; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis, Chronic Progressive; Propylene Glycols; Sphingosine

2012
[2012: Update on diagnosis and treatment of multiple sclerosis].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:17

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Brain; Combined Modality Therapy; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Fingolimod Hydrochloride; Glatiramer Acetate; Glucocorticoids; Humans; Immunosuppressive Agents; Infusions, Intravenous; Interferon-beta; Methylprednisolone; Mitoxantrone; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Peptides; Plasmapheresis; Propylene Glycols; Pulse Therapy, Drug; Sphingosine; Spinal Cord

2012

Trials

3 trial(s) available for fingolimod hydrochloride and Multiple Sclerosis, Chronic Progressive

ArticleYear
Lymphocyte counts and infection rates: Long-term fingolimod treatment in primary progressive MS.
    Neurology(R) neuroimmunology & neuroinflammation, 2019, Volume: 6, Issue:6

    Topics: Adult; Double-Blind Method; Female; Fingolimod Hydrochloride; Follow-Up Studies; Humans; Immunosuppressive Agents; Infections; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Time Factors

2019
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2016, Mar-12, Volume: 387, Issue:10023

    Topics: Administration, Oral; Adolescent; Adult; Aged; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Treatment Outcome; Young Adult

2016
Oral fingolimod (FTY720) in relapsing multiple sclerosis: impact on health-related quality of life in a phase II study.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2011, Volume: 17, Issue:11

    Topics: Administration, Oral; Adult; Canada; Chi-Square Distribution; Depression; Double-Blind Method; Europe; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Placebos; Propylene Glycols; Psychiatric Status Rating Scales; Quality of Life; Sphingosine; Surveys and Questionnaires; Time Factors; Treatment Outcome

2011

Other Studies

19 other study(ies) available for fingolimod hydrochloride and Multiple Sclerosis, Chronic Progressive

ArticleYear
Risk of Getting COVID-19 in People With Multiple Sclerosis: A Case-Control Study.
    Neurology(R) neuroimmunology & neuroinflammation, 2022, Volume: 9, Issue:2

    Topics: Adult; Age Factors; Case-Control Studies; COVID-19; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunosuppressive Agents; Interferon-beta; Italy; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Odds Ratio; Risk Factors; SARS-CoV-2; Severity of Illness Index; Sex Factors; Time Factors

2022
Blood Neurofilament Light in Progressive Multiple Sclerosis: Post Hoc Analysis of 2 Randomized Controlled Trials.
    Neurology, 2022, 05-24, Volume: 98, Issue:21

    Topics: Acute Disease; Atrophy; Biomarkers; Disease Progression; Fingolimod Hydrochloride; Humans; Intermediate Filaments; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Randomized Controlled Trials as Topic

2022
Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis.
    Neurology, 2023, 03-14, Volume: 100, Issue:11

    Topics: Fingolimod Hydrochloride; Glatiramer Acetate; Hematopoietic Stem Cell Transplantation; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting

2023
Comparison of multiple sclerosis patients with or without rebound activity after fingolimod cessation: Five-year clinical outcomes.
    European journal of neurology, 2023, Volume: 30, Issue:9

    Topics: Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Recurrence

2023
Impact of treatment on cellular immunophenotype in MS: A cross-sectional study.
    Neurology(R) neuroimmunology & neuroinflammation, 2020, Volume: 7, Issue:3

    Topics: Adult; Aged; Cross-Sectional Studies; Disease Progression; Female; Fingolimod Hydrochloride; Flow Cytometry; Germany; Humans; Immunologic Factors; Immunophenotyping; Immunotherapy; Italy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Norway; Spain; Young Adult

2020
Patients with MS treated with immunosuppressive agents: Across the COVID-19 spectrum.
    Revue neurologique, 2020, Volume: 176, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Pandemics; Pneumonia, Viral; SARS-CoV-2

2020
COVID-19 in MS: Initial observations from the Pacific Northwest.
    Neurology(R) neuroimmunology & neuroinflammation, 2020, 09-03, Volume: 7, Issue:5

    Topics: Adult; Aged; Coronavirus Infections; COVID-19; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Immunocompromised Host; Immunosuppressive Agents; Interferons; Lymphopenia; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Nitriles; Northwestern United States; Nursing Homes; Oregon; Pandemics; Pneumonia, Viral; Severity of Illness Index; Toluidines; Travel; Washington

2020
B-cell depleting therapies may affect susceptibility to acute respiratory illness among patients with multiple sclerosis during the early COVID-19 epidemic in Iran.
    Multiple sclerosis and related disorders, 2020, Volume: 43

