fingolimod hydrochloride has been researched along with Breast Cancer in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, S; Hait, NC; Ichikawa, H; Ikarashi, M; Koyama, Y; Ling, Y; Moro, K; Nagahashi, M; Okuda, S; Sakata, J; Sato, N; Shimada, Y; Takabe, K; Takeuchi, S; Toshikawa, C; Tsuchida, J; Wakai, T | 1 |
| Cheung, CHA; Chiang, CW; Chung, WP; Huang, WL; Hung, CH; Liao, WA; Su, WC | 1 |
| Singh, SK; Spiegel, S | 1 |
| Hirata, N; Kanda, Y; Ono, A; Yamada, S; Yanagida, S | 1 |
| Chen, Z; Doyle, TM; Grenald, SA; Largent-Milnes, TM; Salvemini, D; Slosky, LM; Spiegel, S; Vanderah, TW; Zhang, H | 1 |
| Alshaker, H; Chao, Y; Cooper, C; Pchejetski, D; Srivats, S; Wang, Q | 1 |
| Cristóbal, I; García-Foncillas, J; Madoz-Gurpide, J; Martínez-Useros, J; Rojo, F; Torrejón, B | 1 |
| Hait, NC; Katsuta, E; Lyon, DE; Nagahashi, M; Rashid, OM; Raza, A; Sturgill, JL; Takabe, K; Yan, L | 1 |
| Abe, M; Allegood, JC; Aoyagi, T; Hait, NC; Huang, WC; Katsuta, E; Milstien, S; Nagahashi, M; Nakajima, M; Sakimura, K; Spiegel, S; Takabe, K; Terracina, KP; Tsuchida, J; Wakai, T; Yamada, A; Yuza, K | 1 |
| Bittman, R; Ohotski, J; Pyne, NJ; Pyne, S; Rosen, H | 1 |
| Agosti, V; Altomare, E; Amodio, N; Barone, A; Bianco, C; Bianco, R; Caraglia, M; Lombardi, A; Marvaso, G; Raimondi, L; Scotti, V; Tagliaferri, P; Tassone, P | 1 |
| Adams, BJ; Allegood, JC; Aoyagi, T; Huang, WC; Milstien, S; Miyazaki, H; Nagahashi, M; Rashid, OM; Spiegel, S; Takabe, K; Terracina, KP; Tsuchida, J; Wakai, T; Yamada, A | 1 |
| Fujita, T; Nagaoka, Y; Otsuki, K; Uesato, S | 1 |
| Bittman, R; Lim, KG; Long, J; Loveridge, C; Pitson, SM; Pyne, NJ; Pyne, S; Tigyi, G; Tonelli, F | 1 |
| Edwards, J; Fujiwara, Y; Long, JS; Pyne, NJ; Pyne, S; Tannahill, CL; Tigyi, G | 1 |
| Bittman, R; Li, Z; Lim, KG; Lu, X; Pyne, NJ; Pyne, S; Tonelli, F | 1 |
| Allen, JD; Alling, N; Haass, NK; Jackson, EA; Martinello-Wilks, R; McGowan, EM; Yagoub, D | 1 |
2 review(s) available for fingolimod hydrochloride and Breast Cancer
| Article | Year |
|---|---|
Sphingosine-1-phosphate signaling: A novel target for simultaneous adjuvant treatment of triple negative breast cancer and chemotherapy-induced neuropathic pain.
Topics: Bortezomib; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Neuralgia; Signal Transduction; Sphingosine; Triple Negative Breast Neoplasms | 2020 |
PP2A regulates signaling through hormonal receptors in breast cancer with important therapeutic implications.
