Page last updated: 2024-09-02

fingolimod hydrochloride and Brain Injuries

fingolimod hydrochloride has been researched along with Brain Injuries in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Houkin, K; Kawabori, M; Wang, Z1
Wang, H; Zhang, L1
Asci, H; Ozmen, O; Savran, M; Sezik, M; Yalcin, SE; Yavuz, A1
Asci, H; Ozmen, O; Sezik, M; Yavuz, A1
Chen, Y; Dong, S; Tan, X; Yan, B; Yang, Z; Zhang, L; Zheng, Q; Zou, J1
Huang, JJ; Ji, J; Sun, XL; Wang, J; Wang, XP; Xue, TF; Yang, J1
Lovera, J; Villemarette-Pittman, N1
Fichman-Horn, S; Hellmann, MA; Inbar, E; Lev, N; Lotan, I; Luckman, J; Mosberg-Galili, R; Steiner, I; Yakimov, M1
Albert-Weissenberger, C; Hennig, N; Hopp, S; Kleinschnitz, C; Mencl, S; Schuhmann, MK; Sirén, AL1
Ding, K; Wang, H; Wu, Y; Xu, J; Zhang, L1
Fauser, U; Schluesener, HJ; Zhang, Z1

Reviews

2 review(s) available for fingolimod hydrochloride and Brain Injuries

ArticleYear
FTY720 (Fingolimod) Ameliorates Brain Injury through Multiple Mechanisms and is a Strong Candidate for Stroke Treatment.
    Current medicinal chemistry, 2020, Volume: 27, Issue:18

    Topics: Animals; Brain Injuries; Endothelial Cells; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Neural Stem Cells; Propylene Glycols; Receptors, Lysosphingolipid; Stroke

2020
FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential.
    Brain research bulletin, 2020, Volume: 164

    Topics: Animals; Apoptosis; Autophagy; Brain Injuries; Fingolimod Hydrochloride; Neuroprotective Agents; Oxidative Stress; Spinal Cord Injuries

2020

Other Studies

9 other study(ies) available for fingolimod hydrochloride and Brain Injuries

ArticleYear
Combined Use of Magnesium Sulfate and Fingolimod for Antenatal Neuroprotection against Inflammation-Mediated Experimental Preterm Brain Injury in a Rat Model.
    Fetal and pediatric pathology, 2022, Volume: 41, Issue:4

    Topics: Animals; Brain Injuries; Endotoxins; Female; Fingolimod Hydrochloride; Humans; Inflammation; Interleukin-10; Interleukin-6; Magnesium Sulfate; Neuroprotection; Neuroprotective Agents; Pregnancy; Rats

2022
Fingolimod against endotoxin-induced fetal brain injury in a rat model.
    The journal of obstetrics and gynaecology research, 2017, Volume: 43, Issue:11

    Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Disease Models, Animal; Endotoxins; Female; Fetal Diseases; Fingolimod Hydrochloride; Inflammation; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar

2017
FTY720 attenuates iron deposition and glial responses in improving delayed lesion and long-term outcomes of collagenase-induced intracerebral hemorrhage.
    Brain research, 2019, 09-01, Volume: 1718

    Topics: Animals; Brain; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Fingolimod Hydrochloride; Gliosis; Inflammation; Iron; Male; Mice; Mice, Inbred ICR; Neuroglia; Neuroprotective Agents

2019
The Intra-nuclear SphK2-S1P Axis Facilitates M1-to-M2 Shift of Microglia via Suppressing HDAC1-Mediated KLF4 Deacetylation.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Acetylation; Animals; Brain Injuries; Cell Plasticity; Cells, Cultured; Fingolimod Hydrochloride; Glucose; Histone Deacetylase 1; Inflammation Mediators; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lysophospholipids; Microglia; Oxidation-Reduction; Oxygen; Phagocytosis; Phenotype; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Rats; RNA, Small Interfering; Signal Transduction; Sphingosine

2019
Tumefactive multiple sclerosis and fingolimod.
    Journal of the neurological sciences, 2014, Sep-15, Volume: 344, Issue:1-2

    Topics: Brain Injuries; Encephalitis; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Occipital Lobe; Propylene Glycols; Sphingosine

2014
Tumefactive demyelination and a malignant course in an MS patient during and following fingolimod therapy.
    Journal of the neurological sciences, 2014, Sep-15, Volume: 344, Issue:1-2

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain Injuries; Encephalitis; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Magnetic Resonance Imaging; Multiple Sclerosis; Occipital Lobe; Propylene Glycols; Sphingosine

2014
FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation.
    Journal of neuroimmunology, 2014, Sep-15, Volume: 274, Issue:1-2

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Encephalitis; Fingolimod Hydrochloride; Flow Cytometry; Immunosuppressive Agents; Lymphopenia; Mice; Mice, Inbred C57BL; Propylene Glycols; Signal Transduction; Sphingosine; T-Lymphocytes; Treatment Outcome

2014
Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Brain Injuries; Fingolimod Hydrochloride; In Situ Nick-End Labeling; Male; Mice, Inbred ICR; Neurons; Neuroprotection; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction

2016
Early attenuation of lesional interleukin-16 up-regulation by dexamethasone and FTY720 in experimental traumatic brain injury.
    Neuropathology and applied neurobiology, 2008, Volume: 34, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Dexamethasone; Fingolimod Hydrochloride; Functional Laterality; Immunohistochemistry; Interleukin-16; Macrophages; Propylene Glycols; Rats; Sphingosine; Up-Regulation

2008