    Topics: Adult; Antibodies, Monoclonal, Humanized; B-Lymphocytes; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; Cross-Sectional Studies; Crotonates; Dimethyl Fumarate; Disease Susceptibility; Dyspnea; Epidemics; Female; Fever; Fingolimod Hydrochloride; Glatiramer Acetate; Hospitalization; Humans; Hydroxybutyrates; Immunocompromised Host; Immunologic Factors; Intensive Care Units; Interferons; Iran; Lung; Lymphocyte Depletion; Male; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Nitriles; Pandemics; Pneumonia, Viral; Rituximab; SARS-CoV-2; Severity of Illness Index; Toluidines; Tomography, X-Ray Computed

2020
Treating patients with multiple sclerosis during the COVID-19 pandemic: Assessing the expert recommendations.
    Multiple sclerosis and related disorders, 2020, Volume: 43

    Topics: Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chile; Coronavirus Infections; COVID-19; Decision Making; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Guideline Adherence; Guidelines as Topic; Health Behavior; Humans; Immunologic Factors; Interferons; Lymphocyte Count; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Pandemics; Pneumonia, Viral; Quarantine; SARS-CoV-2; World Health Organization; Young Adult

2020
Rituximab versus natalizumab, fingolimod, and dimethyl fumarate in multiple sclerosis treatment.
    Annals of clinical and translational neurology, 2020, Volume: 7, Issue:9

    Topics: Adult; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Follow-Up Studies; Humans; Immunologic Factors; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Outcome Assessment, Health Care; Recurrence; Retrospective Studies; Rituximab

2020
Potential risk of disease modifying therapies on neoplasm development and coadjutant factors in multiple sclerosis outpatients.
    Scientific reports, 2021, 06-15, Volume: 11, Issue:1

    Topics: Adult; Aged; Alemtuzumab; Crotonates; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Immunosuppressive Agents; Interferon-beta; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Neoplasms; Nitriles; Outpatients; Proportional Hazards Models; Risk Factors; Smoking; Spain; Toluidines

2021
VZV encephalitis that developed in an immunized patient during fingolimod therapy.
    Neurology, 2015, Jan-06, Volume: 84, Issue:1

    Topics: Encephalitis, Varicella Zoster; Female; Fingolimod Hydrochloride; Herpes Zoster Vaccine; Humans; Immunocompromised Host; Immunosuppressive Agents; Middle Aged; Multiple Sclerosis, Chronic Progressive; Propylene Glycols; Sphingosine

2015
Change in vital signs after fingolimod initiation in patients with multiple sclerosis: the possible need for 24 h monitoring.
    British journal of clinical pharmacology, 2015, Volume: 80, Issue:3

    Topics: Adolescent; Adult; Drug Monitoring; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Vital Signs; Young Adult

2015
Primary progressive multiple sclerosis--why we are failing.
    Lancet (London, England), 2016, Mar-12, Volume: 387, Issue:10023

    Topics: Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Male; Multiple Sclerosis, Chronic Progressive

2016
Multiple sclerosis: Fingolimod failure in progressive MS INFORMS future trials.
    Nature reviews. Neurology, 2016, Volume: 12, Issue:5

    Topics: Clinical Trials, Phase III as Topic; Disease Progression; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multicenter Studies as Topic; Multiple Sclerosis, Chronic Progressive; Randomized Controlled Trials as Topic; Treatment Failure

2016
Two cases of relapses in primary progressive multiple sclerosis after fingolimod withdrawal.
    Journal of neurology, 2016, Volume: 263, Issue:7

    Topics: Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Recurrence; Substance Withdrawal Syndrome

2016
Therapies: Progressive steps.
    Nature, 2016, 11-30, Volume: 540, Issue:7631

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antigens, CD20; Azetidines; B-Lymphocytes; Benzamides; Benzyl Compounds; Blood-Brain Barrier; Clinical Trials as Topic; Disease Progression; Dogs; Drug Approval; Fingolimod Hydrochloride; Hope; Humans; Male; Mice; Multiple Sclerosis, Chronic Progressive; Neuroprotective Agents; Piperidines; Precision Medicine; Pyridines; Rituximab; Thiazoles; Ubiquinone; United States; United States Food and Drug Administration

2016
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 02-21, Volume: 114, Issue:8

    Topics: Animals; Astrocytes; Cell Line, Tumor; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Microglia; Monocytes; Multiple Sclerosis, Chronic Progressive; Primary Cell Culture; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Transcriptome

2017
[Progress of therapy in patients with multiple sclerosis].
    MMW Fortschritte der Medizin, 2010, Mar-04, Volume: 152, Issue:9

    Topics: 4-Aminopyridine; Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Brain; Cladribine; Clinical Trials as Topic; Fingolimod Hydrochloride; Magnetic Resonance Imaging; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Propylene Glycols; Rituximab; Sphingosine

2010