fingolimod hydrochloride has been researched along with Diabetes Mellitus, Type 1 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, LL; Liu, H; Pan, LL; Sun, J; Zhang, M | 1 |
| Akin, M; Arndt, T; Hedrich, HJ; Jörns, A; Lenzen, S; Terbish, T; Wedekind, D; Zu Vilsendorf, AM | 1 |
| Bluestone, JA; Penaranda, C; Ruddle, NH; Tang, Q | 1 |
| Arndt, T; Hedrich, HJ; Jörns, A; Lenzen, S; Meyer Zu Vilsendorf, A; Rath, KJ; Terbish, T; Wedekind, D | 1 |
| Ley, K; McDuffie, M; Morris, MA; Nadler, JL | 1 |
| Ayala-Perez, R; Fynch, S; Graham, KL; Kay, TW; Krishnamurthy, B; Santamaria, P; Slattery, RM; Thomas, HE | 1 |
| Chen, X; Li, J; Lu, Y; Wan, H; Ye, S; Zhang, S; Zheng, G; Zhu, H | 1 |
| Gottschalk, R; Maki, T; Monaco, AP | 1 |
| Brinkmann, V; Chen, M; Ellett, JD; Fialkow, LB; Lynch, KR; Nadler, JL; Wu, R; Yang, Z | 1 |
| Kover, KL; Moore, WV; Popovic, J | 1 |
| Gottschalk, R; Maki, T; Monaco, AP; Ogawa, N | 1 |
| Amemiya, H; Hiromitsu, K; Li, XK; Suzuki, K; Suzuki, S; Yan, H | 2 |
| Brinkmann, V; Chen, S; Feng, L; Pinschewer, DD | 1 |
1 review(s) available for fingolimod hydrochloride and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
FTY720: altered lymphocyte traffic results in allograft protection.
Topics: Animals; Autoimmune Diseases; Cell Movement; Chemokines; Clinical Trials as Topic; Cyclosporine; Diabetes Mellitus, Type 1; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Humans; Immunologic Memory; Immunosuppressive Agents; Inflammation; Islets of Langerhans Transplantation; Lymphocyte Activation; Lymphocytes; Models, Animal; Propylene Glycols; Safety; Sphingosine; Transplantation, Homologous | 2001 |
13 other study(ies) available for fingolimod hydrochloride and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Early-life fingolimod treatment improves intestinal homeostasis and pancreatic immune tolerance in non-obese diabetic mice.
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Movement; Diabetes Mellitus, Type 1; Dysbiosis; Female; Fingolimod Hydrochloride; Gastrointestinal Microbiome; Homeostasis; Hypoglycemic Agents; Immune Tolerance; Intestines; Mice, Inbred NOD; Pancreas; Signal Transduction | 2021 |
Anti-TCR therapy combined with fingolimod for reversal of diabetic hyperglycemia by β cell regeneration in the LEW.1AR1-iddm rat model of type 1 diabetes.
Topics: Animals; Antibodies; Cell Proliferation; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Animal; Drug Therapy, Combination; Fingolimod Hydrochloride; Hyperglycemia; Immunosuppressive Agents; Insulin-Secreting Cells; Lymph Nodes; Macrophages; Microscopy, Electron, Transmission; Propylene Glycols; Rats; Receptors, Antigen, T-Cell; Sphingosine; T-Lymphocytes | 2014 |
Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs.
Topics: Adolescent; Animals; CD4-Positive T-Lymphocytes; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; DNA-Binding Proteins; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Islets of Langerhans; Lymphocytes; Mice; Mice, Inbred NOD; Mice, Knockout; Propylene Glycols; Sphingosine; T-Lymphocytes; Young Adult | 2010 |
Diabetes prevention by immunomodulatory FTY720 treatment in the LEW.1AR1-iddm rat despite immune cell activation.
Topics: Animals; CD8 Antigens; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Evaluation, Preclinical; Female; Fingolimod Hydrochloride; Gene Expression Regulation; Immune System; Immunomodulation; Immunosuppressive Agents; Lymph Nodes; Lymphocyte Activation; Male; Pancreas; Propylene Glycols; Rats; Sphingosine | 2010 |
Prevention, but not cure, of autoimmune diabetes in a NOD.scid transfer model by FTY720 despite effective modulation of blood T cells.
Topics: Adoptive Transfer; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Fingolimod Hydrochloride; Immunomodulation; Immunosuppressive Agents; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Propylene Glycols; Sphingosine; T-Lymphocytes | 2011 |
Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Type 1; Disease Progression; Fingolimod Hydrochloride; Flow Cytometry; Histocompatibility Antigens Class I; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans; Mice; Mice, Inbred NOD; Mice, Transgenic; Propylene Glycols; Receptors, Antigen, T-Cell; Sphingosine; T-Lymphocytes, Cytotoxic | 2012 |
Effect of FTY720 on some physiological indexes of Non-Obese Diabetic (NOD) Mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fingolimod Hydrochloride; Glutamate Decarboxylase; Immunosuppressive Agents; Kidney; Liver; Mice; Mice, Inbred NOD; Propylene Glycols; Sphingosine; Spleen | 2012 |
Prevention of autoimmune diabetes by FTY720 in nonobese diabetic mice.
Topics: Animals; Body Weight; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Fingolimod Hydrochloride; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Propylene Glycols; Sphingosine | 2002 |
The immune modulator FYT720 prevents autoimmune diabetes in nonobese diabetic mice.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Fingolimod Hydrochloride; Glucose; Immunohistochemistry; Immunosuppressive Agents; Insulin; Islets of Langerhans; Lymphocyte Count; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Propylene Glycols; Random Allocation; Sphingosine | 2003 |
The effect of immunomodulators on prevention of autoimmune diabetes is stage dependent: FTY720 prevents diabetes at three different stages in the diabetes-resistant biobreeding rat.
Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Fingolimod Hydrochloride; Immunity, Innate; Immunosuppressive Agents; Propylene Glycols; Rats; Rats, Inbred BB; Sphingosine; Survival Analysis | 2004 |
Prevention and cure of autoimmune diabetes in nonobese diabetic mice by continuous administration of FTY720.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Mice; Mice, Inbred NOD; Propylene Glycols; Sphingosine | 2005 |
Prevention of experimentally induced autoimmune type I diabetes in rats by the new immunosuppressive reagent FTY720.
Topics: Animals; Diabetes Mellitus, Type 1; Fingolimod Hydrochloride; Immunosuppressive Agents; Islets of Langerhans; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Sphingosine; Thymectomy | 1998 |
Immunosuppressive effect of FTY 720 on autoimmune diabetes models.
Topics: Animals; Diabetes Mellitus, Type 1; Fingolimod Hydrochloride; Immunosuppressive Agents; Inflammation; Islets of Langerhans; Lymphopenia; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Sphingosine; Thymectomy | 1998 |