Page last updated: 2024-09-02

fingolimod hydrochloride and Injury, Ischemia-Reperfusion

fingolimod hydrochloride has been researched along with Injury, Ischemia-Reperfusion in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.44)	18.2507
2000's	18 (43.90)	29.6817
2010's	18 (43.90)	24.3611
2020's	4 (9.76)	2.80

Authors

Authors	Studies
Ahmadian, E; Ardalan, M; Bagheri, Y; Hejazian, SM; Raeesi, M; Zununi Vahed, S	1
Ahmed, N	1
Chen, H; Han, M; Sun, T; Wang, D	1
Kang, DL; Li, TT; Shi, ZA; Su, H; Tu, FP	1
Chen, H; Chen, Q; Chu, Y; Guo, Q; Jiang, C; Li, C; Li, X; Liu, P; Luo, Y; Ning, T; Song, H; Su, B; Sun, T; Wang, Y; You, H; Zhang, T; Zhang, Y; Zhao, Z; Zhou, W; Zhou, Z	1
Campbell, B; Lin, L; Lou, M; Shi, FD; Zhang, M; Zhang, R; Zhang, S; Zhou, Y	1
Chen, F; Lin, L; Pan, Y; Wang, L; Xiong, X	1
Bradley, MJ; Clark, N; Davis, TA; Elster, EA; Foster, AD; Leonhardt, C; Vicente, D	1
Brait, VH; Chamorro, A; Gallizioli, M; Justicia, C; Meissner, A; Miró-Mur, F; Planas, AM; Salas-Perdomo, A; Urra, X	1
Honbo, N; Imhof, I; Karliner, JS; Li, L; Vessey, DA	1
Egom, EE; Kruzliak, P; Lei, M; Rotrekl, V	1
Charles, EJ; Huerter, ME; Johnston, WF; Kron, IL; Laubach, VE; Lynch, KR; Sharma, AK; Stone, ML; Zhao, Y	1
Butts, M; Edison, J; Frattalone, S; Moratz, CM; Tracy, C; Woodard, GE	1
Brait, VH; Gavaldà, A; Godessart, N; Planas, AM; Tarrasón, G	1
Awad, AS; Bajwa, A; Jo, SK; Kharel, Y; Lynch, KR; Okusa, MD; Vergis, AL; Ye, H	1
Gidday, JM; Park, TS; Wacker, BK	1
Cartwright, E; Egom, EE; Ke, Y; Lei, M; Mohamed, TM; Musa, H; Solaro, RJ; Wang, T	1
Dragun, D; Fuller, TF; Hegner, B; Hoff, U; Kong, L; Luft, FC; Naether, M; Nieminen-Kelhä, M; Nolting, J; Wagner, P	1
Bajwa, A; Dondeti, KR; Haase, VH; Huang, L; Jo, SK; Lynch, KR; Macdonald, TL; Okusa, MD; Rosin, DL; Ye, H	1
Cho, WY; Jo, SK; Kim, HK; Kim, MG; Ko, YS; Lee, HY; Lee, SY	1
Fiedler, M; Martin, M; Mory, C; Prescher, A; Uhlmann, D	1
Bueno, V; Franco, M; Gomes, GN; Haidar, AA; Hirata, AE; Pedregosa, JF	1
Domínguez, J; Giacaman, A; Lira, F; Mendez, G	1
Fan, ST; Geng, W; Li, CX; Ling, CC; Liu, XB; Lo, CM; Ma, YY; Man, K; Ng, KT; Shao, Y	1
Amersi, FF; Anselmo, D; Brinkmann, V; Busuttil, RW; Coito, AJ; Farmer, DG; Gao, F; Katori, M; Ke, B; Kupiec-Weglinski, JW; Lassman, C; Shen, XD	1
Amersi, FF; Anselmo, DM; Brinkmann, V; Busuttil, RW; Coito, AJ; Farmer, DG; Gao, F; Katori, M; Ke, B; Kupiec-Weglinski, JW; Lassman, C; Ma, J; Shen, XD	1
Kahan, BD; Ortiz, AM; Troncoso, P	1
Aki, FT; Kahan, BD	1
Böhler, T; Budde, K; Dragun, D; Haller, H; Luft, FC; Neumayer, HH; Nieminen-Kelhä, M; Schneider, W; Waiser, J	1
Borra, RC; Bueno, V; Franco, M; Oliveira, CM; Pestana, JO; Schor, N; Silva, HT	1
Fan, ST; Ho, JW; Lee, TK; Li, XL; Lo, CM; Man, K; Ng, KT; Sun, CK; Zhao, Y	1
Domínguez, J; Kahan, BD; Ortiz, AM; Troncoso, P	1
Awad, AS; Foss, FW; Huang, L; Li, L; Lynch, KR; Macdonald, TL; Okusa, MD; Ye, H	1
Bergmann, S; Frink, M; Kaudel, CP; Klempnauer, J; Krettek, C; Pape, HC; Schmiddem, U; Winkler, M	1
Bergmann, S; Frink, M; Kaudel, CP; Klempnauer, J; Krettek, C; Probst, C; Schmiddem, U; van Griensven, M; Winkler, M	2
Delbridge, MS; El Nahas, AM; Haylor, JL; Raftery, AT; Shrestha, BM	1
Frink, M; Hildebrand, F; Kaudel, CP; Klempnauer, J; Krettek, C; Pape, HC; van Griensven, M; Winkler, M	1
Bueno, V; Cury, PM; da Silva, LB; Palma, PV	1
Delbridge, MS; El Nahas, AM; Haylor, J; Raftery, AT; Shrestha, BM	1
Fujimura, A; Hashizume, K; Kanno, T; Kitoh, Y; Kobayashi, E; Miyashita, F; Mizuta, K; Mori, M; Ohmori, M	1

