Page last updated: 2024-08-26

fibrinogen and Acute Confusional Senile Dementia

fibrinogen has been researched along with Acute Confusional Senile Dementia in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (6.90)18.2507
2000's9 (15.52)29.6817
2010's32 (55.17)24.3611
2020's13 (22.41)2.80

Authors

AuthorsStudies
Bhattacharjee, S; Bhattacharyya, R1
Baruah, P; Doshi, J; Mitra, S; Paul, D1
Arboleda-Velasquez, JF; Drexler, D; Glatzel, M; Hagel, C; Hase, Y; Kalaria, R; Krasemann, S; Littau, JL; Lopera, F; Osorio Restrepo, S; Quiroz, YT; Sepulveda-Falla, D; Vargas, S; Velilla, L; Villalba-Moreno, ND; Villegas, A1
Akassoglou, K; Merlini, M; Nana, AL; Seeley, WW; Sozmen, EG; Subramanian, KS1
Agrawal, A; Akassoglou, K; Alzamora, MDPS; Arun, N; Bouhaddou, M; Cabriga, B; Dixit, K; Johnson, JR; Krogan, NJ; MacDonald, E; Mendiola, AS; Meyer-Franke, A; Meza-Acevedo, R; Muthukumar, G; Pearce, C; Pico, AR; Ryu, JK; Shin, MG; Yan, Z; Yong, Y; Zamvil, SS1
Bian, Y; Bian, Z; Fukui, Y; Hu, X; Ishiura, H; Liu, X; Morihara, R; Sun, H; Yamashita, T; Yu, H1
Akassoglou, K; Kantor, AB; Stavenhagen, JB1
Li, Q; Liu, W; Sun, Y; Zhang, B1
Barroso, R; Burleigh, A; Donner, L; Elvers, M; Gerdes, N; Gröniger, S; Kelm, M; Krüger, I; Mezzano, D; Pfeiler, S; Sun, Y; Toska, LM; Watson, SP1
Dounavi, ME; Low, A; Mak, E; Markus, HS; Muniz-Terrera, G; O'Brien, JT; Ritchie, CW; Ritchie, K; Stefaniak, JD; Su, L1
Choi, SH; Hong, CH; Hong, JY; Hwangbo, S; Jang, H; Jang, JW; Jeong, JH; Jung, NY; Jung, SH; Kang, SH; Kim, B; Kim, BC; Kim, EJ; Kim, HJ; Kim, HR; Kim, J; Kim, JP; Kim, KW; Kim, S; Kim, SE; Kim, SY; Lee, J; Lee, JS; Na, DL; Noh, Y; Park, KW; Seo, SW; Son, SJ; Won, HH; Yoon, B; Yoon, SJ1
Abe, K; Bian, Y; Bian, Z; Feng, T; Hu, X; Morihara, R; Omote, Y; Shi, X; Sun, H; Tadokoro, K; Takemoto, M; Yamashita, T; Yu, H1
Akassoglou, K; Davalos, D; Merlini, M; Schuck, R; Tognatta, R; Yan, Z1
Ahn, HJ; Chen, ZL; Norris, EH; Strickland, S; Zamolodchikov, D1
Garg, VK; Goyal, MK; Lal, V; Mittal, BR; Modi, M; Mohanty, M; Prabhakar, S; Vishnu, VY1
Fujii, N; Ha, S; Isoyama, M; Kim, I; Kinouchi, T; Suzuki, M; Takata, T1
Ahn, HJ; Aso, K; Berk-Rauch, HE; Foley, MA; Kawasaki, M; Nishida, G; Norris, EH; Singh, PK; Strickland, S; Yamasaki, T1
Attems, J; DeCarli, C; Dey, M; Erskine, D; Graham, S; Johnson, M; Johnston, E; McAleese, KE; McKeith, IG; Thomas, AJ; Walker, L1
Akassoglou, K; Davalos, D; Ellisman, M; Gill, TM; Merlini, M; Mucke, L; Muthukumar, G; Nelson, RB; Rafalski, VA; Rios Coronado, PE; Ryu, JK; Seeley, WW; Subramanian, KS; Syme, CA1
Wood, H1
de Beer, MC; de Villiers, WJS; Engelbrecht, AM; Engelbrecht, L; Kell, DB; Nell, TA; Nunes, JM; Page, MJ; Pretorius, E; Thomson, GJA1
