fingolimod hydrochloride has been researched along with Adjuvant Arthritis in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bu, YH; Chen, FY; Deng, R; Dong, XT; Gan, PR; Ke, JT; Wang, RH; Wu, H | 1 |
| Li, J; Meng, H; Wang, L; Wen, S; Zhang, J; Zhang, Y; Zhao, K; Zhu, C | 1 |
| Banno, R; Fujita, T; Kohno, T; Matsushima, Y; Mikami, N; Miyawaki, M; Otani, F; Takatsuji, M; Tsuji, T; Tsujikawa, K; Yoshida, Y | 1 |
| Gu, D; Han, J; Han, Y; He, J; He, Y; Jie, H; Lao, X; Li, X; Liu, X; Sun, E; Zhou, Q | 1 |
| Brand, DD; Hasty, KA; Miller, DC; Rosloniec, EF; Whittington, KB | 1 |
| Arunachalam, P; Balimane, PV; Banas, DM; Barrish, JC; Carter, PH; Cherney, RJ; Cornelius, G; Cvijic, ME; D'Arienzo, CJ; Dhar, TG; Dyckman, AJ; Gilmore, JL; Guo, WW; Ko, SS; Langevine, CM; Lehman-McKeeman, L; Li, P; Marino, AM; Mathur, A; McIntyre, KW; Ramasamy, D; Salter-Cid, LM; Shen, DR; Sheppeck, JE; Shuster, DJ; Srivastava, AS; Taylor, TL; Warrack, BM; Watterson, SH; Wu, DR; Xiao, HY; Xie, J; Yang, Z; Yarde, M; Zhang, Y | 1 |
| Chung, DH; Hwang, SJ; Kim, HY; Kim, JH; Kim, S | 1 |
| Angyal, A; Egelston, C; Glant, TT; Kobezda, T; László, A; Mikecz, K; Olasz, K | 1 |
| Frey, O; Kamradt, T | 1 |
| Guo, D; He, S; Tan, W; Wang, F | 1 |
| Imayoshi, T; Matsuura, M; Okumoto, T | 1 |
| Chiba, K; Imayoshi, T; Matsuura, M; Okumoto, T | 1 |
12 other study(ies) available for fingolimod hydrochloride and Adjuvant Arthritis
| Article | Year |
|---|---|
Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Fingolimod Hydrochloride; Interferon-gamma; Iridoids; Lipopolysaccharides; Macrophages; Mice; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction | 2022 |
FTY720 Inhibits the Development of Collagen-Induced Arthritis in Mice by Suppressing the Recruitment of CD4
Topics: Animals; Arthritis, Experimental; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Male; Mice; Mice, Inbred DBA; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Synoviocytes; Time Factors; Tumor Necrosis Factor-alpha | 2021 |
Functional Mechanism(s) of the Inhibition of Disease Progression by Combination Treatment with Fingolimod Plus Pathogenic Antigen in a Glucose-6-phosphate Isomerase Peptide-Induced Arthritis Mouse Model.
Topics: Animals; Antigens; Arthritis, Experimental; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Combined Modality Therapy; Disease Models, Animal; Disease Progression; Fingolimod Hydrochloride; Glucose-6-Phosphate Isomerase; Immune Tolerance; Immunosuppressive Agents; Male; Mice, Inbred DBA; Peptides; T-Lymphocytes, Regulatory | 2015 |
FTY720 Abrogates Collagen-Induced Arthritis by Hindering Dendritic Cell Migration to Local Lymph Nodes.
Topics: Animals; Arthritis, Experimental; Cell Movement; Chemokines; Cytokines; Dendritic Cells; Fingolimod Hydrochloride; Immunosuppressive Agents; Lymph Nodes; Male; Mice; Mice, Inbred DBA | 2015 |
The CII-specific autoimmune T-cell response develops in the presence of FTY720 but is regulated by enhanced Treg cells that inhibit the development of autoimmune arthritis.
Topics: Animals; Arthritis, Experimental; Autoimmune Diseases; Autoimmunity; Collagen Type II; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; T-Lymphocytes, Regulatory | 2016 |
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P
Topics: Animals; Arthritis, Experimental; Dogs; Dose-Response Relationship, Drug; Drug Design; Fingolimod Hydrochloride; Freund's Adjuvant; Heterocyclic Compounds, 3-Ring; Ligands; Lymphocytes; Macaca fascicularis; Male; Mice; Molecular Structure; Mycobacterium; Rats; Rats, Inbred Lew; Receptors, Lysosphingolipid; Structure-Activity Relationship; Tissue Distribution | 2016 |
FTY720, a sphingosine 1-phosphate receptor modulator, inhibits CD1d-restricted NKT cells by suppressing cytokine production but not migration.
Topics: Animals; Antibodies; Antigens, CD1d; Arthritis, Experimental; Cell Movement; Cytokines; Fingolimod Hydrochloride; GATA3 Transcription Factor; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, Transgenic; Natural Killer T-Cells; Propylene Glycols; Receptors, Antigen, T-Cell; Receptors, GABA-A; Receptors, Lysosphingolipid; Sphingosine; T-Lymphocytes | 2010 |
Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
Topics: Adoptive Transfer; Animals; Antigen-Presenting Cells; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Cell Movement; Female; Fingolimod Hydrochloride; Gene Knock-In Techniques; Humans; Immunosuppressive Agents; Joints; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Propylene Glycols; Proteoglycans; Sphingosine; T-Lymphocytes | 2010 |
Arthritis: where are the T cells?
Topics: Animals; Antigens; Arthritis; Arthritis, Experimental; Disease Models, Animal; Fingolimod Hydrochloride; Humans; Joints; Lysophospholipids; Mice; Propylene Glycols; Sphingosine; T-Lymphocytes, Helper-Inducer | 2010 |
Reduction of CD4 positive T cells and improvement of pathological changes of collagen-induced arthritis by FTY720.
Topics: Animals; Ankle Joint; Arthritis, Experimental; Bone Density; CD4 Antigens; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Chickens; Collagen Type II; Female; Fingolimod Hydrochloride; Flow Cytometry; Forelimb; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Prednisone; Propylene Glycols; Rats; Rats, Wistar; Sphingosine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Weight Loss | 2007 |
Effect of FTY720, a novel immunosuppressant, on adjuvant- and collagen-induced arthritis in rats.
Topics: Animals; Arthritis, Experimental; Collagen; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Prednisolone; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Ribonucleosides; Sphingosine | 2000 |
Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats.
Topics: Animals; Arthritis, Experimental; Cyclosporine; Edema; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Lymphocytes; Male; Monocytes; Mycobacterium tuberculosis; Neutrophils; Osteolysis; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Tacrolimus | 2000 |