finasteride has been researched along with Cancer of Prostate in 478 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 83 (17.36) | 18.2507 |
2000's | 231 (48.33) | 29.6817 |
2010's | 156 (32.64) | 24.3611 |
2020's | 8 (1.67) | 2.80 |
Authors | Studies |
---|---|
Belle, C; Cassiani, C; Comerci, A; Danza, G; De Bellis, A; Dini, S; Guarna, A; Machetti, F; Marrucci, A; Occhiato, EG; Payne, AH; Serio, M | 1 |
Brodie, AM; Grigoryev, DN; Kato, K; Long, BJ; Njar, VC; Nnane, IP | 1 |
Choi, EW; Fan, G; Kim, K; Kim, S; Mar, W; Park, MK | 1 |
Brodie, AM; Chopra, P; Farquhar, R; Gediya, LK; Guo, Z; Handratta, VD; Kataria, R; Newman, D; Njar, VC; Qiu, Y; Vasaitis, TS | 1 |
Bondesson, U; Hedeland, M; Lennernäs, H; Lundahl, A | 1 |
Bratoeff, E; Cabeza, M; Garrido, M; Heuze, Y; Ramírez-Apan, T; Sánchez, A; Soriano, J | 1 |
Alvarez-Manrique, B; Bratoeff, E; Cabeza, M; Cortés-Benítez, F; Ramírez-Apan, MT | 1 |
Chen, H; Deng, ZA; Lv, DJ; Qian, YN; Shen, JL; Tian, XM; Wang, CL; Yu, YZ; Yuan, M; Zhang, HB; Zhang, JX; Zhao, SC | 1 |
Chen, H; Hu, P; Li, J; Qian, Y; Shen, J; Zhang, J | 1 |
Chau, CH; Figg, WD; Goodman, PJ; Neuhouser, ML; Pollak, MN; Price, DK; Thompson, IM; Till, C | 1 |
Chan, CH; Chan, YS; Chiu, PK; Lau, SY; Leung, CH; Liu, AQ; Ng, CF; Poon, WT; Tang, WL; Teoh, JY; Yee, CH; Yuen, SK | 1 |
Medina, CA; Plata, M; Zuluaga, L | 1 |
Kramer, B; Tangen, CM; Thompson, IM | 1 |
Rose, BS; Sarkar, RR | 1 |
Ahmed, M; Cieza-Borrella, C; Eeles, R; Goh, C; Kote-Jarai, Z; Saunders, E; Schumacher, FR | 1 |
Chen, Y; Cui, D; Gao, Y; Lei, Y; Li, R; Tang, Q; Wang, D; Wang, H; Wang, L; Zhang, B | 1 |
Ahmed, HU; Arya, M; Day, E; Dobbs, C; Dudderidge, T; Emberton, M; Fiorentino, F; McCracken, S; Prevost, AT; Reddy, D; Shah, TT; Staffurth, J; Sydes, M; Winkler, M | 1 |
Boukovala, M; Brössner, C; Efstathiou, E; Gustafsson, JA; Spetsieris, N; Wang, L; Warner, M; Wu, WF | 1 |
Hu, H; Liang, G; Liu, Z; Yang, J; Yang, Y; Zhang, H; Zhao, F | 1 |
Loughlin, KR | 1 |
De Marzo, AM; Drake, CG; Goodman, PJ; Isaacs, WB; Johnson-Pais, TL; Leach, RJ; Lippman, SM; Lucia, MS; Parnes, HL; Platz, EA; Santella, RM; Tangen, CM; Thompson, IM; Till, C; Winchester, DA; Xu, J; Zheng, SL | 1 |
Gelfond, J; Kabra, A; Liss, MA | 1 |
Abate-Shen, C; Barbieri, CE; Cremers, S; Dutta, A; Golombos, DM; Kim, JY; Liu, D; Mitrofanova, A; Mosquera, JM; Mostaghel, EA; Panja, S; Virk, RK; Zott, R | 1 |
Álvarez-Véliz, S; Berroeta-Mauriziano, D; Carrasco-Zuber, JE; Carreño-Orellana, N; Moll-Manzur, C; Porras-Kusmanic, N | 1 |
Ben-Zvi, T; Bergeron, A; Caron, A; Dujardin, T; Fradet, V; Fradet, Y; Lacombe, L; Léger, C; Lévesque, J; Lodde, M; Nguile-Makao, M; Pouliot, F; Tiguert, R; Toren, P | 1 |
Liss, MA; Thompson, IM | 1 |
Ambrosone, CB; Figg, WD; Goodman, PJ; Hsing, A; Lippman, SM; Neuhouser, ML; Platek, ME; Platz, EA; Reichardt, JKV; Santella, RM; Stanczyk, FZ; Tang, L; Tangen, CM; Thompson, IM; Till, C; Wu, Y; Yao, S | 1 |
Kaplan, SA | 3 |
Ambrosone, C; Chu, LW; Goodman, PJ; Han, S; Hoque, AM; Hsing, AW; Leach, R; Tangen, CM; Thompson, I; Till, C; Yang, B; Yu, K; Zhu, Y | 1 |
Shah, SQ; Uddin, G | 1 |
Barlow, WE; Goodman, PJ; Hershman, DL; Ramsey, SD; Tangen, CM; Thompson, IM; Till, C; Unger, JM | 1 |
Fan, Y; Jarosek, SL; Konety, BR; Lawrentschuk, NL; Sathianathen, NJ | 1 |
Konety, BR; Sathianathen, NJ | 1 |
Resnick, MJ | 1 |
Ankerst, D; Gelfond, J; Goros, M; Hernandez, J; Leach, RJ; Liang, Y; Liss, MA; Thompson, IM | 1 |
Dai, JY; Goodman, PJ; LeBlanc, M; Lucia, MS; Tangen, CM; Thompson, IM | 1 |
Darke, AK; Ford, LG; Goodman, PJ; LeBlanc, ML; Lucia, MS; Minasian, LM; Parnes, HL; Tangen, CM; Thompson, IM | 1 |
Palm, S; Stapff, MP | 1 |
Garnick, MB | 1 |
Goodman, PJ; Tangen, CM; Thompson, IM | 2 |
Azen, CG; Pike, MC; Stanczyk, FZ | 1 |
Al Edwan, G; Fleshner, N | 1 |
Gomella, LG | 1 |
Eisermann, K; Ma, HM; Masoodi, KZ; Nelson, JB; Nguyen, HM; O'Malley, K; Parikh, RA; Pascal, LE; Ramos Garcia, R; Shevrin, DH; Vessella, RL; Wang, Y; Wang, Z | 1 |
Nambiar, D; Singh, RP | 1 |
Lu, X; Mehrotra, DV; Shepherd, BE | 1 |
Azzouni, F; Godoy, A; Ip, C; Mohler, JL; Wilton, JH; Wu, Y | 1 |
Cheng, J; Chhipa, RR; Halim, D; Ip, C; Mohler, JL; Wu, Y; Zhang, HY | 1 |
Morgentaler, A; Traish, AM | 1 |
Stanczyk, FZ | 1 |
Ford, LG; Godley, PA; Goodman, PJ; Lucia, MS; Minasian, LM; Parnes, HL; Tangen, CM; Thompson, IM | 1 |
LeFevre, M | 1 |
McCarthy, M | 1 |
Marchesi, V | 1 |
Payton, S | 1 |
Andriole, GL; Vemana, G | 1 |
Ankerst, DP; Boeck, A; Goodman, PJ; Tangen, CM; Thompson, IM; Till, C | 1 |
Andriole, GL; Freedland, SJ; Hamilton, RJ; Vemana, G | 1 |
Beck, AP; Henningson, JN; Lindshield, BL; Opoku-Acheampong, AB; Unis, D | 1 |
Walsh, PC | 5 |
Revannasiddaiah, S; Susheela, SP | 1 |
Rees, J | 1 |
Almeida, R; Deffune, E; Delella, FK; Fávaro, WJ; Felisbino, SL; Lacorte, LM; Moroz, A | 1 |
Taneja, SS | 1 |
Seftel, AD | 1 |
Bhargava, S | 1 |
Printz, C | 1 |
Babayan, RK | 1 |
Kristal, A; Platz, EA; Thompson, I | 1 |
Michel, MS; Nitschmann, S; von Hardenberg, J | 1 |
Arnold, KB; Burton-Chase, AM; Caggiano, V; Carlin, S; Goodman, PJ; Gritz, ER; Hill, S; Lieber, MM; Meyskens, FL; Minasian, LM; Moinpour, CM; Moody-Thomas, S; Padberg, RM; Probstfield, JF; Ryan, A; See, WA; Szczepanek, C; Tangen, CM; Thompson, IM | 1 |
Goodman, PJ; Kristal, AR; Neuhouser, ML; Peters, U; Schenk, JM; Song, X; Tangen, CM; Till, CA; Torkko, KC | 1 |
Andrew, R; Faqehi, AM; Homer, NZ; Hughes, KA; Naredo, G; Stewart, LH; Upreti, R; Walker, BR | 1 |
Cagnon, VH; Hetzl, AC; Kido, LA; Montico, F | 1 |
Ambrosone, CB; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Parnes, HL; Platz, EA; Price, DK; Reichardt, JK; Santella, RM; Stanczyk, FZ; Tangen, CM; Thompson, IM; Till, C; vanBokhoven, A; Yao, S | 1 |
Casabé, A; Glina, S; Henneges, C; Roehrborn, CG; Sorsaburu, S; Viktrup, L | 1 |
De Marzo, AM; Gaonkar, G; Goodman, PJ; Heaphy, CM; Joshu, CE; Lippman, SM; Lucia, MS; Meeker, AK; Peskoe, SB; Platz, EA; Thompson, IM | 1 |
Chau, CH; Chen, X; Chu, L; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Johnson-Pais, TL; Leach, RJ; Parnes, HL; Price, DK; Reichardt, JK; Schenk, JM; Tangen, CM; Thompson, IM; Till, C | 1 |
Azoulay, L; Benayoun, S; Eberg, M; Pollak, M | 1 |
Figg, WD; Thompson, IM | 1 |
Cagnon, VH; Kido, LA; Montico, F; Rowley, DR; San Martin, R | 1 |
Lippman, SM; Lucia, MS; Nash, SH; Parnes, HL; Platz, EA; Schenk, J; Song, X; Thompson, IM; Till, C | 1 |
Bortolato, M; Garcia-Segura, LM; Melcangi, RC; Traish, AM; Zitzmann, M | 1 |
Brant, WO; Darke, A; Hotaling, JM; Myers, JB; Patel, DP; Schenk, JM | 1 |
La Vecchia, C | 1 |
Cai, W; Guo, Y; Jiang, Y; Li, W; Wang, X; Yang, S | 1 |
Barber, JR; De Marzo, AM; Drake, CG; Goodman, PJ; Gurel, B; Kristal, AR; Lippman, SM; Lucia, MS; Murtola, TJ; Nelson, WG; Parnes, HL; Peskoe, SB; Platz, EA; Sutcliffe, S; Thompson, IM; Umbehr, M | 1 |
Ding, J; Duan, L; Qi, J; Qian, X; Xu, D; Zhu, Y | 1 |
Block, NL; Rick, FG | 1 |
Basler, JW; Brown, PH; Davis, JW; Do, KA; Efstathiou, E; Gorlov, IP; Hoque, AM; Kim, J; Klein, EA; Lee, JJ; Li Ning Tapia, EM; Lippman, SM; Logothetis, CJ; Lotan, Y; Magi-Galluzzi, C; Parnes, HL; Pettaway, CA; Pisters, LL; Prokhorova, IN; Stephenson, A; Thompson, IM; Troncoso, P; Vornik, LA; Wang, X; Ward, JF | 1 |
Arias-Santiago, S; Camacho-Martínez, FM | 1 |
Barlow, WE; Goodman, PJ; Hershman, DL; Minasian, LM; Ramsey, SD; Tangen, CM; Thompson, IM; Till, C; Unger, JM; Wright, JD | 1 |
Fan, D; Jin, S; Niu, Y; Wang, K; Wang, M; Xing, N | 1 |
Cohen, SI | 1 |
Chadha, VD; Dhawan, DK; Jan, G; Passi, ND | 1 |
Acevedo, C; Cabezas, J; Castellón, EA; Contreras, HR; Huidobro, C; Mendoza, P; Noé, G; Sánchez, C; Vergara, J | 1 |
Vastag, B | 1 |
Soloway, M | 1 |
Roobol, MJ; Schröder, FH; van den Bergh, RC; van Leeuwen, PJ; Wolters, T | 1 |
McBride, D | 1 |
Sarvis, JA; Thompson, IM | 2 |
Arnold, KB; Goodman, PJ; Kristal, AR; Lin, DW; Neuhouser, ML; Schenk, JM; Song, Y; Stanczyk, FZ; Thompson, IM | 1 |
Stattin, P; Wirén, S | 1 |
Altwein, J; Dörsam, J | 1 |
Bass, R; Dennis, KL; Holzbeierlein, J; Langenstroer, P; Perry, B; Tawfik, O; Thrasher, JB | 1 |
Logothetis, CJ; Schellhammer, PF | 1 |
Coltman, CA; Darke, AK; Ford, LG; Goodman, PJ; La Rosa, FG; Lucia, MS; Parnes, HL; Thompson, IM | 1 |
Coltman, CA; Goodman, PJ; Lucia, MS; Redman, MW; Tangen, CM; Thompson, IM | 1 |
Ford, L; Parnes, H; Pinsky, P | 1 |
Edwards, JL | 1 |
Adolfsson, J | 1 |
Eggener, S; Orvieto, M | 1 |
Fleshner, NE; Rittmaster, RS; Thompson, IM | 1 |
Bañez, LL; Blake, GW; Crawford, ED; McLeod, DG; Moul, JW | 1 |
Alcaraz, A; Castro, R; Desgrandchamps, F; Hammerer, P; Montorsi, F; Schröder, F | 1 |
Fitzpatrick, JM; Schröder, FH; Schulman, C; Zlotta, AR | 1 |
Parekh, DJ; Reed, AB | 1 |
Binkowitz, BS; Carides, AD; Heyden, NL; Kaplan, SA; Liu, KS; Meehan, AG; Roehrborn, CG; Vaughan, ED | 1 |
Andriole, GL | 1 |
Montie, JE | 1 |
Mitka, M | 1 |
Adomat, HH; Gleave, ME; Guns, ES; Hendy, SC; Locke, JA; Nelson, CC | 1 |
Kraljic, I; Kusic, Z; Spajic, B; Tarle, M | 1 |
Acquaro, C; Carvalho, RF; Felisbino, SL; Justulin, LA; Silva, MD | 1 |
Kim, J; Li, J | 1 |
Delella, FK; Felisbino, SL; Justulin, LA | 1 |
Elliott, CS; Presti, JC; Shinghal, R | 1 |
Gong, Z; Goodman, PJ; Kristal, AR; Schenk, JM; Tangen, CM; Thompson, IM | 1 |
Schröder, FH; Vis, AN | 1 |
Wyllie, MG | 1 |
Ala-Opas, M; Auvinen, A; Määttänen, L; Murtola, TJ; Stenman, UH; Tammela, TL | 1 |
Frankel, PH; Twardowski, P | 1 |
Gupta, S; Hua, V; Jovanovic, BD; Nelson, JB; Ramos-Garcia, R; Shevrin, D; Wang, Y; Wang, Z | 1 |
Keller, DL | 1 |
Dorff, TB; Leibowitz, RL; Symanowski, J; Tucker, S; Vogelzang, NJ | 1 |
Azzouzi, AR; Bigot, P; Lebdai, S | 1 |
Lilja, H; Savage, CJ; Vickers, AJ | 1 |
Abouassaly, R; Klein, EA; Stephenson, AJ | 1 |
Baker, SG; Darke, AK; Kramer, BS; Parnes, HL; Pinsky, P | 1 |
Albanes, D; Goodman, P; Hoque, A; Hsing, AW; Kristal, A; Neuhouser, ML; Parnes, HL; Platz, EA; Pollak, M; Till, C | 1 |
Bühler, P; Elsässer-Beile, U; Fischer, T; Gierschner, D; Schultze-Seemann, W; Wetterauer, U; Wolf, P | 1 |
Andriole, GL; Strope, SA | 1 |
Ambrosone, CB; Goodman, PJ; Hoque, A; Hsing, AW; Kappil, M; Kristal, A; Lucia, S; Parnes, H; Santella, RM; Tangen, C; Thompson, I; Till, C; Wang, Q | 1 |
Leahy, Y | 1 |
Hori, S; Ohtani, H; Satoh, H; Sawada, Y; Suzuki, R | 1 |
Blackwell, RH; Helfand, BT; McVary, KT | 1 |
Das, K; Lim, D; Lorena, PD; Ng, LK; Reichardt, JK; Salto-Tellez, M; Shen, L; Siow, WY; Teh, M | 1 |
Chaudhary, UB; Turner, JS | 1 |
Gupta, S; Nelson, JB; Ramos-Garcia, R; Shevrin, D; Wang, Y; Wang, Z | 1 |
Bruchovsky, N; Locke, JA | 1 |
Türkeri, L | 1 |
Diamandis, EP | 1 |
Pais, P | 1 |
Cui, L; Gao, JP; Hong, BF; Lü, XY; Xu, AX; Zhang, X; Zhu, J | 1 |
Mulders, PF; Pfeiffer, MJ; Schalken, JA | 1 |
Hamilton, RJ; Kahwati, LC; Kinsinger, LS | 1 |
Kim, ED; White, WM | 1 |
Bertele', V; Garattini, S | 1 |
Schmidt, LJ; Tindall, DJ | 1 |
Figg, WD; Hsing, AW; Hulin-Curtis, SL; Petit, D; Reichardt, JK | 1 |
Barry, MJ; Hoffman, RM; Roberts, RG | 1 |
Moul, JW; Reed, SD; Scales, CD; Schulman, KA; Stewart, SB; Sun, J; Xu, J | 1 |
Parekh, DJ | 1 |
Ambrosone, CB; King, IB; Kristal, AR; Neuhouser, ML; Platz, EA; Song, X; Thompson, IM; Till, C | 1 |
Gontero, P; Oderda, M; Richiardi, L; Tizzani, A; Zitella, A | 1 |
Albanes, D; Brasky, TM; Goodman, P; King, IB; Kristal, AR; Neuhouser, ML; Song, X; Thompson, IM; Till, C; White, E | 1 |
Arnold, KB; Kristal, AR; Lin, DW; Neuhouser, ML; Schenk, JM; Tangen, CM; Thompson, IM; White, E | 1 |
Ambrosone, CB; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Parnes, HL; Platz, EA; Price, DK; Reichardt, JK; Santella, RM; Stanczyk, FZ; Tang, L; Tangen, CM; Thompson, IM; Till, C; Yao, S | 1 |
Justice, R; Keegan, P; Ning, YM; Pazdur, R; Theoret, MR; Zhang, JJ | 1 |
Alberts, DS; Bartels, HG; Bartels, PH; Carmignani, G; DeCensi, A; Decobelli, O; Hurle, R; Maffezzini, M; Mazzucchelli, R; Montironi, R; Puntoni, M | 1 |
Bhardwaj, TR; Dhingra, N; Kumar, A; Kumar, M; Mehta, N; Mukhopadhyay, T | 1 |
Wirth, M; Zastrow, S | 1 |
Freedland, SJ; Hamilton, RJ | 1 |
Bismarck, E; Fischer, C; Lümmen, G; Schmitz-Dräger, BJ | 1 |
Justman, S | 1 |
Ahles, T; Gu, L; Halabi, S; Hussain, A; Kaplan, E; Kelly, WK; Monk, JP; Philips, G; Picus, J; Small, EJ; Vogelzang, N | 1 |
Lindshield, BL; Nelsen, MK; Opoku-Acheampong, AB; Unis, D | 1 |
Byrns, MC; Duan, L; Mindnich, R; Penning, TM | 1 |
Carter, HB; Feng, Z; Landis, P; Pierorazio, PM; Ross, AE; Schaeffer, EM; Trock, BJ; Walsh, PC | 1 |
Bubley, G; Dumas, C; Slater, S | 1 |
Cvijetić, S; Dodig, S; Jurasović, J; Milković-Kraus, S; Mück-Šeler, D; Mustapić, M; Pašalić, D; Pauković, P; Pavlović, M; Pivac, N; Pizent, A | 1 |
Azzouni, F; Mohler, J | 1 |
Camarena-Reynoso, HR; Jimenez-Rios, MA; Ketchum, NS; Liang, Y; Louden, C; Thompson, IM | 1 |
Chiba, Y | 1 |
Bismarck, E; Fischer, C; Schmitz-Dräger, BJ; Schöffski, O | 1 |
Chang, SN; Kao, CH; Liang, JA; Lin, MC; Muo, CH; Sun, LM; Sung, FC | 1 |
Paller, CJ; Smith, TJ | 1 |
Moul, JW; Reed, SD; Scales, CD; Stewart, SB | 1 |
De Marzo, AM; Gaydos, CA; Goodman, PJ; Hoque, AM; Hsing, AW; Jenkins, FJ; Nelson, WG; Platz, EA; Sutcliffe, S; Thompson, IM; Till, C; Zenilman, JM | 1 |
Chung, DE; Kaplan, SA; Lee, RK; Scherr, DS; Te, AE; Tewari, A; Vaughan, ED | 1 |
Ehdaie, B | 1 |
Chu, LW; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Patel, SK; Platz, EA; Reichardt, JK; Stanczyk, FZ; Tangen, CM; Thompson, IM; Till, C; Van Bokhoven, A | 1 |
Cespedes, D; Darke, AK; Donaldson, GW; Ganz, PA; Johnson, CR; Meyskens, FL; Moinpour, CM; Patrick, DL; Shumaker, SA; Thompson, IM; Ware, JE | 1 |
Damjanoski, I; Küfer, R; Müller, J; Rinnab, L; Schnöller, TJ | 1 |
Akre, O; Friis, S; Granath, F; Gustafsson, O; Kjellman, A; Sørensen, HT | 1 |
Dunn, BK; Greenwald, P; Umar, A | 1 |
Andriole, GL; Nepple, KG | 1 |
Autorino, R; Berardinelli, F; Cindolo, L; Fanizza, C; Pirozzi, L; Romero, M; Schips, L | 1 |
Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, A; Lucia, MS; Neuhouser, ML; Parnes, HL; Platz, EA; Pollak, M; Tangen, CM; Tao, Y; Thompson, IM; Till, C | 1 |
Kujala, PM; Murtola, TJ; Tammela, TL | 1 |
