Page last updated: 2024-09-02

fingolimod hydrochloride and Asthma

fingolimod hydrochloride has been researched along with Asthma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's6 (50.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Croft, M; Gracias, D; Sethi, GS1
El-Sheakh, AR; Makled, MN1
Daniels, JM; Killestein, J; Looysen, EE; van Rossum, JA1
Allegood, JC; Avni, D; Conrad, DH; Hait, NC; Huang, WC; Maceyka, M; Milstien, S; Montpetit, A; Newton, J; Oyeniran, C; Spiegel, S; Sturgill, JL1
Brewer, JM; Bundick, RV; Choo-Kang, BS; Garside, P; Gibson, VB; Hutchison, S; Leishman, AJ; McInnes, IB1
Hendriks, RW; Hoogsteden, HC; KleinJan, A; Lambrecht, BN; Leman, K; van Nimwegen, M; Willart, M1
Lai, WQ; Leung, BP; Wong, WS1
Hassan, M; Karmouty-Quintana, H; Marti-Solano, M; Martin, JG; Risse, PA; Siddiqui, S; Tsuchiya, K; Xicota-Vila, L1
Fozard, JR; Trifilieff, A1
Brinkmann, V; Kemeny, DM; Manlius, C; Sawicka, E; Trifilieff, A; Walker, C; Zuany-Amorim, C1
Baumruker, T; Brinkmann, V1
Hammad, H; Hijdra, D; Hoogsteden, HC; Idzko, M; Kool, M; Lambrecht, BN; Müller, T; Soullié, T; van Nimwegen, M; Willart, MA1

Reviews

2 review(s) available for fingolimod hydrochloride and Asthma

ArticleYear
Sphingosine kinase and sphingosine 1-phosphate in asthma.
    Bioscience reports, 2011, Volume: 31, Issue:2

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Epithelial Cells; Fingolimod Hydrochloride; Humans; Inflammation; Lung; Lysophospholipids; Mast Cells; Mice; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Lysosphingolipid; Signal Transduction; Sphingolipids; Sphingosine

2011
Pulmonary and vascular pharmacology of sphingosine 1-phosphate.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:3

    Topics: Animals; Asthma; Capillary Permeability; Endothelium, Vascular; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Lung; Lysophospholipids; Mast Cells; Muscle, Smooth, Vascular; Propylene Glycols; Receptors, Lysosphingolipid; Respiratory Mucosa; Signal Transduction; Sphingosine; T-Lymphocytes; Vasoconstriction

2006

Other Studies

10 other study(ies) available for fingolimod hydrochloride and Asthma

ArticleYear
Contribution of circulatory cells to asthma exacerbations and lung tissue-resident CD4 T cell memory.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Allergens; Animals; Asthma; CD4-Positive T-Lymphocytes; Fingolimod Hydrochloride; Immunologic Memory; Lung; Mice; Pneumonia; Recurrence

2022
Fingolimod attenuates ovalbumin-induced airway inflammation via inhibiting MAPK/ERK signaling in mice.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Fingolimod Hydrochloride; Inflammation; Interleukin-13; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Ovalbumin

2023
Fingolimod-induced asthma deterioration in a patient with relapsing-remitting multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2014, Volume: 20, Issue:13

    Topics: Adult; Asthma; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Propylene Glycols; Sphingosine

2014
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.
    The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:4

    Topics: Animals; Asthma; Cell Line, Tumor; Ceramides; Epithelial Cells; Female; Fingolimod Hydrochloride; Gene Expression Regulation; Homeostasis; Humans; Immunosuppressive Agents; Macrophages; Membrane Proteins; Mice; Respiratory Mucosa

2015
An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation.
    Clinical and experimental immunology, 2009, Volume: 155, Issue:1

    Topics: Adoptive Transfer; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Division; Cell Movement; Cytokines; Eosinophilia; Female; Fingolimod Hydrochloride; Flow Cytometry; Humans; Immunosuppressive Agents; Lung; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microscopy, Confocal; Models, Animal; Ovalbumin; Propylene Glycols; Receptors, Antigen, T-Cell; Sphingosine; Th2 Cells; Time Factors

2009
United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, Volume: 40, Issue:3

    Topics: Animals; Asthma; Disease Models, Animal; Female; Fingolimod Hydrochloride; Inflammation; Mice; Mice, Inbred BALB C; Ovalbumin; Propylene Glycols; Rhinitis, Allergic, Perennial; Sphingosine; Th2 Cells

2010
Treatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Apr-15, Volume: 302, Issue:8

    Topics: Airway Remodeling; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; CD3 Complex; Fingolimod Hydrochloride; Immunosuppressive Agents; Lysophospholipids; Male; Muscle, Smooth; Propylene Glycols; Rats; Severity of Illness Index; Sphingosine; Treatment Outcome

2012
Sphingosine-1-phosphate-induced airway hyper-reactivity in rodents is mediated by the sphingosine-1-phosphate type 3 receptor.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:2

    Topics: Albuterol; Animals; Asthma; beta-Alanine; Bronchial Hyperreactivity; Bronchoconstriction; Fingolimod Hydrochloride; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Propylene Glycols; Rats; Rats, Inbred BN; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Tachyphylaxis; Thiophenes; Trachea

2012
Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Dec-01, Volume: 171, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bystander Effect; Cell Movement; Disease Models, Animal; Epitopes, T-Lymphocyte; Fingolimod Hydrochloride; Immunosuppressive Agents; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Propylene Glycols; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingosine; Th1 Cells; Th2 Cells

2003
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:11

    Topics: Administration, Inhalation; Allergens; Animals; Asthma; Cell Differentiation; Cell Movement; Cell Polarity; Dendritic Cells; Disease Models, Animal; Fingolimod Hydrochloride; Gene Expression Regulation; Heart; Lymph Nodes; Lymphocytes; Lysophospholipids; Mice; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine

2006