Ahn, HJ; Baker, SK; Norris, EH; Strickland, S1
Hultman, K; Norris, EH; Strickland, S1
Arito, M; Iizuka, N; Kato, T; Kurokawa, MS; Nagai, K; Noguchi, M; Okamoto, K; Sato, T; Suematsu, N; Suzuki, I; Utagawa, I; Yamaguchi, N1
Gentleman, SM; Griffin, WS; Kalaitzakis, ME; Pearce, RK; Pey, P1
Ahn, HJ; Glickman, JF; Jno-Charles, OC; Norris, EH; Poon, KL; Strickland, S; Zamolodchikov, D1
Lominadze, D; Metreveli, N; Muradashvili, N; Tyagi, R; Tyagi, SC1
Flemming, A1
Cortes-Canteli, M; Mattei, L; Norris, EH; Richards, AT; Strickland, S1
Bester, J; Boyle, PK; Jacobsen, WK; Nielsen, VG; Pretorius, E; Reinhard, JP1
Curtis, MA; Dragunow, M; Faull, RL; Feng, S; Kim, SL; Lill, C; Narayan, PJ1
Chung, YC; Feierman, E; Kruyer, A; Norris, EH; Richards, A; Strickland, S; Yao, Y1
Lominadze, D; Muradashvili, N; Tyagi, N; Tyagi, R; Tyagi, SC1
Strickland, S; Zamolodchikov, D1
Donner, L; Elvers, M; Fälker, K; Gohlke, H; Gremer, L; Grenegard, M; Klinker, S; Ljungberg, LU; Lothmann, K; Pagani, G; Rizzi, F; Schaller, M; Willbold, D1
Burrell, M; Fowler, SB; Hansson, KM; Henderson, SJ; Ravnefjord, A; Schweikart, F; Webster, CI; Witt, S1
Awala, H; Barzegari, E; Derakhshankhah, H; Dinarvand, R; Ferdousi, M; Hajipour, MJ; Lotfabadi, A; Mahmoudi, M; Mintova, S; Ng, EP; Raoufi, M; Saboury, AA1
Ichihara, S; Kida, H; Kitamura, Y; Murata, M; Oikawa, S; Satoh, M; Tomimoto, H; Usami, R1
McLarnon, JG; Ryu, JK1
Cortes-Canteli, M; Strickland, S1
Ahn, HJ; Bhuvanendran, S; Bronstein, R; Cortes-Canteli, M; Fenz, KM; Norris, EH; Paul, J; Strickland, S; Zamolodchikov, D1
Ahn, HJ; Cortes-Canteli, M; Glickman, JF; Norris, EH; Strickland, S; Zamolodchikov, D1
Benítez-Herreros, J; Cañones-Zafra, R; Jiménez-Parras, R; Kubiak, K; Montes-Mollón, MA1
Akassoglou, K; Davalos, D1
Ball, G; Boocock, D; Coveney, C; Hansson, O; Janciauskiene, SM; Kalsheker, N; Lemetre, C; Matharoo-Ball, B; Miles, AK; Minthon, L; Morgan, K; Rees, R; Smith, AD; Vafadar-Isfahani, B; Warden, D; Wilcock, G1
Buller, C; Järemo, P; Milovanovic, M; Nilsson, S; Winblad, B1
Ahn, HJ; Cortes-Canteli, M; Norris, EH; Strickland, S; Zamolodchikov, D1
Gupta, A; Habubi, N; Majer, R; Morris, G; Pansari, K; Thomas, P; Watkins, A1
Cullen, KM; Kócsi, Z; Stone, J1
Breteler, MM; Hofman, A; Koudstaal, PJ; van Oijen, M; Witteman, JC1
Ha, SA; Hwang, DW; Kim, HK; Kim, JR; Kim, JW; Kim, S; Lee, JW; Na, HR; Namkoong, H1
Melchor, JP; Paul, J; Strickland, S1
Chen, X; Gawryluk, JW; Geiger, JD; Ghribi, O; Wagener, JF1
Badellino, K; Kowalska, MA1
Bottasso, B; Coppola, R; Mannucci, PM; Mari, D; Parnetti, L; Reboldi, GP; Senin, U1
Ahn, YS; Horstman, LL; Jy, W; Kolodny, L; Mao, WW; Sevush, S1
Rogers, J; Shen, Y; Strohmeyer, R1
Lee, VM; Stern, RA; Trojanowski, JQ1