Topics: Breast Neoplasms; Female; Fingolimod Hydrochloride; Humans; Protein Phosphatase 2; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Tumor Suppressor Proteins | 2017 |
16 other study(ies) available for fingolimod hydrochloride and Breast Cancer
| Article | Year |
|---|---|
Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Fingolimod Hydrochloride; Gene Expression; Humans; Lymphatic Metastasis; Lysophospholipids; MCF-7 Cells; Middle Aged; Plasma; Receptors, Estrogen; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors | 2021 |
FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Fingolimod Hydrochloride; Humans; Mice; Mice, Inbred BALB C; Receptor, ErbB-2; Trastuzumab; Xenograft Model Antitumor Assays | 2022 |
FTY720 Inhibits Expansion of Breast Cancer Stem Cells via PP2A Activation.
Topics: Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; MCF-7 Cells; Neoplastic Stem Cells; Phosphotransferases (Alcohol Group Acceptor); Protein Phosphatase 2; Up-Regulation | 2021 |
Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation.
Topics: Animals; Breast Neoplasms; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; Female; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Immunosuppressive Agents; Interleukin-10; Mice; Mice, Inbred C57BL; Neurogenic Inflammation; Proprotein Convertases; Receptors, Lysosphingolipid; Serine Endopeptidases; Signal Transduction; Sphingosine-1-Phosphate Receptors; Spinal Cord; Sulfones; Triazoles | 2017 |
New FTY720-docetaxel nanoparticle therapy overcomes FTY720-induced lymphopenia and inhibits metastatic breast tumour growth.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Female; Fingolimod Hydrochloride; Humans; Lymphopenia; Mice; Nanoparticles; Neoplasm Metastasis; Neoplasm Staging; Taxoids; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Lysophospholipids; Mammary Neoplasms, Experimental; Mice; Obesity; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Retrospective Studies; Sphingosine; STAT3 Transcription Factor | 2017 |
Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Culture Media, Conditioned; Cytokines; Diet, High-Fat; Disease Models, Animal; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Interleukin-6; Lung; Lysophospholipids; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Obesity; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors | 2018 |
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CSK Tyrosine-Protein Kinase; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Estrogen; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Thiazoles; Tyrosine | 2014 |
Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro.
Topics: Apoptosis; Breast Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Fingolimod Hydrochloride; Humans; Propylene Glycols; Radiation Tolerance; Radiation-Sensitizing Agents; Resting Phase, Cell Cycle; Sphingosine | 2014 |
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.
Topics: Activation, Metabolic; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Extracellular Fluid; Female; Fingolimod Hydrochloride; Humans; Isoenzymes; Lysophospholipids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Random Allocation; Sphingosine; Tumor Microenvironment | 2016 |
Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Enzyme Inhibitors; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Indicators and Reagents; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Spectrophotometry, Infrared; Sphingosine | 2008 |
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells.
Topics: Androgens; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fingolimod Hydrochloride; Humans; Male; Muscle, Smooth, Vascular; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Pulmonary Artery; Sphingosine; Stereoisomerism; Vinyl Compounds | 2010 |
News & views in ... Immunotherapy.
Topics: Animals; Antibodies, Blocking; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Fingolimod Hydrochloride; HIV Envelope Protein gp120; HIV Infections; Humans; Maximum Tolerated Dose; Multiple Sclerosis; Ovarian Neoplasms; Propylene Glycols; Sphingosine; Thymidylate Synthase; Virus Internalization | 2009 |
Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Female; Fingolimod Hydrochloride; HEK293 Cells; Humans; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Propylene Glycols; Pyrazoles; Pyridines; Receptor, ErbB-2; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sphingosine | 2010 |
FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells.
Topics: Actins; Allosteric Regulation; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Enzyme Inhibitors; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Lysophospholipids; Models, Chemical; Neoplasm Proteins; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Proteasome Endopeptidase Complex; Sphingosine | 2011 |
Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorimetry; Culture Media, Serum-Free; Deoxyuridine; DNA; Drug Design; Estradiol; Estrogens; Fingolimod Hydrochloride; Fluorescent Dyes; Fulvestrant; Humans; Isopropyl Thiogalactoside; Membrane Potential, Mitochondrial; Mitochondria; Propylene Glycols; Reproducibility of Results; Sphingosine; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p14ARF | 2011 |