fingolimod hydrochloride has been researched along with Acute Confusional Senile Dementia in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 13 (59.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bechet, S; Dev, KK; Fagan, SG | 1 |
| Dąbrowska-Bouta, B; Strosznajder, R; Struzynska, L; Sulkowski, G; Wencel, PL | 1 |
| Berkes, D; Bieberich, E; Crivelli, SM; De Vries, HE; Dehairs, J; den Hoedt, S; Derua, R; Giovagnoni, C; Kruining, DV; Losen, M; Luo, Q; Mané-Damas, M; Martinez-Martinez, P; Mulder, MT; Swinnen, JV; Waelkens, E; Walter, J; Wijnands, EPM | 1 |
| Arnold, M; Baillie, R; Baloni, P; Brauner, B; Buitrago, L; Doraiswamy, PM; Ekroos, K; Funk, CC; Han, X; Hernández, AI; Hood, L; Huynh, K; Kaddurah-Daouk, R; Kastenmüller, G; Kueider-Paisley, A; Louie, G; Meikle, PJ; Moreno, H; Nho, K; Price, ND; Saykin, AJ; Suhre, K | 1 |
| Carreras, I; Dedeoglu, A; Jung, Y; Lopez-Benitez, J; Tognoni, CM | 1 |
| Bascuñana, P; Brackhan, M; Brüning, T; Eiriz, I; Jansone, B; Möhle, L; Pahnke, J; Wu, J | 1 |
| Endres, T; Gottmann, K; Kartalou, GI; Leßmann, V; Pawlitzki, M | 1 |
| Berg, AJ; Cai, Y; Cui, T; Lok, C; Morency, DT; Paganelli, PM; Vicini, S; Wang, T; Xue, Y; Yin, P | 1 |
| Jęśko, H; Lukiw, WJ; Strosznajder, J; Strosznajder, RP; Wencel, PL; Wójtowicz, S | 1 |
| Bascuñana, P; Brackhan, M; Möhle, L; Pahnke, J | 1 |
| Chen, CP; Chew, WS; Chua, XY; Herr, DR; Ho, LTY; Lai, MKP; Lam, BWS; Ong, WY; Xiang, P | 1 |
| Casarotto, P; Castrén, E; Delanoe, K; Edelmann, E; Endres, T; Gottmann, K; Kartalou, GI; Lesnikova, A; Lessmann, V; Marie, H; Pousinha, P; Salgueiro-Pereira, AR | 1 |
| Edelmann, E; Garad, M; Leßmann, V | 1 |
| Finucane, OM; Lynch, MA; McManus, RM; Mills, KHG; Wilk, MM | 1 |
| Jęśko, H; Lukiw, WJ; Strosznajder, RP; Wencel, PL | 1 |
| Angelopoulou, E; Piperi, C | 1 |
| Aytan, N; Carreras, I; Choi, JK; Dedeoglu, A; Jenkins, BG; Kowall, NW; Tognoni, CM | 1 |
| Ahmadiani, A; Chik, Z; Dargahi, L; Hemmati, F; Mohamed, Z; Naidu, M; Nasoohi, S; Omidbakhsh, R | 1 |
| Fukumoto, K; Horiuchi, H; Jin, S; Kawanokuchi, J; Mizoguchi, H; Mizuno, T; Suzumura, A; Takeuchi, H | 1 |
| Francolini, M; Joshi, P; Mastrangelo, R; Matteoli, M; Ruiz, A; Verderio, C | 1 |
| Ahmadiani, A; Asle-Rousta, M; Dargahi, L; Kolahdooz, Z; Nasoohi, S | 1 |
| Aytan, N; Brinkmann, V; Carreras, I; Choi, JK; Dedeoglu, A; Jenkins, BG; Kowall, NW | 1 |
4 review(s) available for fingolimod hydrochloride and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Repurposing drugs against Alzheimer's disease: can the anti-multiple sclerosis drug fingolimod (FTY720) effectively tackle inflammation processes in AD?
Topics: Aged; Alzheimer Disease; Animals; Drug Repositioning; Fingolimod Hydrochloride; Humans; Inflammation; Mice; Multiple Sclerosis; Sclerosis | 2023 |
Fingolimod as a Treatment in Neurologic Disorders Beyond Multiple Sclerosis.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Fingolimod Hydrochloride; Humans; Lymphocytes; Mice; Multiple Sclerosis; Nervous System Diseases; Neuroprotective Agents; Rats; Sphingosine 1 Phosphate Receptor Modulators | 2020 |
Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment.
