fibrin and Pressure-Ulcer

fibrin has been researched along with Pressure-Ulcer* in 2 studies

Reviews

1 review(s) available for fibrin and Pressure-Ulcer

Article	Year
Recent findings on decubitus ulcer pathology: implications for care. Geriatrics, 1986, Volume: 41, Issue:1 Vasodilators are ineffective therapy for decubitus ulcers because blood vessels are absent in the necrotic areas. Systemic application of vasodilating drugs actually decreases the nutritional blood flow through the damaged zone. Protracted healing of decubitus ulcers may be explained by an altered nutrient transport rate to the cells caused by fibrin thrombi in the capillaries and fibrin deposits in the intercellular space, resulting from decreased fibrinolytic activity. Topics: Disinfectants; Fibrin; Humans; Oxygen; Posture; Pressure; Pressure Ulcer; Skin; Wound Healing	1986

Article

Year

Recent findings on decubitus ulcer pathology: implications for care.

Geriatrics, 1986, Volume: 41, Issue:1

Vasodilators are ineffective therapy for decubitus ulcers because blood vessels are absent in the necrotic areas. Systemic application of vasodilating drugs actually decreases the nutritional blood flow through the damaged zone. Protracted healing of decubitus ulcers may be explained by an altered nutrient transport rate to the cells caused by fibrin thrombi in the capillaries and fibrin deposits in the intercellular space, resulting from decreased fibrinolytic activity.

Topics: Disinfectants; Fibrin; Humans; Oxygen; Posture; Pressure; Pressure Ulcer; Skin; Wound Healing

1986

Trials

1 trial(s) available for fibrin and Pressure-Ulcer

Article	Year
Definition of efficiency in vacuum therapy--a randomised controlled trial comparing with V.A.C. Therapy. International wound journal, 2008, Volume: 5, Issue:5 Redon drains are still used to suction wounds for vacuum sealing. Vacuum-assisted closure (V.A.C.((R)); Kinetic Concepts Inc, San Antonio, TX) is a computer-controlled therapy system for delivering topical negative pressure therapy. The efficiency of V.A.C. in the treatment of pressure ulcers was prospectively studied in a randomised controlled trial in which patients with pressure ulcers were randomly assigned to negative pressure wound therapy (NPWT) using either V.A.C. or Redon bottles. The target parameters were absolute and relative proportion of wound area consists of granulation tissue, fibrin and necrosis. Other outcome measures were the number of dressing changes and time invested using each system. The study was terminated after a post hoc analysis after inclusion of ten patients because of the significantly better results when using V.A.C., and the substantially larger care effort needed in the Redon group compared with the V.A.C. group. An increase in surface granulation tissue of 54% was observed in the V.A.C. group, and a reduction in the Redon group (P = 0.001). The Redon group showed an increase in fibrin tissue at the wound base of 21.8%, whereas in the V.A.C group, a 27% reduction was observed (P = 0.035). Necrosis was reduced in the V.A.C. group, but this difference did not reach significance. Redon bottles are not a good alternative for V.A.C. therapy for delivering NPWT. Topics: Aged; Aged, 80 and over; Austria; Debridement; Drainage; Equipment Design; Equipment Failure; Fibrin; Granulation Tissue; Humans; Necrosis; Negative-Pressure Wound Therapy; Nursing Evaluation Research; Pressure Ulcer; Severity of Illness Index; Therapy, Computer-Assisted; Time and Motion Studies; Treatment Outcome; Workload; Wound Healing	2008

Article

Year

Definition of efficiency in vacuum therapy--a randomised controlled trial comparing with V.A.C. Therapy.

International wound journal, 2008, Volume: 5, Issue:5

Redon drains are still used to suction wounds for vacuum sealing. Vacuum-assisted closure (V.A.C.((R)); Kinetic Concepts Inc, San Antonio, TX) is a computer-controlled therapy system for delivering topical negative pressure therapy. The efficiency of V.A.C. in the treatment of pressure ulcers was prospectively studied in a randomised controlled trial in which patients with pressure ulcers were randomly assigned to negative pressure wound therapy (NPWT) using either V.A.C. or Redon bottles. The target parameters were absolute and relative proportion of wound area consists of granulation tissue, fibrin and necrosis. Other outcome measures were the number of dressing changes and time invested using each system. The study was terminated after a post hoc analysis after inclusion of ten patients because of the significantly better results when using V.A.C., and the substantially larger care effort needed in the Redon group compared with the V.A.C. group. An increase in surface granulation tissue of 54% was observed in the V.A.C. group, and a reduction in the Redon group (P = 0.001). The Redon group showed an increase in fibrin tissue at the wound base of 21.8%, whereas in the V.A.C group, a 27% reduction was observed (P = 0.035). Necrosis was reduced in the V.A.C. group, but this difference did not reach significance. Redon bottles are not a good alternative for V.A.C. therapy for delivering NPWT.

Topics: Aged; Aged, 80 and over; Austria; Debridement; Drainage; Equipment Design; Equipment Failure; Fibrin; Granulation Tissue; Humans; Necrosis; Negative-Pressure Wound Therapy; Nursing Evaluation Research; Pressure Ulcer; Severity of Illness Index; Therapy, Computer-Assisted; Time and Motion Studies; Treatment Outcome; Workload; Wound Healing

2008