Page last updated: 2024-09-02

fingolimod hydrochloride and Atrophy

fingolimod hydrochloride has been researched along with Atrophy in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (11.11)	29.6817
2010's	12 (66.67)	24.3611
2020's	4 (22.22)	2.80

Authors

Authors	Studies
Dahlke, F; Häring, DA; Kappos, L; Kropshofer, H; Kuhle, J; Leppert, D; Meinert, R; Patil, A; Tomic, D	1
Filippi, M; Moiola, L; Pagani, E; Preziosa, P; Rocca, MA; Rodegher, M; Storelli, L	1
Eshaghi, A	1
Aoki, R; Hirano, S; Kuwabara, S; Masuda, H; Mori, M; Ohtani, R; Uchida, T; Uzawa, A	1
Bakshi, R; Chitnis, T; Chu, R; Dupuy, SL; Healy, BC; Khalid, F; Kim, G; Tauhid, S; Tummala, S; Weiner, HL; Yousuf, F	1
Beckmann, N; Doelemeyer, A; Dubost, V; Jivkov, M; Schmid, C; Smith, PA; Theil, D; Zurbruegg, S	1
Ciccarelli, O; Schoonheim, MM	1
Gaetano, L; Häring, DA; Kappos, L; Mueller-Lenke, N; Radue, EW; Sprenger, T; Thakur, A; Tomic, D	1
Bajrami, A; Calabrese, M; Castellaro, M; Monaco, S; Montemezzi, S; Pitteri, M; Pizzini, F; Romualdi, C	1
De Stefano, N; Giovannoni, G; Haering, DA; Kappos, L; Langdon, D; Piani-Meier, D; Sormani, MP; Tomic, D	1
Hirano, S; Kojima, K; Kuwabara, S; Masuda, H; Mori, M; Ohtani, R; Uchida, T; Uzawa, A	1
Baumann, JM; Bhaumik, SK; Chougnet, CA; Dunn, RS; Kallapur, SG; Kuan, CY; Lee, YH; Lewkowich, IP; Li, Y; Lin, SH; Lin, X; Lindquist, DM; Liu, CY; Murali-Krishna, K; Shie, FS; Sun, YY; Wills-Karp, M; Yang, D; Zhang, Y	1
Bankó, N; Bencsik, K; Csete, G; Faragó, P; Kincses, ZT; Király, A; Szabó, N; Tóth, E; Vécsei, L; Veréb, D	1
Cree, BA; De Stefano, N; Freedman, MS; Häring, DA; Kappos, L; Piani Meier, D; Radue, EW; Smith, T; Sormani, MP; Sprenger, T; Tomic, D	1
Deller, T; Ferreirós, N; Maggio, N; Scholich, K; Vlachos, A; Willems, LM; Zahn, N	1
García-Merino, JA; Sánchez, AJ	1
Isoyama, N; Kishi, Y; Matsumura, M; Naito, K; Takahara, S; Takai, K; Tsuchida, M; Uchiyama, K	1
Isoyama, N; Matsumura, M; Naito, K; Takai, K; Tsuchida, M	1

Reviews

1 review(s) available for fingolimod hydrochloride and Atrophy

Article	Year
Grey matter atrophy in patients suffering from multiple sclerosis. Ideggyogyaszati szemle, 2014, Sep-30, Volume: 67, Issue:9-10 Topics: Adjuvants, Immunologic; Antibodies, Monoclonal, Humanized; Atrophy; Fingolimod Hydrochloride; Glatiramer Acetate; Gray Matter; Humans; Immunosuppressive Agents; Interferon beta-1a; Interferon beta-1b; Interferon-beta; Multiple Sclerosis; Muscle, Skeletal; Natalizumab; Peptides; Predictive Value of Tests; Propylene Glycols; Sphingosine; Treatment Outcome	2014

Article

Year

Grey matter atrophy in patients suffering from multiple sclerosis.

Ideggyogyaszati szemle, 2014, Sep-30, Volume: 67, Issue:9-10

Topics: Adjuvants, Immunologic; Antibodies, Monoclonal, Humanized; Atrophy; Fingolimod Hydrochloride; Glatiramer Acetate; Gray Matter; Humans; Immunosuppressive Agents; Interferon beta-1a; Interferon beta-1b; Interferon-beta; Multiple Sclerosis; Muscle, Skeletal; Natalizumab; Peptides; Predictive Value of Tests; Propylene Glycols; Sphingosine; Treatment Outcome

2014

Trials

3 trial(s) available for fingolimod hydrochloride and Atrophy

Article	Year
Two-year regional grey and white matter volume changes with natalizumab and fingolimod. Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:5 Topics: Adult; Atrophy; Brain; Disease Progression; Female; Fingolimod Hydrochloride; Gray Matter; Humans; Immunologic Factors; Longitudinal Studies; Magnetic Resonance Imaging; Male; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Neuroimaging; Prospective Studies; White Matter	2020
Fingolimod effect on gray matter, thalamus, and white matter in patients with multiple sclerosis. Neurology, 2018, 04-10, Volume: 90, Issue:15 Topics: Aged; Atrophy; Disease Progression; Double-Blind Method; Female; Fingolimod Hydrochloride; Gray Matter; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Multiple Sclerosis, Relapsing-Remitting; Organ Size; Thalamus; Treatment Outcome; White Matter	2018
The effect of fingolimod on focal and diffuse grey matter damage in active MS patients. Journal of neurology, 2018, Volume: 265, Issue:9 Topics: Adolescent; Adult; Atrophy; Disease Progression; Female; Fingolimod Hydrochloride; Gray Matter; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Outcome Assessment, Health Care; Single-Blind Method; Young Adult	2018