Topics: Aldehyde-Lyases; Alzheimer Disease; Animals; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia, Vascular; Drug Delivery Systems; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Stroke; Lysophospholipids; Mice; Mice, Knockout; Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors | 2021 |
Beneficial Effects of Fingolimod in Alzheimer's Disease: Molecular Mechanisms and Therapeutic Potential.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Apoptosis; Blood-Brain Barrier; Brain-Derived Neurotrophic Factor; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Immunologic Factors; Inflammation; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroimmunomodulation; Neuroprotective Agents; Phosphotransferases (Alcohol Group Acceptor); Rats; Signal Transduction; Species Specificity; Sphingolipids; Sphingosine-1-Phosphate Receptors | 2019 |
18 other study(ies) available for fingolimod hydrochloride and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Fingolimod Rescues Memory and Improves Pathological Hallmarks in the 3xTg-AD Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Fingolimod Hydrochloride; Mice; Mice, Transgenic; tau Proteins | 2022 |
Alterations in the transcriptional profile of genes related to glutamatergic signalling in animal models of Alzheimer's disease. The effect of fingolimod.
Topics: Alzheimer Disease; Animals; Fingolimod Hydrochloride; Glutamic Acid; Mice; Models, Animal; Signal Transduction | 2022 |
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4.
Topics: Alzheimer Disease; Animals; Apolipoprotein E4; Brain; Ceramides; Disease Models, Animal; Fingolimod Hydrochloride; Humans; Memory Disorders; Mice; Sphingolipids | 2022 |
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Ceramides; Fingolimod Hydrochloride; Genome-Wide Association Study; Humans; Mice; Sphingolipids; Sphingomyelins | 2022 |
Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Fingolimod Hydrochloride; Lysophospholipids; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-akt; Sphingosine; Sphingosine-1-Phosphate Receptors; TOR Serine-Threonine Kinases | 2023 |
Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Fingolimod Hydrochloride; Male; Mice; Mice, Transgenic | 2023 |
Glial Sphingosine-Mediated Epigenetic Regulation Stabilizes Synaptic Function in
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Drosophila; Epigenesis, Genetic; Female; Fingolimod Hydrochloride; Histones; Male; Mice; Neuroglia; Neuronal Plasticity; Sphingosine | 2023 |
Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Ceramidases; Ceramides; Disease Models, Animal; Down-Regulation; Female; Fingolimod Hydrochloride; Hippocampus; Humans; Lipid Metabolism; Membrane Proteins; Mice; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Oxidoreductases; Transcription, Genetic; Transferases (Other Substituted Phosphate Groups) | 2020 |
Anti-Inflammatory Treatment with FTY720 Starting after Onset of Symptoms Reverses Synaptic Deficits in an AD Mouse Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Astrocytes; Disease Models, Animal; Fingolimod Hydrochloride; Hippocampus; Humans; Inflammation; Memory Disorders; Mice; Mice, Transgenic; Microglia; Presenilin-1; Synapses | 2020 |
Impairment of Spike-Timing-Dependent Plasticity at Schaffer Collateral-CA1 Synapses in Adult APP/PS1 Mice Depends on Proximity of Aβ Plaques.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Fingolimod Hydrochloride; Humans; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Mutation; Patch-Clamp Techniques; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Synapses | 2021 |
FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Bordetella Infections; Bordetella pertussis; Fingolimod Hydrochloride; Immunosuppressive Agents; Mice; Mice, Transgenic; Plaque, Amyloid; Presenilin-1 | 2017 |
Modulatory Effects of Fingolimod (FTY720) on the Expression of Sphingolipid Metabolism-Related Genes in an Animal Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Female; Fingolimod Hydrochloride; Gene Expression Regulation; Humans; Mice; RNA, Messenger; Sphingolipids | 2019 |
Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Disease Models, Animal; Drug Repositioning; Female; Fingolimod Hydrochloride; gamma-Aminobutyric Acid; Mice; Mice, Transgenic; Microglia; Neuroprotective Agents | 2019 |
Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: comparison with memantine.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fingolimod Hydrochloride; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; Male; Memantine; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroprotective Agents; Peptide Fragments; Propylene Glycols; Rats; Rats, Sprague-Dawley; Sex Factors; Sphingosine | 2013 |
Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Association Learning; Brain; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Exploratory Behavior; Fingolimod Hydrochloride; Hippocampus; Male; Memory Disorders; Mice, Inbred C57BL; Neuroprotective Agents; Peptide Fragments; Propylene Glycols; Recognition, Psychology; Sphingosine; Up-Regulation | 2014 |
Testing Aβ toxicity on primary CNS cultures using drug-screening microfluidic chips.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Dimethylpolysiloxanes; Embryo, Mammalian; Equipment Design; Fingolimod Hydrochloride; High-Throughput Screening Assays; Hippocampus; Microfluidic Analytical Techniques; Microglia; Neurons; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Printing, Three-Dimensional; Propylene Glycols; Protein Aggregation, Pathological; Rats; Shear Strength; Sphingosine; Surface Properties | 2014 |
Prominence of central sphingosine-1-phosphate receptor-1 in attenuating aβ-induced injury by fingolimod.
Topics: Alzheimer Disease; Animals; Cyclooxygenase 2; Enzyme Inhibitors; Fingolimod Hydrochloride; Male; Maze Learning; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Tumor Necrosis Factor-alpha | 2014 |
Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Brain; Disease Models, Animal; Fingolimod Hydrochloride; Mice; Treatment Outcome | 2016 |