fibrin and Postpartum-Hemorrhage

fibrin has been researched along with Postpartum-Hemorrhage* in 20 studies

Reviews

1 review(s) available for fibrin and Postpartum-Hemorrhage

ArticleYear
Disseminated intravascular coagulation and consumption coagulopathy in obstetrics.
    Obstetrics and gynecology annual, 1974, Volume: 3, Issue:0

    Topics: Acute Disease; Animals; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Embolism, Amniotic Fluid; Female; Fetal Death; Fibrin; Fibrinogen; Fibrinolysis; Hemoglobinometry; Humans; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic; Puerperal Disorders; Shock, Septic; Thrombin

1974

Trials

1 trial(s) available for fibrin and Postpartum-Hemorrhage

ArticleYear
Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study.
    Blood, 2014, Sep-11, Volume: 124, Issue:11

    This prospective, observational study investigated the utility of Fibtem A5 and Clauss fibrinogen as predictors of progression of postpartum hemorrhage (PPH). A consecutive cohort of 356 women experiencing 1000 to 1500 mL PPH was recruited. Fibtem and fibrinogen were measured and subsequent transfusions, invasive procedures, and bleed volume recorded. Women progressing to 8 U blood products (red blood cells [RBCs] + fresh frozen plasma [FFP] + platelets) had a median (interquartile range) fibrinogen and Fibtem A5 of 2.1 (1.8-3.4) g/L and 12 (7-17) mm, respectively, compared with 3.9 (3.2-4.5) and 19 (17-23) for those not progressing. On multivariate analysis, Fibtem was an independent predictor for progression to bleeds >2500 mL (95% confidence interval [CI], 0.85 [0.77-0.95]). Receiver operating characteristic area under the curve (95% CI) for progression to RBC transfusion was 0.67 (0.60-0.74) for fibrinogen and 0.61 (0.54-0.68) for Fibtem, and progression to >2500 mL was 0.71 (0.61-0.81) and 0.75 (0.66-0.85) for fibrinogen and Fibtem, respectively. Fibtem A5 <10 mm was associated with more prolonged bleeds (median [95% CI], 127 [44-210] compared with 65 [59-71] minutes; P = .018) and longer stay in the high-dependency unit (23.5 [18.4-28.5] compared with 10.8 [9.7-11.8] hours). Fibtem is a rapidly available early biomarker for progression of PPH.

    Topics: Adult; Biomarkers; Blood Coagulation; Erythrocyte Transfusion; Female; Fibrin; Humans; Postpartum Hemorrhage

2014

Other Studies

18 other study(ies) available for fibrin and Postpartum-Hemorrhage

ArticleYear
Rotem in postpartum hemorrhage.
    Blood, 2014, Sep-11, Volume: 124, Issue:11

    Topics: Blood Coagulation; Erythrocyte Transfusion; Female; Fibrin; Humans; Postpartum Hemorrhage

2014
[Postpartum hemorrhage: hazard... or linkage?].
    Revue medicale de la Suisse romande, 1990, Volume: 110, Issue:9

    Topics: Adult; Female; Fibrin; Humans; Hysterectomy; Placenta Accreta; Postpartum Hemorrhage; Pregnancy; Recurrence; Reoperation; Uterine Inertia

1990
[Legal abortion and hemostasis. Histological examinations and comparison to post partum hemostasis (author's transl)].
    Archiv fur Gynakologie, 1976, Apr-29, Volume: 220, Issue:4

    30 women were examined to determine the hemostasis during the legally induced abortion. The blood coagulated in the intervillous spaces while the fetus is removed. Immediately after the termination of the curettment the nidation area is covered by filaments of fibrin and incorporated erythrocytes. More frequent as post partum platelet thrombi occur especially in the area of decidua parietalis. The intravascular findings are similar to post partum changes after the removal of the placenta. Obstruction clots of the spiral arterioles contain fibrin deposits, pletelet thrombi and erythrocytes (mixed form of thrombi). Residual decidua and trophoblast cells are seldom involved in the obturation of the vessels. The traumatic damages of the uterine wall are described (extravascular fibrin deposits, interstitial bleeding, succulent tissue a.s.o.).. Hemostasis was studied in 30 women during legal abortion. The blood coagulated in the intervillous spaces while the fetus is removed. Immed iately after the termination of the curettage the nidation area is covered by filaments of fibrin and incorporated erythrocytes. Platelet thrombi occur especially in the area of decidua parietalis, more frequently than in the postpartum. The intravascular findings are similar to postpartum changes after the removal of the placenta. Obstru ction clots of the spiral arterioles contain fibrin deposits, platelet thrombi and erythrocytes (mixed form of thrombi). Residual decidua and throphoblast cells are seldom involved in the obturation of the vessels. The traumatic damages of the uterine wall are described (extra vascular fibrin deposits, interstitial bleeding, succulent tissue a.s.o.). The local hemostatic differences are closely related to the changes and reactions of the endometrium in early pregnancy.