Other Studies

14 other study(ies) available for fingolimod hydrochloride and Atrophy

Article	Year
Blood Neurofilament Light in Progressive Multiple Sclerosis: Post Hoc Analysis of 2 Randomized Controlled Trials. Neurology, 2022, 05-24, Volume: 98, Issue:21 Topics: Acute Disease; Atrophy; Biomarkers; Disease Progression; Fingolimod Hydrochloride; Humans; Intermediate Filaments; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Randomized Controlled Trials as Topic	2022
First approved treatment in children with multiple sclerosis slows brain atrophy. Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:5 Topics: Atrophy; Brain; Child; Fingolimod Hydrochloride; Humans; Magnetic Resonance Imaging; Multiple Sclerosis	2020
Comparison of brain atrophy in patients with multiple sclerosis treated with first- versus second-generation disease modifying therapy without clinical relapse. European journal of neurology, 2020, Volume: 27, Issue:10 Topics: Atrophy; Brain; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunosuppressive Agents; Interferon-beta; Multiple Sclerosis, Relapsing-Remitting; Recurrence	2020
A two-year study using cerebral gray matter volume to assess the response to fingolimod therapy in multiple sclerosis. Journal of the neurological sciences, 2017, Dec-15, Volume: 383 Topics: Adult; Atrophy; Brain; Disability Evaluation; Female; Fingolimod Hydrochloride; Gray Matter; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Organ Size; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult	2017
Fingolimod inhibits brain atrophy and promotes brain-derived neurotrophic factor in an animal model of multiple sclerosis. Journal of neuroimmunology, 2018, 05-15, Volume: 318 Topics: Animals; Atrophy; Brain; Brain-Derived Neurotrophic Factor; Crotonates; Encephalomyelitis, Autoimmune, Experimental; Female; Fingolimod Hydrochloride; Hydroxybutyrates; Immunosuppressive Agents; Interleukin-17; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Nitriles; Toluidines	2018
The value of including thalamic atrophy as a clinical trial endpoint in multiple sclerosis. Neurology, 2018, 04-10, Volume: 90, Issue:15 Topics: Atrophy; Fingolimod Hydrochloride; Gray Matter; Humans; Multiple Sclerosis; Thalamus; White Matter	2018
Learning ability correlates with brain atrophy and disability progression in RRMS. Journal of neurology, neurosurgery, and psychiatry, 2019, Volume: 90, Issue:1 Topics: Adult; Aptitude; Atrophy; Brain; Disease Progression; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Learning; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Randomized Controlled Trials as Topic	2019
Relapse numbers and earlier intervention by disease modifying drugs are related with progression of less brain atrophy in patients with multiple sclerosis. Journal of the neurological sciences, 2019, Aug-15, Volume: 403 Topics: Adolescent; Adult; Aged; Atrophy; Brain; Disease Progression; Early Medical Intervention; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Recurrence; Retrospective Studies; Young Adult	2019
Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Dec-03, Volume: 34, Issue:49 Topics: Animals; Animals, Newborn; Atrophy; Blood-Brain Barrier; Brain; Cell Movement; Chorioamnionitis; Cytokines; Dose-Response Relationship, Drug; Female; Fingolimod Hydrochloride; Humans; Hypoxia-Ischemia, Brain; Immunosuppressive Agents; Infant, Newborn; Inflammation; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; NF-kappa B; Pregnancy; Propylene Glycols; Rats; Receptors, Interleukin; Sphingosine; T-Lymphocytes; White Matter	2014
Inclusion of brain volume loss in a revised measure of 'no evidence of disease activity' (NEDA-4) in relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:10 Topics: Adolescent; Adult; Atrophy; Brain; Clinical Trials, Phase III as Topic; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Organ Size; Treatment Outcome; Young Adult	2016
Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophy. Acta neuropathologica communications, 2016, Mar-31, Volume: 4 Topics: Animals; Animals, Newborn; Atrophy; Calcium-Binding Proteins; Dendrites; Denervation; Entorhinal Cortex; Fingolimod Hydrochloride; Gene Expression Regulation; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Organ Culture Techniques; Perforant Pathway; Phosphoserine; Receptors, Lysosphingolipid; Time Factors; Up-Regulation	2016
[Basic mechanisms of action of fingolimod in relation to multiple sclerosis]. Revista de neurologia, 2012, Jul-01, Volume: 55, Issue:1 Topics: Animals; Atrophy; B-Lymphocytes; Brain; Cell Movement; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; L-Selectin; Lysophospholipids; Mice; Molecular Structure; Multiple Sclerosis; Neuroglia; Propylene Glycols; Rats; Receptors, CCR7; Receptors, Lysosphingolipid; Sphingosine; T-Lymphocyte Subsets; Th17 Cells	2012
Effects of FTY720 on rat lymphoid organs. Transplantation proceedings, 2004, Volume: 36, Issue:8 Topics: Animals; Antigens, CD; Atrophy; Fingolimod Hydrochloride; Immunosuppressive Agents; Lymphocytes; Lymphoid Tissue; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Spleen; Thymus Gland	2004
Evidence that FTY720 induces rat thymocyte apoptosis. Transplant immunology, 2006, Volume: 15, Issue:4 Topics: Animals; Apoptosis; Atrophy; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; DNA Fragmentation; Fingolimod Hydrochloride; Flow Cytometry; Immunosuppressive Agents; In Situ Nick-End Labeling; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Sphingosine; T-Lymphocyte Subsets; Thymus Gland	2006