fidexaban has been researched along with Disease Models, Animal in 3 studies
Fidexaban: structure in first source
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, five of six animals given the lowest effective dosage of rTAP and four of six animals given DX-9065a bled from a surgical incision >5 min, but only two of six animals given ZK-807834 bled >5 min." | 1.31 | Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits. ( Abendschein, DR; Baum, PK; Eisenberg, PR; Light, DR; Martin, DJ; Post, J; Rumennik, G; Sullivan, ME; Vergona, R, 2000) |
| "The time to formation of an occlusive thrombus in the femoral arteries averaged 69+/-5 min in the control group compared to 127+/-19, 192+/-33 and 219+/-15 min in the low-, mid- and high-dose CI-1031 groups." | 1.31 | The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis. ( Hicks, GW; Janiczek-Dolphin, N; Juneau, PL; Leadley, R; McClanahan, TB; Mertz, TE; Morrison, AL; Morser, J; Peng, YW; Sullivan, ME, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abendschein, DR | 1 |
| Baum, PK | 1 |
| Martin, DJ | 1 |
| Vergona, R | 1 |
| Post, J | 1 |
| Rumennik, G | 1 |
| Sullivan, ME | 2 |
| Eisenberg, PR | 1 |
| Light, DR | 1 |
| McClanahan, TB | 1 |
| Hicks, GW | 1 |
| Morrison, AL | 1 |
| Peng, YW | 1 |
| Janiczek-Dolphin, N | 1 |
| Mertz, TE | 2 |
| Morser, J | 1 |
| Juneau, PL | 2 |
| Leadley, R | 2 |
| Chi, L | 1 |
| Pen, YW | 1 |
| Potoczak, R | 1 |
| Gibson, G | 1 |
| Hicks, G | 1 |
| Janiczek, N | 1 |
| Gallagher, K | 1 |
3 other studies available for fidexaban and Disease Models, Animal
| Article | Year |
|---|---|
Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits.
Topics: Amidines; Animals; Anticoagulants; Antithrombin III; Arthropod Proteins; Coronary Thrombosis; Diseas | 2000 |
The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis.
Topics: Amidines; Animals; Anticoagulants; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; E | 2001 |
Assessment of ex vivo pharmacodynamic markers during inhibition of thrombosis by CI-1031 (ZK-807834), a novel direct factor Xa inhibitor.
Topics: Amidines; Animals; Anticoagulants; Biomarkers; Blood Coagulation; Disease Models, Animal; Dose-Respo | 2002 |