fidexaban has been researched along with Deep Vein Thrombosis in 4 studies
Fidexaban: structure in first source
Excerpt | Relevance | Reference |
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" To determine whether this reflects differences in the extent of vascular injury, we compared the dose-response of ZK-807834 for inhibition of venous thrombosis induced with a cotton thread and copper wire device in the presence and absence of balloon catheter-induced injury to the vena cava in rabbits." | 1.32 | Effect of vascular injury on inhibition of venous thrombosis with ZK-807834, a direct inhibitor of factor Xa. ( Abendschein, DR; Baum, PK; Light, DR; Morser, J, 2003) |
" However, five of six animals given the lowest effective dosage of rTAP and four of six animals given DX-9065a bled from a surgical incision >5 min, but only two of six animals given ZK-807834 bled >5 min." | 1.31 | Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits. ( Abendschein, DR; Baum, PK; Eisenberg, PR; Light, DR; Martin, DJ; Post, J; Rumennik, G; Sullivan, ME; Vergona, R, 2000) |
"The time to formation of an occlusive thrombus in the femoral arteries averaged 69+/-5 min in the control group compared to 127+/-19, 192+/-33 and 219+/-15 min in the low-, mid- and high-dose CI-1031 groups." | 1.31 | The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis. ( Hicks, GW; Janiczek-Dolphin, N; Juneau, PL; Leadley, R; McClanahan, TB; Mertz, TE; Morrison, AL; Morser, J; Peng, YW; Sullivan, ME, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abendschein, DR | 2 |
Baum, PK | 2 |
Light, DR | 2 |
Morser, J | 2 |
Martin, DJ | 1 |
Vergona, R | 1 |
Post, J | 1 |
Rumennik, G | 1 |
Sullivan, ME | 2 |
Eisenberg, PR | 1 |
McClanahan, TB | 1 |
Hicks, GW | 1 |
Morrison, AL | 1 |
Peng, YW | 1 |
Janiczek-Dolphin, N | 1 |
Mertz, TE | 2 |
Juneau, PL | 2 |
Leadley, R | 2 |
Chi, L | 1 |
Pen, YW | 1 |
Potoczak, R | 1 |
Gibson, G | 1 |
Hicks, G | 1 |
Janiczek, N | 1 |
Gallagher, K | 1 |
4 other studies available for fidexaban and Deep Vein Thrombosis
Article | Year |
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Effect of vascular injury on inhibition of venous thrombosis with ZK-807834, a direct inhibitor of factor Xa.
Topics: Amidines; Animals; Blood Coagulation Tests; Catheterization; Dose-Response Relationship, Drug; Endot | 2003 |
Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits.
Topics: Amidines; Animals; Anticoagulants; Antithrombin III; Arthropod Proteins; Coronary Thrombosis; Diseas | 2000 |
The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis.
Topics: Amidines; Animals; Anticoagulants; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; E | 2001 |
Assessment of ex vivo pharmacodynamic markers during inhibition of thrombosis by CI-1031 (ZK-807834), a novel direct factor Xa inhibitor.
Topics: Amidines; Animals; Anticoagulants; Biomarkers; Blood Coagulation; Disease Models, Animal; Dose-Respo | 2002 |