fibrin and Leishmaniasis--Visceral

fibrin has been researched along with Leishmaniasis--Visceral* in 2 studies

Other Studies

2 other study(ies) available for fibrin and Leishmaniasis--Visceral

ArticleYear
Hepatitis with fibrin-ring granulomas.
    Infection, 2008, Volume: 36, Issue:4

    We describe a 66-year-old woman hospitalized with fever, fatigue and hepatopathy. In her medical history arterial hypertension (treated with propranolol and lisinopril), diabetes mellitus type 2 (no treatment before admission) and a gout arthropathy were noted wherefore a therapy with allopurinol 300 mg per day has been started 4 months before. Liver biopsy revealed fibrin-ring granulomas, compatible with allopurinol-induced hepatitis. Because of persistence of high fever after stopping allopurinol, steroids (1 mg/kg) were started. Under this treatment, she developed pancytopenia and fever. The bone marrow aspiration revealed Leishmania infantum. A second liver biopsy showed amastigotes and a disappearance of the granulomas. The history revealed a travel to Malta 2 years earlier. Despite adequate treatment with liposomal amphotericin B the patient deteriorated and finally died in septic shock.

    Topics: Aged; Allopurinol; Animals; Biopsy; Bone Marrow; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Fibrin; Gout Suppressants; Granuloma; Humans; Leishmania infantum; Leishmaniasis, Visceral; Liver

2008
Hepatic fibrin-ring granulomas in visceral leishmaniasis.
    Gastroenterology, 1988, Volume: 95, Issue:4

    Hepatic fibrin-ring granulomas and leishmania parasites were found in the liver biopsy specimens of 3 patients with prolonged fever and hepatosplenomegaly. It was recognition of the leishmanias in the liver biopsy specimen that prompted the diagnosis in all cases. There was no evidence of Q fever, Hodgkin's disease, cytomegalovirus hepatitis, or allopurinol treatment, which are the recognized causes of hepatic fibrin-ring granulomas. This report extends the range of etiologies of hepatic fibrin-ring granulomas. As a result, leishmaniasis should always be a consideration to the pathologist and the clinician in the differential diagnosis of fibrin-ring granulomas.

    Topics: Aged; Biopsy; Diagnosis, Differential; Female; Fibrin; Granuloma; Humans; Infant; Leishmaniasis, Visceral; Liver; Liver Diseases, Parasitic; Male; Middle Aged; Q Fever

1988