fidarestat has been researched along with Cancer of Colon in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awasthi, S; Pal, PB; Ramana, KV; Sonowal, H; Srivastava, SK; Wen, JJ | 1 |
| Ramana, KV; Saxena, A; Srivastava, SK; Tammali, R | 2 |
| Ramana, KV; Saxena, A; Shukla, K; Sonowal, H; Srivastava, SK | 1 |
| Ramana, KV; Saxena, A; Shoeb, M; Srivastava, SK | 1 |
| Ramana, KV; Saxena, A; Shoeb, M; Srivastava, SK; Tammali, R | 1 |
| Awasthi, S; Evers, BM; Qiu, S; Ramana, KV; Reddy, AB; Rychahou, PG; Saxena, A; Srivastava, SK; Tammali, R | 1 |
7 other study(ies) available for fidarestat and Cancer of Colon
| Article | Year |
|---|---|
Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity.
Topics: Aldehyde Reductase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cardiotoxicity; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Imidazolidines; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Xenograft Model Antitumor Assays | 2017 |
Aldose Reductase Inhibitor, Fidarestat Prevents High-fat Diet-induced Intestinal Polyps in Apc
Topics: Adenomatous Polyposis Coli Protein; Aldehyde Reductase; Animals; Colonic Neoplasms; Diet, High-Fat; Enzyme Inhibitors; Female; Imidazolidines; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL | 2018 |
Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells.
Topics: Aldehyde Reductase; AMP-Activated Protein Kinase Kinases; Animals; Cell Line, Tumor; Colonic Neoplasms; HCT116 Cells; Heme Oxygenase-1; HT29 Cells; Humans; Imidazolidines; Mice; Mice, Nude; Mitochondria; NF-E2-Related Factor 2; Organelle Biogenesis; Oxidative Stress; Protein Kinases; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression.
Topics: Aldehyde Reductase; Animals; Apoptosis Regulatory Proteins; Caco-2 Cells; Cell Death; Cell Survival; Colonic Neoplasms; HT29 Cells; Humans; Imidazolidines; Immunohistochemistry; Mice; Mice, Nude; MicroRNAs; Phosphorylation; RNA-Binding Proteins; Signal Transduction; Transfection; Xenograft Model Antitumor Assays | 2013 |
Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
Topics: Aldehyde Reductase; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; HT29 Cells; Humans; Imidazolidines; Inflammation Mediators; Intestinal Mucosa; Male; Mice, Inbred C57BL; Obesity; Oxidative Stress; Precancerous Conditions; Signal Transduction | 2014 |
Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
Topics: Aldehyde Reductase; Caco-2 Cells; Cell Hypoxia; Colonic Neoplasms; Cyclooxygenase 2; Cysteine Proteinase Inhibitors; Dinoprostone; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazolidines; Leupeptins; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein-Lysine 6-Oxidase; Proto-Oncogene Proteins c-akt; RNA, Messenger; RNA, Neoplasm; Vascular Endothelial Growth Factor A; Vimentin | 2011 |
Inhibition of aldose reductase prevents colon cancer metastasis.
Topics: Aldehyde Reductase; Animals; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Colonic Neoplasms; Humans; Imidazolidines; Immunoenzyme Techniques; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering | 2011 |