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fingolimod hydrochloride and Astrocytoma, Grade IV

fingolimod hydrochloride has been researched along with Astrocytoma, Grade IV in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Doello, K; Mesas, C; Ortiz, R; Perazzoli, G; Quiñonero, F; Rama, AR; Vélez, C1
Liu, L; Ma, M; Wu, H; Zhang, Y1
Cambron, B; Delrée, P; Gustin, T; Jacobs, S; London, F1
Cheng, H; Guo, RB; Guo, XD; Ji, J; Sun, XL; Sun, YQ; Xue, TF1
Al Barim, B; Di Fazio, P; Kolodziej, MA; Nagl, J; Schwarm, FP; Stein, M; Uhl, E; Uhle, F; Weigand, MA1
Wang, H; Zhang, L1
Alessandri, G; Bornati, A; Campanella, R; de Rezende, G; Di Vito, C; Giussani, P; Hadi, LA; Marfia, G; Navone, SE; Parati, E; Rampini, P; Riboni, L; Riccitelli, E; Tringali, C; Viani, P1
Ding, K; Wang, H; Xu, J; Zhang, L; Zhu, J1
Ding, K; Wang, H; Xu, J; Zhang, L1
Golzy, N; Pouratian, N; Sharim, J; Tashjian, R1
Estrada-Bernal, A; Palanichamy, K; Ray Chaudhury, A; Van Brocklyn, JR1

Other Studies

11 other study(ies) available for fingolimod hydrochloride and Astrocytoma, Grade IV

ArticleYear
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
    Neurotoxicity research, 2022, Volume: 40, Issue:6

    Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydrochloride; Glioblastoma; Haloperidol; Humans; Levetiracetam; Methotrimeprazine; Valproic Acid

2022
Modulation of blood-brain tumor barrier for delivery of magnetic hyperthermia to brain cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Blood-Brain Barrier; Brain Neoplasms; Endothelial Cells; Fingolimod Hydrochloride; Glioblastoma; Humans; Hyperthermia, Induced; Magnetic Phenomena

2023
Glioblastoma in a fingolimod-treated multiple sclerosis patient: Causal or coincidental association?
    Multiple sclerosis and related disorders, 2020, Volume: 41

    Topics: Brain; Brain Neoplasms; Female; Fingolimod Hydrochloride; Glioblastoma; Humans; Middle Aged; Multiple Sclerosis; Sphingosine 1 Phosphate Receptor Modulators

2020
FTY720 Exerts Anti-Glioma Effects by Regulating the Glioma Microenvironment Through Increased CXCR4 Internalization by Glioma-Associated Microglia.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Allografts; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Polarity; Disease Models, Animal; Fingolimod Hydrochloride; Glioblastoma; Macrophages; Male; Microglia; Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, CXCR4; Signal Transduction; Tumor Microenvironment

2020
Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
    International journal of oncology, 2020, Volume: 57, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Fingolimod Hydrochloride; Glioblastoma; Humans; rho-Associated Kinases; Signal Transduction; Sphingosine 1 Phosphate Receptor Modulators; Temozolomide

2020
FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomide.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidant Response Elements; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Fingolimod Hydrochloride; Gene Knockdown Techniques; Glioblastoma; Heme Oxygenase-1; Humans; NF-E2-Related Factor 2; RNA, Messenger; RNA, Small Interfering; Temozolomide

2017
Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells.
    Glia, 2014, Volume: 62, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Ceramides; Epidermal Growth Factor; Extracellular Fluid; Fibroblast Growth Factor 2; Fingolimod Hydrochloride; Glioblastoma; Humans; Immunosuppressive Agents; Ki-67 Antigen; Lysophospholipids; Mice; Mice, SCID; Middle Aged; Neoplastic Stem Cells; Propylene Glycols; Sphingolipids; Sphingosine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:11

    Topics: Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Fingolimod Hydrochloride; Glioblastoma; Humans; Immunosuppressive Agents; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propylene Glycols; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sphingosine; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Wound Healing

2014
FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
    Toxicology letters, 2015, Jul-02, Volume: 236, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Biomarkers; Cell Line, Tumor; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Glioblastoma; Humans; Male; Membrane Proteins; Mice, Nude; Necrosis; Neoplasm Proteins; Propylene Glycols; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; Signal Transduction; Sphingosine; Tumor Burden; Xenograft Model Antitumor Assays

2015
Glioblastoma following treatment with fingolimod for relapsing-remitting multiple sclerosis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 30

    Topics: Brain Neoplasms; Female; Fingolimod Hydrochloride; Glioblastoma; Humans; Immunosuppressive Agents; Middle Aged; Multiple Sclerosis, Relapsing-Remitting

2016
Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Brain Neoplasms; Dacarbazine; Extracellular Signal-Regulated MAP Kinases; Fingolimod Hydrochloride; Glioblastoma; Humans; Induction Chemotherapy; Membrane Proteins; Mice; Mice, Nude; Neoplastic Stem Cells; Propylene Glycols; Proto-Oncogene Proteins; Receptors, Lysosphingolipid; Sphingosine; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2012