Page last updated: 2024-09-02

fingolimod hydrochloride and Acute Lung Injury

fingolimod hydrochloride has been researched along with Acute Lung Injury in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (66.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Bandela, M; Belvitch, P; Brown, ME; Chen, J; Dudek, SM; Garcia, JGN; Letsiou, E; Meliton, LN; Wang, H; Wang, L1
An, S; Gao, C; Huang, J; Jiang, R; Luo, H; Qian, Y; Song, Y; Zhang, J; Zhao, X1
Chen, CL; Shi, ZA; Tu, FP; Wan, Y; Wu, ZC; Yu, CX1
Kang, DL; Li, TT; Shi, ZA; Su, H; Tu, FP1
Bai, C; Chen, H; Huang, Z; Liu, G; Liu, H; Niu, W; Qin, Y; Wen, G; Zhang, X; Zhao, Y; Zhu, C1
Bai, C; Chen, H; Huang, Z; Liu, G; Liu, H; Niu, W; Qin, Y; Wang, H; Wang, S; Zhang, X1
Abassi, T; Berdyshev, E; Bittman, R; Dudek, SM; Garcia, JG; Huang, LS; Jacobson, JR; Mathew, B; Moreno-Vinasco, L; Natarajan, V; Wang, L; Weichselbaum, R; Zhao, Y1
Bittman, R; Camp, SM; Dudek, SM; Garcia, JG; Letsiou, E; Moreno-Vinasco, L; Sammani, S; Wang, L; Wang, T1
Lv, L; Qian, J; Ye, S; Ye, Y; Zhu, C1
Bonitz, JA; Chandler, B; Deitch, EA; Feketeova, E; Prescott, LM; Qin, Y; Son, JY; Tomaio, JN1
Hla, T; Proia, RL1
Bittman, R; Dudek, SM; Garcia, JG; Wang, L1

Reviews

2 review(s) available for fingolimod hydrochloride and Acute Lung Injury

ArticleYear
Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
    American journal of respiratory cell and molecular biology, 2013, Volume: 49, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Biomarkers; Capillary Permeability; Fingolimod Hydrochloride; Humans; Lung; Lysophospholipids; Membrane Proteins; Nerve Tissue Proteins; Phosphotransferases (Alcohol Group Acceptor); Pneumonia; Propylene Glycols; Receptors, Lysosphingolipid; Sepsis; Sphingosine; Transferases (Other Substituted Phosphate Groups); Translational Research, Biomedical

2013
Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.
    The Journal of clinical investigation, 2015, Volume: 125, Issue:4

    Topics: Acute Lung Injury; Anemia, Sickle Cell; Animals; Autoimmune Diseases; Cardiovascular Diseases; Cell Physiological Phenomena; Disease Models, Animal; Fingolimod Hydrochloride; Hematopoietic Stem Cell Mobilization; Humans; Influenza, Human; Lysophospholipids; Membrane Lipids; Mice; Multiple Sclerosis; Neoplasms; Neovascularization, Physiologic; Neurogenesis; Propylene Glycols; Receptors, Lysosphingolipid; Sphingolipids; Sphingosine

2015

Other Studies

10 other study(ies) available for fingolimod hydrochloride and Acute Lung Injury

ArticleYear
MRSA-induced endothelial permeability and acute lung injury are attenuated by FTY720 S-phosphonate.
    American journal of physiology. Lung cellular and molecular physiology, 2022, 01-01, Volume: 322, Issue:1

    Topics: Acute Lung Injury; Animals; Antigens, CD; Cadherins; Cell Membrane Permeability; Cytoprotection; Cytoskeleton; Endothelial Cells; Enzyme Activation; Fingolimod Hydrochloride; Humans; Inflammation; Methicillin-Resistant Staphylococcus aureus; Mice; Myosin Light Chains; Organophosphonates; Phosphorylation; rhoA GTP-Binding Protein; Signal Transduction

2022
Fingolimod Attenuates Lung Injury and Cardiac Dysfunction after Traumatic Brain Injury.
    Journal of neurotrauma, 2020, 10-01, Volume: 37, Issue:19

