fibrin and Typhoid-Fever

The plasma levels of D-dimer can be used as a marker of fibrin formation and degradation. Plasma D-dimer levels in the febrile phase of 6 patients with typhoid fever and in the afebrile convalescent phase of 4 of them were measured. D-dimer levels were high in the febrile phase of all 6 patients and within normal range in the afebrile convalescent phase of all 4 patients. Our results indicate that thrombus formation and fibrinolysis may occur in the febrile phase of patients with typhoid fever.

Topics: Adolescent; Adult; Female; Fever; Fibrin; Fibrin Fibrinogen Degradation Products; Humans; Male; Thrombosis; Typhoid Fever

Topics: Bacteria; Cell Membrane; Cell Nucleus; Child; Eosinophils; Erythrocytes; Extracellular Space; Fibrin; Golgi Apparatus; Humans; Lymph Nodes; Lymphadenitis; Lymphocytes; Macrophages; Male; Microscopy; Microscopy, Electron; Mitochondria; Monocytes; Necrosis; Phagocytosis; Typhoid Fever