fibrin has been researched along with Hemangiosarcoma* in 3 studies
3 other study(ies) available for fibrin and Hemangiosarcoma
| Article | Year |
|---|---|
Detection of fibrin generation alterations in dogs with haemangiosarcoma using resonance thrombography.
The objective of the study was to examine the alterations of fibrin generation in dogs with haemangiosarcoma using resonance thrombography. The second objective was to evaluate the sensitivity of this method for the detection of hypofibrinogenaemia and/or increased fibrin(ogen) degradation product (FDP) concentration.. Resonance thrombogram (RTG) measurements with two different instruments were performed in 30 unselected dogs with haemangiosarcoma, 14 of which had decreased fibrinogen and 28 of which had an increased FDP concentration (p<0.0001).. The RTG-reaction time was less sensitive than the fibrin formation time (RTG-f) and fibrin amplitude (RTG-F). The RTG-f and RTG-F indicated reliably a decrease in fibrinogen concentration (sensitivity: 0.93). The sensitivity of detection of increased FDP levels was considerably higher than that of thrombin time. However, false-negative results were found even at FDP concentrations > or =120 mg/l, especially in cases with high fibrinogen level. Both machines showed similar sensitivity.. The results of this study indicate that canine haemangiosarcoma is frequently associated with severe alterations of fibrin generation due to low fibrinogen and high FDP levels leading to distinct RTG abnormalities. The global test RTG reacts sensitively to a decreased fibrinogen level whereas its accuracy to detect FDP concentrations occurring under pathophysiological conditions is limited. A significant alteration of fibrin generation induced by FDPs may not occur until the serum FDP concentration exceeds 60 mg/l. Topics: Animals; Blood Coagulation Factors; Blood Coagulation Tests; Dogs; Fibrin; Fibrin Fibrinogen Degradation Products; Hemangiosarcoma; Platelet Count; Sensitivity and Specificity | 2005 |
[Hemangioendotheliosarcoma of the spleen. A case with hemolytic anemia and defibrination syndrome].
Topics: Anemia, Hemolytic; Blood Coagulation Disorders; Disseminated Intravascular Coagulation; Fibrin; Hemangiosarcoma; Humans; Male; Middle Aged; Phagocytosis; Splenectomy; Splenic Neoplasms; Thrombocytopenia | 1972 |
[Cerebral angioblastoma in advanced age with severe regressive lesions. A histological examination concerning the pathogenesis of the tumour and its regressions].
Topics: Adenocarcinoma; Aged; Brain Neoplasms; Cell Transformation, Neoplastic; Diagnosis, Differential; Fibrin; Hemangiopericytoma; Hemangiosarcoma; Hemosiderin; Humans; Male; Meningioma; Neoplasm Metastasis; Neoplasm Regression, Spontaneous | 1970 |