    Topics: Acute Lung Injury; Animals; Brain Injuries, Traumatic; Cardiac Output; Cytokines; Disease Models, Animal; Echocardiography; Fingolimod Hydrochloride; Heart Diseases; Lung; Male; Mice; Mice, Inbred C57BL; Myocardium; Sphingosine 1 Phosphate Receptor Modulators

2020
The effect of FTY720 at different doses and time-points on LPS-induced acute lung injury in rats.
    International immunopharmacology, 2021, Volume: 99

    Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Blood-Air Barrier; Cytokines; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Immunosuppressive Agents; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Male; NF-kappa B; Oxygen; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tomography, X-Ray Computed

2021
Fingolimod attenuates renal ischemia/reperfusion-induced acute lung injury by inhibiting inflammation and apoptosis and modulating S1P metabolism.
    The Journal of international medical research, 2021, Volume: 49, Issue:8

    Topics: Acute Lung Injury; Animals; Apoptosis; Fingolimod Hydrochloride; Inflammation; Ischemia; Lysophospholipids; Rats; Reperfusion; Reperfusion Injury; Sphingosine

2021
Transcriptomic analysis of lung tissues after hUC-MSCs and FTY720 treatment of lipopolysaccharide-induced acute lung injury in mouse models.
    International immunopharmacology, 2018, Volume: 63

    Topics: Acute Lung Injury; Animals; Combined Modality Therapy; Female; Fingolimod Hydrochloride; Gene Expression Profiling; Immunosuppressive Agents; Lipopolysaccharides; Lung; Mesenchymal Stem Cell Transplantation; Mice, Inbred C57BL; Respiratory Distress Syndrome

2018
LncRNA analysis of lung tissues after hUC-MSCs and FTY720 treatment of lipopolysaccharide-induced acute lung injury in mouse models.
    International immunopharmacology, 2019, Volume: 71

    Topics: Acute Lung Injury; Animals; Combined Modality Therapy; Disease Models, Animal; Fingolimod Hydrochloride; Gene Expression Regulation; Gene Ontology; Humans; Immunosuppressive Agents; Lipopolysaccharides; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Pneumonia; RNA, Long Noncoding; Signal Transduction; Umbilical Cord

2019
FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury.
    Critical care medicine, 2014, Volume: 42, Issue:3

    Topics: Acute Lung Injury; Animals; Arrestins; beta-Arrestins; Bleomycin; Blotting, Western; Capillary Permeability; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Fingolimod Hydrochloride; Fluorescent Antibody Technique; Humans; Mice; Mice, Inbred C57BL; Propylene Glycols; Random Allocation; Receptors, G-Protein-Coupled; Receptors, Lysosphingolipid; Sensitivity and Specificity; Sphingosine

2014
FTY720 attenuates paraquat-induced lung injury in mice.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: Actins; Acute Lung Injury; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Disease Models, Animal; Fingolimod Hydrochloride; Interleukin-1beta; Interleukin-6; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Paraquat; Propylene Glycols; Pulmonary Edema; Pulmonary Fibrosis; Sphingosine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2014
A sphingosine-1 phosphate agonist (FTY720) limits trauma/hemorrhagic shock-induced multiple organ dysfunction syndrome.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:5

    Topics: Acute Lung Injury; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocyte Deformability; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Multiple Organ Failure; Neutrophil Activation; Propylene Glycols; Rats, Sprague-Dawley; Respiratory Burst; Shock, Hemorrhagic; Sphingosine

2014
Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate.
    Microvascular research, 2015, Volume: 99

    Topics: Acute Lung Injury; Antigens, CD; Antigens, Nuclear; Cadherins; Endothelial Cells; Fingolimod Hydrochloride; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Immunosuppressive Agents; Lung; Lysophospholipids; Microscopy, Fluorescence; Nerve Tissue Proteins; Organophosphonates; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; RNA, Small Interfering; Sphingosine; Transcription Factors; Zonula Occludens-1 Protein

2015