Page last updated: 2024-09-02

fingolimod hydrochloride and Injuries, Spinal Cord

fingolimod hydrochloride has been researched along with Injuries, Spinal Cord in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's5 (55.56)2.80

Authors

AuthorsStudies
Azedi, F; Poormoghadam, D; Rezayat, SM; Shiadeh, BR; Tavakol, H; Tavakol, S1
Houkin, K; Kawabori, M; Konno, K; Seki, T; Takamiya, S; Tateno, T; Watanabe, M; Yamazaki, K1
Wang, H; Zhang, L1
Aligholi, H; Alipour, H; Azari, H; Mahdavipour, M; Mirzaei, E; Nami, M; Sarkoohi, P; Torabi, S; Zeraatpisheh, Z1
Chen, J; Lai, X; Li, S; Li, Z; Xia, Q; Zhang, C1
Cai, Y; Heng, BC; Hong, L; Liu, H; Lu, P; Ouyang, H; Ren, H; Wang, J; Wang, Y; Zhou, J1
Chow, WN; Colello, RJ; Graf, MR; Graham, RS; Lee, KD; Mathern, BE; Sato-Bigbee, C; Young, HF1
Cao, X; Sun, Y; Zhang, A; Zhang, J; Zhang, N1
Hoshino, Y; Kimura, A; Madoiwa, S; Mimuro, J; Norimatsu, Y; Ohmori, T; Sakata, Y; Seichi, A; Yatomi, Y1

Reviews

1 review(s) available for fingolimod hydrochloride and Injuries, Spinal Cord

ArticleYear
FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential.
    Brain research bulletin, 2020, Volume: 164

    Topics: Animals; Apoptosis; Autophagy; Brain Injuries; Fingolimod Hydrochloride; Neuroprotective Agents; Oxidative Stress; Spinal Cord Injuries

2020

Other Studies

8 other study(ies) available for fingolimod hydrochloride and Injuries, Spinal Cord

ArticleYear
Fingolimod Nanoemulsions at Different Particle Sizes Define the Fate of Spinal Cord Injury Recovery.
    BioMed research international, 2022, Volume: 2022

    Topics: Animals; Delayed-Action Preparations; Endothelial Cells; Fingolimod Hydrochloride; Particle Size; Rats; Spinal Cord; Spinal Cord Injuries

2022
FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model.
    Journal of neurotrauma, 2020, 08-01, Volume: 37, Issue:15

    Topics: Animals; Female; Fingolimod Hydrochloride; Inflammation; Injections, Intraperitoneal; Neuralgia; Rats; Rats, Sprague-Dawley; Sphingosine 1 Phosphate Receptor Modulators; Spinal Cord Compression; Spinal Cord Injuries; Thoracic Vertebrae

2020
Local delivery of fingolimod through PLGA nanoparticles and PuraMatrix-embedded neural precursor cells promote motor function recovery and tissue repair in spinal cord injury.
    The European journal of neuroscience, 2021, Volume: 54, Issue:4

    Topics: Animals; Cell Differentiation; Fingolimod Hydrochloride; Glycols; Mice; Nanoparticles; Neural Stem Cells; Peptides; Recovery of Function; Spinal Cord Injuries

2021
Exosomes Derived from Nerve Stem Cells Loaded with FTY720 Promote the Recovery after Spinal Cord Injury in Rats by PTEN/AKT Signal Pathway.
    Journal of immunology research, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Disease Models, Animal; Endothelial Cells; Exosomes; Fingolimod Hydrochloride; Humans; Male; Neural Stem Cells; Neurons; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine 1 Phosphate Receptor Modulators; Spinal Cord; Spinal Cord Injuries

2021
Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis.
    Biomaterials, 2015, Volume: 62

    Topics: Administration, Topical; Animals; Delayed-Action Preparations; Fingolimod Hydrochloride; Gliosis; Immunosuppressive Agents; Lysophospholipids; Male; Membranes, Artificial; Polyesters; Rats; Rats, Sprague-Dawley; Recovery of Function; Sphingosine; Spinal Cord Injuries; Treatment Outcome

2015
FTY720 reduces inflammation and promotes functional recovery after spinal cord injury.
    Journal of neurotrauma, 2009, Volume: 26, Issue:12

    Topics: Animals; Autoimmunity; Chemotaxis, Leukocyte; Demyelinating Autoimmune Diseases, CNS; Disease Models, Animal; Fingolimod Hydrochloride; Flow Cytometry; Immunosuppressive Agents; Lymphocyte Activation; Myelitis; Nerve Fibers, Myelinated; Nerve Regeneration; Paralysis; Propylene Glycols; Rats; Rats, Long-Evans; Recovery of Function; Sphingosine; Spinal Cord Injuries; T-Lymphocytes; Treatment Outcome; Urinary Bladder, Neurogenic; Wallerian Degeneration

2009
Treatment with immunosuppressants FTY720 and tacrolimus promotes functional recovery after spinal cord injury in rats.
    The Tohoku journal of experimental medicine, 2009, Volume: 219, Issue:4

    Topics: Animals; Axons; Evoked Potentials, Somatosensory; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Myelin Sheath; Propylene Glycols; Rats; Rats, Sprague-Dawley; Recovery of Function; Sphingosine; Spinal Cord Injuries; Tacrolimus

2009
FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms.
    The American journal of pathology, 2012, Volume: 180, Issue:4

    Topics: Animals; Astrocytes; Capillary Permeability; Cell Movement; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Locomotion; Mice; Mice, Inbred C57BL; Mice, SCID; Microglia; Neutrophils; Propylene Glycols; Receptors, Lysosphingolipid; Recovery of Function; Sphingosine; Spinal Cord Injuries; T-Lymphocytes; Treatment Outcome

2012