fibrinopeptide-a and Graves-Disease

fibrinopeptide-a has been researched along with Graves-Disease* in 2 studies

Other Studies

2 other study(ies) available for fibrinopeptide-a and Graves-Disease

ArticleYear
Activation of blood coagulation and fibrinolysis in Graves' disease.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:12

    We studied blood coagulation and fibrinolysis activities in hyperthyroidism before and after methimazole or 131I. Fibrinopeptide A and B beta 15-42, in vivo indicators of thrombin and plasmin activity, were measured by RIA, while fibrinogen by the Clauss method. We studied 50 patients, affected by toxic diffuse goiter. We evaluated 21 of them before and after treatment. Fibrinogen, fibrinopeptide A, and B beta 15-42 were higher in patients than in controls (p less than 0.0001). There was no difference in fibrinopeptide A nor in B beta 15-42 before or after treatment. In euthyroidism fibrinogen returned to normal values. Inflammation of the thyroid gland secondary to autoimmunity may activate blood coagulation by release of tissue factor. High fibrinogen before treatment may be explained as an aspecific response. Since it persists in euthyroidism, autoimmunity could account for high fibrinopeptide A and B beta 15-42 aftertreatment.

    Topics: Adolescent; Adult; Aged; Blood Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Fibrinopeptide A; Fibrinopeptide B; Graves Disease; Humans; Iodine Radioisotopes; Male; Methimazole; Middle Aged; Peptide Fragments

1991
Anticardiolipin antibodies in Grave's disease: relationship with thrombin activity in vivo.
    Thrombosis research, 1991, Dec-15, Volume: 64, Issue:6

    Topics: Adult; Autoantibodies; Cardiolipins; Female; Fibrinopeptide A; Graves Disease; Humans; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged; Thrombin

1991