Page last updated: 2024-09-04

fidarestat and Diabetes Mellitus

fidarestat has been researched along with Diabetes Mellitus in 3 studies

*Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. [MeSH]

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Demopoulos, VJ; Nicolaou, I	1
El-Kabbani, O; Podjarny, A	1
Aoki, T; Makino, M; Mizuno, K; Sassa, H; Sobajima, H; Suzuki, T; Taniko, K	1

Reviews

1 review(s) available for fidarestat and Diabetes Mellitus

Article	Year
Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites. Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:15 Topics: Aldehyde Reductase; Amino Acid Substitution; Animals; Catalytic Domain; Diabetes Mellitus; Enzyme Inhibitors; Glucose; Humans; Imidazolidines; In Vitro Techniques; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins	2007

Article

Year

Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites.

Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:15

Topics: Aldehyde Reductase; Amino Acid Substitution; Animals; Catalytic Domain; Diabetes Mellitus; Enzyme Inhibitors; Glucose; Humans; Imidazolidines; In Vitro Techniques; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins

2007

Other Studies

2 other study(ies) available for fidarestat and Diabetes Mellitus

Article	Year
Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides. Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3 Topics: Acetates; Aldehyde Reductase; Animals; Diabetes Mellitus; Enzyme Inhibitors; Female; Fructose; Male; Monosaccharides; Oxidation-Reduction; Proteins; Pyrroles; Rats; Rats, Inbred F344; Serum Albumin; Structure-Activity Relationship	2003
Pharmacological properties of fidarestat, a potent aldose reductase inhibitor, clarified by using sorbitol in human and rat erythrocytes. Pharmacology, 2001, Volume: 62, Issue:4 Topics: Age Factors; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Fasting; Female; Glycated Hemoglobin; Humans; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Rhodanine; Sciatic Nerve; Sex Factors; Sorbitol; Thiazolidines	2001

Article

Year

Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides.

Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3

Topics: Acetates; Aldehyde Reductase; Animals; Diabetes Mellitus; Enzyme Inhibitors; Female; Fructose; Male; Monosaccharides; Oxidation-Reduction; Proteins; Pyrroles; Rats; Rats, Inbred F344; Serum Albumin; Structure-Activity Relationship

2003

Pharmacological properties of fidarestat, a potent aldose reductase inhibitor, clarified by using sorbitol in human and rat erythrocytes.

Pharmacology, 2001, Volume: 62, Issue:4

Topics: Age Factors; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Fasting; Female; Glycated Hemoglobin; Humans; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Rhodanine; Sciatic Nerve; Sex Factors; Sorbitol; Thiazolidines

2001