fibrin and Ovarian-Cysts
fibrin has been researched along with Ovarian-Cysts* in 2 studies
Other Studies
2 other study(ies) available for fibrin and Ovarian-Cysts
Article | Year |
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An acquired inhibitor that produced a delay of fibrinopeptide B release in an asymptomatic patient.
An asymptomatic, 29-year-old woman was referred to our hospital before surgery because in the basic study of hemostasis she showed a prolonged thrombin time (TT) and a normal reptilase time (RT). She had not received any anticoagulants so, to account for these abnormal results the presence of an inhibitor or a dysfibrinogenemia was suspected. A 1:1 mixture of the patient's plasma with control plasma did not correct the TT. Dysfibrinogenemia was excluded because the defibrinated plasma retained the inhibitory activity when mixed with normal plasma. When 0.02 mg/ml of Protamine Sulphate (a concentration that neutralizes 1 U/mL of heparin in normal plasma) was added to the patient's plasma, the inhibitory activity did not disappear. IgG from the patient and from normal serum was isolated. The patient's IgG was able to prolong the TT of a normal plasma and of a purified fibrinogen. The patient IgG did not impair the catalytic activity of thrombin, because no difference was observed in the hydrolysis of S-2238 by 1 U NIH human thrombin with normal or patient IgG. The time course of the thrombin-mediated fibrinopeptide-release from normal fibrinogen with the patient's IgG, showed a delay in the fibrinopeptide B (FPB) release without affecting the fibrinopeptide A (FPA) release. This patient has an IgG antibody that delays fibrinopeptide B release of fibrinogen. Topics: Adult; Autoantibodies; Autoimmune Diseases; Female; Fibrin; Fibrinogen; Fibrinopeptide B; Humans; Immunoglobulin G; Ovarian Cysts; Preoperative Care; Protein Binding; Protein Processing, Post-Translational; Thrombin; Thrombin Time | 2007 |
Intra-abdominal adhesions as a manifestation of a fibrotic diathesis.
In 81 patients with fibrous intra-abdominal adhesions there was a high incidence of other lesions in which there was a substantial element of fibrosis. These included chronic peptic ulceration, ovarian cysts, fibrous stenotic lesions, and thickened scars. It is suggested that in some patients a generalized fibrotic tendency as well as local factors may play a part in the pathogenesis of adhesions. Topics: Abdomen; ABO Blood-Group System; Adult; Aged; Chronic Disease; Cicatrix; Constriction; Female; Fibrin; Fibrinolysis; Humans; Male; Middle Aged; Ovarian Cysts; Peptic Ulcer; Tissue Adhesions | 1969 |