fibrin and Foreign-Body-Migration

To evaluate the impact of interventional radiological imaging and treatment of central venous port catheter complications.. In this retrospective analysis 429 port catheter dysfunctions were evaluated in 393 port catheter systems for a total of 389 patients over a period of 10 years. The study included 193 (49.1 %) patients with radiologically implanted port catheter systems and 200 (50.9 %) referred patients with surgically implanted port systems. Port catheter dysfunctions were subdivided into early and late complications as well as into non-thrombotic and thrombotic events. After administration of contrast medium, the port system was visualized using digital subtraction angiography. Data were retrospectively collected from the in-house databases and then analyzed descriptively.. 429 contrast media injections via port catheters were performed in 393 port catheter systems. There were 359 (83.7 %) late complications and 70 (16.3 %) early complications. In 299 (69.7 %) cases thrombotic events occurred and 130 (30.3 %) non-thrombotic events were recorded. The most common reason for contrast media injection via port catheter system was port catheter-related thrombosis in 269 (62.7 %) cases. 70 (16.3 %) catheter migrations and 30 (7.0 %) fibrin sheath formations were detected. 18 (4.2 %) port needle malfunctions could be resolved through needle exchange. All 15 (3.5 %) catheter disconnections had to be revised in all cases. Also six port explantations were performed in 6 (1.4 %) catheter fractures.. The possibilities of angiographic imaging and interventional radiological correction of port catheter dysfunctions must be exploited fully in order to avoid premature port explantation.

Topics: Angiography, Digital Subtraction; Catheterization, Central Venous; Catheters, Indwelling; Cohort Studies; Equipment Failure; Female; Fibrin; Fluoroscopy; Foreign-Body Migration; Humans; Male; Phlebography; Radiology, Interventional; Retrospective Studies; Thrombosis

Various surgical techniques for the removal of a foreign body from maxillary sinuses have been reported. However, the access window in the lateral wall of the maxillary sinus cavity is not replaced by a bony wall when sinus grafting is not performed. The replaceable bony window provides an access window into the sinus cavity and maintains the integrity of the lateral wall of the sinus cavity after the removal of a foreign body from the sinus. Saline irrigation and suction are simple and quick techniques to remove foreign bodies from the sinus. This technique does not require special equipment, including that of endoscopy.

Topics: Adult; Blood Platelets; Dental Implants; Fibrin; Follow-Up Studies; Foreign Bodies; Foreign-Body Migration; Humans; Male; Maxillary Sinus; Mucous Membrane; Osteogenesis; Osteotomy; Sodium Chloride; Suction; Surgical Flaps; Therapeutic Irrigation; Tooth Root

Topics: Adult; Angiography, Digital Subtraction; Catheterization, Central Venous; Catheters, Indwelling; Equipment Design; Fibrin; Foreign-Body Migration; Foreign-Body Reaction; Humans; Male; Prosthesis Failure; Pulmonary Artery; Vena Cava Filters; Vena Cava, Inferior

Porcine cross-linked collagen (PermaCol, PCL; TSL, Aldershot, United Kingdom) has been proposed as permanent biomaterial in incisional hernia repair. We evaluated the biocompatibility of PCL in an established animal model.. In 10 Sprague Dawley rats, two hernias per animal were created in the abdominal wall left and right of the linea alba (1.5 cm in diameter), and the peritoneum was spared. The lesions were left untreated for 10 days, until incisional hernias developed. These defects were covered with non-perforated (out-of-the-box, n = 12) or perforated (modified; n = 8) PCL (2 x 2 cm). In a first step, 12 non-perforated implants were tested in a short-term observation period of 17 days. Eight of these non-perforated implants were fibrin sealed (0.3 mL, Tissucol; Baxter, Vienna, Austria), whereas four non-perforated implants were sutured with non-resorbable material. In a second step, perforations were added as modification to PCL to facilitate drainage of fluids, cell ingrowth, and transgression of fibrin sealant. All perforated implants were fibrin sealed and included in a long-term observation period of 3 months. The observation periods allowed the evaluation of the complete degradation of the fibrin sealant fixation after 2 weeks and of the implant integration in a chronic timeframe. Implant sites were analyzed macroscopically and histologically.. All PCL samples elicited strong local inflammation with signs of foreign body reaction. Integration of perforated PCL appeared limited after 3 months. Three animals had to be euthanized prior to intended time points because of transcutaneous migration of implants.. In an experimental model of incisional hernia repair, PCL does not integrate well in the abdominal wall and shows poor biocompatibility.

Topics: Animals; Biocompatible Materials; Collagen; Digestive System Surgical Procedures; Fibrin; Foreign-Body Migration; Herniorrhaphy; Implants, Experimental; Inflammation; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Surgical Mesh; Swine

Topics: Adolescent; Catheterization, Central Venous; Female; Fibrin; Fibrin Fibrinogen Degradation Products; Foreign-Body Migration; Foreign-Body Reaction; Hemostasis; Humans; Incidental Findings; Medical Errors; Plasminogen Activator Inhibitor 1; Radiography, Thoracic; Time Factors

Topics: Anterior Chamber; Aphakia; Fibrin; Foreign-Body Migration; Humans; Iris; Membranes; Postoperative Complications; Pseudophakia; Silicone Oils