fingolimod hydrochloride and Body Weight

Topics: Actins; Acute Lung Injury; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Disease Models, Animal; Fingolimod Hydrochloride; Interleukin-1beta; Interleukin-6; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Paraquat; Propylene Glycols; Pulmonary Edema; Pulmonary Fibrosis; Sphingosine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

Topics: Amyotrophic Lateral Sclerosis; Animals; Body Weight; Brain; Cytokines; Disease Models, Animal; Fingolimod Hydrochloride; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mice, Transgenic; Movement Disorders; Mutation; Nitric Oxide Synthase Type II; Spinal Cord; Superoxide Dismutase

Topics: Animals; Body Weight; Endothelial Cells; Fingolimod Hydrochloride; Gene Expression Regulation; Hemodynamics; Humans; Lysophospholipids; Male; Mesenteric Arteries; Muscle Development; Myocytes, Smooth Muscle; Pressure; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Time Factors; Vasoconstriction

Topics: Administration, Oral; Albuminuria; Animals; Blood Pressure; Body Weight; Chemokine CCL2; Chemokine CCL5; Chemokines; Creatinine; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Fingolimod Hydrochloride; Gene Expression Regulation; Immunosuppressive Agents; Inflammation Mediators; Kidney; Kidney Failure, Chronic; Lymphocytes; Macrophages; Male; Nephrectomy; Nephritis; Phenotype; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, CCR1; Receptors, CCR2; Receptors, CCR5; Sphingosine; Time Factors; Transforming Growth Factor beta1

Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; Body Weight; CD11b Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Fingolimod Hydrochloride; Genes, MHC Class II; Indans; Interleukin-2; Interleukin-6; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Oxadiazoles; Proprotein Convertases; Propylene Glycols; Receptors, LDL; Receptors, Lysosphingolipid; Serine Endopeptidases; Sphingosine; Spleen

Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fingolimod Hydrochloride; Glutamate Decarboxylase; Immunosuppressive Agents; Kidney; Liver; Mice; Mice, Inbred NOD; Propylene Glycols; Sphingosine; Spleen

Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Survival; Diabetes Mellitus, Type 2; Female; Fingolimod Hydrochloride; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mice; Propylene Glycols; Sphingosine

Topics: Animals; Body Weight; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Fingolimod Hydrochloride; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Propylene Glycols; Sphingosine

Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Extracellular Matrix; Fibrosis; Fingolimod Hydrochloride; Glomerulosclerosis, Focal Segmental; Heart Rate; Immunosuppressive Agents; Isoantibodies; Lymphocyte Count; Lymphocytes; Male; Propylene Glycols; Proteinuria; Rats; Rats, Wistar; Sphingosine

Topics: Animals; Body Weight; Fingolimod Hydrochloride; Hydroxyproline; Immunosuppressive Agents; Interferon-gamma; Male; Organ Size; Pancreas; Pancreatitis, Chronic; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; RNA, Messenger; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1

Topics: Androgens; Animals; Apoptosis; beta Catenin; Body Weight; Cadherins; Caspase 3; Caspases; Cell Division; Fingolimod Hydrochloride; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Orchiectomy; Platelet Endothelial Cell Adhesion Molecule-1; Propylene Glycols; Prostate-Specific Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Vascular Endothelial Growth Factor A

Topics: Acute Disease; Animals; Body Weight; Cytokines; Fingolimod Hydrochloride; Graft vs Host Disease; Immunosuppressive Agents; Intestine, Small; Liver; Lymphocyte Count; Male; Propylene Glycols; Rats; Rats, Inbred WF; Skin; Sphingosine; T-Lymphocyte Subsets; Transplantation Chimera

Topics: Animals; Body Weight; Cell Count; Creatinine; Cyclosporine; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Histocompatibility Antigens Class II; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Kidney; Lymph Nodes; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Potassium; Propylene Glycols; Skin Transplantation; Sodium; Sphingosine; Spleen; Transplantation, Homologous

Topics: Animals; Antibodies, Blocking; Blood Pressure; Body Weight; Collagen Type III; Extracellular Matrix; Fibronectins; Fingolimod Hydrochloride; Glomerulonephritis, Membranoproliferative; Heart Rate; Immunohistochemistry; Kidney Glomerulus; Leukocyte Count; Lipopolysaccharides; Male; Nitric Oxide Synthase Type II; Plasminogen Activator Inhibitor 1; Propylene Glycols; Proteinuria; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Thy-1 Antigens; Transforming Growth Factor beta

Topics: Analysis of Variance; Animals; Body Weight; Disease Models, Animal; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Longitudinal Studies; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neural Conduction; Propylene Glycols; Rats; Reaction Time; Sphingosine; Spinal Cord; Time Factors

Topics: Animals; Body Weight; CD3 Complex; Disease Models, Animal; Ectodysplasins; Fingolimod Hydrochloride; Flow Cytometry; Immunosuppressive Agents; Lymphocytes; Macrophages; Male; Neuritis, Autoimmune, Experimental; Propylene Glycols; Rats; Rats, Inbred Lew; Sciatic Nerve; Sphingosine; Sulfonamides

Topics: Animals; Body Weight; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Liver; Organ Size; Propylene Glycols; Rats; Sphingosine; Spleen; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin

Topics: Animals; Antibodies; Arrestin; Autoimmune Diseases; Blood Cell Count; Body Weight; Chi-Square Distribution; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Retinitis; Sphingosine; Statistics, Nonparametric; T-Lymphocytes; Uveitis

Topics: Analysis of Variance; Animals; Autoimmune Diseases; Body Weight; Fingolimod Hydrochloride; Immunosuppressive Agents; Injections, Intraperitoneal; Lymphocyte Count; Lymphocytes; Male; Myocarditis; Organ Size; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Tacrolimus

Topics: Animals; Body Weight; Drug Therapy, Combination; Everolimus; Fingolimod Hydrochloride; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Lymphocyte Count; Male; Myocardium; Propylene Glycols; Rats; Rats, Inbred Lew; Sirolimus; Sphingosine; Transplantation, Heterotopic

Topics: Adjuvants, Immunologic; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Heart Transplantation; Histocompatibility Antigens; Immunosuppressive Agents; Lymphocyte Count; Male; Models, Animal; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Skin Transplantation; Sphingosine