    Topics: Abortion, Legal; Adult; Biopsy; Blood Platelets; Female; Fibrin; Hemostasis; Humans; Placenta; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Pregnancy Trimester, First; Time Factors; Uterus

1976
Postpartum renal failure and the hemolytic-uremic syndrome.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Acute Kidney Injury; Adult; Arteries; Capillaries; Cell Division; Epithelial Cells; Epithelium; Female; Fibrin; Hemolytic-Uremic Syndrome; Humans; Infarction; Kidney Glomerulus; Postpartum Hemorrhage; Pregnancy; Puerperal Disorders

1973
[The alcohol plasma gelation test in the diagnosis of disseminated intravascular coagulation].
    La Presse medicale, 1971, May-15, Volume: 79, Issue:24

    Topics: Abortion, Septic; Blood Coagulation Disorders; Disseminated Intravascular Coagulation; Ethanol; Female; Fibrin; Hematoma; Humans; Leukemia; Liver Cirrhosis; Methods; Neoplasms; Phlebitis; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic; Sepsis

1971
[Examination of fibrinolytic activity in obstetrics by means of a modified method of fibrin-agar plates (Astrup-Müller method)].
    Bratislavske lekarske listy, 1971, Volume: 56, Issue:1

    Topics: Agar; Blood Coagulation Disorders; Blood Coagulation Tests; Female; Fibrin; Fibrinolysis; Humans; Methods; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic; Serologic Tests

1971
Uterine hypotonia.
    British medical journal, 1971, Sep-11, Volume: 3, Issue:5775

    Topics: Amniotic Fluid; Aprotinin; Female; Fibrin; Humans; Postpartum Hemorrhage; Pregnancy; Uterine Inertia

1971
Fibrinolysis and abruptio placentae.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1969, Volume: 76, Issue:6

    Topics: Abruptio Placentae; Aminocaproates; Animals; Aprotinin; Blood Coagulation Disorders; Blood Transfusion, Intrauterine; Delivery, Obstetric; Extraembryonic Membranes; Female; Fetus; Fibrin; Fibrinogen; Fibrinolysis; Humans; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic; Rabbits; Uterine Diseases; Uterus

1969
Fibrin degradation products in normal and abnormal pregnancy and parturition.
    British medical journal, 1969, Jul-19, Volume: 3, Issue:5663

    The levels of fibrin, fibrinogen degradation products (F.D.P.) in the serum were investigated in normal pregnancy and parturition, after caesarean section, and in patients with abruptio placentae, eclampsia, intrauterine death, and post-partum haemorrhage. No significant change occurred during normal pregnancy, but a highly significant increase was found during labour and again during the first week after normal delivery. After caesarean section the levels of F.D.P. were increased two to four hours after operation, and substantially higher levels were found three to eight days after operation than after normal delivery. High levels of F.D.P. were associated with abruptio placentae and eclampsia, and increased levels after intrauterine death and post-partum haemorrhage.An excess of F.D.P. with diminished or normal systemic fibrinolytic activity suggests that local intravascular fibrin deposition and fibrinolysis occur in normal parturition and in these complications of pregnancy. The very high levels of F.D.P. found in abruptio placentae will be important in the pathogenesis of the defective haemostasis that may accompany this complication.

    Topics: Abruptio Placentae; Cesarean Section; Eclampsia; Female; Fetal Death; Fibrin; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Labor, Obstetric; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications

1969
Placental infarction and toxemia of pregnancy.
    American journal of obstetrics and gynecology, 1967, Oct-01, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Female; Fetal Death; Fibrin; Humans; Infarction; Placenta; Postpartum Hemorrhage; Pre-Eclampsia; Pregnancy

1967
[Intravascular fibrin precipitation as a lethal pregnancy complication. Report of 4 pertinent clinical cases].
    Geburtshilfe und Frauenheilkunde, 1967, Volume: 27, Issue:8

    Topics: Adult; Blood Coagulation Disorders; Embolism, Amniotic Fluid; Female; Fibrin; Humans; Lung; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic

1967
[Use of fibrin films for the arrest of hemmorhage in the early postpartum period].
    Akusherstvo i ginekologiia, 1967, Volume: 43, Issue:10

    Topics: Female; Fibrin; Humans; Postpartum Hemorrhage; Pregnancy

1967
[SEVERE DEFIBRINATION SYNDROME IN GYNECOLOGY].
    Orvosi hetilap, 1964, Nov-15, Volume: 105

    Topics: Abortion, Induced; Afibrinogenemia; Blood Transfusion; Curettage; Female; Fibrin; Genital Diseases, Female; Gynecology; Hemorrhage; Humans; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Thrombin; Uterine Hemorrhage

1964
[Role of fibrin and fibrinolysis in the integrity of the vascular wall].
    Hemostase, 1963, Volume: 3

    Topics: Capillary Permeability; Female; Fibrin; Fibrinolysin; Fibrinolysis; Hemorrhage; Histamine; Humans; Postpartum Hemorrhage; Postpartum Period

1963
[Polymerization disorders of fibrin and their clinical significance].
    Folia haematologica; internationales Magazin fur Blutforschung, 1963, Volume: 7

    Topics: Female; Fibrin; Hemorrhage; Humans; Polymerization; Postpartum Hemorrhage; Postpartum Period; Pregnancy

1963
Inhibitors of tissue thromboplastin in the clinical and experimental defibrination syndrome.
    The American journal of the medical sciences, 1962, Volume: 244

    Topics: Afibrinogenemia; Female; Fibrin; Hemorrhage; Humans; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Pregnancy Complications; Thromboplastin

1962
[Generalized hemorrhagic diathesis and vascular fibrin precipitations in the secondary stages of experimental fat embolism].
    Die Medizinische Welt, 1962, Oct-06, Volume: 40

    Topics: Embolism; Embolism, Fat; Female; Fibrin; Hemorrhage; Hemorrhagic Disorders; Humans; Postpartum Hemorrhage; Postpartum Period; Pulmonary Embolism

1962
[Fatal postpartum hemorrhagic syndrome with incoagulability of blood caused by fibrinolysis].
    Il Progresso medico, 1953, Jul-31, Volume: 9, Issue:14

    Topics: Blood Coagulation; Female; Fibrin; Fibrinolysis; Hemorrhage; Humans; Postpartum Hemorrhage; Postpartum Period; Pregnancy

1953