Page last updated: 2024-09-02

fingolimod hydrochloride and Infarction, Middle Cerebral Artery

fingolimod hydrochloride has been researched along with Infarction, Middle Cerebral Artery in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's5 (41.67)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Fu, Y; Li, S; Lin, K; Lv, A; Tian, L; Wang, Z; Yan, Y; Zhao, W1
Sui, R; Zhang, L1
Arai, K; Esposito, E; Lee, J; Li, W; Lizasoain, I; Lo, EH; Mandeville, ET; Mandeville, JB; Moro, MÁ; Nakano, T; Park, JH; Quinto-Alemany, D; Waeber, C; Zhang, F1
Choi, JW; Gaire, BP1
Chen, CP; Chew, WS; Chua, XY; Herr, DR; Ho, LTY; Lai, MKP; Lam, BWS; Ong, WY; Xiang, P1
Altay, O; Hasegawa, Y; Rolland, W; Suzuki, H; Zhang, JH1
Haghani, M; Keshavarz, S; Namavar, MR; Nazari, M; Rafati, A1
Fluri, F; Kleinschnitz, C; Krstic, M; Schuhmann, MK1
Gidday, JM; Park, TS; Wacker, BK1
Friedlander, RM; Lin, N1
Hasegawa, Y; Rolland, W; Sozen, T; Suzuki, H; Zhang, JH1
Czech-Zechmeister, B; Foerch, C; Huwiler, A; Koch, A; Mirceska, A; Pfeilschifter, J; Pfeilschifter, W; Rami, A; Steinmetz, H; Sujak, M1

Reviews

2 review(s) available for fingolimod hydrochloride and Infarction, Middle Cerebral Artery

ArticleYear
Sphingosine 1-Phosphate Receptors in Cerebral Ischemia.
    Neuromolecular medicine, 2021, Volume: 23, Issue:1

    Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Stroke; Lysophospholipids; Neovascularization, Physiologic; Nerve Tissue Proteins; Neuroprotective Agents; Phosphotransferases (Alcohol Group Acceptor); Rats; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors

2021
Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment.
    Neuromolecular medicine, 2021, Volume: 23, Issue:1

    Topics: Aldehyde-Lyases; Alzheimer Disease; Animals; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia, Vascular; Drug Delivery Systems; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Stroke; Lysophospholipids; Mice; Mice, Knockout; Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors

2021

Other Studies

10 other study(ies) available for fingolimod hydrochloride and Infarction, Middle Cerebral Artery

ArticleYear
USPIO-SWI Shows Fingolimod Enhanced Alteplase Action on Angiographic Reperfusion in eMCAO Rats.
    Journal of magnetic resonance imaging : JMRI, 2022, Volume: 55, Issue:4

    Topics: Animals; Contrast Media; Dextrans; Embolism; Fingolimod Hydrochloride; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Rats; Reperfusion; Stroke; Tissue Plasminogen Activator

2022
Fingolimod protects against cerebral ischemia reperfusion injury in rats by reducing inflammatory cytokines and inhibiting the activation of p38 MAPK and NF-κB signaling pathways.
    Neuroscience letters, 2022, 02-06, Volume: 771

    Topics: Animals; Cerebral Cortex; Fingolimod Hydrochloride; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Interleukins; Male; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha

2022
Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases.
    Stroke, 2022, Volume: 53, Issue:12

    Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Fingolimod Hydrochloride; Hemorrhage; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Sphingosine; Stroke

2022
Role of the sphingosine metabolism pathway on neurons against experimental cerebral ischemia in rats.
    Translational stroke research, 2013, Volume: 4, Issue:5

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; Neurons; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Rats; Rats, Sprague-Dawley; Sphingosine

2013
Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia.
    Brain research bulletin, 2016, Volume: 124

    Topics: Animals; Avoidance Learning; Brain Infarction; Disease Models, Animal; Fingolimod Hydrochloride; Hippocalcin; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Lymphocytes; Male; Memory Disorders; Neurologic Examination; Neuronal Plasticity; Neutrophils; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors

2016
Fingolimod (FTY720) Reduces Cortical Infarction and Neurological Deficits During Ischemic Stroke Through Potential Maintenance of Microvascular Patency.
    Current neurovascular research, 2016, Volume: 13, Issue:4

    Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Fingolimod Hydrochloride; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Microvessels; Stroke

2016
Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Animals; Arterioles; Brain Edema; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Fingolimod Hydrochloride; Hypoxia-Ischemia, Brain; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Lysophospholipids; Male; Mice; Microcirculation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Reperfusion Injury; RNA, Messenger; Sphingosine

2009
T-cell activation in ischemic stroke: a new therapeutic target for delayed infarct expansion?
    Neurosurgery, 2009, Volume: 65, Issue:6

    Topics: Animals; Brain Infarction; Cytokines; Disease Models, Animal; Fingolimod Hydrochloride; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Interleukin-17; Interleukin-23; Mice; Mice, Knockout; Propylene Glycols; Sphingosine; T-Lymphocytes

2009
Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.
    Stroke, 2010, Volume: 41, Issue:2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Fingolimod Hydrochloride; Immunosuppressive Agents; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Nerve Degeneration; Neuroprotective Agents; Oxadiazoles; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Stroke; Thiophenes; Treatment Outcome

2010
Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia.
    Biochemical and biophysical research communications, 2011, Sep-23, Volume: 413, Issue:2

    Topics: Animals; Brain Ischemia; Enzyme Activation; Fingolimod Hydrochloride; Gene Deletion; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Sphingosine

2011