Fromer, D; Ghafar, MA; Kaplan, SA; Lam, JS; Te, AE; Volpe, MA | 1 |
Tisman, G | 1 |
Bladou, F; Chartier-Kastler, E; Chautard, D; Coloby, P; Desgrandchamps, F; Fontaine, E; Haillot, O; Irani, J; Lechevallier, E; Pariente, JL; Ravery, V; Soulie, M | 1 |
Anderson, WR; Harris, NM; Holmes, SA | 1 |
Crowley, JJ; Goodman, PJ; Gower, KB; Pauler, DK; Thompson, IM | 1 |
Bahnson, R; Bissonette, EA; Miller, NL; Theodorescu, D; Wilson, J | 1 |
Grönberg, H | 1 |
Klein, EA | 2 |
Jacobsen, SJ; Roberts, RO | 1 |
Fitzpatrick, JM | 2 |
Bissonette, EA; Krupski, T; Petroni, GR; Theodorescu, D | 1 |
Derksen, JE; Gaston, K; Pruthi, RS | 1 |
Scardino, PT | 1 |
Atkins, JN; Carlin, SM; Cespedes, RD; Coltman, CA; Crowley, JJ; Ford, LG; Goodman, PJ; Lieber, MM; Lippman, SM; Lucia, MS; Miller, GJ; Ryan, A; Szczepanek, CM; Tangen, CM; Thompson, IM | 1 |
Bittmann, L; Brufsky, A; Kantoff, PW; Kaplan, ID; Kaufman, DS; Manola, J; Oh, WK; Smith, MR | 1 |
Reynolds, T | 3 |
Zuger, A | 1 |
O'Reilly, P | 1 |
Levenson, D | 1 |
Dunn, TA; Ewing, CM; Isaacs, WB; Luo, J; Walsh, PC | 1 |
Thompson, CA | 1 |
Beer, TM | 1 |
Kantoff, PW; Rubin, MA | 2 |
Barzell, WE | 1 |
Roehrborn, CG | 1 |
Ellis, RJ; Lee, SC | 2 |
Burke, HB | 1 |
Cote, RJ; Ross, RK; Skinner, E | 1 |
Schwartz, DT | 1 |
Adolfsson, J; Borkowski, A; Fitzpatrick, J; Kirk, D; Marberger, M; Prezioso, D; Rabaça, C; Solsona, E; Teillac, P | 1 |
Barqawi, AB; Crawford, ED; Handel, L; Moul, JW; Ziada, A | 1 |
Coltman, CA; Djavan, B; Klein, EA; Lippman, SM; Thompson, IM | 1 |
Bartsch, G; Boccon Gibod, L; Djavan, B; Iversen, P; Marberger, M; Schulman, C; Teillac, P; Zlotta, A | 1 |
Higgins, B; Thompson, IM | 1 |
Douglas, RC; Lazier, CB; Rittmaster, RS; Thomas, LN; Vessey, JP | 1 |
Hellerstedt, B | 1 |
Barqawi, A; Crawford, ED; Gamito, E; O'Donnell, C | 1 |
Carlin, SM; Coltman, CA; Crowley, JJ; Ford, LG; Goodman, PJ; Ryan, A; Tangen, CM; Thompson, IM | 1 |
Lee, D | 1 |
Djavan, B; Michel, MS; Seitz, C; Thompson, I; Waldert, M | 1 |
Rannikko, A; Ruutu, M | 1 |
Klein, EA; Thompson, IM | 1 |
Reddy, GK | 1 |
Bostwick, DG; Civantos, F; Montironi, R; Qian, J; Roehrborn, CG | 1 |
Ferrari, AC; McCarron, JP; Mencher, SK; Wang, LG | 1 |
Pitts, WR | 6 |
Bott, SR; Foley, CL; Kirby, RS; Shergill, IS | 1 |
Febbo, PG; George, DJ; Kantoff, PW; Kaplan, ID; Kaufman, DS; Leibowitz, SB; Manola, J; Oh, WK; Regan, MM; Smith, MR; Tay, MH | 1 |
Coltman, CA; Crawford, ED; Crowley, JJ; Ford, LG; Goodman, PJ; Lippman, SM; Lucia, MS; Minasian, LM; Parnes, HL; Pauler, DK; Tangen, CM; Thompson, IM | 1 |
Cahlon, O; Cesaretti, JA; Kollmeier, MA; Stock, RG; Stone, NN | 1 |
Hausmann, R; Reich, O; Steif, CG; Thalmann, G | 1 |
Zielinski, SL | 1 |
Chapman, K; Habib, FK; Ho, CK; Lyons, V; Ross, M | 1 |
Brodie, AM; Handratta, VD; Jelovac, D; Kataria, R; Long, BJ; Njar, VC; Nnane, IP | 1 |
Barud, W; Palusinski, R | 1 |
Gustafsson, JA; Imamov, O; Lopatkin, NA | 1 |
Ford, LG; Parnes, HL; Thompson, IM | 1 |
Barassin, C; Dossou, U; Hartmann, RW; Kang, MJ; Mathur, S; Picard, F; Seidel, SB | 1 |
Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Vicentini, C | 1 |
Fourcade, RO | 1 |
Schulman, C | 1 |
Levinson, A; Lowe, FC; Nagler, EA | 1 |
Carver, BS; Eastham, JA; Kattan, MW; Scardino, PT | 1 |
Kakizoe, T | 1 |
Iwasaki, M; Tsugane, S | 1 |
Coltman, CA; Crowley, JJ; Ford, LG; Goodman, PJ; LeBlanc, M; Thompson, IM; Unger, JM | 1 |
Cadeddu, JA; Lee, JJ; Lippman, SM; Lotan, Y; Roehrborn, CG | 1 |
Bissonette, E; Miller, N; Smolkin, ME; Theodorescu, D | 1 |
Hutson, T; Mariani, S; Price, N; Sartor, O | 1 |
Hampton, T | 1 |
Benli, K; Bulut, S; Gökkaya, S; Memiş, A; Ozdal, OL; Ozden, C | 1 |
Etzioni, R; Kristal, AR; Zeliadt, SB | 1 |
Chen, G; Geng, J; Zhang, YF | 1 |
Mellon, JK | 1 |
Etzioni, RD; Penson, DF; Ramsey, SD; Thompson, IM; Zeliadt, SB | 1 |
Ankerst, DP; Etzioni, RD; Goodman, PJ; Howlader, N; Penson, DF; Shaw, PA; Thompson, IM | 1 |
Allory, Y; Cochand Priollet, B; de la Taille, A; Leroy, X; Molinié, V; Paraf, F; Ruffion, A | 1 |
Hakenberg, OW; Wirth, MP | 1 |
Goodman, PJ; Klein, EA; Lippman, SM; Tangen, CM; Thompson, IM | 1 |
Talcott, JA | 1 |
Canby-Hagino, ED; Thompson, IM | 1 |
Andriole, G; Bostwick, D; Civantos, F; Epstein, J; Lucia, MS; McConnell, J; Roehrborn, CG | 1 |
Abbou, C; Allory, Y; Cussenot, O; de la Taille, A; Faucon, H; Huang, W; Kuten, A; Leroy, X; Molinié, V; Rebillard, X; Rubin, MA; Salomon, L; Vacherot, F | 1 |
Ai, J; Cai, X; Eggener, SE; Jain, PM; Oram, S; Roehl, KA; Stern, JA; Wang, Z | 1 |
Leisinger, HJ; Wisard, M | 1 |
Coupal, L; Grover, S; Hajek, D; Lowensteyn, I; Marchand, S; Trachtenberg, J | 1 |
Federman, DG | 1 |
Frazee, LA; Lowe, JF | 1 |
Herman, ZS; Krysiak, R; Okopień, B; Szkróbka, W | 1 |
Carroll, PR; Cowan, JE; DuChane, J; Elkin, EP; Kawakami, J; Latini, DM | 1 |
Guess, BW; Jennrich, RI; Johnson, HJ; Lam, RY; Scholz, MC; Strum, SB | 1 |
Brand, TC; Canby-Hagino, ED; Hernandez, J; Thompson, IM | 1 |
Atiemo, H; Borkowski, A; Jacobs, SC; Kyprianou, N; Sutton, MT; Vyas, A; Yingling, M | 1 |
Becker, RE; Dalrymple, SL; Denmeade, SR; Isaacs, JT; Xu, Y | 1 |
Lee, JJ; Lippman, SM; Lotan, Y; Roehrborn, CG; Svatek, RS | 2 |
Goetzl, MA; Holzbeierlein, JM | 1 |
Fleshner, N; Kulkarni, G | 1 |
Bankhead, C | 1 |
Ankerst, DP; Chi, C; Coltman, CA; Goodman, PJ; Lippman, SM; Lucia, MS; Parnes, HL; Tangen, CM; Thompson, IM | 1 |
Ammar, H; Gupta, C; Malani, AK | 1 |
Figg, WD; Parnes, HL | 1 |
Brand, TC; Canby-Hagino, E; Hernandez, J; Thompson, I | 1 |
Hamdy, FC | 1 |
Albanes, D; Chi, C; Gong, Z; Goodman, PJ; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Platz, EA; Pollak, MN; Thompson, IM | 1 |
Bratoeff, E; Cabeza, M; Gracia, I; Heuze, I; Ochoa, M; Pérez, V; Ramírez, E; Ramírez-Apan, T; Rojas, A; Terán, N | 1 |
Barry, MJ; D'Amico, AV | 1 |
Hoque, A | 1 |
Agarwal, S; Cohen, SI; Handel, LN; Kelty, PJ; Schiff, SF | 1 |
Auvinen, A; Hakama, M; Määttänen, L; Murtola, TJ; Tammela, TL | 1 |
Ankerst, DP; Thompson, IM | 2 |
Grogg, AL; Issa, MM; Runken, MC; Shah, MB | 1 |
Hara, N; Labrie, F; Nishiyama, T; Suzuki, K; Takahashi, K; Yamana, K | 1 |
Gescher, AJ; Jain, S; Marczylo, TH; Mellon, JK; Steward, WP; Thorpe, JF | 1 |
Dunn, BK; Ford, LG | 1 |
Coltman, CA; Goodman, PJ; Lippman, SM; Lucia, MS; Parnes, HL; Tangen, CM; Thompson, IM | 1 |
Asamoto, M; Cho, YM; Shirai, T; Suzuki, S; Takahashi, S; Tang, M | 1 |
Matthews, PA | 1 |
Lümmen, G; Schäfer, RM; Schmitz-Dräger, BJ | 1 |
Coltman, CA; Darke, A; La Rosa, FG; Lippman, SM; Lucia, MS; Parnes, HL; Redman, MW; Thompson, IM | 1 |
Vale, S | 1 |
Benaim, E; Rittmaster, R; Roehrborn, CG; Serfling, R; Shulman, M; Thompson, GL; Xiao, Z | 1 |
Jewett, MA; Klotz, LH | 1 |
Thompson, IM | 1 |
Ankerst, DP; Coltman, CA; Darke, AK; Donaldson, GW; Ganz, PA; Langley, C; Lippman, SM; Moinpour, CM; Patrick, DL; Shumaker, SA; Thompson, IM; Ware, JE | 1 |
de Vere White, RW | 1 |
Chi, C; Coltman, CA; Goodman, PJ; Lippman, SM; Lucia, MS; Parnes, HL; Pauler Ankerst, D; Tangen, CM; Thompson, IM | 1 |
Andriole, GL; Grubb, RL; Humphrey, PA; Serfling, RJ | 1 |
Anderson, KM; Carides, AD; Cohen, YC; Daifotis, AG; Gann, PH; Heyden, NL; Liu, KS | 1 |
Civantos, F; Coltman, CA; Crawford, ED; Darke, AK; Epstein, JI; Ford, LG; Goodman, PJ; Kattan, MW; La Rosa, FG; Lippman, SM; Lucia, MS; Parnes, HL; Reuter, VE; Tangen, CM; Thompson, IM | 1 |
Bismarck, E; Dörsam, HJ; Fischer, C; Lümmen, G; Schmitz-Dräger, BJ | 1 |
Douglas, RC; Lazier, CB; Rittmaster, RS; Thomas, LN; Tindall, DJ; Too, CK | 1 |
Hernandez, J; Hudak, SJ; Thompson, IM | 1 |
Goodman, P; Kristal, AR; Lucia, MS; Parnes, HL; Song, Y; Tangen, C; Thompson, IM | 1 |
Arnold, KB; Goodman, P; Kristal, AR; Neuhouser, ML; Penson, DF; Schenk, JM; Thompson, IM | 1 |
Rittmaster, RS; Tindall, DJ | 1 |
Helling, TJ | 1 |
Clarke, N; Koltz, L | 1 |
Lucia, MS; Tangen, CM; Thompson, IM | 1 |
Golbano, JM; Lóppez-Aparicio, P; Pérez-Albarsanz, MA; Recio, MN | 1 |
Chen, X; Figg, WD; Gardner, ER; Price, DK | 1 |
Hagerty, K; Kramer, BS; MacDonald, R; Schellhammer, P; Wilt, TJ | 1 |
Hamdy, FC; Rouprêt, M | 1 |
Irani, J | 2 |
Allory, Y; Molinié, V | 1 |
de la Taille, A | 1 |
Villers, A | 1 |
Coltman, CA; Lippman, SM; Parnes, HL; Tangen, CM; Thompson, IM | 1 |
Barry, MJ; Kaufman, DS; Wu, CL | 1 |
Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Vicentini, C | 1 |
Gormley, GJ; Guess, HA; Oesterling, JE; Stoner, E | 1 |
Droz, JP | 1 |
Rittmaster, RS | 1 |
Fleshner, NE; Trachtenberg, J | 2 |
Klee, GG; Oesterling, JE; Ruckle, HC | 1 |
Cook, T; Gormley, GJ; Guess, H; Ng, J; Stoner, E; Walsh, P | 1 |
Konen, JC | 1 |
Stoner, E | 1 |
Ferguson, D; Gormley, GJ; Round, E; Stoner, E | 1 |
Schröder, FH | 1 |
Appell, RA | 1 |
Andriole, G; Boake, R; Crawford, D; DeKernion, J; Kadmon, D; Lieber, M; Rajfer, J; Schroeder, F; Smith, J; Soloway, M | 1 |
Schlegel, PN | 1 |
Blumenstein, B; Brawley, OW; Coltman, CA; Crowley, J; Feigl, P; Ford, LG; Kramer, BS; Thompson, I; Wolf, M | 1 |
Alberts, DS; Boone, CW; Covey, JM; Crowell, JA; Doody, LA; Greenwald, P; Kelloff, GJ; Knapp, GG; Lubet, RA; Steele, VE | 1 |
Brawley, OW; Coltman, CA; Ryan, A; Thompson, IM | 1 |
Coltman, C; Feigl, P; Thompson, I | 1 |
Alberti, C | 1 |
Akaza, H; Ideyama, Y; Imada, S; Koiso, K; Kudo, M; Shirai, T; Tsukamoto, S | 1 |
Greco, KE; Kulawiak, L | 1 |
Biordi, L; Bologna, M; Festuccia, C; Muzi, P; Vicentini, C | 1 |
Geller, J | 1 |
Brawley, OW; Ford, LG; Johnson, KA; Kramer, BS; Nayfield, SG; Perlman, JA | 1 |
Délos, S; Iehlé, C; Martin, PM; Raynaud, JP | 1 |
Brawley, OW; Thompson, IM | 2 |
Henderson, BE; Pike, MC; Ross, RK | 1 |
Brawley, O; Gormley, GJ; Thompson, I | 1 |
Carsol, JL; Délos, S; Ghazarossian, E; Martin, PM; Raynaud, JP | 1 |
Gormley, GJ | 4 |
Trachtenberg, J | 1 |
Coltman, CA; Thompson, IM | 1 |
Audia, JE; Bruchovsky, N; Goode, RL; Hsiao, KC; Kaefer, M; Krushinski, JH; Lee, C; Leibovitch, IY; Neubauer, BL; Steidle, CP; Sutkowski, DM | 1 |
Hiipakka, RA; Kokontis, JM; Liao, S; Umekita, Y | 1 |
Brawley, OW; Cheson, BD; Phillips, PH | 1 |
Andriole, GL; Charlton, ET; Johnson, B; Ornstein, DK; Rao, GS | 1 |
Bartels, PH; Diamanti, L; Hamilton, PW; Montironi, R; Pomante, R; Thompson, D | 1 |
Fair, WR; Fleshner, NE | 1 |
di Salle, E; Giudici, D; Zaccheo, T | 2 |
Nukui, F | 1 |
Berlane, K; Brufsky, A; Fontaine-Rothe, P; Jiroutek, M; Kantoff, P; Kaplan, I; Kaufman, D; Rieker, P | 1 |
Johnson, H; McDermed, JE; Scholz, MC; Strum, SB; Tisman, G | 1 |
Agha, A; Bach, M; Gormley, G; Johansen, T; Krarup, T; Lagerkvist, M; Oesterling, JE; Roy, J; Shown, T; Waldstreicher, J | 2 |
Kaisary, AV; Matveev, VB; Sandhu, SS | 1 |
Coltman, CA; Crowley, J; Thompson, IM | 1 |
Lowe, FC; Staiman, VR | 1 |
Akaza, H; Ideyama, Y; Onozawa, M; Shirai, T; Tsukamoto, S | 1 |
Allerton, J; Coltman, CA; Higgins, B; Lovato, L; Optenberg, S; Seay, T; Thompson, I | 1 |
Schulman, CC; Zlotta, AR | 1 |
Andriole, GL; Cook, TJ; Crawford, ED; Epstein, JI; Guess, HA; Hudson, P; Jackson, CL; Kadmon, D; Patterson, L; Romas, NA; Waldstreicher, J; Wise, H | 1 |
Cote, RJ; Henderson, BE; Mertes, SJ; Pike, MC; Ross, RK; Salem, CE; Skinner, EC; Stanczyk, FZ | 1 |
Brodie, A; Kato, K; Ling, YZ; Liu, Y; Lu, Q; Nnane, IP; Wang, X | 1 |
Andriole, GL; Ornstein, DK; Smith, DS | 1 |
Baumann, LS; Kelso, EB | 1 |
Litwin, MS | 1 |
Chapman, B | 1 |
Bannow, J; Epstein, JI; Fitch, WP; Gottesman, J; Hodge, GB; Lecksell, K; Parra, R; Peterson, L; Rouse, S; Schellhammer, PF; Short, K; Waldstreicher, J; Yang, XJ | 1 |
Andriole, GL; Beiser, JA; Ornstein, DK | 1 |
Coltman, CA; Feigl, P; Thompson, IM | 1 |
Altwein, J; Boyle, P; Denis, LJ; Griffiths, K; Kirby, R; Robertson, C; Schröder, F; Turkes, A | 1 |
Bostwick, DG | 1 |
Andriole, GL; Bhayani, SB | 1 |
Bostwick, DG; Cheng, L; Ramnani, D | 1 |
Bergner, D; Boyle, P; Bracken, RB; deVere White, R; Gittelman, M; Gray, T; Melman, A; Roehrborn, CG; Shown, T; Taylor, A; Waldstreicher, J; Wang, D | 1 |
Bartels, PH; Duval da Silva, V; Mazzucchelli, R; Montironi, R; Pomante, R; Thompson, D; Vaught, L | 1 |
Ehren-van Eekelen, C; Helin, H; Kallioniemi, OP; Koivisto, PA; Schleutker, J; Trapman, J | 1 |
Brawley, OW; Parnes, H | 1 |
Denis, LJ; Griffiths, K | 1 |
Bruchovsky, N; Crook, JM; Gleave, ME; Godwin, L; Goldenberg, SL; Hoffart, D; Klotz, LH; Sadar, M; Warkentin, M | 1 |
Calvert, RC; Mikhailidis, DP; Morgan, RJ; Thompson, CS | 1 |
Brodie, AM; Grigoryev, DN; Ling, YZ; Liu, Y; Long, BJ; Nnane, IP | 1 |
Atkinson, JO; Coltman, CA; Deantoni, E; Gritz, ER; Harvey, C; Hill, MS; Lovato, LC; Moinpour, CM; Parzuchowski, J; Ryan, AM; Thomas, SM; Thompson, IM; Underwood, SM | 1 |
Margiotti, K; Novelli, G; Reichardt, JK; Sangiuolo, F | 1 |
Nelson, WG; Wilding, G | 1 |
Kolvenbag, G; Neubauer, BL; Trump, DL; Waldstreicher, JA; Wissel, PS | 1 |
Coltman, CA; Goodman, P; Klein, EA; Kouril, M; Ryan, A; Thompson, IM | 1 |
Leibowitz, RL; Tucker, SJ | 1 |
Stephenson, J | 1 |
Broering, JM; Carroll, PR; Grossfeld, GD; Latini, D; Lubeck, DP; Small, EJ | 1 |
Lieberman, R | 1 |
Brooks, JD; DePrimo, SE; Shinghal, R; Vidanes, G | 1 |
Goodman, PJ; Kristal, AR; Neuhouser, ML; Patterson, RE; Thompson, IM | 1 |
Amin, P; Chen, T; Dawson, N; Engstrom, C; Hussain, A; Naslund, M | 1 |
Steers, WD | 1 |
Campbell, PE; Charles, GM; Cooke, DB; D'Agustino, JL; Deleon, M; Guillory, BO; Jackson, BA; Johnson, DE; Johnson, KP; Matthews, QL; McKay, J; Rowe, GC; Verret, CR; Williams, MV | 1 |
Barnes, S; Brawley, OW; Parnes, H | 1 |
Reid-Pitts, W | 1 |
Geller, J; Sionit, L | 1 |
Crawford, ED; DeAntoni, EP; Fair, WR; Kelloff, GJ; Lieber, MM; Miller, GJ; Scardíno, PT | 1 |
Andriole, G; Fair, WR; Ferguson, D; Gormley, GJ; Ng, J; Presti, JC; Seidmon, EJ; Sogani, PC | 1 |
Fiorelli, G; Serio, M | 1 |
Jenks, S | 1 |
Berman, C; Brooks, JR; Nguyen, H; Prahalada, S; Primka, RL; Rasmusson, GH; Slater, EE | 1 |
104 review(s) available for finasteride and Cancer of Prostate
Article | Year |
---|---|
Association of finasteride with prostate cancer: A systematic review and meta-analysis.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2020 |