Reviews

3 review(s) available for fingolimod hydrochloride and Injury, Ischemia-Reperfusion

Article	Year
Cardioprotective mechanism of FTY720 in ischemia reperfusion injury. Journal of basic and clinical physiology and pharmacology, 2019, Aug-30, Volume: 30, Issue:5 Topics: Animals; Cardiotonic Agents; Fingolimod Hydrochloride; Humans; Models, Biological; Reperfusion Injury	2019
Potential sphingosine-1-phosphate-related therapeutic targets in the treatment of cerebral ischemia reperfusion injury. Life sciences, 2020, May-15, Volume: 249 Topics: Animals; Brain; Fingolimod Hydrochloride; Humans; Lysophospholipids; Reperfusion Injury; Sphingosine; Sphingosine-1-Phosphate Receptors	2020
FTY720: A new kid on the block for transplant immunosuppression. Expert opinion on biological therapy, 2003, Volume: 3, Issue:4 Topics: Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dogs; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Infections; Mice; Primates; Propylene Glycols; Rats; Reperfusion Injury; Sphingosine; Transplantation Immunology; Transplantation, Heterologous	2003

Trials

1 trial(s) available for fingolimod hydrochloride and Injury, Ischemia-Reperfusion

Article	Year
Rationale and design of combination of an immune modulator Fingolimod with Alteplase bridging with Mechanical Thrombectomy in Acute Ischemic Stroke (FAMTAIS) trial. International journal of stroke : official journal of the International Stroke Society, 2017, Volume: 12, Issue:8 Topics: Brain Ischemia; Combined Modality Therapy; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mechanical Thrombolysis; Reperfusion Injury; Research Design; Stroke; Time-to-Treatment; Tissue Plasminogen Activator	2017

Article

Year

Rationale and design of combination of an immune modulator Fingolimod with Alteplase bridging with Mechanical Thrombectomy in Acute Ischemic Stroke (FAMTAIS) trial.