Reviews

6 review(s) available for fibrinogen and Acute Confusional Senile Dementia

ArticleYear
Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population.
    Alzheimer's research & therapy, 2021, 06-21, Volume: 13, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Fibrinogen; Genome-Wide Association Study; Humans; Positron-Emission Tomography; Republic of Korea

2021
Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease.
    Current opinion in hematology, 2017, Volume: 24, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Factor XII; Fibrinogen; Humans

2017
A possible new role for Aβ in vascular and inflammatory dysfunction in Alzheimer's disease.
    Thrombosis research, 2016, Volume: 141 Suppl 2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Coagulation; Factor XII; Fibrinogen; Humans; Inflammation

2016
Fibrinogen, a possible key player in Alzheimer's disease.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7 Suppl 1

    Topics: Alzheimer Disease; Cerebrovascular Disorders; Fibrinogen; Humans; Inflammation

2009
Fibrinogen as a key regulator of inflammation in disease.
    Seminars in immunopathology, 2012, Volume: 34, Issue:1

    Topics: Alzheimer Disease; Animals; Arthritis, Rheumatoid; Bacterial Infections; Blood Coagulation; Brain Injuries; Colitis; Fibrinogen; Humans; Inflammation; Kidney Diseases; Multiple Sclerosis; Muscular Dystrophy, Duchenne; Neoplasms; Pulmonary Fibrosis; Spinal Cord Injuries; Stroke; Thrombin; Thromboplastin; Vascular Diseases

2012
Fibrinogen and altered hemostasis in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 32, Issue:3

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cerebrovascular Circulation; Fibrinogen; Hemostasis; Humans

2012

Trials

1 trial(s) available for fibrinogen and Acute Confusional Senile Dementia

ArticleYear
Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.
    Stroke, 2005, Volume: 36, Issue:12

    Topics: Aged; Alzheimer Disease; C-Reactive Protein; Cohort Studies; Dementia, Vascular; Female; Fibrinogen; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies

2005

Other Studies

51 other study(ies) available for fibrinogen and Acute Confusional Senile Dementia

ArticleYear
PRFF Peptide Mimic Interferes with Toxic Fibrin-Aβ
    ACS chemical neuroscience, 2021, 11-03, Volume: 12, Issue:21

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Fibrin; Fibrinogen; Fibrinolysin; Humans; Peptide Fragments

2021
Elevated Fibrinogen Level Reduces Therapeutic Efficiency of AD Drugs: Biophysical Insights into the Interaction of FDA-Approved Cholinesterase Inhibitors with Human Fibrinogen.
    The journal of physical chemistry. B, 2022, 01-13, Volume: 126, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Fibrinogen; Humans; Pharmaceutical Preparations; Tacrine

2022
Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease.
    Brain pathology (Zurich, Switzerland), 2022, Volume: 32, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; CADASIL; Fibrinogen; Humans

2022
Three-Dimensional Imaging of Fibrinogen and Neurovascular Alterations in Alzheimer's Disease.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2561

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Fibrinogen; Humans; Imaging, Three-Dimensional; Plaque, Amyloid

2023
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling.
    Nature immunology, 2023, Volume: 24, Issue:7