5α-Reductase Inhibitors Could Prevent the Clinical and Pathological Progression of Prostate Cancer: A Meta-analysis.
Topics: 5-alpha Reductase Inhibitors; Disease Progression; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms | 2021 |
The clinical applications of five-alpha reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2021 |
[Finasteride adverse effects: An update].
Topics: 5-alpha Reductase Inhibitors; Alopecia; Blood Glucose; Erectile Dysfunction; Finasteride; Humans; Lipid Metabolism; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Spermatogenesis | 2016 |
Prostate cancer prevention with 5-alpha reductase inhibitors: concepts and controversies.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Dihydrotestosterone; Dutasteride; Early Detection of Cancer; Finasteride; Humans; Male; Organ Size; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Receptors, Androgen; Risk Factors | 2018 |
Advances in prostate cancer chemoprevention: a translational perspective.
Topics: Androgen Antagonists; Animals; Anticarcinogenic Agents; Antioxidants; Azasteroids; Carotenoids; Chemoprevention; Clinical Trials as Topic; Curcumin; Disease Models, Animal; Dutasteride; Finasteride; Flavonoids; Genistein; Humans; Lycopene; Male; Phytochemicals; Polyphenols; Prostate; Prostatic Neoplasms; Risk Factors; Selenium; Silybin; Silymarin; Tea; Vitamin E | 2013 |
Chemoprevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Azasteroids; Carotenoids; Dietary Supplements; Dutasteride; Finasteride; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Lycopene; Male; Plant Extracts; Primary Prevention; Prostatic Neoplasms; Selective Estrogen Receptor Modulators; Selenium; Serenoa; Vitamin E | 2014 |
Prevention of prostate cancer: outcomes of clinical trials and future opportunities.
Topics: Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Finasteride; Humans; Inflammation; Male; Middle Aged; Prostatic Neoplasms; Selenium; Treatment Outcome; Vitamin E | 2014 |
Adverse effects of 5α-reductase inhibitors: What do we know, don't know, and need to know?
Topics: 5-alpha Reductase Inhibitors; Alopecia; Animals; Central Nervous System; Cholestenone 5 alpha-Reductase; Cognition Disorders; Depression; Diabetes Mellitus; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Psychoses, Substance-Induced; Sexual Dysfunction, Physiological; Steroids | 2015 |
Prostate cancer chemoprevention: update of the prostate cancer prevention trial findings and implications for clinical practice.
Topics: Aged; Chemoprevention; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Placebos; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Risk; Sexual Dysfunction, Physiological | 2008 |
Androgens and prostate cancer risk.
Topics: Androgens; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2008 |
5alpha-Reductase inhibitor treatment of prostatic diseases: background and practical implications.
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents; Azasteroids; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2009 |
Pharmacological approaches to reducing the risk of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Age Factors; Aged; Azasteroids; Chemoprevention; Diet; Dutasteride; Early Detection of Cancer; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Incidence; Life Style; Male; Middle Aged; Primary Prevention; Prostatic Neoplasms; Risk Assessment | 2009 |
A broader role for 5ARIs in prostate disease? Existing evidence and emerging benefits.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Aging; Azasteroids; Dihydrotestosterone; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Sulfonamides; Tamsulosin; Testosterone; Urinary Tract Infections | 2009 |
Prostate cancer: a serious disease suitable for prevention.
Topics: Aged; Azasteroids; Cholestenone 5 alpha-Reductase; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors; Selenium; Toremifene; Vitamin E | 2009 |
The utility of 5-alpha reductase inhibitors in the prevention and diagnosis of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Biopsy; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2009 |
Overview of pivotal studies for prostate cancer risk reduction, past and present.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Clinical Trials as Topic; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2009 |
Molecular profiles of finasteride effects on prostate carcinogenesis.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgens; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Epithelial Cells; Finasteride; Humans; Isoenzymes; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Patient Selection; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Stromal Cells | 2009 |
Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5alpha-reductase.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Receptor Antagonists; Antineoplastic Agents, Hormonal; Azasteroids; Clinical Trials as Topic; Dutasteride; Finasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms | 2009 |
High-grade prostate cancer and finasteride.
Topics: 5-alpha Reductase Inhibitors; Aged; Antineoplastic Agents; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prevalence; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 2010 |
Chemoprevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Chemoprevention; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Primary Prevention; Prostatic Neoplasms; Risk Factors | 2010 |
Update on chemoprevention for prostate cancer.
Topics: Azasteroids; Chemoprevention; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Risk Factors; Vitamins | 2010 |
Finasteride.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2010 |
Steroid 5 α-reductase inhibitors targeting BPH and prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Clinical Trials as Topic; Dutasteride; Finasteride; Humans; Male; Molecular Structure; Prostatic Hyperplasia; Prostatic Neoplasms | 2011 |
Finasteride metabolism and pharmacogenetics: new approaches to personalized prevention of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Cytochrome P-450 CYP3A; Finasteride; Genetic Variation; Glucuronosyltransferase; Humans; Male; Precision Medicine; Prostatic Neoplasms; Testosterone | 2010 |
Prostate cancer prevention with 5 alpha-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Digital Rectal Examination; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2011 |
[Prostate cancer. Current and practice-relevant news from urology in 2011].
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Azasteroids; Biopsy; Combined Modality Therapy; Dutasteride; Finasteride; Guideline Adherence; Humans; Male; Middle Aged; Neoplasm Grading; Prognosis; Prostate; Prostatectomy; Prostatic Neoplasms; Survival Rate | 2011 |
[Primary prevention of urologic tumors: prostate cancer].
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Dutasteride; Feeding Behavior; Finasteride; Humans; Male; Micronutrients; Nutritional Requirements; Primary Prevention; Prostatic Neoplasms; Risk Factors; Treatment Outcome; Vitamins | 2011 |
Dutasteride for the treatment of prostate-related conditions.
Topics: 5-alpha Reductase Inhibitors; Animals; Antineoplastic Agents, Hormonal; Azasteroids; Dutasteride; Evidence-Based Medicine; Finasteride; Humans; Male; Patient Selection; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Assessment; Risk Factors; Treatment Outcome | 2012 |
Role of 5α-reductase inhibitors in prostate cancer prevention and treatment.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Azasteroids; Combined Modality Therapy; Drug Therapy, Combination; Dutasteride; Finasteride; Humans; Male; Primary Prevention; Prostatectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2012 |
[Chemoprevention of prostate cancer - a plea].
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anti-Inflammatory Agents, Non-Steroidal; Azasteroids; Cost Savings; Dutasteride; Finasteride; Germany; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; National Health Programs; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators | 2012 |
Future directions in cancer prevention.
Topics: Aromatase Inhibitors; Azasteroids; Breast Neoplasms; Cancer Vaccines; Diet; Dutasteride; Female; Finasteride; Humans; Immunotherapy; Life Style; Male; Motor Activity; Neoplasms; Nicotiana; Obesity; Prostatic Neoplasms; Selective Estrogen Receptor Modulators; Vaccines | 2012 |
Hormonal treatment for male-pattern hair loss: implications for cancer of the prostate?
Topics: Alopecia; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 2002 |
Prostate cancer epidemiology.
Topics: Adult; Aged; Diet; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors; Selenium | 2003 |
The clinical implications of the prostate cancer prevention trial.
Topics: Aged; Diagnostic Errors; Double-Blind Method; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
Prevention of prostate cancer with finasteride: US/European perspective.
Topics: Aged; Attitude of Health Personnel; Biopsy, Needle; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Europe; Finasteride; Humans; Immunohistochemistry; Male; Middle Aged; Practice Patterns, Physicians'; Primary Prevention; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Sensitivity and Specificity; Treatment Outcome; United States | 2003 |
Chemotherapeutic prevention studies of prostate cancer.
Topics: Anticarcinogenic Agents; Antioxidants; Azasteroids; Carotenoids; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Lycopene; Male; Prostatic Neoplasms; Vitamin E | 2004 |
The Prostate Cancer Prevention Trial: current status.
Topics: Anticarcinogenic Agents; Endpoint Determination; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Research Design | 2004 |
Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for prostate cancer.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Combined Modality Therapy; Diethylstilbestrol; Disease-Free Survival; Drug Administration Schedule; Enzyme Inhibitors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Male; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Salvage Therapy; Tosyl Compounds; Treatment Outcome | 2003 |
Effect of finasteride on risk of prostate cancer: how little we really know.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms; Testosterone | 2004 |
[Chemoprevention of prostate cancer].
Topics: Anticarcinogenic Agents; Azasteroids; Chemoprevention; Dutasteride; Europe; Finasteride; Humans; Male; Patient Care Management; Prostatic Neoplasms; Treatment Outcome | 2004 |
Update on chemoprevention of prostate cancer.
Topics: Aged; Carotenoids; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Lycopene; Male; Middle Aged; Prevalence; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selenium; Tea; United States; Vitamin D; Vitamin E | 2004 |
Finasteride, a selective 5-alpha-reductase inhibitor, in the prevention and treatment of human prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2004 |
Does finasteride alter the pathology of the prostate and cancer grading?
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Animals; Disease Models, Animal; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 2004 |
An update on the use of 5alpha-reductase inhibitors.
Topics: Adrenergic alpha-Antagonists; Azasteroids; Cholestenone 5 alpha-Reductase; Drug Therapy, Combination; Dutasteride; Finasteride; Humans; Isoenzymes; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2004 |
Prevention of hormone-related cancers: prostate cancer.
Topics: Androgens; Antineoplastic Agents, Hormonal; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Genetic Predisposition to Disease; Humans; Male; Models, Genetic; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors | 2005 |
Approach to management of clinically localized prostate cancer in patients with human immunodeficiency virus.
Topics: Adenocarcinoma; Adult; Aged; Anilides; Antineoplastic Agents, Hormonal; Antiretroviral Therapy, Highly Active; Biomarkers, Tumor; Brachytherapy; Case Management; Combined Modality Therapy; Cryosurgery; Finasteride; Follow-Up Studies; HIV Infections; Humans; Leuprolide; Life Expectancy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Radiotherapy, High-Energy; Retrospective Studies; Tosyl Compounds | 2005 |
[Prostate cancer. Introduction].
Topics: 5-alpha Reductase Inhibitors; alpha-Tocopherol; Antineoplastic Agents, Hormonal; Diet, Fat-Restricted; Diet, Vegetarian; Enzyme Inhibitors; Finasteride; Genetic Therapy; Humans; Male; Neoadjuvant Therapy; Prostatectomy; Prostatic Neoplasms; Radiotherapy; Selenium | 2005 |
[Risk factors and current chemoprevention studies in prostate cancer].
Topics: 5-alpha Reductase Inhibitors; beta Carotene; Dairy Products; Diet, Fat-Restricted; Diet, Vegetarian; Enzyme Inhibitors; Exercise; Finasteride; Fish Oils; Humans; Life Style; Male; Meat; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors; Selenium; Vitamin E | 2005 |
Implications of the prostate cancer prevention trial: a decision analysis model of survival outcomes.
Topics: Aged; Decision Trees; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome | 2005 |
The finasteride prostate cancer prevention trial (PCPT)--what have we learned?
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors | 2005 |
[Is tumour grade applicable to finasteride-treated prostate cancer?].
Topics: 5-alpha Reductase Inhibitors; Animals; Atrophy; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostate; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 2005 |
[Prevention of prostate cancer].
Topics: 5-alpha Reductase Inhibitors; Animals; Anticarcinogenic Agents; Azasteroids; Carotenoids; Dutasteride; Enzyme Inhibitors; Finasteride; Fishes; Flavonoids; Fruit; Humans; Isoflavones; Lycopene; Male; Neoplasms, Hormone-Dependent; Phenols; Polyphenols; Prostatic Neoplasms; Selenium; Soy Milk; Tea; Vegetables; Vitamin D; Vitamin E | 2005 |
Mechanisms of disease: Prostate cancer--a model for cancer chemoprevention in clinical practice.