International journal of stroke : official journal of the International Stroke Society, 2017, Volume: 12, Issue:8

Topics: Brain Ischemia; Combined Modality Therapy; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mechanical Thrombolysis; Reperfusion Injury; Research Design; Stroke; Time-to-Treatment; Tissue Plasminogen Activator

2017

Other Studies

37 other study(ies) available for fingolimod hydrochloride and Injury, Ischemia-Reperfusion

Article	Year
The Effect of Fingolimod on Renal Ischemia/Reperfusion Injury in a Rat Model. Current molecular pharmacology, 2024, Volume: 17, Issue:1 Topics: Acute Kidney Injury; Animals; Antioxidants; Fingolimod Hydrochloride; Glutathione; Glutathione Peroxidase; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion Injury	2024
Fingolimod attenuates renal ischemia/reperfusion-induced acute lung injury by inhibiting inflammation and apoptosis and modulating S1P metabolism. The Journal of international medical research, 2021, Volume: 49, Issue:8 Topics: Acute Lung Injury; Animals; Apoptosis; Fingolimod Hydrochloride; Inflammation; Ischemia; Lysophospholipids; Rats; Reperfusion; Reperfusion Injury; Sphingosine	2021
Macrophage-Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:20 Topics: Animals; Cell Line, Tumor; Cellular Microenvironment; Fingolimod Hydrochloride; Humans; Hydrogen Peroxide; Inflammation; Ischemic Stroke; Lysosomes; Macrophages; Manganese Compounds; Nanoparticles; Nanospheres; Neurons; Neuroprotection; Oxidative Stress; Oxides; Oxygen; Primary Cell Culture; Rats; Reperfusion Injury	2021
Effects of FTY720 on Lung Injury Induced by Hindlimb Ischemia Reperfusion in Rats. Mediators of inflammation, 2017, Volume: 2017 Topics: Animals; Blood Gas Analysis; Fingolimod Hydrochloride; Hindlimb; Immunosuppressive Agents; Lung Injury; Male; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger	2017
FTY720 Effects on Inflammation and Liver Damage in a Rat Model of Renal Ischemia-Reperfusion Injury. Mediators of inflammation, 2019, Volume: 2019 Topics: Animals; Disease Models, Animal; Fingolimod Hydrochloride; Inflammation; Kidney; Kidney Diseases; Liver; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Transcription Factor AP-1	2019
Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke. Scientific reports, 2019, 06-05, Volume: 9, Issue:1 Topics: Animals; Brain; Brain Ischemia; Fingolimod Hydrochloride; Hemoglobins; Hemorrhage; Lymphocytes; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Reperfusion Injury; RNA, Messenger; Sphingosine; Sphingosine 1 Phosphate Receptor Modulators; Sphingosine-1-Phosphate Receptors; Stroke; T-Lymphocytes; Thrombocytopenia; Up-Regulation	2019
FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning. Medical science monitor basic research, 2013, Apr-09, Volume: 19 Topics: Adenosine; Algorithms; Animals; Fingolimod Hydrochloride; Immunosuppressive Agents; In Vitro Techniques; Ischemic Postconditioning; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Perfusion; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Reperfusion Injury; Sphingosine	2013
The effect of the sphingosine-1-phosphate analogue FTY720 on atrioventricular nodal tissue. Journal of cellular and molecular medicine, 2015, Volume: 19, Issue:7 Topics: Animals; Atrioventricular Node; Dissection; Fingolimod Hydrochloride; Gene Expression Regulation; Lysophospholipids; Rats; Receptors, Lysosphingolipid; Reperfusion Injury; RNA, Messenger; Sphingosine	2015
Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. American journal of physiology. Lung cellular and molecular physiology, 2015, Jun-15, Volume: 308, Issue:12 Topics: Animals; Bronchoalveolar Lavage Fluid; Cyclopentanes; Cytokines; Fingolimod Hydrochloride; Flow Cytometry; Immunoenzyme Techniques; Immunosuppressive Agents; Lung Injury; Lysophospholipids; Mice; Mice, Inbred C57BL; Propylene Glycols; Receptors, Lysosphingolipid; Reperfusion Injury; Sphingosine; Sphingosine-1-Phosphate Receptors	2015