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Fibrinogen; Mice; Microglia; Multiomics

2023
Protective Effects of Rivaroxaban on White Matter Integrity and Remyelination in a Mouse Model of Alzheimer's Disease Combined with Cerebral Hypoperfusion.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 96, Issue:2

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Disease Models, Animal; Fibrinogen; Humans; Mice; Remyelination; Rivaroxaban; White Matter

2023
Fibrin-Targeting Immunotherapy for Dementia.
    The journal of prevention of Alzheimer's disease, 2023, Volume: 10, Issue:4

    Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Epitopes; Fibrin; Fibrinogen; Humans; Immunotherapy; Mice; Neurodegenerative Diseases; Thrombin

2023
Relationship between fibrinogen level and its regulatory gene with Alzheimer's disease and vascular dementia.
    The Journal of international medical research, 2020, Volume: 48, Issue:2

    Topics: Alzheimer Disease; Dementia, Vascular; Fibrinogen; Genes, Regulator; Genetic Predisposition to Disease; Humans

2020
The collagen receptor glycoprotein VI promotes platelet-mediated aggregation of β-amyloid.
    Science signaling, 2020, 08-04, Volume: 13, Issue:643

    Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Platelets; Cells, Cultured; Fibrinogen; Humans; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein Aggregation, Pathological; Protein Binding; Receptors, Collagen; Signal Transduction

2020
Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study.
    Neurobiology of aging, 2021, Volume: 98

    Topics: Alzheimer Disease; Apolipoprotein E4; Biomarkers; C-Reactive Protein; Cerebral Small Vessel Diseases; Cognition; Dementia; Disease Progression; Female; Fibrinogen; Genetic Association Studies; Genetic Predisposition to Disease; Healthy Aging; Heterozygote; Humans; Inflammasomes; Male; Middle Aged; Risk; White Matter

2021
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains.
    Brain research, 2021, 09-15, Volume: 1767

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Fibrinogen; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Peptides

2021
    STAR protocols, 2021, 09-17, Volume: 2, Issue:3

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Brain; Dendritic Spines; Disease Models, Animal; Fibrinogen; Fluorescent Dyes; Mice; Microglia; Microscopy; Photons

2021
Role of inflammatory and hemostatic biomarkers in Alzheimer's and vascular dementia - A pilot study from a tertiary center in Northern India.
    Asian journal of psychiatry, 2017, Volume: 29

    Topics: Alzheimer Disease; Biomarkers; Brain; C-Reactive Protein; Dementia, Vascular; Diagnosis, Differential; Disease Progression; Fibrinogen; Humans; India; Interleukin-6; Magnetic Resonance Imaging; Pilot Projects; Positron-Emission Tomography; Sensitivity and Specificity

2017
Identification of ᴅ-amino acid-containing peptides in human serum.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Adult; Alzheimer Disease; Amino Acids; Aspartic Acid; Biomarkers; Cataract; Chromatography, Liquid; Crystallins; Fibrinogen; Fibrinopeptide B; Humans; Middle Aged; Peptides; Proteomics; Tandem Mass Spectrometry; Young Adult

2017
Aminopyrimidine Class Aggregation Inhibitor Effectively Blocks Aβ-Fibrinogen Interaction and Aβ-Induced Contact System Activation.
    Biochemistry, 2018, 02-27, Volume: 57, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Drug Design; Fibrinogen; Humans; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Interaction Maps; Pyrimidines

2018
Extravascular fibrinogen in the white matter of Alzheimer's disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer's disease.
    Brain pathology (Zurich, Switzerland), 2019, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arteriolosclerosis; Biomarkers; Blood-Brain Barrier; Brain; Cerebral Amyloid Angiopathy; Cerebral Small Vessel Diseases; Female; Fibrinogen; Humans; Leukoencephalopathies; Male; Middle Aged; Plaque, Amyloid; tau Proteins; White Matter

2019
Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
    Neuron, 2019, 03-20, Volume: 101, Issue:6