Topics: Androgens; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemoprevention; Diet; Enzyme Inhibitors; Epidemiologic Studies; Finasteride; Humans; Inflammation; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2005 |
The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.
Topics: Antineoplastic Agents; Cholestenone 5 alpha-Reductase; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostatic Neoplasms | 2005 |
[Prostate cancer prevention].
Topics: Chemoprevention; Diet; Enzyme Inhibitors; Finasteride; Humans; Life Style; Male; Prostatic Neoplasms | 2006 |
Can prostate cancer be prevented?
Topics: Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Selenium; Vitamin E | 2005 |
Update on prostate cancer chemoprevention.
Topics: 5-alpha Reductase Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Azasteroids; Carotenoids; Chemoprevention; Clinical Trials as Topic; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Selenium; Vitamin E; Vitamins | 2006 |
[Prostate cancer chemoprevention].
Topics: Carotenoids; Drug Therapy; Enzyme Inhibitors; Finasteride; Humans; Isoflavones; Lycopene; Male; Prostatic Neoplasms; Selenium; Soy Foods; Vitamin A; Vitamin D; Vitamin E | 2005 |
Chemoprevention of prostate cancer with finasteride.
Topics: Animals; Antineoplastic Agents, Hormonal; Finasteride; Humans; Male; Prostatic Neoplasms | 2006 |
Finasteride as a chemopreventive agent in prostate cancer: impact of the PCPT on urologic practice.
Topics: Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Precancerous Conditions; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors; United States | 2006 |
Should finasteride be used to prevent prostate cancer?
Topics: Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2006 |
Looking back at PCPT: looking forward to new paradigms in prostate cancer screening and prevention.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors | 2007 |
Prostate cancer prevention and finasteride.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2006 |
A review of phase III clinical trials of prostate cancer chemoprevention.
Topics: Antineoplastic Agents; Azasteroids; Clinical Trials, Phase III as Topic; Dutasteride; Enzyme Inhibitors; Finasteride; Forecasting; Humans; Male; Prostatic Neoplasms; Selenium Compounds; Vitamin E | 2007 |
Hormonal interventions to prevent hormonal cancers: breast and prostate cancers.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Finasteride; Humans; Male; Primary Prevention; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen | 2007 |
Hormone ablation therapy: lightening the load for today's prostate cancer patient.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Drug Monitoring; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Mass Screening; Neoplasm Staging; Nurse's Role; Nursing Assessment; Oligopeptides; Patient Education as Topic; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quality of Life; Treatment Outcome | 2007 |
Chemoprevention of prostate cancer: lessons learned.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Family Practice; Finasteride; Humans; Male; Prostatic Neoplasms; Risk Factors; Risk Reduction Behavior | 2007 |
Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Azasteroids; Clinical Trials as Topic; Disease Progression; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Isoenzymes; Male; Prostatic Neoplasms | 2008 |
Role of 5 alpha-reductase inhibitors in the management of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Azasteroids; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2006 |
The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Receptor Antagonists; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Isoenzymes; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen | 2008 |
Five-alpha-reductase Inhibitors for prostate cancer prevention.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
Androgens and prevention of prostate cancer.
Topics: Androgens; Anticarcinogenic Agents; Azasteroids; Dutasteride; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms; Selenium; Signal Transduction; Vitamin E | 2008 |
The effect of finasteride on prostate specific antigen: review of available data.
Topics: 5-alpha Reductase Inhibitors; Adult; Age Factors; Aged; Aged, 80 and over; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Reference Values; Sensitivity and Specificity; Time Factors | 1996 |
Finasteride.
Topics: Acne Vulgaris; Alopecia; Androgens; Finasteride; Hirsutism; Humans; Male; Oxidoreductases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms | 1994 |
Prostate-specific antigen: critical issues for the practicing physician.
Topics: Adult; Age Distribution; Aged; Finasteride; Humans; Male; Middle Aged; Palpation; Prostate-Specific Antigen; Prostatic Neoplasms; Rectum; Reference Values | 1994 |
5 alpha-reductase inhibitors and prostatic disease.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgens; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Finasteride; Humans; Male; Prostate; Prostatic Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1994 |
Pathogenesis and medical management of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Androgen Antagonists; Finasteride; Humans; Male; Mass Screening; Middle Aged; Prostate-Specific Antigen; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms | 1994 |
Chemoprevention of prostate cancer.
Topics: Androgen Antagonists; Cholesterol; Depression, Chemical; Diet; Eflornithine; Finasteride; Humans; Male; Prostatic Neoplasms; Retinoids; Vitamin E | 1995 |
Chemoprevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 1995 |
Prostate cancer prevention: risk reduction through life-style, diet, and chemoprevention.
Topics: Diet; Finasteride; Humans; Life Style; Male; Prostatic Neoplasms; Risk Factors | 1994 |
The potential for hormonal prevention trials.
Topics: 5-alpha Reductase Inhibitors; Adult; Breast Neoplasms; Female; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen | 1994 |
Chemoprevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Dietary Fats; Eflornithine; Fenretinide; Finasteride; Humans; Male; Prevalence; Primary Prevention; Prostatic Neoplasms; Risk Factors | 1994 |
The potential application of finasteride for chemoprevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Animals; Anticarcinogenic Agents; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 1995 |
Finasteride: a clinical review.
Topics: Alopecia; Enzyme Inhibitors; Finasteride; Hirsutism; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 1995 |
Healthcare resources should be targeted to chemoprevention: the argument against.
Topics: Anticarcinogenic Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Enzyme Inhibitors; Erectile Dysfunction; Finasteride; Health Care Rationing; Health Resources; Humans; Male; Primary Prevention; Prostatic Neoplasms; Public Opinion | 1996 |
Screening for prostate cancer: opportunities for prevention.
Topics: Bias; Combined Modality Therapy; Enzyme Inhibitors; Finasteride; Humans; Male; Mass Screening; Primary Prevention; Prostatectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome | 1996 |
Evaluation of men on finasteride.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Mass Screening; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 1996 |
Selections from current literature: androgenetic alopecia: the science behind a new oral treatment.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Biomarkers, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 1998 |
Prostatic adenocarcinoma following androgen deprivation therapy: the new difficulty in histologic interpretation.
Topics: Adenocarcinoma; Androgen Antagonists; Cholestenone 5 alpha-Reductase; Diagnosis, Differential; Enzyme Inhibitors; Finasteride; Humans; Immunohistochemistry; Male; Oxidoreductases; Prostatic Neoplasms | 1998 |
Hormonal manipulation for rising PSA after radical prostatectomy.
Topics: Androgen Antagonists; Anilides; Drug Therapy, Combination; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Male; Neoplasm Recurrence, Local; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Tosyl Compounds | 1999 |
Treatment changes in prostatic hyperplasia and cancer, including androgen deprivation therapy and radiotherapy.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Enzyme Inhibitors; Finasteride; Humans; Immunohistochemistry; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 1999 |
Prostate cancer prevention trials in the USA.
Topics: 5-alpha Reductase Inhibitors; Aged; Animals; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Rabbits; Risk Factors; Selenium; Vitamin E | 2000 |
Exploitable mechanisms for the blockade of androgenic action.
Topics: Androgen Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Estrogens; Finasteride; Forecasting; Humans; Intracellular Membranes; Male; Prostatic Neoplasms; Protein-Tyrosine Kinases; Signal Transduction | 2000 |
Pharmacogenetics of human androgens and prostatic diseases.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Finasteride; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Male; Pharmacogenetics; Polymorphism, Single Nucleotide; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen | 2001 |
Androgen deprivation therapy for patients with clinically localized (stages T1 to T3) prostate cancer and for patients with biochemical recurrence after radical prostatectomy.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Clinical Trials as Topic; Disease Progression; Drug Administration Schedule; Finasteride; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Orchiectomy; Postoperative Complications; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quality of Life; Treatment Outcome | 2001 |
Androgen deprivation therapy for prostate cancer chemoprevention: current status and future directions for agent development.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Chemoprevention; Drug Design; Finasteride; Gene Expression Profiling; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 2001 |
Prevention of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgen Antagonists; Androgens; Animals; Anticarcinogenic Agents; Antioxidants; Carotenoids; Case-Control Studies; Cohort Studies; Dietary Fats; Double-Blind Method; Enzyme Inhibitors; Finasteride; Genetic Predisposition to Disease; Humans; Incidence; Insulin-Like Growth Factor I; Life Style; Lycopene; Male; Mice; Mice, Transgenic; Micronutrients; Neoplasms, Hormone-Dependent; Prospective Studies; Prostatic Hyperplasia; Prostatic Neoplasms; Racial Groups; Randomized Controlled Trials as Topic; Risk Factors; Selenium; Soybean Proteins; Vitamin D; Vitamin E | 2001 |
5alpha-reductase activity in the prostate.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Cryptorchidism; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Forecasting; Humans; Infertility, Male; Isoenzymes; Male; Mice; Mice, Knockout; Mutation; Penile Erection; Penis; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Testis; Tumor Cells, Cultured | 2001 |
The future of prostate cancer prevention.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Adult; Aged; Androgen Antagonists; Androgens; Anticarcinogenic Agents; Antioxidants; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diet; Double-Blind Method; Enzyme Inhibitors; Finasteride; Forecasting; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk; Selenium; Soybean Proteins; Treatment Outcome; Vitamin A; Vitamin D; Vitamin E | 2001 |
Chemoprevention strategies for prostate cancer: the role of 5 alpha-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Aged; Androgens; Androstenes; Animals; Azasteroids; Finasteride; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms | 1992 |
Chemoprevention of prostate cancer: guidelines for possible intervention strategies.
Topics: Androstenes; Anticarcinogenic Agents; Azasteroids; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 1992 |
Dual control by androgens and peptide growth factors of prostatic growth in human benign prostatic hyperplasia.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenes; Azasteroids; Carcinoma; Cell Division; Cells, Cultured; Dihydrotestosterone; Epidermal Growth Factor; Finasteride; Gonadotropin-Releasing Hormone; Growth Substances; Humans; Insulin-Like Growth Factor I; Male; Peptides; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Tumor Cells, Cultured | 1991 |
Role of 5 alpha-reductase inhibitors in the treatment of advanced prostatic carcinoma.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenes; Animals; Azasteroids; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms | 1991 |
89 trial(s) available for finasteride and Cancer of Prostate
Article | Year |
---|---|
Serum markers, obesity and prostate cancer risk: results from the prostate cancer prevention trial.
Topics: Biomarkers; Case-Control Studies; Finasteride; Humans; Male; Obesity; Prostatic Neoplasms; Risk Factors | 2022 |
Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT.
Topics: 5-alpha Reductase Inhibitors; Aged; Biomarkers, Tumor; Case-Control Studies; Clinical Trials as Topic; DNA Mutational Analysis; Finasteride; Follow-Up Studies; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Male; Polymorphism, Single Nucleotide; Prognosis; Prostatic Neoplasms; Risk Factors; Survival Rate | 2020 |
Comparative Healthcare Research Outcomes of Novel Surgery in prostate cancer (IP4-CHRONOS): A prospective, multi-centre therapeutic phase II parallel Randomised Control Trial.
Topics: Ablation Techniques; Androgen Antagonists; Anilides; Brachytherapy; Costs and Cost Analysis; Equivalence Trials as Topic; Finasteride; Humans; Male; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Progression-Free Survival; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Radiotherapy; Research Design; Tosyl Compounds; United Kingdom | 2020 |
Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial.
Topics: Aged; Biopsy; Finasteride; Genetic Association Studies; Humans; Inflammation; Interleukin-10; Interleukin-8; Male; Middle Aged; Neoplasm Grading; Polymorphism, Single Nucleotide; Prostate; Prostatic Neoplasms; Urological Agents | 2017 |
Hormonal manipulation with finasteride or oral contraception does not influence incidence of renal cell carcinoma.
Topics: 5-alpha Reductase Inhibitors; Aged; Carcinoma, Renal Cell; Colorectal Neoplasms; Contraception; Contraceptives, Oral; Dutasteride; Female; Finasteride; Follow-Up Studies; Humans; Incidence; Kidney Neoplasms; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors; Self Report | 2018 |
Prognostic value of urinary prostate cancer antigen 3 (PCA3) during active surveillance of patients with low-risk prostate cancer receiving 5α-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Aged; Antigens, Neoplasm; Dutasteride; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Grading; Prospective Studies; Prostatic Neoplasms; Risk Factors; Single-Blind Method; Watchful Waiting | 2018 |
Associations between polymorphisms in genes related to estrogen metabolism and function and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Aromatase; Case-Control Studies; Estrogens; Finasteride; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms | 2018 |
Circadian genes and risk of prostate cancer in the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Circadian Clocks; Finasteride; Humans; Male; Middle Aged; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Prostate; Prostatic Neoplasms; Risk Factors | 2018 |
Finasteride does not prevent bladder cancer: A secondary analysis of the Medical Therapy for Prostatic Symptoms Study.
Topics: 5-alpha Reductase Inhibitors; Androgens; Dihydrotestosterone; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Urinary Bladder Neoplasms | 2018 |
The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Biopsy; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Oncogene Proteins, Fusion; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 2018 |
Case-only Methods Identified Genetic Loci Predicting a Subgroup of Men with Reduced Risk of High-grade Prostate Cancer by Finasteride.
Topics: 5-alpha Reductase Inhibitors; Biomarkers, Tumor; Finasteride; Genetic Loci; Humans; Male; Middle Aged; Neoplasm Grading; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Factors | 2019 |
Effect of finasteride on serum levels of androstenedione, testosterone and their 5α-reduced metabolites in men at risk for prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Androstenedione; Dihydrotestosterone; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 2013 |
Predicting risk of prostate cancer in men receiving finasteride: effect of prostate volume, number of biopsy cores, and American Urological Association symptom score.
Topics: Aged; Aged, 80 and over; Anticarcinogenic Agents; Biopsy; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Regression Analysis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Urological Agents | 2013 |
Factors associated with adherence to an end-of-study biopsy: lessons from the prostate cancer prevention trial (SWOG-Coordinated Intergroup Study S9217).
Topics: 5-alpha Reductase Inhibitors; Biopsy; Double-Blind Method; Finasteride; Humans; Male; Patient Compliance; Prostatic Neoplasms; Research Design; ROC Curve | 2014 |
Serum 25-hydroxyvitamin D concentrations and risk of prostate cancer: results from the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Case-Control Studies; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Vitamin D | 2014 |
Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease.
Topics: Androstenedione; Case-Control Studies; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms; Risk Assessment | 2015 |
Treatment satisfaction and clinically meaningful symptom improvement in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: Secondary results from a 6-month, randomized, double-blind study comparing f
Topics: 5-alpha Reductase Inhibitors; Aged; Double-Blind Method; Drug Therapy, Combination; Finasteride; Humans; Male; Middle Aged; Organ Size; Patient Satisfaction; Phosphodiesterase 5 Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatism; Severity of Illness Index; Tadalafil | 2015 |
Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Chromosomal Instability; Disease Progression; Finasteride; Humans; Male; Middle Aged; Prostate; Prostatic Neoplasms; Risk Factors; Stromal Cells; Telomere Homeostasis; Telomere Shortening | 2015 |
Finasteride concentrations and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
Topics: Aged; Case-Control Studies; Cytochrome P-450 CYP3A; Finasteride; Genetic Testing; Humans; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms | 2015 |
Serum Retinol and Carotenoid Concentrations and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Antioxidants; Biomarkers, Tumor; Carotenoids; Finasteride; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Pilot Projects; Prospective Studies; Prostatic Neoplasms; Risk Factors; Survival Rate; Time Factors; United States; Vitamin A; Vitamins | 2015 |
Non-steroidal anti-inflammatory drug (NSAID) use is not associated with erectile dysfunction risk: results from the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Erectile Dysfunction; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors | 2016 |
Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer.
Topics: Administration, Oral; Aged; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Double-Blind Method; Finasteride; Humans; Logistic Models; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms; Receptors, Androgen; Treatment Outcome | 2016 |
The Prostate Cancer Prevention Trial and European Randomized Study of Screening for Prostate Cancer risk calculators indicating a positive prostate biopsy: a comparison.
Topics: Aged; Biopsy, Needle; Finasteride; Humans; Male; Mass Screening; Middle Aged; Multivariate Analysis; Nomograms; Predictive Value of Tests; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors | 2008 |
Serum steroid and sex hormone-binding globulin concentrations and the risk of incident benign prostatic hyperplasia: results from the prostate cancer prevention trial.
Topics: Aged; Finasteride; Follow-Up Studies; Gonadal Steroid Hormones; Humans; Incidence; Male; Middle Aged; Prevalence; Prognosis; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies; Sex Hormone-Binding Globulin; Surveys and Questionnaires; Time Factors; United States | 2008 |
Effects of short-term finasteride on apoptotic factors and androgen receptors in prostate cancer cells.
Topics: Aged; Apoptosis; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Schedule; Finasteride; Humans; Immunohistochemistry; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Probability; Prognosis; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Receptors, Androgen; Reference Values; Sensitivity and Specificity; Tumor Cells, Cultured | 2009 |
Pathologic characteristics of cancers detected in The Prostate Cancer Prevention Trial: implications for prostate cancer detection and chemoprevention.
Topics: Aged; Antineoplastic Agents; Biopsy; Chemoprevention; Early Detection of Cancer; Finasteride; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Organ Size; Placebos; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Treatment Outcome; Tumor Burden | 2008 |
Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach.
Topics: Aged; Bias; Biomarkers; Biopsy; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Models, Statistical; Neoplasm Staging; Odds Ratio; Placebos; Prevalence; Prostatectomy; Prostatic Neoplasms; Risk | 2008 |
Estimating rates of true high-grade disease in the prostate cancer prevention trial.
Topics: Aged; Antineoplastic Agents; Biopsy; Disease Progression; False Positive Reactions; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Placebos; Prostatic Neoplasms | 2008 |
Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up.
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Epidemiologic Methods; Finasteride; Flutamide; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 2009 |
PCPT: Evidence that finasteride reduces risk of most frequently detected intermediate- and high-grade (Gleason score 6 and 7) cancer.
Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Age Factors; Aged; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Detection of Cancer; Finasteride; Humans; Immunohistochemistry; Logistic Models; Male; Middle Aged; Neoplasm Staging; Primary Prevention; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Treatment Outcome; Tumor Burden | 2009 |
Finasteride modifies the relation between serum C-peptide and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
Topics: C-Peptide; Case-Control Studies; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Finasteride; Humans; Insulin Resistance; Leptin; Male; Middle Aged; Prostatic Neoplasms; Risk Factors | 2010 |
Serum oxidized protein and prostate cancer risk within the Prostate Cancer Prevention Trial.