Inhibition of Sphingosine-1-phosphate receptors in ischemia reperfusion injured autoimmunity-prone mice. Cellular immunology, 2017, Volume: 311 Topics: Animals; Autoimmunity; Blood Vessels; CD4-Positive T-Lymphocytes; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Susceptibility; Fingolimod Hydrochloride; Gene Expression Regulation; Humans; Immunosuppressive Agents; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Neutrophils; Receptors, Lysosphingolipid; Reperfusion Injury; Sphingosine-1-Phosphate Receptors	2017
Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. Stroke, 2016, Volume: 47, Issue:12 Topics: Animals; Cerebral Infarction; Fingolimod Hydrochloride; Immunosuppressive Agents; Lymphopenia; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Receptors, Lysosphingolipid; Reperfusion Injury; Sphingosine	2016
Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury. Kidney international, 2009, Volume: 75, Issue:2 Topics: Animals; Fingolimod Hydrochloride; Gene Expression Regulation, Enzymologic; Kidney; Kidney Diseases; Lysophospholipids; Mice; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Reperfusion Injury; RNA, Messenger; Sphingosine	2009
Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2. Stroke, 2009, Volume: 40, Issue:10 Topics: Animals; Arterioles; Brain Edema; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Fingolimod Hydrochloride; Hypoxia-Ischemia, Brain; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Lysophospholipids; Male; Mice; Microcirculation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Reperfusion Injury; RNA, Messenger; Sphingosine	2009
FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling. Journal of molecular and cellular cardiology, 2010, Volume: 48, Issue:2 Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Disease Models, Animal; Enzyme Activation; Fingolimod Hydrochloride; Gene Expression Regulation; In Vitro Techniques; Intracellular Space; Male; p21-Activated Kinases; Pertussis Toxin; Phosphorylation; Propylene Glycols; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Reperfusion Injury; RNA, Messenger; Signal Transduction; Sinoatrial Node; Sphingosine; Time Factors; Ultrasonography	2010
Cytoprotective Actions of FTY720 Modulate Severe Preservation Reperfusion Injury in Rat Renal Transplants. Transplantation, 2010, Feb-27, Volume: 89, Issue:4 Topics: Adenosine; Allopurinol; Animals; Cell Culture Techniques; Cell Division; Cell Survival; Fingolimod Hydrochloride; Flow Cytometry; Glutathione; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Insulin; Kidney Transplantation; Male; Organ Preservation Solutions; Propylene Glycols; Raffinose; Rats; Rats, Inbred Lew; Reperfusion Injury; Sphingosine	2010
Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury. Journal of the American Society of Nephrology : JASN, 2010, Volume: 21, Issue:6 Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Movement; Disease Models, Animal; Epithelial Cells; Fingolimod Hydrochloride; Homeodomain Proteins; Kidney Tubules, Proximal; Leukocytes; Lipopolysaccharides; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Oxadiazoles; Propylene Glycols; Receptors, Lysosphingolipid; Reperfusion Injury; RNA, Messenger; Signal Transduction; Sphingosine; Thiophenes	2010
CD4+ CD25+ regulatory T cells partially mediate the beneficial effects of FTY720, a sphingosine-1-phosphate analogue, during ischaemia/reperfusion-induced acute kidney injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:1 Topics: Acute Kidney Injury; Animals; CD4-Positive T-Lymphocytes; Dendritic Cells; Fingolimod Hydrochloride; Flow Cytometry; Forkhead Transcription Factors; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Kidney; Lymphocyte Culture Test, Mixed; Lymphopenia; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Propylene Glycols; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Spleen; T-Lymphocytes, Regulatory	2011