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Brain; CD11b Antigen; CD18 Antigens; Cognitive Dysfunction; Dendritic Spines; Disease Models, Animal; Fibrinogen; Humans; Imaging, Three-Dimensional; Mice; Microglia; Plaque, Amyloid; Reactive Oxygen Species

2019
Fibrinogen links vascular pathology to cognitive decline.
    Nature reviews. Neurology, 2019, Volume: 15, Issue:4

    Topics: Alzheimer Disease; Cognitive Dysfunction; Fibrinogen; Humans; Microglia; Neuropsychological Tests

2019
Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation.
    Scientific reports, 2019, 02-28, Volume: 9, Issue:1

    Topics: Acute-Phase Reaction; Adult; Agglutination; Alzheimer Disease; Amyloid; Blood Coagulation; Blood Platelets; Female; Fibrinogen; Humans; Middle Aged; Platelet Activation; Platelet Aggregation; Protein Binding; Serum Amyloid A Protein; Thrombosis

2019
Inflaming the Brain.
    Neuron, 2019, 03-20, Volume: 101, Issue:6

    Topics: Alzheimer Disease; Brain; Cognitive Dysfunction; Fibrinogen; Humans; Microglia

2019
The APOE ɛ4/ɛ4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apolipoprotein E4; Atherosclerosis; Blood Vessels; Brain; Cerebral Amyloid Angiopathy; Disease Progression; Female; Fibrinogen; Genotype; Humans; Immunohistochemistry; Male; Middle Aged; Plaque, Amyloid; Sex Characteristics

2013
Roles of serum fibrinogen α chain-derived peptides in Alzheimer's disease.
    International journal of geriatric psychiatry, 2014, Volume: 29, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Male; Mass Spectrometry; Middle Aged; Peptide Fragments; ROC Curve; Sensitivity and Specificity

2014
Phenotypic profile of alternative activation marker CD163 is different in Alzheimer's and Parkinson's disease.
    Acta neuropathologica communications, 2014, Feb-14, Volume: 2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain; Calcium-Binding Proteins; Cell Count; DNA-Binding Proteins; Female; Fibrinogen; Humans; Macrophages; Male; Membrane Glycoproteins; Microfilament Proteins; Microglia; Middle Aged; Neurologic Examination; Parkinson Disease; Plaque, Amyloid; Receptors, Cell Surface; Receptors, Immunologic

2014
A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice.
    The Journal of experimental medicine, 2014, Jun-02, Volume: 211, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibrinogen; Humans; Maze Learning; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Molecular Structure; Motor Activity; Protein Binding; Pyrazoles; Pyrimidines; Small Molecule Libraries; Thrombosis; Time-Lapse Imaging

2014
Ablation of MMP9 gene ameliorates paracellular permeability and fibrinogen-amyloid beta complex formation during hyperhomocysteinemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:9

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antigens, CD; Cadherins; Capillary Permeability; Cerebrovascular Circulation; Cystathionine beta-Synthase; Enzyme Activation; Fibrinogen; Gene Expression Regulation; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Memory, Short-Term; Mice; Mice, Knockout; Multiprotein Complexes

2014
Alzheimer's disease: Aβ-fibrinogen interaction inhibitor improves cognition in AD.
    Nature reviews. Drug discovery, 2014, Volume: 13, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition Disorders; Fibrinogen; Humans; Pyrazoles; Pyrimidines; Small Molecule Libraries; Thrombosis

2014
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration.
    Neurobiology of aging, 2015, Volume: 36, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Brain; Fibrin; Fibrinogen; Humans; Inflammation; Intracranial Thrombosis; Memory Disorders; Mice, Transgenic; Molecular Targeted Therapy; Nerve Degeneration; Neurites; Neurons

2015
Carbon monoxide and iron modulate plasmatic coagulation in Alzheimer's disease.
    Current neurovascular research, 2015, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Coagulation; Carbon Monoxide; Cohort Studies; Female; Ferritins; Fibrinogen; Humans; Iron; Male; Microscopy, Electron, Scanning; Middle Aged; Plasma; Radionuclide Imaging; Thrombin