Topics: Case-Control Studies; Double-Blind Method; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Finasteride; Humans; Male; Middle Aged; Oxidative Stress; Prostatic Neoplasms; Protein Carbonylation; Risk Factors | 2010 |
Serum lycopene concentration and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Biomarkers, Tumor; Carotenoids; Case-Control Studies; Finasteride; Humans; Lycopene; Male; Middle Aged; Prostatic Neoplasms; Risk Factors | 2011 |
Serum phospholipid fatty acids and prostate cancer risk: results from the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Finasteride; Humans; Male; Middle Aged; Prevalence; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors | 2011 |
Association of symptomatic benign prostatic hyperplasia and prostate cancer: results from the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Finasteride; Humans; Male; Middle Aged; Prevalence; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors | 2011 |
A randomized phase IIb presurgical study of finasteride vs. low-dose flutamide vs. placebo in men with prostate cancer. Efficacy monitored by karyometry.
Topics: 5-alpha Reductase Inhibitors; Aged; Androgen Antagonists; Cell Nucleus; Cost-Benefit Analysis; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Finasteride; Flutamide; Humans; Karyometry; Male; Middle Aged; Preoperative Period; Prospective Studies; Prostate; Prostatic Neoplasms; Treatment Outcome | 2013 |
Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Failure | 2012 |
Prospective study of cytomegalovirus serostatus and prostate cancer risk in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Cytomegalovirus; Cytomegalovirus Infections; Finasteride; Humans; Male; Middle Aged; Prospective Studies; Prostatic Neoplasms; Risk Factors; Seroepidemiologic Studies | 2012 |
Associations of serum sex steroid hormone and 5α-androstane-3α,17β-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride.
Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Case-Control Studies; Finasteride; Glucuronides; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk; Sex Hormone-Binding Globulin | 2012 |
Health-related quality-of-life findings for the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Activities of Daily Living; Aged; Anticarcinogenic Agents; Finasteride; Health Status; Humans; Male; Mental Health; Middle Aged; Models, Statistical; Prospective Studies; Prostatic Neoplasms; Quality of Life; Surveys and Questionnaires | 2012 |
Insulin-like growth factors and insulin-like growth factor-binding proteins and prostate cancer risk: results from the prostate cancer prevention trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Case-Control Studies; Finasteride; Humans; Insulin-Like Growth Factor Binding Proteins; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Somatomedins | 2013 |
PSA response to finasteride challenge in men with a serum PSA greater than 4 ng/ml and previous negative prostate biopsy: preliminary study.
Topics: Biopsy, Needle; Depression, Chemical; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Palpation; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 2002 |
Biomarker-based methods for determining noncompliance in a prevention trial.
Topics: Aged; Algorithms; Biomarkers; Dihydrotestosterone; Drug Monitoring; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Patient Compliance; Prostatic Neoplasms; Randomized Controlled Trials as Topic; ROC Curve; Sensitivity and Specificity | 2002 |
The influence of finasteride on the development of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Antineoplastic Agents, Hormonal; Biopsy; Finasteride; Humans; Male; Middle Aged; Morbidity; Neoplasms, Hormone-Dependent; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 2003 |
Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up.
Topics: Adenocarcinoma; Adult; Aged; Androgen Antagonists; Androgens; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Enzyme Inhibitors; Finasteride; Flutamide; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Salvage Therapy; Survival Rate; Treatment Outcome | 2003 |
Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Enzyme Inhibitors; Finasteride; Flutamide; Follow-Up Studies; Humans; Life Tables; Male; Neoplasm Recurrence, Local; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Radioisotope Teletherapy; Survival Analysis; Treatment Outcome | 2003 |
Implementation of the Prostate Cancer Prevention Trial (PCPT).
Topics: Chemoprevention; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prevalence; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Research Design | 2004 |
Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biopsy; Finasteride; Humans; Male; Middle Aged; Prevalence; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Risk | 2004 |
Combined modality treatment in the management of high-risk prostate cancer.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Brachytherapy; Combined Modality Therapy; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Palladium; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiotherapy, Conformal; Testosterone | 2004 |
Effect of short-term finasteride therapy on peroperative bleeding in patients who were candidates for transurethral resection of the prostate (TUR-P): a randomized controlled study.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Finasteride; Hemoglobins; Humans; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Renal Insufficiency; Risk; Time Factors; Transurethral Resection of Prostate; Urethra; Warfarin | 2005 |
Long-term effects of finasteride on prostate specific antigen levels: results from the prostate cancer prevention trial.
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Double-Blind Method; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Long-Term Care; Male; Middle Aged; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Reference Values | 2005 |
Effect of finasteride on the sensitivity of PSA for detecting prostate cancer.
Topics: Aged; Area Under Curve; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Research Design; ROC Curve; Sensitivity and Specificity | 2006 |
Obesity, diabetes, and risk of prostate cancer: results from the prostate cancer prevention trial.
Topics: Adenocarcinoma; Age Factors; Aged; Body Mass Index; Diabetes Mellitus; Enzyme Inhibitors; Finasteride; Humans; Logistic Models; Male; Middle Aged; Neoplasm Staging; Obesity; Prostatic Neoplasms; Research Design; Risk Factors; Waist-Hip Ratio | 2006 |
Sensitivity and specificity of prostate-specific antigen for prostate cancer detection with high rates of biopsy verification.
Topics: Biopsy; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Sensitivity and Specificity | 2006 |
Finasteride improves the sensitivity of digital rectal examination for prostate cancer detection.
Topics: Biopsy; Diagnosis, Differential; Digital Rectal Examination; Dose-Response Relationship, Drug; Enzyme Inhibitors; Finasteride; Humans; Male; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Sensitivity and Specificity | 2007 |
Finasteride decreases the risk of prostatic intraepithelial neoplasia.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 2007 |
Longitudinal analysis of sexual function reported by men in the Prostate Cancer Prevention Trial.
Topics: Aged; Anticarcinogenic Agents; Cholestenone 5 alpha-Reductase; Double-Blind Method; Enzyme Inhibitors; Erectile Dysfunction; Finasteride; Humans; Longitudinal Studies; Male; Middle Aged; Placebos; Prostatic Neoplasms; Surveys and Questionnaires; Time Factors | 2007 |
Prediction of prostate cancer for patients receiving finasteride: results from the Prostate Cancer Prevention Trial.
Topics: Administration, Oral; Aged; Biopsy, Needle; Confidence Intervals; Digital Rectal Examination; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Finasteride; Follow-Up Studies; Humans; Immunohistochemistry; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Predictive Value of Tests; Preventive Medicine; Probability; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome | 2007 |
Detection bias due to the effect of finasteride on prostate volume: a modeling approach for analysis of the Prostate Cancer Prevention Trial.
Topics: Aged; Anticarcinogenic Agents; Bias; Biopsy, Needle; Enzyme Inhibitors; Finasteride; Humans; Incidence; Logistic Models; Male; Middle Aged; Models, Statistical; Odds Ratio; Prostatic Neoplasms; Rectum; Research Design; Severity of Illness Index; Treatment Outcome; Ultrasonography; United States | 2007 |
Finasteride and high-grade prostate cancer in the Prostate Cancer Prevention Trial.
Topics: Aged; Anticarcinogenic Agents; Bias; Biopsy, Needle; Black or African American; Confounding Factors, Epidemiologic; Enzyme Inhibitors; Finasteride; Humans; Incidence; Logistic Models; Male; Middle Aged; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Severity of Illness Index; United States; White People | 2007 |
Finasteride, prostate cancer, and weight gain: evidence for genetic or environmental factors that affect cancer outcomes during finasteride treatment.
Topics: Aged; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Linear Models; Male; Middle Aged; Prostatic Neoplasms; Treatment Outcome; Weight Gain | 2008 |
Effect of finasteride on prostate-specific antigen density.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Finasteride; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Predictive Value of Tests; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Sensitivity and Specificity | 1994 |
Three-year safety and efficacy data on the use of finasteride in the treatment of benign prostatic hyperplasia.
Topics: Adult; Aged; Aged, 80 and over; Dihydrotestosterone; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Severity of Illness Index; Urodynamics | 1994 |
Clinical experience of the detection of prostate cancer in patients with benign prostate hyperplasia treated with finasteride. The Finasteride Study Group.
Topics: Aged; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Palpation; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 1994 |
Treatment with finasteride following radical prostatectomy for prostate cancer.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms | 1995 |
Design of the Prostate Cancer Prevention Trial (PCPT).
Topics: Aged; Bias; Confounding Factors, Epidemiologic; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Random Allocation; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Sample Size; Sexual Dysfunction, Physiological; United States | 1995 |
Combination finasteride and flutamide in advanced carcinoma of the prostate: effective therapy with minimal side effects.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Enzyme Inhibitors; Finasteride; Flutamide; Follow-Up Studies; Humans; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Testosterone | 1995 |
Prostate Cancer Prevention Trial launched.
Topics: Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms | 1993 |
Combined finasteride and flutamide therapy in men with advanced prostate cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Male; Middle Aged; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms | 1996 |
Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate.
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Enzyme Inhibitors; Erectile Dysfunction; Finasteride; Flutamide; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Sexuality; Treatment Failure | 1997 |
Biologic variability of prostate-specific antigen and its usefulness as a marker for prostate cancer: effects of finasteride. The Finasteride PSA Study Group.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 1997 |
The chemoprevention of prostate cancer and the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Androgens; Antineoplastic Agents; Chemoprevention; Combined Modality Therapy; Disease Progression; Eflornithine; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Vitamins | 1996 |
Chemoprevention of prostate cancer: the Prostate Cancer Prevention Trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Selenium; Vitamin D; Vitamin E | 1997 |
Army and Air Force leadership in the Prostate Cancer Prevention Trial.
Topics: Enzyme Inhibitors; Finasteride; Humans; Leadership; Male; Middle Aged; Military Personnel; Prostatic Neoplasms; United States | 1998 |
Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: results of a randomized, double-blind, placebo-controlled clinical trial. PLESS Study Group. Proscar Long-term Efficacy and Safety Study.
Topics: Aged; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Sensitivity and Specificity | 1998 |
The effect of finasteride on the prostate gland in men with elevated serum prostate-specific antigen levels.
Topics: Adenocarcinoma; Aged; Biopsy; Cell Division; Enzyme Inhibitors; Epithelial Cells; Evaluation Studies as Topic; Finasteride; Humans; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 1998 |
Biochemical response to testicular androgen ablation among patients with prostate cancer for whom flutamide and/or finasteride therapy failed.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Failure | 1998 |
Does long-term finasteride therapy affect the histologic features of benign prostatic tissue and prostate cancer on needle biopsy? PLESS Study Group. Proscar Long-Term Efficacy and Safety Study.
Topics: Aged; Biopsy, Needle; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Time Factors | 1999 |
Prostate Cancer Prevention Trial (PCPT) update.
Topics: Aged; Biopsy, Needle; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Libido; Male; Middle Aged; Prostatic Neoplasms; Survival Rate; Treatment Outcome; United States | 1999 |
Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland. International Prostate Health Council (IPHC) Trial Study Group.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Follicle Stimulating Hormone; Goserelin; Humans; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms | 1999 |
Serum prostate-specific antigen and prostate volume predict long-term changes in symptoms and flow rate: results of a four-year, randomized trial comparing finasteride versus placebo. PLESS Study Group.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Urodynamics | 1999 |
Intermittent androgen suppression for prostate cancer: Canadian Prospective Trial and related observations.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cyclic AMP-Dependent Protein Kinases; Disease Progression; Enzyme Inhibitors; Finasteride; Humans; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Receptors, Androgen; Signal Transduction; Testosterone; Time Factors; Tosyl Compounds | 2000 |
Minority recruitment in the prostate cancer prevention trial.
Topics: Aged; Demography; Finasteride; Humans; Life Style; Male; Middle Aged; Minority Groups; Patient Selection; Pilot Projects; Placebos; Prostatic Neoplasms; Racial Groups; Randomized Controlled Trials as Topic | 2000 |
The Prostate Cancer Prevention Trial: Current status and lessons learned.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Palpation; Patient Selection; Prostate-Specific Antigen; Prostatic Neoplasms | 2001 |
Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Follow-Up Studies; Gonadotropin-Releasing Hormone; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoplasm Staging; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds; Treatment Outcome | 2001 |
Dietary supplement use in the Prostate Cancer Prevention Trial: implications for prevention trials.
Topics: Aged; Antioxidants; Body Mass Index; Dietary Supplements; Double-Blind Method; Educational Status; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Primary Prevention; Prostatic Neoplasms; Risk Factors; Surveys and Questionnaires; Time Factors | 2001 |
Docetaxel followed by hormone therapy after failure of definitive treatments for clinically localized/locally advanced prostate cancer: preliminary results.
Topics: Adenocarcinoma; Aged; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Docetaxel; Finasteride; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Paclitaxel; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Salvage Therapy; Taxoids; Tosyl Compounds | 2001 |
Castration-like effects on the human prostate of a 5 alpha-reductase inhibitor, finasteride.
Topics: 5-alpha Reductase Inhibitors; Androstenes; Azasteroids; Dihydrotestosterone; Finasteride; Humans; Male; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1992 |
Multicenter, randomized, double-blind, placebo controlled study to investigate the effect of finasteride (MK-906) on stage D prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Acid Phosphatase; Aged; Aged, 80 and over; Androstenes; Azasteroids; Biomarkers, Tumor; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life | 1992 |
285 other study(ies) available for finasteride and Cancer of Prostate
Article | Year |
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19-nor-10-azasteroids: a novel class of inhibitors for human steroid 5alpha-reductases 1 and 2.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Enzyme Inhibitors; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Prostatic Neoplasms; Tumor Cells, Cultured | 1997 |
Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Microsomes; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis; Triazoles; Tumor Cells, Cultured | 1998 |
A novel class of inhibitors for steroid 5alpha-reductase: synthesis and evaluation of umbelliferone derivatives.
Topics: 5-alpha Reductase Inhibitors; Coumarins; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Male; Prostatic Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured; Umbelliferones | 2001 |
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Azoles; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Humans; Isoenzymes; Male; Mice; Mice, SCID; Mutation; Prostatic Neoplasms; Pyrazines; Radioligand Assay; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Tissue Distribution; Transcription, Genetic; Transcriptional Activation; Xenograft Model Antitumor Assays | 2005 |
In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; 5-alpha Reductase Inhibitors; Animals; Bile; Drug Interactions; Finasteride; Half-Life; Injections, Intravenous; Intestinal Absorption; Ketoconazole; Liver; Male; Prostatic Neoplasms; Swine | 2011 |
Effect of dehydroepiandrosterone derivatives on the activity of 5α-reductase isoenzymes and on cancer cell line PC-3.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Cholestenone 5 alpha-Reductase; Cricetinae; Dehydroepiandrosterone; Female; Humans; Isoenzymes; Male; Mice; Middle Aged; Prostate; Prostatic Neoplasms; Rats | 2014 |
Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line.
Topics: Androgens; Androstenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Humans; Leukocytes, Mononuclear; Male; Prostatic Neoplasms; Rats | 2016 |
Synthesis and biological evaluation of arylpiperazine derivatives as potential anti-prostate cancer agents.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Male; Molecular Docking Simulation; Molecular Structure; Piperazines; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship | 2019 |
Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fluorescence Polarization; Humans; Male; Molecular Docking Simulation; Molecular Structure; Piperazine; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
A prospective evaluation of the effect of finasteride on prostate health index (phi).
Topics: Finasteride; Humans; Male; Prospective Studies; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 2023 |
5α-Reductase Inhibitor Use in Patients With Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Oxidoreductases; Prostatic Neoplasms | 2019 |
5α-Reductase Inhibitor Use in Patients With Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Oxidoreductases; Prostatic Neoplasms | 2019 |
5α-Reductase Inhibitor Use in Patients With Prostate Cancer-Reply.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Oxidoreductases; Prostatic Neoplasms | 2019 |
Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androstenes; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biopsy; Cell Nucleus; Cohort Studies; ErbB Receptors; Estrogen Receptor beta; Finasteride; Humans; Male; Mice; Mice, Knockout; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Phytoestrogens; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; PTEN Phosphohydrolase; Receptors, Androgen; Receptors, Estrogen | 2021 |
Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition.
Topics: 5-alpha Reductase Inhibitors; Aged; Animals; Biomarkers, Tumor; Chemotherapy, Adjuvant; Clinical Decision-Making; DNA Mutational Analysis; Dutasteride; Finasteride; Homeodomain Proteins; Humans; Male; Mice, Knockout; Middle Aged; Mutation; Neoadjuvant Therapy; Neoplasm Staging; Patient Selection; Precision Medicine; Predictive Value of Tests; Prostatectomy; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Retrospective Studies; Time Factors; Transcription Factors; Treatment Outcome | 2017 |
Re: Long-Term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial.
Topics: Finasteride; Humans; Male; Prostatic Neoplasms | 2018 |
Imaging prostate cancer (PCa) with [
Topics: Animals; Finasteride; Male; Molecular Imaging; Organotechnetium Compounds; Prostatic Neoplasms; Rats; Tissue Distribution | 2018 |
Using Medicare Claims to Examine Long-term Prostate Cancer Risk of Finasteride in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Biopsy; Case-Control Studies; Finasteride; Follow-Up Studies; Humans; Incidence; Male; Medicare; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Public Health Surveillance; United States | 2018 |
Finasteride-Nemesis of More Than 1 Urological Cancer?
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Oxidoreductases; Prostatic Hyperplasia; Prostatic Neoplasms; Urinary Bladder Neoplasms | 2018 |
Re: Using Medicare Claims to Examine Long-Term Prostate Cancer Risk of Finasteride in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Medicare; Prostatic Neoplasms; United States | 2018 |
Long-Term Effects of Finasteride on Prostate Cancer Mortality.
Topics: 5-alpha Reductase Inhibitors; Early Detection of Cancer; Finasteride; Humans; Male; Middle Aged; Neoplasm Grading; Prostate-Specific Antigen; Prostatic Neoplasms | 2019 |
More on Long-Term Effects of Finasteride on Prostate Cancer Mortality.
Topics: Finasteride; Humans; Male; Prostatic Neoplasms | 2019 |
More on Long-Term Effects of Finasteride on Prostate Cancer Mortality.
Topics: Finasteride; Humans; Male; Prostatic Neoplasms | 2019 |
More on Long-Term Effects of Finasteride on Prostate Cancer Mortality. Reply.
Topics: Finasteride; Humans; Male; Prostatic Neoplasms | 2019 |
5-alpha reductase inhibitors in patients on active surveillance: do the benefits outweigh the risk?
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Disease Progression; Dutasteride; Finasteride; Humans; Kallikreins; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Watchful Waiting | 2013 |
Actos, slings, finasteride, and the vaccine compensation solution.
Topics: Finasteride; Humans; Liability, Legal; Male; Patient Rights; Pioglitazone; Prostatic Neoplasms; Risk Assessment; Risk Factors; Suburethral Slings; Thiazolidinediones; United States; United States Food and Drug Administration; Urinary Bladder Neoplasms; Vaccines | 2013 |
5α-reductase inhibition suppresses testosterone-induced initial regrowth of regressed xenograft prostate tumors in animal models.
Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Cell Line, Tumor; Cell Proliferation; Dutasteride; Finasteride; Humans; Immunohistochemistry; Letrozole; Male; Mice; Mice, Nude; Mice, SCID; Nitriles; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Triazoles | 2013 |
Rank-based principal stratum sensitivity analyses.
Topics: AIDS Vaccines; Computer Simulation; Data Interpretation, Statistical; Finasteride; HIV Infections; Humans; Male; Prostatic Neoplasms; Treatment Outcome | 2013 |
Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Cell Line, Tumor; Dihydrotestosterone; Dutasteride; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tandem Mass Spectrometry; Testosterone | 2013 |
The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific.
Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Cattle; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dutasteride; Finasteride; Gene Expression Regulation; Humans; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Transfection | 2013 |
Re: effect of finasteride on serum levels of androstenedione, testosterone and their 5α-reduced metabolites in men at risk for prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androstenedione; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2013 |
Response to commentary.
Topics: 5-alpha Reductase Inhibitors; Androstenedione; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2013 |
Long-term survival of participants in the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Neoplasm Grading; Prostatic Neoplasms; Risk; Survival Rate | 2013 |
A role for finasteride in the prevention of prostate cancer?
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2013 |
Finasteride for prostate cancer prevention has no effect on survival, study finds.
Topics: 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Disease-Free Survival; Finasteride; Humans; Male; Prostatic Neoplasms; United States | 2013 |
Urological cancer: reduction in the risk of prostate cancer with finasteride.
Topics: Finasteride; Humans; Male; Prognosis; Prostatic Neoplasms; Risk Factors; Urologic Neoplasms; Urological Agents | 2013 |
Prostate cancer: mortality unaffected by finasteride treatment.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2013 |
Editorial comment.
Topics: Biopsy; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms | 2013 |
Preventive and therapeutic efficacy of finasteride and dutasteride in TRAMP mice.
Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Body Weight; Cholestenone 5 alpha-Reductase; Disease Progression; Dutasteride; Finasteride; Lymph Nodes; Lymphatic Metastasis; Male; Mice; Mice, Inbred C57BL; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor, Member 25 | 2013 |
Survival in the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2013 |
Survival in the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2013 |
Survival in the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2013 |
Are 5-ARIs suitable for prevention of prostate cancer?
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; United Kingdom | 2013 |
Finasteride inhibits human prostate cancer cell invasion through MMP2 and MMP9 downregulation.
Topics: 5-alpha Reductase Inhibitors; Cell Line, Tumor; Cell Survival; Down-Regulation; Finasteride; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepatitis A Virus Cellular Receptor 1; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Glycoproteins; Neoplasm Invasiveness; Neoplasm Proteins; Prostatic Neoplasms; Receptors, Virus; Tissue Inhibitor of Metalloproteinase-2 | 2013 |
Re: long-term survival of participants in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2014 |
Re: long-term survival of participants in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2014 |
Re: long-term survival of participants in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2014 |
Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer.
Topics: Adult; Alopecia; Androgens; Cell Proliferation; Dihydrotestosterone; Finasteride; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Models, Theoretical; Prostaglandin D2; Prostatic Neoplasms | 2014 |
Finasteride reduces cancer risk, does not increase death risk.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Mortality; Prostatic Neoplasms | 2013 |
Re: predicting risk of prostate cancer in men receiving finasteride: effect of prostate volume, number of biopsy cores, and american urological association symptom score.
Topics: Biopsy; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms | 2014 |
[Prevention of prostate cancer. Long-term results of the Prostate Cancer Prevention Trial (PCPT)].
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2014 |
Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenedione; Azasteroids; Chromatography, Liquid; Dihydrotestosterone; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Solid Phase Extraction; Tandem Mass Spectrometry; Testosterone; Tissue Distribution | 2015 |
Prostatic angiogenic responses in late life: antiangiogenic therapy influences and relation with the glandular microenvironment in the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Angiogenesis Inhibitors; Animals; Blotting, Western; Cyclohexanes; Disease Models, Animal; Endostatins; Fibroblast Growth Factor 2; Finasteride; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indoles; Male; Mice; Mice, Transgenic; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Prostatic Neoplasms; Pyrroles; Sesquiterpenes; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2015 |
5α-Reductase Inhibitors and the Risk of Cancer-Related Mortality in Men With Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Databases, Factual; Dutasteride; Finasteride; Humans; Incidence; Kaplan-Meier Estimate; Linear Models; Logistic Models; Male; Multivariate Analysis; Propensity Score; Proportional Hazards Models; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United Kingdom | 2015 |
Effect of 5α-Reductase Inhibitor Use on Mortality From Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2015 |
Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.
Topics: Age Factors; Aging; Angiogenesis Inhibitors; Animals; Finasteride; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Prostate; Prostatic Neoplasms; Stromal Cells | 2015 |
Finasteride and Bladder Cancer.
Topics: Enzyme Inhibitors; Finasteride; Humans; Prostatic Hyperplasia; Prostatic Neoplasms; Urinary Bladder Neoplasms | 2016 |
Expression of Heat Shock Protein 27 in Benign Prostatic Hyperplasia with Chronic Inflammation.
Topics: Adrenergic alpha-Antagonists; Biomarkers, Tumor; CD3 Complex; Chronic Disease; Cross-Sectional Studies; Disease Progression; Enzyme-Linked Immunosorbent Assay; Finasteride; Gene Expression Regulation; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Lower Urinary Tract Symptoms; Male; Molecular Chaperones; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Transurethral Resection of Prostate; Tumor Necrosis Factor-alpha | 2015 |
Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Case-Control Studies; Finasteride; Humans; Inflammation; Male; Middle Aged; Prostate; Prostatic Neoplasms | 2016 |
The new insight of prostate-specific antigen reduction during finasteride therapy in aging men.
Topics: Aged; Asian People; Doxazosin; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 2016 |
Grade-dependent Response to Finasteride in Early Prostate Cancer.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2016 |
Adverse Effects of 5-Alpha Reductase Inhibitor Therapy in Men With Androgenetic Alopecia: Is There Cause for Concern?
Topics: 5-alpha Reductase Inhibitors; Alopecia; Dutasteride; Erectile Dysfunction; Finasteride; Humans; Insulin Resistance; Libido; Male; Osteoporosis; Prostatic Hyperplasia; Prostatic Neoplasms | 2016 |
Long-term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial.
Topics: 5-alpha Reductase Inhibitors; Administrative Claims, Healthcare; Aged; Clinical Trials as Topic; Depression; Finasteride; Follow-Up Studies; Humans; Lower Urinary Tract Symptoms; Male; Medical Record Linkage; Medicare; Middle Aged; Prostatic Neoplasms; Protective Factors; Risk Assessment; Risk Factors; Time Factors; United States | 2016 |
Re: 5α-Reductase Inhibitors and the Risk of Cancer-Related Mortality in Men with Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Oxidoreductases; Prostatic Neoplasms | 2016 |
Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Epithelial Cells; Fibroblasts; Finasteride; Gene Expression Regulation, Neoplastic; Genes, jun; Humans; Insulin-Like Growth Factor I; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Prostatic Neoplasms | 2017 |
Jim's Prostate Cancer.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Clinical Decision-Making; Disease Progression; Finasteride; Humans; Kallikreins; Male; Neoplasm Grading; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Treatment Outcome; Watchful Waiting | 2017 |
Cancer Targeting Potential of
Topics: Acid Phosphatase; Animals; Carcinogenesis; Carcinogens; Disease Models, Animal; Electrophoresis; Finasteride; Hydrogen-Ion Concentration; Kinetics; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Technetium; Time Factors; Tissue Distribution | 2017 |
Finasteride for prevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms | 2008 |
Evaluation of MENT on primary cell cultures from benign prostatic hyperplasia and prostate carcinoma.
Topics: Androgens; Dihydrotestosterone; Finasteride; Humans; Male; Nandrolone; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Testosterone Congeners | 2009 |
Preventing prostate cancer: new analyses put finasteride back on the map.
Topics: 5-alpha Reductase Inhibitors; Anticarcinogenic Agents; Azasteroids; Bias; Biopsy, Needle; Carcinogens; Confounding Factors, Epidemiologic; Drug Approval; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Patents as Topic; Prostatic Hyperplasia; Prostatic Neoplasms; Severity of Illness Index; United States; United States Food and Drug Administration | 2008 |
A 49-year-old Hispanic male with intraepithelial neoplasia and focal atypia.
Topics: Biopsy; Enzyme Inhibitors; Expert Testimony; Finasteride; Hispanic or Latino; Humans; Male; Middle Aged; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Surgery, Computer-Assisted; Ultrasonography | 2008 |
New study makes case for prostate cancer drug.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2008 |
Does Proscar prevent prostate cancer?
Topics: Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 2008 |
High-grade prostate cancer and the prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome; Tumor Burden | 2008 |
Finasteride and high-grade prostate cancer.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostatic Neoplasms | 2009 |
Editorial comment on: Pharmacological approaches to reducing the risk of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Chemoprevention; Finasteride; Humans; Male; Primary Prevention; Prognosis; Prostatic Neoplasms; Risk Assessment; Treatment Outcome | 2009 |
Editorial comment on: Pharmacological approaches to reducing the risk of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Azasteroids; Biopsy, Needle; Chemoprevention; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Primary Prevention; Prognosis; Prostatic Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome | 2009 |
Editorial comment.
Topics: Aged; Biopsy; Enzyme Inhibitors; Finasteride; Health Education; Humans; Male; Marketing of Health Services; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms | 2009 |
Guideline supports long-term use of medication to lower prostate cancer risk.
Topics: 5-alpha Reductase Inhibitors; Aged; Enzyme Inhibitors; Finasteride; Guidelines as Topic; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms | 2009 |
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.
Topics: Androgen Antagonists; Androgens; Anilides; Animals; Castration; Cell Line, Tumor; Cinnamates; Disease Progression; Drug Combinations; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mifepristone; Molecular Structure; Neoplasm Transplantation; Nitriles; Progesterone; Prostatic Neoplasms; Steroids; Tosyl Compounds; Transplantation, Heterologous | 2009 |
Continuous finasteride therapy for benign prostate hypertrophy upgrades both neuroendorcine differentiation and aggressive prostate cancer.
Topics: Cell Differentiation; Enzyme Inhibitors; Finasteride; Humans; Male; Neurosecretory Systems; Prostatic Hyperplasia; Prostatic Neoplasms | 2009 |
Combined effect of the finasteride and doxazosin on rat ventral prostate morphology and physiology.
Topics: Androgens; Animals; Cell Proliferation; Dihydrotestosterone; Doxazosin; Epithelial Cells; Extracellular Matrix; Finasteride; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Wistar; RNA, Messenger; Testosterone; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1 | 2010 |
Finasteride treatment alters MMP-2 and -9 gene expression and activity in the rat ventral prostate.
Topics: Androgens; Animals; Extracellular Matrix; Finasteride; Gene Expression; Genes; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Finasteride to prevent prostate cancer: a new chapter.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Dutasteride; Finasteride; Humans; Male; Middle Aged; Practice Guidelines as Topic; Prostatic Neoplasms; Testosterone | 2009 |
The influence of prostate volume on prostate-specific antigen performance: implications for the prostate cancer prevention trial outcomes.
Topics: Aged; Biopsy; Diagnosis, Differential; Enzyme Inhibitors; Finasteride; Humans; Logistic Models; Male; Middle Aged; Outcome Assessment, Health Care; Predictive Value of Tests; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies | 2009 |
Alcohol consumption, finasteride, and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
Topics: Aged; Alcohol Drinking; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk | 2009 |
Is it worth the wait?
Topics: Antineoplastic Agents; Azasteroids; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2009 |
Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish Prostate Cancer Screening Trial.
Topics: Adrenergic alpha-Antagonists; Aged; Cohort Studies; Data Interpretation, Statistical; Finasteride; Finland; Follow-Up Studies; Humans; Incidence; Male; Mass Screening; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Time Factors | 2009 |
Guideline for 5-alpha-reductase inhibitors in the prevention of prostate cancer is premature.
Topics: Antineoplastic Agents; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2009 |
Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model.
Topics: Androgen Antagonists; Androgens; Animals; Cell Cycle; Cell Line, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Finasteride; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Orchiectomy; Prostatic Neoplasms; Survival Analysis; Testosterone; Time Factors; Xenograft Model Antitumor Assays | 2010 |
Prostate cancer prevention (AUGUST 2009).
Topics: Azasteroids; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2009 |
Testosterone replacement in prostate cancer survivors with hypogonadal symptoms.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Azasteroids; Dutasteride; Enzyme Inhibitors; Finasteride; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Survivors; Testosterone | 2010 |
Finasteride to prevent prostate cancer: should all men or only a high-risk subgroup be treated?
Topics: Aged; Decision Support Techniques; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Risk | 2010 |
Transparency and reproducibility in data analysis: the Prostate Cancer Prevention Trial.
Topics: Biopsy; Clinical Trials as Topic; Data Interpretation, Statistical; Digital Rectal Examination; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Reproducibility of Results | 2010 |
Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.
Topics: Anilides; Antineoplastic Agents; Azasteroids; Cell Differentiation; Cell Line, Tumor; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; Tosyl Compounds | 2010 |
Chemoprevention of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Biopsy; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Risk | 2010 |
Prostate cancer chemoprevention: what is the role of oncology nurses?
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents; Finasteride; Humans; Male; Middle Aged; Nurse's Role; Oncology Nursing; Patient Selection; Practice Guidelines as Topic; Prostatic Neoplasms | 2010 |
Saturable binding of finasteride to steroid 5alpha-reductase as determinant of nonlinear pharmacokinetics.
Topics: 5-alpha Reductase Inhibitors; Animals; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Male; Nonlinear Dynamics; Prostatic Hyperplasia; Prostatic Neoplasms; Rats | 2010 |
Consequences of switching 5alpha-reductase inhibitors on prostate specific antigen velocity.
Topics: Aged; Azasteroids; Chi-Square Distribution; Cholestenone 5 alpha-Reductase; Cholinergic Antagonists; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Linear Models; Male; Phosphodiesterase Inhibitors; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Quality of Life | 2010 |
Differential expression of steroid 5alpha-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Angiogenic Proteins; Azasteroids; Biomarkers, Tumor; Blotting, Western; Bone Neoplasms; Cell Nucleus; Cell Proliferation; Dutasteride; Enzyme-Linked Immunosorbent Assay; Finasteride; Gene Expression Profiling; Humans; Immunoenzyme Techniques; Isoenzymes; Lymphatic Metastasis; Male; Membrane Proteins; Middle Aged; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Array Analysis; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2010 |
Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice.
Topics: Androgens; Animals; Azasteroids; Cell Division; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Dutasteride; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nuclear Proteins; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Trans-Activators; Transplantation, Heterologous; Tumor Suppressor Proteins | 2010 |
Prostate cancer: finasteride extends PSA doubling time during intermittent hormone therapy.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Time Factors | 2010 |
Editorial comment.
Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2010 |
Can chemoprevention reduce the risk of prostate cancer?
Topics: Anticarcinogenic Agents; Azasteroids; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Risk | 2010 |
Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5alpha-reductase II.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Antagonists; Cell-Free System; Drug Evaluation, Preclinical; Finasteride; HEK293 Cells; Humans; In Vitro Techniques; Male; Plant Extracts; Prostatic Hyperplasia; Prostatic Neoplasms; Serenoa | 2010 |
[The influence of benign prostatic hyperplasia drugs on incidence and pathology grading of prostate cancer].
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Finasteride; Humans; Incidence; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies | 2010 |
An in vitro model for preclinical testing of endocrine therapy combinations for prostate cancer.
Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Cholesterol Side-Chain Cleavage Enzyme; Disease Progression; DNA Primers; Finasteride; Humans; In Situ Hybridization, Fluorescence; Male; Mice; Mice, SCID; Polymerase Chain Reaction; Prostatic Neoplasms; RNA, Messenger; Serine Endopeptidases; Steroids | 2010 |
Knowledge and use of finasteride for the prevention of prostate cancer.
Topics: Anticarcinogenic Agents; Data Collection; Finasteride; Humans; Incidence; Male; Practice Patterns, Physicians'; Prescriptions; Prostatic Neoplasms; United States; United States Department of Veterans Affairs | 2010 |
Evolving role of 5-alpha reductase inhibitors in chemoprevention.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Dutasteride; Finasteride; Humans; Male; Primary Prevention; Prostatic Hyperplasia; Prostatic Neoplasms | 2010 |
Dutasteride and prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms | 2010 |
Battling prostate cancer with 5-alpha-reductase inhibitors: a pyrrhic victory?
Topics: 5-alpha Reductase Inhibitors; Aged; Azasteroids; Chemoprevention; Dutasteride; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
Effects of family history and genetic polymorphism on the cost-effectiveness of chemoprevention with finasteride for prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Cost-Benefit Analysis; Finasteride; Humans; Male; Middle Aged; Polymorphism, Genetic; Prostatic Neoplasms | 2011 |
Effect of finasteride on the sensitivity of PSA to detect prostate cancer in rebiopsy series.
Topics: 5-alpha Reductase Inhibitors; Aged; Biopsy; Finasteride; Humans; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Sensitivity and Specificity | 2010 |
Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Estradiol; Estrone; Female; Finasteride; Humans; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms; Risk Factors | 2011 |
The risks and benefits of 5α-reductase inhibitors for prostate-cancer prevention.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Drug Approval; Dutasteride; Finasteride; Humans; Incidence; Male; Prostatic Neoplasms; United States; United States Food and Drug Administration | 2011 |
Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives.
Topics: Androgen Antagonists; Androgens; Androstanes; Androstenes; Androstenols; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Diosgenin; Dose-Response Relationship, Drug; Finasteride; Humans; Inhibitory Concentration 50; Lethal Dose 50; Macrophages; Male; Mice; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2011 |
5-α reductase inhibitors and prostate cancer prevention: where do we turn now?
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Chemoprevention; Drug Approval; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome; United States; United States Food and Drug Administration | 2011 |
What's wrong with chemoprevention of prostate cancer?
Topics: 5-alpha Reductase Inhibitors; Advisory Committees; Aged; Antineoplastic Agents; Azasteroids; Biomarkers, Tumor; Chemoprevention; Cost of Illness; Dutasteride; Early Detection of Cancer; Evidence-Based Medicine; Finasteride; Humans; Informed Consent; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment | 2011 |
The effect of finasteride and dutasteride on the growth of WPE1-NA22 prostate cancer xenografts in nude mice.
Topics: Animals; Azasteroids; Body Weight; Cell Line, Tumor; Cell Survival; Dihydrotestosterone; Dutasteride; Finasteride; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Rats; Testosterone; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride.
Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha Reductase Inhibitors; Aldo-Keto Reductase Family 1 Member C3; Androgens; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Finasteride; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Prostatic Neoplasms; Testosterone | 2012 |
Effect of treatment with 5-α reductase inhibitors on progression in monitored men with favourable-risk prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Androgen Antagonists; Azasteroids; Biopsy; Disease Progression; Dutasteride; Finasteride; Humans; Lower Urinary Tract Symptoms; Male; Middle Aged; Prospective Studies; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies | 2012 |
Prostate cancer in elderly Croatian men: 5-HT genetic polymorphisms and the influence of androgen deprivation therapy on osteopenia--a pilot study.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Bone Density; Bone Diseases, Metabolic; Finasteride; Flutamide; Gene Frequency; Genotype; Humans; Male; Pilot Projects; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptor, Serotonin, 5-HT1B; Serotonin | 2012 |
The use of the finasteride-adjusted Prostate Cancer Prevention Trial Prostate Cancer Risk Calculator in a Mexican referral population: a validation study.
Topics: 5-alpha Reductase Inhibitors; Age Factors; Aged; Antineoplastic Agents, Hormonal; Biopsy; Chi-Square Distribution; Digital Rectal Examination; Finasteride; Genetic Predisposition to Disease; Humans; Incidence; Logistic Models; Male; Mass Screening; Mexico; Middle Aged; Multivariate Analysis; Neoplasm Grading; Odds Ratio; Pedigree; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms; Referral and Consultation; Reproducibility of Results; Retrospective Studies; Risk Assessment; Risk Factors | 2012 |
The large sample bounds on the principal strata effect with application to a prostate cancer prevention trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Bias; Biostatistics; Finasteride; Humans; Male; Middle Aged; Models, Statistical; Multicenter Studies as Topic; Prevalence; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2012 |
A population-based nested case-control study in taiwan: use of 5α-reductase inhibitors did not decrease prostate cancer risk in patients with benign prostate hyperplasia.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Taiwan | 2012 |
Finasteride and prostate cancer: a commentary.
Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2012 |
Does variation in either age at start of therapy or duration of therapy make chemoprevention with finasteride cost-effective?
Topics: Age Factors; Aged; Chemoprevention; Cost-Benefit Analysis; Finasteride; Health Care Costs; Humans; Male; Markov Chains; Middle Aged; Prostatic Neoplasms; Quality-Adjusted Life Years | 2012 |
Prostate biopsy in response to a change in nadir prostate specific antigen of 0.4 ng/ml after treatment with 5α-reductase inhibitors markedly enhances the detection rate of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Biopsy; Dutasteride; Finasteride; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 2012 |
Expectant management of localized prostate cancer--who, what, when, where and how?
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Dutasteride; Finasteride; Humans; Male; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Quality Assurance, Health Care; Watchful Waiting | 2012 |
[Histopathology reports of findings of prostate needle biopsies. Individual treatment].
Topics: Adenocarcinoma; Attitude of Health Personnel; Biomarkers, Tumor; Biopsy, Needle; Cell Proliferation; Cooperative Behavior; Decision Support Techniques; Disease Progression; Finasteride; Germany; Guideline Adherence; Humans; Interdisciplinary Communication; Male; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Palliative Care; Patient Care Planning; Phosphodiesterase 5 Inhibitors; Precision Medicine; Prognosis; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Surveys and Questionnaires | 2013 |
Treatment with finasteride and prostate cancer survival.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Denmark; Dose-Response Relationship, Drug; Drug Therapy, Combination; Finasteride; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Proportional Hazards Models; Prostatic Neoplasms; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome | 2013 |
Prostate cancer chemoprevention with 5α-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Chemoprevention; Dutasteride; Finasteride; Humans; Male; Neoplasm Grading; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
The effects of dutasteride and finasteride on BPH-related hospitalization, surgery and prostate cancer diagnosis: a record-linkage analysis.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Aged, 80 and over; Azasteroids; Cohort Studies; Dutasteride; Finasteride; Follow-Up Studies; Hospitalization; Humans; Incidence; Lower Urinary Tract Symptoms; Male; Medical Record Linkage; Middle Aged; Proportional Hazards Models; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies; Risk Factors; Treatment Outcome | 2013 |
High-grade prostate cancer and biochemical recurrence after radical prostatectomy among men using 5α-reductase inhibitors and alpha-blockers.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-1 Receptor Antagonists; Azasteroids; Cohort Studies; Disease-Free Survival; Dutasteride; Finasteride; Finland; Humans; Kallikreins; Male; Neoplasm Grading; Neoplasm Recurrence, Local; Proportional Hazards Models; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quinazolines; Sulfonamides; Survival Rate; Tamsulosin | 2013 |
Unusual anti-angiogenic effect of combined hormonal blockade.
Topics: Aged; Angiogenesis Inhibitors; Anilides; Antineoplastic Agents, Hormonal; Capillaries; Chemotherapy, Adjuvant; Drug Therapy, Combination; Finasteride; Humans; Leuprolide; Male; Neoplasm Recurrence, Local; Nitriles; Prostatic Neoplasms; Skin; Telangiectasis; Tosyl Compounds; Treatment Outcome | 2002 |
Effect of nonsteroidal anti-inflammatory agents and finasteride on prostate cancer risk.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Case-Control Studies; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk | 2002 |
Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Brachytherapy; Chemotherapy, Adjuvant; Diarrhea; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Logistic Models; Male; Nitriles; Penile Erection; Prostatic Neoplasms; Quality of Life; Tosyl Compounds; Treatment Outcome; Urinary Incontinence | 2003 |
[Dual 5-alpha reductase inhibitors in BPH (benign prostatic hyperplasia). Already after 1 month prostate shrinks].
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Clinical Trials, Phase III as Topic; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Infant, Newborn; Male; Placebos; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors; Testosterone; Time Factors; Ultrasonography | 2003 |
Supplements and the prostate: widespread use, little evidence.
Topics: Adult; Aged; Antioxidants; Clinical Trials as Topic; Dietary Supplements; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Selenium; Sensitivity and Specificity; Vitamin E; Vitamins | 2003 |
Re: Effect of nonsteroidal anti-inflammatory agents and finasteride on prostate cancer risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Finasteride; Humans; Male; Prostatic Neoplasms; Risk | 2003 |
Chemoprevention for prostate cancer - the way forward?
Topics: Antineoplastic Agents; Chemoprevention; Finasteride; Humans; Male; Prostatic Neoplasms | 2003 |
The impact of prostate volume following neoadjuvant androgen deprivation on quality of life and voiding symptoms in patients undergoing permanent prostate brachytherapy.
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Brachytherapy; Cross-Sectional Studies; Finasteride; Humans; Leuprolide; Male; Middle Aged; Neoadjuvant Therapy; Prostate; Prostatic Neoplasms; Quality of Life; Surveys and Questionnaires; Urination Disorders | 2003 |
Re: Effect of nonsteroidal anti-inflammatory agents and finasteride on prostate cancer risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Finasteride; Humans; Male; Prostatic Neoplasms | 2003 |
The prevention of prostate cancer--the dilemma continues.
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents, Hormonal; Finasteride; Humans; Male; Prostatic Neoplasms; Risk Assessment | 2003 |
Stat bite: Estimated effect of finasteride on prostate cancer development.
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Finasteride; Humans; Incidence; Male; Middle Aged; Multicenter Studies as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Severity of Illness Index; United States | 2003 |
Prostate cancer prevention trial yields positive results, but with a few cautions.
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemoprevention; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Multicenter Studies as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Severity of Illness Index; Testosterone | 2003 |
A big study yields big questions.
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents, Hormonal; Clinical Trials as Topic; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Risk | 2003 |
Pharmaceutical review.
Topics: Adrenergic alpha-Antagonists; Doxazosin; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Risk Assessment; Urinary Retention | 2003 |
Study of prostate cancer prevention drug shows potential and problems.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; United States | 2003 |
Chemoprevention for prostate cancer: the Prostate Cancer Prevention Trial.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors | 2003 |
Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma.
Topics: Case-Control Studies; Cholestenone 5 alpha-Reductase; Databases, Genetic; Enzyme Inhibitors; Finasteride; Gene Expression; Gene Expression Profiling; Humans; Male; Nucleic Acid Amplification Techniques; Oligonucleotide Array Sequence Analysis; Oxidoreductases; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Finasteride may prevent prostate cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms | 2003 |
Preventing prostate cancer. Finasteride shrinks enlarged prostates and may prevent some cases of prostate cancer. But it's no panacea.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Prostatic Neoplasms; Risk | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Finasteride; Gynecomastia; Humans; Male; Prostatic Neoplasms | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Risk; Testosterone | 2003 |
Prevention of prostate cancer with finasteride.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms; Ultrasonography | 2003 |
Preventing prostate cancer with finasteride: a mixed blessing.
Topics: 5-alpha Reductase Inhibitors; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2003 |
Mixed reviews for drug studied to prevent prostate cancer.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Risk | 2003 |
Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Antagonists; Apoptosis; Azasteroids; Cell Division; Dose-Response Relationship, Drug; Dutasteride; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Finasteride; Humans; Ligands; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Tumor Cells, Cultured | 2004 |
Male breast cancer during finasteride therapy.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms, Male; Carcinoma, Ductal; Doxazosin; Drug Labeling; Enzyme Inhibitors; Finasteride; Gynecomastia; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic; United States | 2004 |
Herbal and vitamin supplement use in a prostate cancer screening population.
Topics: Adenocarcinoma; Adrenergic alpha-Antagonists; Adult; Aged; Colorado; Complementary Therapies; Dietary Supplements; Doxazosin; Drug Utilization; Family; Finasteride; Health Surveys; Humans; Male; Mass Screening; Middle Aged; Penile Erection; Phytotherapy; Plant Preparations; Prazosin; Prostatic Hyperplasia; Prostatic Neoplasms; Self Medication; Socioeconomic Factors; Sulfonamides; Surveys and Questionnaires; Tamsulosin; Urination Disorders; Vitamins | 2004 |
Third annual meeting of the Society of Urologic Oncology: Bethesda, Maryland, December 13-14, 2002.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Medical Oncology; Prostate-Specific Antigen; Prostatic Neoplasms; Societies, Medical; Urology | 2003 |
[Finasteride and prostate cancer].
Topics: Finasteride; Finland; Humans; Male; Monitoring, Physiologic; Prognosis; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms | 2004 |
The biological basis for the use of an anti-androgen and a 5-alpha-reductase inhibitor in the treatment of recurrent prostate cancer: Case report and review.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Androgen Antagonists; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tumor Cells, Cultured | 2004 |
The clinical implications of the Prostate Cancer Prevention Trial (PCPT).
Topics: Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2004 |
Finasteride and bicalutamide as primary hormonal therapy in patients with advanced adenocarcinoma of the prostate.
Topics: Adenocarcinoma; Aged; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Erectile Dysfunction; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Nitriles; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds | 2004 |
Re: Thompson IM, Klein EA, Lippman SM, Coltman CA, Djavan B. Prevention of prostate cancer with finasteride: US/European perspective. Eur Urol 2003;44:650-5.
Topics: Enzyme Inhibitors; Europe; Finasteride; Humans; Male; Prostatic Neoplasms; United States | 2004 |
Finasteride (Propecia) and the promotion of high-grade prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2004 |
[Therapy of benign prostatic hyperplasia with finasteride and doxazosin -- long-term studies support the combination].
Topics: Adrenergic alpha-Antagonists; Controlled Clinical Trials as Topic; Disease Progression; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Placebos; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Assessment; Risk Factors; Time Factors | 2004 |
Despite positive studies, popularity of chemoprevention drugs increasing slowly.
Topics: Adenomatous Polyposis Coli; Androgen Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Celecoxib; Cell Transformation, Neoplastic; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Prescriptions; Female; Finasteride; Humans; Male; Neoplasms; Prostatic Neoplasms; Pyrazoles; Sulfonamides; Tamoxifen; United States | 2004 |
Re: inflammation as a target for prostate cancer chemoprevention: pathological and laboratory rationale.
Topics: Enzyme Inhibitors; Finasteride; Humans; Inflammation; Male; Prostatic Neoplasms | 2004 |
Serenoa repens (Permixon) inhibits the 5alpha-reductase activity of human prostate cancer cell lines without interfering with PSA expression.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Dihydrotestosterone; Finasteride; Humans; Male; Phytotherapy; Plant Extracts; Prostate-Specific Antigen; Prostatic Neoplasms; Serenoa; Testosterone | 2005 |
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.
Topics: Androstadienes; Androstanols; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Finasteride; Humans; Imidazoles; Male; Mice; Mice, SCID; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Time Factors; Transplantation, Heterologous; Triazoles | 2004 |
Proscar and propecia--a therapeutic perspective.
Topics: Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Risk Factors | 2004 |
Estrogen receptor beta in prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androstane-3,17-diol; Animals; Antineoplastic Agents, Hormonal; Estrogen Receptor beta; Finasteride; Humans; Ligands; Male; Mice; Prostatic Neoplasms | 2004 |
Evaluation of cell permeation of a potent 5alpha-reductase inhibitor using MALDI-TOF MS.
Topics: Benzoates; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Cholestenone 5 alpha-Reductase; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Esterases; Esters; Finasteride; Humans; Hydrolysis; Inhibitory Concentration 50; Male; Membranes, Artificial; Molecular Conformation; Piperidines; Prostatic Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Time Factors | 2004 |
Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.
Topics: 5-alpha Reductase Inhibitors; Aged; Androgens; Antineoplastic Agents, Hormonal; Azasteroids; Cell Line, Tumor; Cell Proliferation; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostatic Hyperplasia; Prostatic Neoplasms | 2005 |
[The PCPT study: the viewpoint of an urologist involved].
Topics: Cholestenone 5 alpha-Reductase; Clinical Trials as Topic; Finasteride; Humans; Male; Multicenter Studies as Topic; Prostatic Neoplasms; Time Factors; Urology | 2004 |
[Use of 5-alpha-reductase inhibitors in the prevention of prostate cancer].
Topics: Aged; Azasteroids; Cholestenone 5 alpha-Reductase; Clinical Trials as Topic; Dutasteride; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms | 2004 |
Gleason grade remains an important prognostic predictor in men diagnosed with prostate cancer while on finasteride therapy.
Topics: Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Neoplasm Staging; Nomograms; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Urination Disorders | 2005 |
Estimated impact of the Prostate Cancer Prevention Trial on population mortality.
Topics: Finasteride; Humans; Incidence; Male; Middle Aged; Models, Statistical; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2005 |
RE: Effect of the dual 5alpha-reductase inhibitor dutasteride on markers of tumor regression in prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Apoptosis; Azasteroids; Biomarkers, Tumor; Dihydrotestosterone; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2005 |
Undetectable prostate specific antigen at 6-12 months: a new marker for early success in hormonally treated patients after prostate brachytherapy.
Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Brachytherapy; Combined Modality Therapy; Enzyme Inhibitors; Finasteride; Humans; Leuprolide; Male; Neoadjuvant Therapy; Neoplasm Staging; Palladium; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Risk Factors; Survival Rate; Testosterone; Treatment Outcome; Ultrasonography, Interventional | 2005 |
Role of 5a-reductase inhibitors and selective estrogen receptor modulators as potential chemopreventive agents for prostate cancer.
Topics: Antineoplastic Agents, Hormonal; Chemoprevention; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Toremifene | 2005 |
Clinical trials point to complexities of chemoprevention for cancer.
Topics: Aspirin; Breast Neoplasms; Clinical Trials as Topic; Diet; Dihydrotestosterone; Female; Finasteride; Humans; Male; Neoplasms; Prostatic Neoplasms; Selective Estrogen Receptor Modulators; Tamoxifen; Vitamin E | 2005 |
Estimated impact of the prostate cancer prevention trial on population mortality.
Topics: Age Distribution; Aged; Case-Control Studies; Disease-Free Survival; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome; United States | 2005 |
[Mechanism of inhibiting the proliferation of prostate cancer by finasteride: a study using cDNA microarray].
Topics: Antigens, Neoplasm; Biomarkers, Tumor; Cell Line, Tumor; Finasteride; Gene Expression Profiling; Humans; Male; Neoplasms, Hormone-Dependent; Oligonucleotide Array Sequence Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction | 2005 |
Lifetime implications and cost-effectiveness of using finasteride to prevent prostate cancer.
Topics: Aged; Aged, 80 and over; Cost-Benefit Analysis; Enzyme Inhibitors; Finasteride; Humans; Male; Markov Chains; Middle Aged; Models, Econometric; Prostatic Neoplasms; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; United States | 2005 |
Assessing benefit and risk in the prevention of prostate cancer: the prostate cancer prevention trial revisited.
Topics: Adenocarcinoma; Biopsy, Needle; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Odds Ratio; Prognosis; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome | 2005 |
Rebalancing ratios and improving impressions: later thoughts from the prostate cancer prevention trial investigators.
Topics: Adenocarcinoma; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Treatment Outcome | 2005 |
Effects of long-term finasteride treatment on prostate cancer morphology and clinical outcome.
Topics: Adult; Aged; Aged, 80 and over; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Time Factors; Treatment Outcome | 2005 |
Enhancement of intermittent androgen ablation by "off-cycle" maintenance with finasteride in LNCaP prostate cancer xenograft model.
Topics: Androgens; Animals; Cell Cycle; Cell Line, Tumor; Enzyme Inhibitors; Finasteride; Humans; Male; Mice; Mice, Nude; Orchiectomy; Prostatic Neoplasms; Transplantation, Heterologous | 2006 |
Do the benefits of finasteride outweigh the risks in the prostate cancer prevention trial?
Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Markov Chains; Middle Aged; Models, Theoretical; Prostatic Neoplasms; Risk Assessment; Time Factors | 2006 |
Finasteride: middle-age cure-all for alopecia and benign prostatic hyperplasia?
Topics: 5-alpha Reductase Inhibitors; Alopecia; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms | 2006 |
[Prostate carcinoma: can 5-alpha reductase inhibitors prevent it?].
Topics: 5-alpha Reductase Inhibitors; Azasteroids; Controlled Clinical Trials as Topic; Dutasteride; Finasteride; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prostatic Neoplasms; Treatment Outcome | 2005 |
Androgen-deprivation therapy as primary treatment for localized prostate cancer: data from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE).
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Diethylstilbestrol; Enzyme Inhibitors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Longitudinal Studies; Male; Middle Aged; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Survival Rate | 2006 |
Intermittent use of testosterone inactivating pharmaceuticals using finasteride prolongs the time off period.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Time Factors | 2006 |
Finasteride targets prostate vascularity by inducing apoptosis and inhibiting cell adhesion of benign and malignant prostate cells.