Effect of FTY720 treatment on postischemic pancreatic microhemodynamics. Transplantation proceedings, 2010, Volume: 42, Issue:10 Topics: Animals; Female; Fingolimod Hydrochloride; Hemodynamics; Immunosuppressive Agents; Propylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Sphingosine	2010
TLR2 and TLR4 expression after kidney ischemia and reperfusion injury in mice treated with FTY720. International immunopharmacology, 2011, Volume: 11, Issue:9 Topics: Animals; Creatinine; Fingolimod Hydrochloride; Interleukin-6; Kidney; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Propylene Glycols; Reperfusion Injury; Sphingosine; Spleen; Toll-Like Receptor 2; Toll-Like Receptor 4; Urea	2011
Short-term immunossupressive treatment of the donor does not prevent ischemia-reperfusion kidney damage in the rat. Transplantation proceedings, 2011, Volume: 43, Issue:9 Topics: Animals; Cadaver; Creatinine; Fingolimod Hydrochloride; Graft Survival; Hypertonic Solutions; Immunosuppressive Agents; Kidney Transplantation; Male; Propylene Glycols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus; Sphingosine; Tissue Donors	2011
FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells. PloS one, 2012, Volume: 7, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; Liver; Liver Neoplasms; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Propylene Glycols; Rats; Reperfusion Injury; Sphingosine; Stem Cells; Time Factors	2012
FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injury. Transplantation proceedings, 2002, Volume: 34, Issue:5 Topics: Animals; Fingolimod Hydrochloride; Immunosuppressive Agents; Liver; Liver Circulation; Lymphocyte Count; Peroxidase; Propylene Glycols; Rats; Rats, Inbred Lew; Reperfusion Injury; Sphingosine	2002
FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2002, Volume: 2, Issue:9 Topics: Animals; Cell Movement; Fingolimod Hydrochloride; Immunohistochemistry; Immunosuppressive Agents; Liver; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Reperfusion Injury; Sphingosine; T-Lymphocytes	2002
Prevention of renal ischemic reperfusion injury using FTY 720 and ICAM-1 antisense oligonucleotides. Transplantation proceedings, 2003, Volume: 35, Issue:4 Topics: Analysis of Variance; Animals; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Kidney Transplantation; Male; Oligonucleotides, Antisense; Propylene Glycols; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Sphingosine; Thionucleotides; Transplantation, Isogeneic	2003
FTY720-induced lymphocyte homing modulates post-transplant preservation/reperfusion injury. Kidney international, 2004, Volume: 65, Issue:3 Topics: Animals; Cell Movement; Fingolimod Hydrochloride; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Lymphocyte Subsets; Male; Propylene Glycols; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reperfusion Injury; Sphingosine	2004
FTY720 impairs necrosis development after ischemia-reperfusion injury. Transplantation proceedings, 2004, Volume: 36, Issue:4 Topics: Analysis of Variance; Animals; Creatinine; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Liver; Mice; Necrosis; Propylene Glycols; Reperfusion Injury; Sphingosine; Urea	2004
FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:1 Topics: Animals; Apoptosis; Blotting, Western; Chemokine CXCL2; Chemokines, CXC; DNA Primers; Down-Regulation; Endothelin-1; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Fingolimod Hydrochloride; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; In Situ Nick-End Labeling; Inflammation; Intercellular Signaling Peptides and Proteins; Interleukin-10; Liver; Male; MAP Kinase Signaling System; Microscopy, Electron; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Propylene Glycols; Proteins; raf Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sphingosine; Time Factors; Up-Regulation	2005