2015
Assessing fibrinogen extravasation into Alzheimer's disease brain using high-content screening of brain tissue microarrays.
    Journal of neuroscience methods, 2015, May-30, Volume: 247

    Topics: Aged; Alzheimer Disease; Brain; Female; Fibrinogen; Humans; Image Processing, Computer-Assisted; Male; Tissue Array Analysis

2015
Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biotinylation; Brain; Cerebral Amyloid Angiopathy; Dementia, Vascular; Disease Models, Animal; Disease Progression; Fibrin; Fibrinogen; Fibrinolysis; Humans; Hyperhomocysteinemia; Immunohistochemistry; Maze Learning; Memory; Methionine; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Binding

2016
Cerebrovascular disorders caused by hyperfibrinogenaemia.
    The Journal of physiology, 2016, 10-15, Volume: 594, Issue:20

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caveolae; Caveolin 1; Cerebrovascular Circulation; Cerebrovascular Disorders; Fibrinogen; Memory, Short-Term; Mice; Mice, Inbred C57BL; Permeability

2016
Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.
    Science signaling, 2016, 05-24, Volume: 9, Issue:429

    Topics: Adolescent; Adult; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Platelets; Brain; Cerebrovascular Circulation; Clusterin; Crosses, Genetic; Disease Progression; Female; Fibrinogen; Genotype; Humans; Integrin alpha2; Integrins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Molecular Dynamics Simulation; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Signal Transduction; Young Adult

2016
Neprilysin Inhibits Coagulation through Proteolytic Inactivation of Fibrinogen.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Coagulation; Cerebral Amyloid Angiopathy; Fibrin; Fibrinogen; Humans; Macaca fascicularis; Neprilysin; Partial Thromboplastin Time; Proteolysis; Prothrombin Time; Rats; Serum Albumin; Thromboplastin

2016
Zeolite Nanoparticles Inhibit Aβ-Fibrinogen Interaction and Formation of a Consequent Abnormal Structural Clot.
    ACS applied materials & interfaces, 2016, Nov-16, Volume: 8, Issue:45

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Fibrinogen; Humans; Metal Nanoparticles; Zeolites

2016
Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease.
    Neurological research, 2017, Volume: 39, Issue:3

    Topics: Aged; Aged, 80 and over; alpha-2-HS-Glycoprotein; Alzheimer Disease; Apolipoprotein A-I; Apolipoproteins A; Biomarkers; Blood Proteins; Carrier Proteins; Early Diagnosis; Female; Fibrinogen; Glycoproteins; Humans; Male; Middle Aged; Peptide Fragments; Proteomics; Serum Albumin; Serum Albumin, Human; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Two-Dimensional Difference Gel Electrophoresis

2017
A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9A

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Ancrod; Animals; Astrocytes; Blood Vessels; Blood-Brain Barrier; Brain; Dementia; Fibrinogen; Fluorescence; Humans; Inflammation; Macrophage-1 Antigen; Male; Microglia; Middle Aged; Peptide Fragments; Permeability; Rats; Rats, Sprague-Dawley; von Willebrand Factor

2009
Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease.
    Neuron, 2010, Jun-10, Volume: 66, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Coagulation; Fibrinogen; Fibrinolysis; Humans; Intracranial Thrombosis; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Peptide Fragments; Protein Binding

2010
Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Dec-14, Volume: 107, Issue:50

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Blood Vessels; Fibrin; Fibrinogen; Humans; Mice; Protein Binding; Protein Structure, Quaternary

2010
[Sterile non-traumatic corneal perforation treated with Tachosil®].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:8

    Topics: Absorbable Implants; Aged, 80 and over; Alzheimer Disease; Antibiotic Prophylaxis; Contact Lenses; Corneal Perforation; Corneal Ulcer; Drug Combinations; Fibrinogen; Humans; Male; Medroxyprogesterone; Mydriatics; Surgical Sponges; Thrombin