Topics: Apoptosis; Cell Adhesion; Cells, Cultured; Factor VIII; Finasteride; Humans; In Situ Nick-End Labeling; Male; Microcirculation; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Retrospective Studies; Tumor Cells, Cultured | 2006 |
Re: Long-term effects of finasteride on prostate specific antigen levels: results from the Prostate Cancer Prevention Trial.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2006 |
Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Administration, Oral; Animals; Azasteroids; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Enzyme Activation; Enzyme Inhibitors; Finasteride; Gene Expression Profiling; Humans; Male; Mass Spectrometry; Mice; Mice, Nude; Molecular Conformation; Prostatic Neoplasms; Protein Isoforms; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2006 |
The cost of prostate cancer chemoprevention: a decision analysis model.
Topics: Aged; Chemoprevention; Cost-Benefit Analysis; Decision Support Techniques; Enzyme Inhibitors; Finasteride; Health Care Costs; Health Services Research; Humans; Male; Markov Chains; Middle Aged; Models, Econometric; Prostatic Neoplasms; Sensitivity and Specificity | 2006 |
New finasteride trial results aim to curb controversy.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2006 |
Benign prostatic hyperplasia: caveat for finasteride should be discussed before prescribing.
Topics: Antineoplastic Agents; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2006 |
Chemoprevention in prostate cancer.
Topics: Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2006 |
The prostate cancer prevention trial and its messages.
Topics: 5-alpha Reductase Inhibitors; Early Diagnosis; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2007 |
New progesterone derivatives as inhibitors of 5alpha-reductase enzyme and prostate cancer cell growth.
Topics: Animals; Cell Line, Tumor; Cholestenone 5 alpha-Reductase; Cricetinae; Finasteride; Humans; Male; Mesocricetus; Models, Chemical; Progesterone; Prostate; Prostatic Neoplasms; Steroids; Testosterone | 2006 |
The evolution of the PCPT from clinical to molecular analyses.
Topics: Biopsy; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2006 |
Re: The Prostate Cancer Prevention Trial: design, biases and interpretation of study results. P. J. Goodman, I. M. Thompson, Jr., C. M. Tangen, J. J. Crowley, L. G. Ford and C. A. Coltman, Jr., J Urol, 175: 2234-2242, 2006.
Topics: Bias; Biopsy; Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design | 2006 |
Can effect of finasteride on prostate-specific antigen be used to decrease repeat prostate biopsy?
Topics: Aged; Biomarkers, Tumor; Biopsy; Diagnosis, Differential; Endosonography; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies | 2006 |
Prostate cancer risk among users of finasteride and alpha-blockers - a population based case-control study.
Topics: Adrenergic alpha-Antagonists; Case-Control Studies; Enzyme Inhibitors; Finasteride; Humans; Male; Odds Ratio; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Factors | 2007 |
New answers from the Prostate Cancer Prevention Trial on the chemoprevention of prostate cancer.
Topics: Clinical Trials as Topic; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2006 |
A large retrospective analysis of acute urinary retention and prostate-related surgery in BPH patients treated with 5-alpha reductase inhibitors: dutasteride versus finasteride.
Topics: Acute Disease; Age Distribution; Aged; Azasteroids; Dutasteride; Finasteride; Follow-Up Studies; Humans; Incidence; Male; Managed Care Programs; Middle Aged; Multivariate Analysis; Probability; Prostatectomy; Prostatic Neoplasms; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Urinary Retention; Urodynamics | 2007 |
Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Glands; Androgens; Cell Line, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model.
Topics: Adenocarcinoma; Androgen Antagonists; Animals; Animals, Genetically Modified; Antigens, Viral, Tumor; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Finasteride; Flutamide; Male; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone | 2007 |
[Chemoprevention of prostate cancer. Current status].
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Evidence-Based Medicine; Finasteride; Humans; Male; Prospective Studies; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators | 2007 |
Re: expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy. T. Kurahashi, H. Miyake, I. Hara and M. Fujisawa J Urol 2007; 177: 757-761.
Topics: 5-alpha Reductase Inhibitors; Disease Progression; Enzyme Inhibitors; Finasteride; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Male; Molecular Chaperones; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Quercetin; Up-Regulation | 2007 |
Quantifying the impact of prostate volumes, number of biopsy cores and 5alpha-reductase inhibitor therapy on the probability of prostate cancer detection using mathematical modeling.
Topics: 5-alpha Reductase Inhibitors; Biopsy; Finasteride; Humans; Male; Models, Theoretical; Organ Size; Predictive Value of Tests; Prostatic Neoplasms; Tumor Burden | 2007 |
Advances in the medical management of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Doxazosin; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2007 |
Finasteride for chemoprevention of prostate cancer: why has it not been embraced?
Topics: California; Chemoprevention; Early Diagnosis; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Mass Screening; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Analysis | 2007 |
High-grade prostate cancer in the Prostate Cancer Prevention Trial: fact or artifact?
Topics: Aged; Anticarcinogenic Agents; Bias; Biopsy, Needle; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Models, Statistical; Prostatectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome | 2007 |
[The Prostate Cancer Prevention Trial (PCPT). Relevance for clinical practice].
Topics: 5-alpha Reductase Inhibitors; Aged; Biomarkers, Tumor; Biopsy; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Long-Term Care; Male; Middle Aged; Neoplasm Staging; Prostate; Prostate-Specific Antigen; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Factors | 2007 |
Cost-effectiveness of prostate cancer chemoprevention: a quality of life-years analysis.
Topics: Cost-Benefit Analysis; Finasteride; Humans; Incidence; Male; Markov Chains; Middle Aged; Prostatic Neoplasms; Quality of Life; Quality-Adjusted Life Years; Survival Rate | 2008 |
Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Diet; Dietary Supplements; Feeding Behavior; Finasteride; Humans; Incidence; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prospective Studies; Prostatic Hyperplasia; Prostatic Neoplasms; Proteins; Risk Assessment; Risk Factors; Surveys and Questionnaires; United States | 2008 |
Finasteride therapy for benign prostatic hyperplasia.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2008 |
Open to debate. The Motion: all men over the age of 50 should be encouraged to take a 5alpha-reductase inhibitor to prevent prostate cancer.
Topics: Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Morbidity; Ontario; Prognosis; Prostatic Neoplasms; Risk Factors | 2008 |
The Prostate Cancer Prevention Trial and the future of chemoprevention.
Topics: Antineoplastic Agents; Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
Finasteride induces apoptosis via Bcl-2, Bcl-xL, Bax and caspase-3 proteins in LNCaP human prostate cancer cell line.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Cell Line, Tumor; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2 | 2008 |
Development and validation of an LC-MS assay for finasteride and its application to prostate cancer prevention trial sample analysis.
Topics: 5-alpha Reductase Inhibitors; Chromatography, High Pressure Liquid; Drug Stability; Finasteride; Humans; Male; Mass Spectrometry; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Reproducibility of Results; Sensitivity and Specificity | 2008 |
[The PCPT trial].
Topics: Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
[PCPT trial: expected bias and their management].
Topics: Bias; Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
[The pathologist's perspective on the PCPT trial].
Topics: Bias; Biopsy; Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Pathology; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
[Contribution of the PCPT trial to finasteride treatment of micturition disorders due to benign prostatic hyperplasia].
Topics: Chemoprevention; Decision Trees; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Urination Disorders | 2008 |
[Practical follow-up of a patient treated with finasteride in screening for prostate cancer].
Topics: Chemoprevention; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
[Relevance of chemoprevention from PCPT trial].
Topics: Chemoprevention; Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 2008 |
Does the level of prostate cancer risk affect cancer prevention with finasteride?
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Assessment; Risk Factors | 2008 |
Case records of the Massachusetts General Hospital. Case 15-2008. A 55-year-old man with an elevated prostate-specific antigen level and early-stage prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Urinary Retention | 2008 |
Effects of dutasteride on prostate carcinoma primary cultures: a comparative study with finasteride and MK386.
Topics: 5-alpha Reductase Inhibitors; Aged; Azasteroids; Cell Proliferation; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 2008 |
[Chemoprevention of cancer of the prostate].
Topics: Aged; Aged, 80 and over; Animals; Disease Models, Animal; Finasteride; Food; Humans; Male; Middle Aged; Prostatic Neoplasms; Rats; Rats, Wistar; Risk Factors | 1995 |
Treatment of advanced prostate cancer with the combination of finasteride plus flutamide: early results.
Topics: Aged; Drug Therapy, Combination; Erectile Dysfunction; Finasteride; Flutamide; Humans; Luteinizing Hormone; Male; Middle Aged; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 1993 |
Men's health issues.
Topics: Adrenergic alpha-Antagonists; Finasteride; Humans; Male; Prazosin; Prostatic Hyperplasia; Prostatic Neoplasms | 1993 |
Prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Anticarcinogenic Agents; Disease-Free Survival; Estrogens; Finasteride; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Lymphatic Metastasis; Male; Neoplasm Metastasis; Neoplasm Staging; Prevalence; Prostate-Specific Antigen; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Radiotherapy | 1994 |
Clinical development plan: Proscar.
Topics: Animals; Clinical Trials as Topic; Drug Approval; Female; Finasteride; Humans; Male; Mice; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley | 1994 |
Prostatic specific antigen (PSA)
Topics: Biomarkers, Tumor; Diagnosis, Differential; False Negative Reactions; Finasteride; Humans; Male; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Reference Values | 1993 |
Chemoprevention of rat prostate carcinogenesis by use of finasteride or casodex.
Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Finasteride; Male; Nitriles; Prostatic Neoplasms; Rats; Rats, Inbred F344; Tosyl Compounds | 1995 |
Finasteride dose-dependently reduces the proliferation rate of the LnCap human prostatic cancer cell line in vitro.
Topics: Androgen Antagonists; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Finasteride; Flutamide; Humans; Linear Models; Male; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured | 1995 |
Clinical review: 67: Approach to chemoprevention of prostate cancer.
Topics: Dihydrotestosterone; Finasteride; Humans; Male; Prostate; Prostatic Neoplasms | 1995 |
PCPT update: enrollment mounts, but minority participation lags.
Topics: Finasteride; Humans; Male; Minority Groups; Multicenter Studies as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic | 1994 |
Inhibition of the activity of 'basic' 5 alpha-reductase (type 1) detected in DU 145 cells and expressed in insect cells.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Baculoviridae; Brain Neoplasms; Chromatography, High Pressure Liquid; Dihydrotestosterone; Finasteride; Gene Expression; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Male; Moths; Prostatic Neoplasms; Recombinant Proteins; Testosterone; Tumor Cells, Cultured | 1994 |
Hormonal chemoprevention of cancer in women.
Topics: 5-alpha Reductase Inhibitors; Adult; Age Factors; Aged; Androstenes; Anticarcinogenic Agents; Azasteroids; Breast Neoplasms; Contraceptives, Oral; Endometrial Neoplasms; Estrogen Replacement Therapy; Female; Finasteride; Humans; Incidence; Male; Middle Aged; Ovarian Neoplasms; Progestins; Prostatic Neoplasms; Tamoxifen; United Kingdom; United States | 1993 |
Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenosarcoma; Androstenedione; Azasteroids; Blotting, Northern; Cells, Cultured; Cholestenone 5 alpha-Reductase; Chromatography, High Pressure Liquid; Dihydrotestosterone; Enzyme Inhibitors; Epithelium; Etiocholanolone; Fibroblasts; Finasteride; Humans; Male; Meningioma; Oxidoreductases; Placenta; Prostatic Neoplasms; RNA; RNA, Messenger; Testosterone; Tumor Cells, Cultured | 1995 |
Characterization of type I 5 alpha-reductase activity in DU145 human prostatic adenocarcinoma cells.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstadienes; Benzoquinones; Cell Division; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Male; Prostatic Neoplasms; RNA, Messenger; Selection, Genetic; Skin; Testosterone; Tumor Cells, Cultured | 1996 |
Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride.
Topics: Androgen-Binding Protein; Animals; Cell Division; Cell Line; Dihydrotestosterone; DNA Primers; Drug Implants; Enzyme Inhibitors; Estradiol; Finasteride; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Nude; Orchiectomy; Polymerase Chain Reaction; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone; Time Factors; Transplantation, Heterologous | 1996 |
Clinical trials referral resource. Breast cancer and prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Adult; Anticarcinogenic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Finasteride; Humans; Male; Prostatic Neoplasms; Tamoxifen | 1996 |
Evaluation of prostatic intraepithelial neoplasia after treatment with a 5-alpha-reductase inhibitor (finasteride). A methodologic approach.
Topics: 5-alpha Reductase Inhibitors; Aged; Bayes Theorem; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 1996 |
Anti-androgenic effects of combination finasteride plus flutamide in patients with prostatic carcinoma.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Follow-Up Studies; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 1996 |
Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Leuprolide; Luteinizing Hormone; Male; Organ Size; Pituitary Gland, Anterior; Prostate; Prostatic Neoplasms; Random Allocation; Rats; Seminal Vesicles; Testis; Testosterone | 1997 |
Effects of chlormadinone acetate and ethinylestradiol treatment on epididymal 5 alpha-reductase activities in patients with prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Antineoplastic Agents, Hormonal; Chlormadinone Acetate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epididymis; Ethinyl Estradiol; Finasteride; Humans; Male; Orchiectomy; Prostatic Neoplasms | 1997 |
Anaemia associated with androgen deprivation in patients with prostate cancer receiving combined hormone blockade.
Topics: Age Factors; Aged; Anemia; Anilides; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Hemoglobins; Humans; Male; Nitriles; Prospective Studies; Prostatic Neoplasms; Testosterone; Time Factors; Tosyl Compounds | 1997 |
Finasteride plus flutamide for prostatic carcinoma.
Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Male; Prostatic Neoplasms | 1997 |
Tamoxifen for flutamide/finasteride-induced gynecomastia.
Topics: Aged; Androgen Antagonists; Drug Evaluation; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Finasteride; Flutamide; Gynecomastia; Humans; Male; Middle Aged; Prostatic Neoplasms; Tamoxifen; Testosterone; Time Factors | 1997 |
A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Aminobiphenyl Compounds; Androgen Antagonists; Anilides; Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Finasteride; Male; Nitriles; Prostatic Neoplasms; Rats; Rats, Inbred F344; Testosterone; Tosyl Compounds | 1998 |
Biologic variability of prostate-specific antigen and its usefulness as a marker for prostate cancer: effects of finasteride. Finasteride PSA Study Group.
Topics: Adult; Aged; Biomarkers, Tumor; Enzyme Inhibitors; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms | 1998 |
Effect of early treatment of prostate cancer with the 5alpha-reductase inhibitor turosteride in Dunning R3327 prostatic carcinoma in rats.
Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Animals; Cell Line; Drug Administration Schedule; Enzyme Inhibitors; Finasteride; Male; Orchiectomy; Organ Size; Prostate; Prostatic Neoplasms; Rats; Time Factors | 1998 |
[Use of transrectal ultrasonography in prostate pathology: determination and clinical usefulness of the prostate transition zone].
Topics: 5-alpha Reductase Inhibitors; Aged; Catheter Ablation; Diagnosis, Differential; Enzyme Inhibitors; Finasteride; Forecasting; Humans; Laser Coagulation; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Survival Rate; Ultrasonography | 1998 |
Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.
Topics: Androgens; Animals; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Ketoconazole; Male; Organ Size; Oxidoreductases; Prostate; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Testosterone | 1998 |
Urology.
Topics: Circumcision, Male; Enzyme Inhibitors; Erectile Dysfunction; Finasteride; Humans; Male; Mass Screening; Pain; Piperazines; Plant Extracts; Prostatic Hyperplasia; Prostatic Neoplasms; Purines; Serenoa; Sildenafil Citrate; Sulfones; Urology | 1999 |
Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: results of a randomized, double-blind, placebo-controlled clinical trial.
Topics: Double-Blind Method; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Reproducibility of Results | 1999 |
'Clandestine' prostate cancer haunts.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy; Combined Modality Therapy; Diagnostic Errors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Prostate; Prostatectomy; Prostatic Neoplasms | 1996 |
Anaemia in men receiving combined finasteride and flutamide therapy for advanced prostate cancer.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Enzyme Inhibitors; Finasteride; Flutamide; Hematocrit; Hemoglobins; Humans; Male; Middle Aged; Prostatic Neoplasms; Testosterone | 1999 |
Immunohistochemical expression of pi class glutathione S-transferase in the basal cell layer of benign prostate tissue following chronic treatment with finasteride.
Topics: Aged; Drug Administration Schedule; Enzyme Inhibitors; Finasteride; Glutathione Transferase; Humans; Immunoenzyme Techniques; Male; Middle Aged; Prostate; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Up-Regulation | 1999 |
Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia.
Topics: Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 6; Enzyme Inhibitors; Finasteride; Humans; In Situ Hybridization, Fluorescence; Male; Neoplasm Staging; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; X Chromosome | 1999 |
Re: Chemoprevention of urological cancer.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Prostatic Neoplasms | 2000 |
Chemoprevention: an important treatment option for prostate cancer.
Topics: Aged; Antioxidants; Enzyme Inhibitors; Finasteride; Humans; Incidence; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selenium; United States; Vitamin E | 2000 |
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Cell Division; Chlorocebus aethiops; Finasteride; Growth Inhibitors; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms, Hormone-Dependent; Oleanolic Acid; Pregnadienes; Prostatic Neoplasms; Receptors, Androgen; Saponins; Steroid 17-alpha-Hydroxylase; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2000 |
Prostate cancer prevention agent development: Criteria and pipeline for candidate chemoprevention agents.
Topics: Androgen Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Cell Differentiation; Cell Division; Drug Evaluation; Estrogen Receptor Modulators; Finasteride; Genetic Therapy; Growth Substances; Humans; Male; Middle Aged; Prostatic Neoplasms; Signal Transduction | 2001 |
Androgen antagonists: Potential role in prostate cancer prevention.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Benzoquinones; Enzyme Inhibitors; Finasteride; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2001 |
As genes differ, so should interventions for cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Antineoplastic Agents; Enzyme Inhibitors; Finasteride; Genetic Predisposition to Disease; Humans; Male; Prostatic Neoplasms | 2001 |
Novel antineoplastic isochalcones inhibit the expression of cyclooxygenase 1,2 and EGF in human prostate cancer cell line LNCaP.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Finasteride; Growth Inhibitors; Humans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostate; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured | 2001 |
Prostatic intraepithelial neoplasia and putative precursor lesions of prostate cancer: a clinical perspective.
Topics: Enzyme Inhibitors; Finasteride; Humans; Male; Precancerous Conditions; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Risk Factors | 2001 |
Optimism expressed over prostate drug.
Topics: Androstenes; Antineoplastic Agents; Azasteroids; Dihydrotestosterone; Finasteride; Humans; Male; Pilot Projects; Prostatic Hyperplasia; Prostatic Neoplasms; Recurrence | 1991 |
Effect of castration, DES, flutamide, and the 5 alpha-reductase inhibitor, MK-906, on the growth of the Dunning rat prostatic carcinoma, R-3327.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenes; Animals; Azasteroids; Diethylstilbestrol; Finasteride; Flutamide; Male; Orchiectomy; Prostatic Neoplasms; Rats; Rats, Inbred F344 | 1991 |