Page last updated: 2024-10-31

fidexaban and Deep Vein Thrombosis

fidexaban has been researched along with Deep Vein Thrombosis in 4 studies

Fidexaban: structure in first source

Research Excerpts

ExcerptRelevanceReference
" To determine whether this reflects differences in the extent of vascular injury, we compared the dose-response of ZK-807834 for inhibition of venous thrombosis induced with a cotton thread and copper wire device in the presence and absence of balloon catheter-induced injury to the vena cava in rabbits."1.32Effect of vascular injury on inhibition of venous thrombosis with ZK-807834, a direct inhibitor of factor Xa. ( Abendschein, DR; Baum, PK; Light, DR; Morser, J, 2003)
" However, five of six animals given the lowest effective dosage of rTAP and four of six animals given DX-9065a bled from a surgical incision >5 min, but only two of six animals given ZK-807834 bled >5 min."1.31Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits. ( Abendschein, DR; Baum, PK; Eisenberg, PR; Light, DR; Martin, DJ; Post, J; Rumennik, G; Sullivan, ME; Vergona, R, 2000)
"The time to formation of an occlusive thrombus in the femoral arteries averaged 69+/-5 min in the control group compared to 127+/-19, 192+/-33 and 219+/-15 min in the low-, mid- and high-dose CI-1031 groups."1.31The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis. ( Hicks, GW; Janiczek-Dolphin, N; Juneau, PL; Leadley, R; McClanahan, TB; Mertz, TE; Morrison, AL; Morser, J; Peng, YW; Sullivan, ME, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abendschein, DR2
Baum, PK2
Light, DR2
Morser, J2
Martin, DJ1
Vergona, R1
Post, J1
Rumennik, G1
Sullivan, ME2
Eisenberg, PR1
McClanahan, TB1
Hicks, GW1
Morrison, AL1
Peng, YW1
Janiczek-Dolphin, N1
Mertz, TE2
Juneau, PL2
Leadley, R2
Chi, L1
Pen, YW1
Potoczak, R1
Gibson, G1
Hicks, G1
Janiczek, N1
Gallagher, K1

Other Studies

4 other studies available for fidexaban and Deep Vein Thrombosis

ArticleYear
Effect of vascular injury on inhibition of venous thrombosis with ZK-807834, a direct inhibitor of factor Xa.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:9

    Topics: Amidines; Animals; Blood Coagulation Tests; Catheterization; Dose-Response Relationship, Drug; Endot

2003
Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:5

    Topics: Amidines; Animals; Anticoagulants; Antithrombin III; Arthropod Proteins; Coronary Thrombosis; Diseas

2000
The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis.
    European journal of pharmacology, 2001, Dec-07, Volume: 432, Issue:2-3

    Topics: Amidines; Animals; Anticoagulants; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; E

2001
Assessment of ex vivo pharmacodynamic markers during inhibition of thrombosis by CI-1031 (ZK-807834), a novel direct factor Xa inhibitor.
    Pharmacology, 2002, Volume: 64, Issue:2

    Topics: Amidines; Animals; Anticoagulants; Biomarkers; Blood Coagulation; Disease Models, Animal; Dose-Respo

2002