2011
Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 28, Issue:3

    Topics: Algorithms; Alzheimer Disease; Amyloid beta-Peptides; Area Under Curve; Biomarkers; Calcium-Binding Proteins; Case-Control Studies; Cognitive Dysfunction; Cohort Studies; Computational Biology; Cytoskeleton; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix Proteins; Female; Fibrinogen; Humans; Male; Neural Networks, Computer; Peptide Fragments; Peptide Mapping; Proteomics; Psychiatric Status Rating Scales; ROC Curve; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tau Proteins

2012
Low-density platelet populations demonstrate low in vivo activity in sporadic Alzheimer disease.
    Platelets, 2012, Volume: 23, Issue:2

    Topics: Aged; Alzheimer Disease; Blood Platelets; Case-Control Studies; Female; Fibrinogen; Humans; Male; Platelet Activation

2012
Coagulation and inflammatory markers in Alzheimer's and vascular dementia.
    International journal of clinical practice, 2005, Volume: 59, Issue:1

    Topics: Alzheimer Disease; Analysis of Variance; Biomarkers; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulation Tests; Case-Control Studies; Dementia, Vascular; Fibrinogen; Humans; Inflammation; Risk Factors

2005
Pericapillary haem-rich deposits: evidence for microhaemorrhages in aging human cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Capillaries; Cerebral Cortex; Cerebral Hemorrhage; Collagen Type IV; Dementia, Vascular; Erythrocytes; Factor VIII; Female; Fibrinogen; Heme; Humans; Male; Middle Aged

2005
Fibrinogen gamma-A chain precursor in CSF: a candidate biomarker for Alzheimer's disease.
    BMC neurology, 2007, Jun-12, Volume: 7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Dementia; Female; Fibrinogen; Humans; Male

2007
Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.
    The Journal of experimental medicine, 2007, Aug-06, Volume: 204, Issue:8

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Disease Models, Animal; Disease Progression; Fibrin; Fibrinogen; Inflammation; Mice; Mice, Transgenic; Models, Biological; Permeability; Plasminogen; Tranexamic Acid

2007
Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease.
    Journal of neuroinflammation, 2008, Apr-03, Volume: 5

    Topics: Alzheimer Disease; Animals; Astrocytes; Blood-Brain Barrier; Caffeine; Central Nervous System Stimulants; Cholesterol; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinogen; Immunoglobulin G; Membrane Proteins; Microglia; Occludin; Rabbits; Random Allocation; Tight Junctions

2008
beta-Amyloid protein induces platelet aggregation and supports platelet adhesion.
    Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Binding Sites; Fibrinogen; Humans; In Vitro Techniques; Macromolecular Substances; Membrane Glycoproteins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thrombosis; Thrombospondins

1994
Hemostasis abnormalities in patients with vascular dementia and Alzheimer's disease.
    Thrombosis and haemostasis, 1996, Volume: 75, Issue:2

    Topics: Aged; Alzheimer Disease; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Proteins; Dementia, Vascular; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Fibrinopeptide A; Humans; Male; Peptide Fragments; Prothrombin

1996
Platelet activation in Alzheimer disease.
    Archives of neurology, 1998, Volume: 55, Issue:4

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Platelet Activation; Platelet Count; Platelet Factor 3

1998
Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.
    Brain research. Molecular brain research, 2000, Sep-30, Volume: 81, Issue:1-2

    Topics: Aged; Alzheimer Disease; Complement Factor B; Complement Factor H; Complement Pathway, Alternative; Complement System Proteins; Female; Fibrinogen; Frontal Lobe; Humans; Immunohistochemistry; Male; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic

2000
Antibodies to the beta-amyloid peptide cross-react with conformational epitopes in human fibrinogen subunits from peripheral blood.
    FEBS letters, 1990, May-07, Volume: 264, Issue:1

    Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Antibodies; Antibodies, Monoclonal; Blotting, Western; Brain Chemistry; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrinogen; Humans; Nerve Tissue Proteins; Pheochromocytoma; Protein Conformation; Rats

1990