Use of FTY 720 and ICAM-1 antisense oligonucleotides for attenuating chronic renal damage secondary to ischemia-reperfusion injury. Transplantation proceedings, 2005, Volume: 37, Issue:10 Topics: Animals; Disease Models, Animal; Fingolimod Hydrochloride; Intercellular Adhesion Molecule-1; Inulin; Kidney; Kidney Function Tests; Male; Oligonucleotides, Antisense; Propylene Glycols; Rats; Rats, Inbred Lew; Reperfusion Injury; Sphingosine	2005
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6 Topics: Animals; Capillary Permeability; Creatinine; Fingolimod Hydrochloride; Kidney; Leukocytes; Lymphocyte Count; Mice; Mice, Inbred C57BL; Oxadiazoles; Peroxidase; Propylene Glycols; Receptors, Lysosphingolipid; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; T-Lymphocytes; Thiophenes	2006
FTY720 for treatment of ischemia-reperfusion injury following complete renal ischemia in C57/BL6 mice. Transplantation proceedings, 2006, Volume: 38, Issue:3 Topics: Animals; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Injections, Intraperitoneal; Ischemia; Male; Mice; Mice, Inbred C57BL; Propylene Glycols; Renal Circulation; Reperfusion Injury; Sphingosine	2006
FTY720 application following isolated warm liver ischemia improves long-term survival and organ protection in a mouse model. Transplantation proceedings, 2007, Volume: 39, Issue:2 Topics: Animals; Fingolimod Hydrochloride; Immunosuppressive Agents; Liver; Male; Mice; Mice, Inbred C57BL; Models, Animal; Propylene Glycols; Reperfusion Injury; Sphingosine; Survival Analysis; Time Factors	2007
FTY720 for treatment of ischemia-reperfusion injury following complete renal ischemia; impact on long-term survival and T-lymphocyte tissue infiltration. Transplantation proceedings, 2007, Volume: 39, Issue:2 Topics: Animals; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Propylene Glycols; Renal Circulation; Reperfusion Injury; Sphingosine; Survival Analysis; T-Lymphocytes	2007
Reduction of ischemia-reperfusion injury in the rat kidney by FTY720, a synthetic derivative of sphingosine. Transplantation, 2007, Jul-27, Volume: 84, Issue:2 Topics: Animals; Apoptosis; Cell Proliferation; Creatinine; Disease Models, Animal; Fingolimod Hydrochloride; Flow Cytometry; Follow-Up Studies; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Proliferating Cell Nuclear Antigen; Propylene Glycols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sphingosine; Treatment Outcome	2007
FTY720 improves survival after transient ischemia and reperfusion of the hind limbs. The Journal of trauma, 2007, Volume: 63, Issue:2 Topics: Analysis of Variance; Animals; Biomarkers; Cytokines; Disease Models, Animal; Fingolimod Hydrochloride; Hindlimb; Immunosuppressive Agents; Interleukin-1; Ischemia; Male; Mice; Mice, Inbred C57BL; Peroxidase; Probability; Propylene Glycols; Random Allocation; Reference Values; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Sphingosine; Survival Rate	2007
Evaluation of stem cell administration in a model of kidney ischemia-reperfusion injury. International immunopharmacology, 2007, Dec-15, Volume: 7, Issue:13 Topics: Animals; Creatinine; Disease Models, Animal; Fingolimod Hydrochloride; Hematopoietic Stem Cell Transplantation; Kidney; Male; Mice; Mice, Inbred C57BL; Necrosis; Propylene Glycols; Reperfusion Injury; Sphingosine	2007
FTY720 reduces extracellular matrix expansion associated with ischemia-reperfusion induced injury. Transplantation proceedings, 2007, Volume: 39, Issue:10 Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Extracellular Matrix; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney Transplantation; Male; Propylene Glycols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sphingosine; Transplantation, Homologous	2007
Effect of pretreatment with FTY720 and cyclosporin on ischaemia-reperfusion injury of the liver in rats. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:12 Topics: Animals; Cyclosporine; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Leukocytes, Mononuclear; Liver; Male; Neutrophil Activation; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Sphingosine; Transaminases; Tumor Necrosis Factor-alpha	1999