fibrin and Sarcoma

fibrin has been researched along with Sarcoma* in 5 studies

Other Studies

5 other study(ies) available for fibrin and Sarcoma

ArticleYear
Pleomorphic hyalinizing angiectatic tumor with a sarcomatous component recurring as high-grade myxofibrosarcoma.
    Pathology international, 2007, Volume: 57, Issue:5

    Pleomorphic hyalinizing angiectatic tumor (PHAT) of the soft tissue is a rare distinctive tumor listed as a benign neoplasm in the new World Health Organization classification. It may recur and most reported recurrent tumors retained the typical morphological appearance of PHAT; rare tumors recurred with the appearance of a sarcoma. Reported herein is an additional example of recurrent PHAT, but in contrast to the previously described cases the present tumor morphologically qualified as a sarcoma from the very beginning; it recurred as a high-grade myxofibrosarcoma. A 76-year-old woman presented with a solitary subcutaneous tumor in the axilla that was surgically removed. Seven months later, the patient experienced a local recurrence. Microscopically, the typical features of PHAT were identified in the initial lesion, namely hyalinized, fibrin-containing vessels and pleomorphic stromal cells; there were areas of hemorrhage and necrosis. Additionally, peripherally located areas of the tumor manifested highly pleomorphic cells with frequent atypical mitoses, producing a sarcomatous appearance. The mitotic index in the sarcomatous part was 1/10 high-power fields (HPF). Hyalinized, fibrin-containing vessels were absent in these sarcomatous areas, and the stroma was myxoid. The recurrent lesion was composed of large highly pleomorphic oval, round, spindled or bizarre cells with a high mitotic rate, ranging from 3/10 HPF to 7/10 HPF. The neoplastic cells were arranged haphazardly in a myxoid matrix. Hyalinized, fibrin-containing vessels typical for PHAT were absent. PHAT may be more aggressive than previously thought, and PHAT may encompass a morphological spectrum of the lesion ranging from benign to malignant.

    Topics: Aged; Dermatofibrosarcoma; Female; Fibrin; Humans; Hyalin; Necrosis; Neoplasm Recurrence, Local; Sarcoma; Skin; Skin Neoplasms

2007
Fibrin-bound tumour cells on a sclerosed mitral valve.
    Pathology, 1977, Volume: 9, Issue:3

    The association of fibrin and tumour cells on a sclerosed mitral valve in a 62-year-old woman is described. This was the first indication of malignant disease but bilateral ovarian cancer was proved two months later. ino further tumour deposits have been found in fifteen months. The tumour deposit on the valve was most likely a metastasis but primary heart valve sarcoma has not been positively excluded. If the lesion was a secondary deposit this has possible implications for the role of fibrin in metastasis in humans.

    Topics: Female; Fibrin; Heart Neoplasms; Heart Valve Diseases; Humans; Middle Aged; Mitral Valve; Neoplasm Metastasis; Neoplastic Cells, Circulating; Ovarian Neoplasms; Ovary; Sarcoma; Sclerosis

1977
[Chronic form of the course of consumption coagulopathy in sarcoma of the A. pulmonalis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Mar-15, Volume: 29, Issue:6

    Topics: Aged; Autopsy; Chronic Disease; Disseminated Intravascular Coagulation; Female; Fibrin; Fibrosarcoma; Hematoma; Hematuria; Humans; Leiomyosarcoma; Pulmonary Artery; Sarcoma; Thromboplastin

1974
[Localization of fibrin in human tumors].
    Arkhiv patologii, 1969, Volume: 31, Issue:7

    Topics: Adenocarcinoma; Adenoma; Adrenal Gland Neoplasms; Breast Diseases; Breast Neoplasms; Female; Fibrin; Fluorescent Antibody Technique; Genital Neoplasms, Female; Hodgkin Disease; Humans; Lymph Nodes; Lymphatic Diseases; Melanoma; Methods; Neoplasms; Neoplasms, Nerve Tissue; Ovarian Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Tuberculosis

1969
[Hyperfibrinemia in Hodgkin's disease and in malignant reticular gangliopathies].
    La Presse medicale, 1958, Sep-27, Volume: 66, Issue:66

    Topics: Blood Cells; Fibrin; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma

1958