Page last updated: 2024-10-31

fidexaban and Blood Clot

fidexaban has been researched along with Blood Clot in 4 studies

Fidexaban: structure in first source

Research Excerpts

ExcerptRelevanceReference
"Arterial thrombus formation was measured in Badimon Chamber at baseline, end-of-infusion [EoI], and four hours and eight hours after EoI, and factor-X activity, prothrombin time [PT] ratio and plasma drug levels were measured simultaneously."2.73Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients. ( Chesebro, JH; Crook, J; Farkouh, ME; Fuster, V; Leadley, R; Osende, J; Palencia, S; Shimbo, D; Zafar, MU, 2007)
"The time to formation of an occlusive thrombus in the femoral arteries averaged 69+/-5 min in the control group compared to 127+/-19, 192+/-33 and 219+/-15 min in the low-, mid- and high-dose CI-1031 groups."1.31The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis. ( Hicks, GW; Janiczek-Dolphin, N; Juneau, PL; Leadley, R; McClanahan, TB; Mertz, TE; Morrison, AL; Morser, J; Peng, YW; Sullivan, ME, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pinto, DJ1
Smallheer, JM1
Cheney, DL1
Knabb, RM1
Wexler, RR1
Karnicki, K1
McBane, RD1
Miller, RS1
Leadley, RJ1
Morser, J2
Owen, WG1
Chesebro, JH2
Zafar, MU1
Farkouh, ME1
Osende, J1
Shimbo, D1
Palencia, S1
Crook, J1
Leadley, R2
Fuster, V1
McClanahan, TB1
Hicks, GW1
Morrison, AL1
Peng, YW1
Janiczek-Dolphin, N1
Mertz, TE1
Sullivan, ME1
Juneau, PL1

Reviews

1 review available for fidexaban and Blood Clot

ArticleYear
Factor Xa inhibitors: next-generation antithrombotic agents.
    Journal of medicinal chemistry, 2010, Sep-09, Volume: 53, Issue:17

    Topics: Administration, Oral; Animals; Anticoagulants; Biological Availability; Clinical Trials as Topic; Dr

2010

Trials

1 trial available for fidexaban and Blood Clot

ArticleYear
Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:3

    Topics: Amidines; Animals; Aorta; Blood Coagulation; Coronary Artery Disease; Dose-Response Relationship, Dr

2007

Other Studies

2 other studies available for fidexaban and Blood Clot

ArticleYear
Inhibition and reversal of platelet-rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:12

    Topics: Amidines; Animals; Anticoagulants; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Dos

2004
The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis.
    European journal of pharmacology, 2001, Dec-07, Volume: 432, Issue:2-3

    Topics: Amidines; Animals; Anticoagulants; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; E

2001